• Your daily habits, routines and environmental cues make up your sleep ecosystem, affecting how you fall asleep and stay asleep.
• Melatonin, which helps signal to your brain that it's time to wind down, is important to that ecosystem.
• Better sleep is one of the strongest investments you can make in your health and well-being.

Americans are increasingly focused on optimizing their health, from tracking activity and recovery to managing weight and nutrition. Sleep is the foundation of overall health, supporting mental and physical well-being and reinforcing healthy lifestyle habits.

According to the Centers for Disease Control and Prevention (CDC), more than 30% of U.S. adults regularly get less than the recommended seven to nine hours of sleep each night.¹

Dr. Stephanie Stahl, medical director at Indiana University Health, notes that many people still treat sleep as something they'll fit in if there's time. Stahl is the Sleep Medicine Fellowship Program director and associate professor at Indiana University School of Medicine as well as a member of the Natrol^® Sleep Science Advisory Board.

"Many people think of sleep as the first thing they can sacrifice when life gets busy. But sleep isn't a luxury. It's one of the most powerful tools we have to support our health, mental well-being and daily performance."

But in today's always-on world, packed schedules, constant notifications and late-night scrolling can all work against the body's natural sleep-wake cycle. In fact, 38% of adults say using their phone or tablet before bed to read the news or "doomscroll" makes their sleep somewhat or significantly worse.²

What is keeping you awake?

"One of the biggest misconceptions I hear is that sleep starts when your head hits the pillow," said Stahl. "The truth is that your body has been preparing for sleep all day. Your light exposure, activity, meals, stress and evening routine all influence how prepared your brain and body are for sleep."

She describes this as your sleep ecosystem — the daily habits, routines and environmental cues that work together to influence your body's natural sleep-wake cycle. One of the most important players in that ecosystem is melatonin, a hormone your body naturally produces in response to darkness. Rather than forcing sleep, melatonin helps signal to your brain that it's time to wind down.

Stahl debunks three common sleep myths:

Myth 1: Better sleep starts at bedtime.

Stahl: "Great sleep starts the moment you wake up. Morning sunlight helps regulate your body's internal clock and supports natural melatonin production later that evening."

Myth 2: I'll catch up on sleep this weekend.

Stahl: "Consistency may be just as important as sleep duration. Keeping a regular sleep and wake schedule (yes, even on weekends) helps reinforce your body's natural rhythm."

Myth 3: The eight hours you're asleep are all that matter.

Stahl: "The hour before bed matters, too. A consistent wind-down routine, and dimming the lights and avoiding screen time help prepare your brain and body for quality sleep."

How can small changes in habits aid in falling asleep and staying asleep?

Improving sleep doesn't require overhauling your lifestyle. Stahl recommends focusing on a few consistent habits: Get outside for natural light early in the day, stay physically active, avoid caffeine in the afternoon and evening, maintain a regular sleep schedule and create a cool, dark, quiet sleep environment.

Beyond healthy habits: How to get extra sleep support from supplements

Healthy sleep habits are the foundation of better sleep, but even the best routines can't account for everything. Travel, shift work, changing schedules, stress and age-related changes can all temporarily disrupt your body's natural rhythm.

It's one reason more than 27% of U.S. adults report using melatonin supplements, making it one of the country's most commonly used sleep supplements.³ Melatonin is a well-studied naturally occurring hormone that plays a key role in regulating the sleep-wake cycle.

"One myth I hear is that we don't know enough about the safety of melatonin supplements," said Stahl. "In reality, melatonin has been studied and widely used for more than 30 years, and research across a range of doses and durations of use supports its role as a safe, effective and non-habit-forming option for temporary sleep support when taken as directed."

Melatonin is also the No. 1 doctor-recommended ingredient for sleep⁴ and is recognized by experts as a reliable way to help people fall asleep faster and stay asleep longer.*

Because sleep challenges vary from person to person, some people may also benefit from ingredients such as magnesium glycinate, valerian root, GABA or L-theanine depending on their individual needs. Guided by leading sleep experts, including Stahl, Natrol develops science-backed sleep solutions designed to complement healthy sleep habits and support different sleep needs.

The benefits of prioritizing sleep extend well beyond feeling rested — 88% of adults who are satisfied with their sleep report they are flourishing, compared with just 47% of those who aren't.⁵ Better sleep isn't just another wellness goal. It's one of the strongest investments you can make in your overall health and well-being.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

SOURCES:

1. Centers for Disease Control and Prevention. Short Sleep Duration Among Adults. National Center for Health Statistics, U.S. Department of Health and Human Services, 2025, https://www.cdc.gov/nchs/products/databriefs/db559.htm. Accessed 26 June 2026.
2. American Academy of Sleep Medicine. "Americans Are Doomscrolling at Bedtime, Prioritizing Screen Time Over Sleep." American Academy of Sleep Medicine, 2025, https://aasm.org/americans-are-doomscrolling-at-bedtime-prioritizing-screen-time-over-sleep/. Accessed 26 June 2026.
3. Sleep Foundation.org survey. October 2022. https://www.sleepfoundation.org/sleep-news/how-much-melatonin-do-adults-really-take.
4. Based on a 2026 survey of doctors who recommend drug-free sleep support products.
5. National Sleep Foundation. Sleep in America^® 2025 Report. National Sleep Foundation, March 2025.

Accounting for up to 15% of all breast cancer diagnoses, lobular breast cancer is the second most common type of breast cancer, around 50,000 cases a year in the U.S. — but its prevalence has not guaranteed its visibility. Awareness of lobular breast cancer remains disproportionately low among American adults, 4 out of 5 of which have never heard of the disease. And despite having an annual incidence that averages higher for women than brain, kidney, liver, pancreatic or ovarian cancer, a lobular breast cancer diagnosis is foreign to nearly 50% of people personally diagnosed with breast cancer.

This Breast Cancer Awareness Month, it is important to make yourself aware of all types of breast cancer, including lobular breast cancer.

Four key things to know about lobular breast cancer:

• The tumors don't usually form as lumps: Lobular breast cancer, also known as invasive lobular carcinoma (ILC), can have symptoms other than a lump. The cancer cells grow in single-file lines or sheets through the breast tissue rather than forming a distinct, dense lump.
• Detection can be more challenging: Because of the way it presents itself ILC can be less conspicuous on mammography and harder to detect by self-exam. This often means that many patients find their lobular breast cancer undetectable until a biopsy confirms the diagnosis.
• Metastatic lobular breast cancer is hard to monitor and treat: Because lobular breast cancer is hard to image, it makes monitoring metastatic lesions and whether they respond to treatment nearly impossible. It is hard to know when to switch a metastatic lobular breast cancer patient to a new line of treatment to stop tumor growth and sadly, for this same reason, metastatic lobular breast cancer patients are often excluded from clinical trials of new drugs.
• ILC incidences are increasing three times faster across all demographics than any other breast cancer type.

"Unfortunately, despite how relatively common lobular breast cancer is, it has historically been overlooked by research and has no specific treatments," says Dr. Rebecca Shatsky, Professor of Clinical Medicine, UC San Diego Health, Breast medical oncology team leader at Moores Cancer Center and Chair, Lobular Breast Cancer Alliance Scientific Advisory Board.

But, as Lobular Breast Cancer Alliance Executive Director and 8-year ILC survivor Laurie Hutcheson says, "Lobular breast cancer is not rare, has troubling and unique characteristics that are quite different from the more common breast cancer types and urgently needs attention. There are more and more women diagnosed with ILC every day wondering why even now so little is known about lobular breast cancer and when this will change. More attention and research into ILC is critical to changing this narrative and the lives of lobular breast cancer patients everywhere."

To learn more about lobular breast cancer, the only lobular-breast-cancer-focused patient advocacy organization in the country, visit Lobular Breast Cancer Alliance.

Thirty years later, 18-year-old Liam Simmons, of Waxhaw, North Carolina, is preparing for college with the same autoimmune disease.

They are two Black men from different generations, connected by an experience that reaches far beyond visible hair loss.

For Johnson, it began with a trip to the barber. He came home and noticed a bald spot, initially thinking his barber had clipped him. But the hair loss continued. What he couldn't see was what was happening beneath the surface.

Alopecia areata is an autoimmune disease in which the immune system attacks hair follicles. Approximately 700,000 Americans have some form of the disease, according to a 2020 study published in Clinical, Cosmetic and Investigational Dermatology. For Johnson, it progressed to alopecia universalis, resulting in the loss of all his hair.

The impact went much deeper than appearance.

"I didn't like who I saw in the mirror," Johnson says. "Everyone in my family looked a certain way, and I was the person who looked different."

He began hiding beneath hats and du-rags, missing weddings, staying out of pools and pulling back from parties.

Years later, Johnson realized during his commute to work that he had forgotten his du-rag. He could turn around or keep going.

"I had a choice to return and go back to hiding, or I had a choice to live authentically as myself," he says. "I chose to live authentically regardless of the insecurities I faced."

Today, Johnson is an author, coach, father and advocate passionate about increasing representation of Black men living with alopecia areata.

Simmons' experience is different.

Diagnosed at age 2, alopecia has been part of his life for almost as long as he can remember. As a teenager, he became more aware of comments, stares and the ways hair could shape belonging.

"As a Black man, hair is such a big part of identity," Simmons says. A lifelong basketball player, he sometimes feels disconnected when friends, teammates and his brothers talk about hairstyles. "It's something I want to be part of."

Now Simmons is preparing to study political science in college, with plans to pursue law. Starting over socially on a large campus brings a new challenge.

"There's a part of me that's analyzing everybody and trying to figure out who's looking at me and who's not," he says.

Their experiences show why alopecia areata should not be dismissed as cosmetic. Hair loss may be its most visible sign, but the disease can affect identity, confidence, relationships, school, work and daily life.

Their stories are part of Beyond the Mirror, a National Alopecia Areata Foundation^® (NAAF^®) campaign bringing together lived experience and scientific evidence to reveal the full burden of alopecia areata.

"Beyond the Mirror to me is about looking at yourself and not just seeing your physical appearance, but seeing the relationships and the past experiences and all these key defining moments that make you who you are," Simmons says.

Johnson can now look back at the teenager who once hid from the world. Simmons, at 18, is looking forward.

The road ahead will be his own. But he is beginning it in a world where people like Johnson have chosen to be visible, speak openly and make the path a little less lonely for whoever comes next.

Learn more at naaf.org/beyond-the-mirror and join the conversation using #MoreThanHairLoss.

• Radioligand therapy (RLT) delivers targeted treatment directly to cancer cells
• The number of RLT treatment sites has expanded about sevenfold in the U.S.
• Common questions about RLT treatment answered

A cancer diagnosis used to mean choosing between the latest treatment and receiving care close to home. That's starting to change with radioligand therapy (RLT), a treatment that pairs a cancer-seeking molecule with a radioactive particle to deliver targeted treatment directly to cancer cells. RLT is now a mainstream treatment included in NCCN guidelines and no longer limited to academic centers or late-stage therapy, with treatment sites within 30 miles for 90% of eligible patients.^1,2

"Radioligand therapy works like a tracking dog following a scent. We attach a radioactive particle to a molecule trained to recognize one specific target: a marker found predominantly on certain cancer cells," said Dr Nabila Lehachi Waheed, DABR, Medical Director, Radiation Oncologist at the Center for Cancer and Blood Disorders in Fort Worth, Texas, a partner of OneOncology community oncology network. "Once it's in the bloodstream, the molecule follows that target straight to the cancer cells and marks the spot, releasing radiation while limiting the impact on healthy cells nearby."

Answering patients' biggest questions about RLT

Waheed said eligible patients tend to ask the same three questions when they first learn about RLT: Will it work for me? Is it safe? What will my life look like during and after treatment?

"They ask how the treatment finds the cancer cells, how much radiation exposure they and their families will face, and how it will affect their day-to-day life—things like fatigue, nausea, and blood counts," she said.

Many of the answers come back to how precisely the treatment works. RLT is designed to find a specific marker on cancer cells and deliver radiation directly to them. This approach may help limit damage to nearby healthy tissue, although side effects can still occur. Patients and caregivers should ask the care team if they are eligible, what to expect, including possible side effects, safety steps at home, and who to contact with questions.

Waheed walks through each question with patients before they commit to treatment—a level of detail she said matters as much as the science itself.

Advanced RLT treatment, closer to home

Novartis brought the first RLT to market in 2018. Since then, nearly 50,000 patients have been treated, and the number of RLT treatment sites in the U.S. has grown roughly sevenfold—expanding access to patients who need it most.³

Providing this treatment in a community setting means eligible patients have the option to receive advanced, personalized cancer care close to home. It can be woven into a broader treatment plan that includes surgery, systemic therapy, and external radiation, all coordinated in one place.

That matters to Waheed and drove her to become the first physician in Tarrant County to offer RLT to her patients.

"Where you live shouldn't determine the quality of cancer care you receive," Waheed said. "These treatments let patients benefit from options personalized to the biology of their cancer without leaving their families and support systems behind. Innovation only matters if patients can access it."

As RLT continues to expand beyond academic centers and is researched for use in more types of cancer, Waheed sees it as part of a broader shift—one that keeps patients closer to the treatment they need and the people who support them through it.

Dr Nabila Lehachi Waheed has served as a paid consultant to Novartis. This article was developed and sponsored by Novartis.

References

1. Data on file. Patient location. Novartis Pharmaceuticals Corp; 2025.
2. Data on file. Pluvicto desert analysis. Novartis Pharmaceuticals Corp; 2025.
3. Data on file. Pluvicto and Lutathera site opening summary. Novartis Pharmaceuticals Corp; 2026.

Katy is contracted with Bristol Myers Squibb as an unpaid spokesperson, reflecting on her personal experiences with Opdivo Qvantig. Results may vary for others.

Vijay K. Gunuganti, M.D., medical oncologist and hematologist at Texas Oncology, was compensated by Bristol Myers Squibb for his contribution to this article.

For many, retirement represents a long-awaited opportunity to focus on the things that matter most — family, travel, hobbies and the freedom to enjoy life's next chapter. For Katy, that was exactly the plan. After years of balancing work, family responsibilities and busy schedules, she was looking forward to slowing down. She envisioned spending more time playing pickleball, swimming, traveling with her husband and being with her family.

Then everything changed.

A routine medical evaluation led to an unexpected and staggering diagnosis: Stage IV melanoma.

Melanoma is a type of skin cancer. When diagnosed at Stage IV, the cancer cells have spread beyond their original location in the skin to distant lymph nodes or other vital organs. An advanced diagnosis is challenging for any patient to navigate and for Katy, the news was devastating. Suddenly, the retirement that she had spent years planning was overshadowed by uncertainty, fear and difficult decisions about treatment.

"I had so many thoughts running through my mind, especially the fear that if my daughter has a child, they won't have a grandmother," Katy recalls, reflecting on those first difficult days following her diagnosis.

But after the initial shock wore off, Katy made a decision. Rather than letting cancer define her future, she would become an active participant in her care. She wanted to understand her options, partner closely with her healthcare team and make choices that were right for her lifestyle — not simply manage a diagnosis.

Partnering for a path forward

Katy's first step was to find a trusted oncologist with whom she could collaborate to build a treatment plan to target her melanoma. Over the course of her care plan, she was treated with Opdivo Qvantig^® (nivolumab and hyaluronidase-nvhy), an immunotherapy given by subcutaneous (under the skin) injection. As an immunotherapy treatment, Opdivo Qvantig works with the immune system to help fight cancer and is the first approved subcutaneous PD-1 inhibitor. Specifically, Opdivo Qvantig binds to PD-1 receptors on immune cells, which helps the body's natural defenses detect and target the cancer.

Opdivo Qvantig, Opdivo^® (nivolumab) and Yervoy^® (ipilimumab) can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work, which can be serious or life threatening and can lead to death.

INDICATION & SUMMARY OF WARNINGS AND PRECAUTIONS

Opdivo Qvantig is a prescription medicine used alone to treat adults and children 12 years of age and older who weigh 66 pounds (30 kg) or more with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma), after completing combination treatment with intravenous nivolumab and ipilimumab.

Opdivo Qvantig is not indicated for co-administration with Yervoy.

Opdivo is a prescription medicine used in combination with Yervoy to treat adults and children 12 years of age or older with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma).

Opdivo Qvantig, IV Opdivo and IV Yervoy can cause problems that can sometimes become serious or life-threatening and can lead to death. Serious side effects may include lung problems; intestinal problems; liver problems; hormone gland problems; kidney problems; skin problems; eye problems; problems in other organs and tissues; and complications of stem cell transplant, including graft-versus-host disease (GVHD), that uses donor stem cells (allogeneic). Call or see your healthcare provider right away for any new or worsening signs or symptoms. Opdivo is associated with severe infusion reactions.

Please see the Important Safety Information at the end of this article.

Opdivo Qvantig works with the immune system the same way as IV Opdivo but is delivered differently, providing eligible patients and healthcare providers with an additional administration option. Opdivo Qvantig may let patients receive immunotherapy treatment administration quickly* — in as fast as three minutes (injection time of Opdivo Qvantig is three to five minutes) — with an injection under the skin instead of a 30-minute IV infusion of Opdivo into a vein. It is given by a healthcare professional in the stomach area (abdomen) or thigh area. Opdivo Qvantig doesn't need to be administered at an infusion center and may be given at a doctor's office or a site closer to home. Since the medication is injected under the skin and no access to a vein is required, a port may not be necessary.

"For patients navigating an advanced cancer diagnosis, having an administration option that fits their lifestyle is incredibly meaningful," says Dr. Vijay Gunuganti. "Having a subcutaneous option like Opdivo Qvantig allows us to deliver an immunotherapy treatment that works with the immune system in the same way as IV Opdivo, but through a different administration method. While the IV formulation of Opdivo remains a viable option of care, Opdivo Qvantig allows eligible patients to choose another treatment administration method that can be delivered faster*, with a three- to five-minute injection. This addition is a welcome step forward in giving eligible patients more options and may help them integrate cancer care into their daily routines."

*A three- to five-minute injection time of Opdivo Qvantig compared to 30-minute infusion time of IV Opdivo. This does not account for all aspects of treatment and does not include observation time. Actual clinic time may vary.

Embracing a future full of gratitude

Katy's melanoma diagnosis gave her a new perspective, especially on how she viewed accepting help from others.

She welcomed steady support and daily care of her friends, husband and daughter. This helped her deepen her gratitude for the everyday, teaching her to cherish small moments, the people around her and the time they have together. And Katy has much to appreciate — she and her husband recently celebrated their 50th wedding anniversary and are proud new grandparents. She is relishing her role as a grandmother.

By staying active in her own care, Katy felt empowered through having options in how she received treatment.

"Having a choice in how my treatment was administered gave me options to choose from during a time when so much felt out of my hands," Katy shares. "Opting for the subcutaneous injection allowed me to receive treatment in my local doctor's office, making the process easier on my family. I focused on what truly mattered to me: fighting to overcome cancer."

For others who are currently at the beginning of their own cancer journey, Katy offers simple, heartfelt advice: "The antidote to that fear was being grateful," she says. "I am just so full of gratitude for the life that I have."

How to Learn More

To read more inspiring patient and caregiver stories visit: Patient and Caregiver Stories | OPDIVO^® & OPDIVO Qvantig^®

Indications and Important Safety Information

INDICATIONS

OPDIVO QVANTIG^® (nivolumab and hyaluronidase-nvhy) is a prescription medicine used alone to treat adults and children 12 years of age and older who weigh 66 pounds (30 kg) or more with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma), after completing combination treatment with intravenous nivolumab and ipilimumab.

OPDIVO^® (nivolumab) is a prescription medicine used in combination with YERVOY^® (ipilimumab) to treat adults and children 12 years of age or older with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma).

It is not known if OPDIVO QVANTIG is safe and effective in children younger than 12 years of age with melanoma.

It is not known if OPDIVO QVANTIG is safe and effective in children for the treatment of any other cancers.

It is not known if OPDIVO is safe and effective in children younger than 12 years of age with melanoma.

It is not known if OPDIVO is safe and effective in children for the treatment of any other cancers.

IMPORTANT SAFETY INFORMATION FOR OPDIVO QVANTIG, OPDIVO, and YERVOY

What is the most important information I should know about OPDIVO QVANTIG, OPDIVO, and YERVOY?

OPDIVO QVANTIG, OPDIVO, and YERVOY are medicines that may treat certain cancers by working with your immune system. OPDIVO QVANTIG, OPDIVO, and YERVOY can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. These problems may happen anytime during treatment or even after your treatment has ended. You may have more than one of these problems at the same time. Some of these problems may happen more often when OPDIVO QVANTIG or OPDIVO are used in combination with another therapy.

Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:

Lung problems: cough; shortness of breath; chest pain

Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; severe stomach-area (abdominal) pain or tenderness

Liver problems: yellowing of your skin or the whites of your eyes; severe nausea or vomiting; pain on the right side of your stomach area (abdomen); dark urine (tea colored); bleeding or bruising more easily than normal

Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness

Kidney problems: decrease in your amount of urine; blood in your urine; swelling of your ankles; loss of appetite

Skin problems: rash; itching; skin blistering or peeling; swollen lymph nodes, painful sores or ulcers in mouth or nose, throat, or genital area; fever or flu-like symptoms

Eye problems: blurry vision, double vision, or other vision problems; eye pain or redness

Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with OPDIVO QVANTIG, OPDIVO, and YERVOY. Call or see your healthcare provider right away for any new or worsening signs or symptoms, which may include:

• Chest pain, irregular heartbeat, shortness of breath or swelling of ankles
• Confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems, tingling or numbness of the arms or legs
• Double vision, blurry vision, sensitivity to light, eye pain, changes in eyesight
• Persistent or severe muscle pain or weakness, muscle cramps
• Low red blood cells, bruising

Rejection of a transplanted organ or tissue. Your healthcare provider should tell you what signs and symptoms you should report and monitor you depending on the type of organ or tissue transplant that you have had.

Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during treatment with OPDIVO QVANTIG, OPDIVO, and YERVOY. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with OPDIVO QVANTIG, OPDIVO, or YERVOY if you have severe side effects.

What are the possible side effects of OPDIVO QVANTIG, OPDIVO, and YERVOY?

OPDIVO QVANTIG, OPDIVO, and YERVOY can cause serious side effects, including:

• See "What is the most important information I should know about OPDIVO QVANTIG, OPDIVO, and YERVOY?"
• Complications, including graft-versus-host-disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be severe and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with OPDIVO QVANTIG, OPDIVO, or YERVOY. Your healthcare provider will monitor you for signs of complications if you have an allogeneic stem cell transplant.

OPDIVO and YERVOY can cause serious side effects, including:

• Severe infusion reactions. Tell your healthcare team right away if you get these symptoms during an infusion of OPDIVO or YERVOY: chills or shaking; itching or rash; flushing; shortness of breath or wheezing; dizziness; feel like passing out; fever; back or neck pain.

The most common side effects of OPDIVO QVANTIG when used alone in people with renal cell carcinoma include: pain in muscles, bones, and joints; feeling tired; itchy skin; rash; low thyroid hormone levels; diarrhea; cough; stomach-area (abdominal) pain.

The most common side effects observed with nivolumab given into the vein (intravenous nivolumab), which may be experienced with OPDIVO QVANTIG, are shown below.

The most common side effects of OPDIVO, when used alone, include: feeling tired; rash; pain in muscles, bones, and joints; itching; diarrhea; nausea; weakness; cough; shortness of breath; constipation; decreased appetite; back pain; upper respiratory tract infection; fever; headache; stomach-area (abdominal) pain; vomiting; and urinary tract infection.

The most common side effects of OPDIVO, when used in combination with YERVOY, include: feeling tired; diarrhea; rash; itching; nausea; pain in muscles, bones, and joints; fever; cough; decreased appetite; vomiting; stomach-area (abdominal) pain; shortness of breath; upper respiratory tract infection; headache; low thyroid hormone levels (hypothyroidism); constipation; decreased weight; and dizziness.

These are not all the possible side effects. For more information, ask your healthcare provider or pharmacist. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088.

Before receiving OPDIVO QVANTIG, OPDIVO, or YERVOY, tell your healthcare provider about all of your medical conditions, including if you:

• have immune system problems such as Crohn's disease, ulcerative colitis, or lupus.
• have received an organ transplant, including corneal transplant.
• have received or plan to receive a stem cell transplant that uses donor stem cells (allogeneic).
• have received radiation treatment to your chest area in the past and have received other medicines that are like OPDIVO, YERVOY, or OPDIVO QVANTIG.
• have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome.
• are pregnant or plan to become pregnant. OPDIVO QVANTIG, OPDIVO, and YERVOY can harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if OPDIVO QVANTIG, OPDIVO, or YERVOY passes into your breast milk. Do not breastfeed during treatment and for 5 months after your last dose of OPDIVO QVANTIG, OPDIVO, or YERVOY.

Females who are able to become pregnant:

• Your healthcare provider should do a pregnancy test before you start receiving OPDIVO QVANTIG, OPDIVO, or YERVOY.
• You should use an effective method of birth control during treatment and for 5 months after your last dose of OPDIVO QVANTIG, OPDIVO, or YERVOY. Talk to your healthcare provider about birth control methods that you can use during this time.
• Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with OPDIVO QVANTIG, OPDIVO, or YERVOY.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Please see U.S. Full Prescribing Information and Medication Guide for OPDIVO QVANTIG, U.S. Full Prescribing Information and Medication Guide for OPDIVO, and U.S. Full Prescribing Information and Medication Guide for YERVOY.

Clinical Trials and Patient Populations

Checkmate 67T–previously treated advanced or metastatic clear cell renal cell carcinoma with OPDIVO QVANTIG; Checkmate 067–previously untreated unresectable or metastatic melanoma, as a single agent or in combination with YERVOY.

© 2026 Bristol-Myers Squibb Company.
OPDIVO^®, YERVOY^®, and OPDIVO Qvantig^® are trademarks of Bristol-Myers Squibb Company. All other trademarks are property of their respective owners. [1992-US-2600542 10/26]

To help your family enjoy the season with fewer sneezes and sniffles, there are several steps you can take now.

Encourage handwashing

This time of year, you're likely to spend a lot more time indoors, as well as get together with friends and family for holidays and celebrations. Remind everyone in your household that this is the most important time of year to be extra vigilant about washing hands regularly to help keep germs from spreading, especially after returning home from work, school and social gatherings, and always before eating.

Use a germ-killing household disinfectant

Another effective tactic is making sure to disinfect high-touch surfaces throughout your home, including doorknobs, handles, light switches, railings, countertops and more. This is especially important before and after indoor gatherings, and even more crucial when someone in your family is or has been sick.

A trusted household disinfectant like Microban 24, which has just returned to market via Amazon, makes it easier than ever for consumers to incorporate 24-hour bacteria protection into household disinfecting routines.

Microban 24 initially kills 99.9% of cold and flu viruses,* and has the added benefit of killing 99.9% of bacteria that can live on hard, non-porous, non-food contact surfaces up to 24 hours** after treatment, when used as directed.

"Cold and flu season is the prime time when families should become most intentional about cleaning and disinfecting surfaces they touch often," said Jesse Turmenne, senior microbiologist for Microban.

Unlike many products that only kill bacteria with the initial application, both Microban 24 Sanitizing Spray and Microban 24 Multi-Purpose Cleaner offer continuous 24-hour bacteria protection on treated surfaces for up to 24 hours.**

"Ongoing protection for 24 hours after use is a real benefit when disinfecting high-touch and repeated use areas like door handles, light switches, bathroom counters and desks," said Turmenne.

He added that Microban 24 Sanitizing Spray also kills bacteria when used as directed on soft surfaces such as couches, backpacks and coats.

Follow healthy habits

In addition to frequent handwashing and keeping high-touch household surfaces disinfected, following a healthy lifestyle can also help safeguard against the worst that cold and flu season can dish out. For example, making sure to get plenty of sleep, eating nutritious foods, staying hydrated and getting regular exercise are additional ways to support your family's overall health and well-being during the fall and year round.

Visit Microban24.com to learn more about disinfecting your home during cold and flu season.

*Human Coronavirus, Respiratory Syncytial Virus (RSV), Influenza A H1N1.

**When used as directed, effective for 24 hours against Staphylococcus aureus & Klebsiella aerogenes bacteria. Microban 24 Hour Sanitizing Spray does not provide 24-hour residual virus protection.

CHE is an inflammatory condition that can be unpredictable and look different for everyone.¹ If you think you or a loved one may have CHE, here are five important things to know:

1. CHE is not just eczema on your hands

While the condition may coexist with atopic dermatitis, or eczema, CHE is a distinct, chronic, recurring inflammatory skin disease affecting the hands and wrists.^1,2 Clinically, hand eczema is considered chronic when it lasts for more than 3 months or relapses at least twice within a single year.³ It is not uncommon, with 1 in 10 people worldwide living with CHE.¹

2. CHE may appear differently from person to person

Common symptoms of CHE include itching, pain, redness, scaling and fissures.² However, CHE can be challenging to recognize and diagnose because symptoms may present differently from person to person based on the subtype of disease, severity and areas affected.¹ In some people, symptoms may occur on their palms or fingers, while in others, symptoms may be present on the backs of the hands, fingertips or wrists.³

3. Certain triggers may cause symptoms to worsen at times

CHE is associated with skin barrier dysfunction and skin inflammation, leaving skin vulnerable to dryness and irritation.¹ Environmental and occupational factors such as prolonged exposure to water from frequent handwashing, soaps, cleaning agents, detergents, cold/dry climates or latex gloves can trigger flare-ups.³ Other triggers include biological and lifestyle factors like a history of atopic dermatitis, contact allergies, genetic factors, stress or tobacco use.³

4. The impact of CHE goes beyond the skin

Our hands are essential to how we navigate the world — from typing an email or preparing meals to holding a loved one's hand or expressing ourselves creatively.

Because of the highly visible role our hands play in our lives, CHE is often associated with anxiety, low self-esteem, social phobia, embarrassment and self-isolation.¹ In fact, 79% of people living with CHE state it has a negative effect on their mood and 76% report it affects social or leisure activities.⁴ About 50% of people with CHE experience painful symptoms in their hands, like cracks and scaling, which can make it physically difficult to hold or touch everyday objects.²

5. It's important to see a dermatologist if you think you have CHE

CHE may be difficult to manage, but there are ways to help reduce symptoms, support skin health and improve quality of life.

If you think you have CHE, talk to a dermatologist, who can help develop a personalized plan for you. Managing CHE typically depends on the severity and stage of the disease, possible causes or triggers, the area affected and its impact on everyday life. General measures, such as avoiding irritants and allergens where possible, protecting the hands, and using emollients and moisturizers regularly to support the skin barrier can play an important part in this plan.³ Your doctor may also consider medical treatment.

For more information, visit the Chronic World Hand Eczema Day landing page, a resource about CHE created to recognize October 5 as the first World Chronic Hand Eczema Day, an awareness initiative designed to shed light on this persistent condition. While the dedicated day brings crucial global focus to the disease, having a better understanding of CHE, its symptoms, triggers, impact and how to manage it, is important year-round.

References:

1. Dubin C, Del Duca E, Guttman-Yassky E. Ther Clin Risk Manag. 2020;16:1319-1332. doi:10.2147/TCRM.S292504
2. Grant L, et al. Adv Ther. 2020;37(2):692-706. doi:10.1007/s12325-019-01164-5
3. Thyssen JP, et al. Contact Dermatitis. 2022;86(5):357-378. doi:10.1111/cod.14035
4. Ahmed A, et al. Clin Exp Dermatol. 2015;40(5):495-501. doi:10.1111/ced.12619

MAT-99811

ADHD Awareness Month is an opportunity to help individuals and families find trusted resources, build support networks and have more productive conversations throughout their ADHD journey.

Whether it's a child struggling to stay organized at school, a parent trying to understand changing behaviors or an adult feeling overwhelmed by everyday responsibilities, ADHD can affect nearly every aspect of daily life.^1-3 An estimated 7 million children and 15.5 million adults in the United States have been diagnosed with ADHD, yet many still feel unsure where to turn for reliable information, support and guidance.^4,5

Although navigating ADHD can feel isolating at times, no one has to do it alone.

While every person's experience is different, there are practical steps that can be taken to feel more informed, better understood and more prepared. Here are three places to start:

1. Start With Trusted Resources

Getting started is often the hardest part. Reliable educational resources can help people better understand ADHD, learn what questions to ask and discover support available in their communities. StartTalkingADHD.com, a resource from Collegium Pharmaceutical, offers information and tools designed to help individuals and families begin conversations and identify a support network that reflects their everyday needs.

ADHD advocacy organizations, such as Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD), point to the value of trusted information and peer support in helping people feel understood and better equipped to navigate the condition.⁶

"We hear from families that the challenges of ADHD are not limited to one setting or part of the day. They are looking for practical and trusted information and guidance from people who understand ADHD firsthand," said Ingrid McPhilliamy, General Manager, ADHD, Collegium Pharmaceutical. "By making those resources easier to find and share, we can help individuals and families feel more confident in taking the next step that is right for them."

2. Build a Support Network

The impacts and signs of ADHD can often vary from one moment or setting to the next.⁷

"Because ADHD isn't experienced in just one place or at one time of day, support should not come from just one source," said Krista Mason, Director of Development, CHADD. "A network of people who understand an individual's routines and experiences can help them feel supported in the moments that matter most."

This network may include family members, friends, educators, coaches, workplace contacts, community organizations or others who understand your most important routines. The right mix will look different for everyone, but bringing these perspectives together can create a fuller picture of where additional support may be useful.

3. Prepare for More Meaningful Conversations with a Healthcare Provider

Keeping track of everyday experiences can make conversations with healthcare providers more productive.

"It can be helpful to come prepared with a list of things that have felt challenging since you last spoke with your healthcare provider," said Naomi Myrick, MSN, APRN, PMHNP-BC. "Talking through those observations — many of which happen outside of the clinic — can allow for more informed conversations."

Following your visits, use these notes as ongoing reminders to compare growth and challenge areas.

Support needs may evolve as routines, environments and life stages change. Continuing to chat with others in your network about what they are noticing can help keep conversations with your healthcare provider focused on your real-life experience and needs.

ADHD support can begin with a single step. Whether you're seeking answers for yourself or your loved one, finding reliable information, building a trusted support network and preparing for conversations with a healthcare provider can make a meaningful difference.

Visit StartTalkingADHD.com to learn more.

CHADD receives funding from Collegium Pharmaceutical, Inc. Naomi Myrick works with Collegium Pharmaceutical, Inc. as a paid consultant. The views expressed are those of the author(s).

+++

References

1. Sallee FR. Early Morning Functioning in Stimulant-Treated Children and Adolescents with Attention-Deficit/Hyperactivity Disorder, and its Impact on Caregivers. J Child Adolesc Psychopharmacol. 2015 Sep;25(7):558-65.
2. Giannakopoulos, George. "Adolescents with ADHD in the school environment: A comprehensive review of academic, social, and emotional challenges and interventions." Journal of Clinical Images and Medical Case Reports (2025): n. pag.
3. French B, Nalbant G, Wright H, Sayal K, Daley D, Groom MJ, Cassidy S, Hall CL. The impacts associated with having ADHD: an umbrella review. Front Psychiatry. 2024 May 21;15:1343314.
4. Centers for Disease Control and Prevention. Data on ADHD in Children. Available at: https://www.cdc.gov/adhd/data/index.html. Estimate based on 2024 National Survey of Children's Health data. Accessed September 2026.
5. Staley BS, Robinson LR, Claussen AH, et al. Attention-Deficit/Hyperactivity Disorder Diagnosis, Treatment, and Telehealth Use in Adults — National Center for Health Statistics Rapid Surveys System, United States, October–November 2023. MMWR Morb Mortal Wkly Rep. 2024;73(40):890-895.
6. Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD). Uniting in Understanding: The Role of Peer Support. Available at: https://chadd.org/adhd-news/adhd-news-adults/attention-uniting-in-understanding-the-role-of-peer-support/. Accessed September 2026.
7. Pedersen SL, Kennedy TM, Joseph HM, Riston SJ, Kipp HL, Molina BSG. Real-World Changes in Adolescents' ADHD Symptoms within the Day and across School and Non-school Days. J Abnorm Child Psychol. 2020 Dec;48(12):1543-1553.

© Collegium Pharmaceutical, Inc. All rights reserved. PP-PORT-US-0281 10/26

IPF causes irreversible loss of lung function and impacts approximately 150,000 people in the United States. For patients, the lack of effective treatment options makes the need for new therapies especially urgent.

With family history being a risk factor for IPF, Teresa is concerned that her generation, as well as her teenaged daughter, may also face this disease.

Urgent need for rare disease innovation

Motivated by the need for faster progress in rare disease innovation and treatment options, Teresa is raising awareness about the FAIR Act (H.R. 7953), bipartisan legislation that was introduced in Congress in March. The FAIR Act would modernize how the U.S. Food and Drug Administration evaluates therapies for rare and life-threatening diseases.

More than 30 million Americans are living with a rare disease, yet the vast majority of them do not have an FDA-approved treatment. In some cases, Americans with rare diseases are waiting for access to clinical trials and treatments that are already available abroad.

A recent analysis of the FDA's "Novel Drug Approvals" annual reports showed that between 2018 and 2025, 119 novel drugs were first approved outside the U.S. before they received FDA approval. Of these drugs, approximately half were for rare diseases, known as orphan drugs. Additionally, significant delays can exist in bringing new treatments to the U.S., with U.S. drug approvals lagging ex-U.S. approvals by months and sometimes even years.

Giving rare disease patients a voice

"For people with a rare disease like IPF, these types of delays are unacceptable because many of our patients are dying three to five years after diagnosis," says Teresa, chief executive warrior at PF Warriors. "As a community, our greatest challenge is not just living with a rare disease. It's knowing that promising clinical trials and therapies may exist but remain out of reach."

If passed by Congress, the FAIR Act would create a streamlined pathway for the FDA to review and approve early-stage clinical trials and treatments that are already approved by trusted international regulators including the United Kingdom, European Union and Canada. At the same time, the FAIR Act would preserve the FDA's autonomy and safety standards.

"In IPF, 30% of Phase 2 clinical trials are being conducted outside the U.S. The FAIR Act echoes what our community has long known — we need faster access here in the U.S. to clinical trials and therapies that are available in other countries," says Teresa.

Supporting the FAIR Act

At the time of their passing, Teresa's family members did not have access to many of the scientific advances that researchers are pursuing today. The FAIR Act is designed to help ensure that medical advances abroad are made available to American patients more quickly while also encouraging biotechnology companies to increase their investment in U.S.-based clinical trials.

The legislation is gaining support from leading life sciences organizations and patient advocacy groups, which view it as a practical solution to ensure patients do not wait unnecessarily for potentially lifesaving therapies.

For patients and families affected by rare and life-threatening diseases, the FAIR Act represents an opportunity to close access gaps and provide hope.

For more information and to learn how to take action, visit FAIRActNow.com.

Every trip to the grocery store is a balancing act. You're watching the budget and doing quick math on how far each dollar will stretch. You're scanning nutrition labels, planning the week's meals, and hoping what lands in your cart will get eaten. And if you're like me, you're looking for convenient options to pack a nutritious lunch before the school bus arrives.

For generations, bread has helped families manage all that juggling. Friday, October 16, is World Bread Day, and it's a good time to appreciate why.

Nutrition You Can Count On

Bread is more than a convenience. A single slice can deliver fiber, iron, magnesium and B vitamins, which are nutrients many Americans don't get enough of. Grain foods like bread contribute nearly 40% of the dietary fiber in the American diet.

Bread also has a remarkable public health record. Enriched grains, a practice built into bread production for more than 80 years, has played an important role in improving nutritional health. Notably, fortification of enriched grains with folic acid is credited with reducing neural tube birth defects by nearly one-third in the United States. Few foods can claim that kind of a public health achievement.

Affordable, Accessible and Dependable

Bread has connected people across tables and cultures for thousands of years. It is a nutritious staple that makes sense for households at every income level. When grocery bills are stretched, bread is a dependable food that delivers real nutrition for your dollar. In fact, 99% of U.S. households purchased a baked good last year. Baking is clearly woven into everyday American life.

From Farm to Family

That dependable loaf doesn't happen by accident. It is the result of the hard work and dedication of American farmers, millers, bakers and the workers who ensure fresh, affordable bread reaches families every day.

The baking industry employs 800,000 people nationwide. In 2024, commercial bakers invested $15 billion in American-grown ingredients like wheat, corn, sugar and eggs. More than 85% of core baking ingredients come from U.S. farmers and processors, and one-third of all flour milled in this country goes to commercial bakeries.

That partnership supports jobs and strengthens local economies. It also keeps shelves stocked, so families can find affordable, nutritious bread wherever they shop.

The Foundation for Everything Else on the Plate

Bread's greatest strength is its versatility. As the foundation for countless meals, bread brings together protein, vegetables and other nutritious foods. Just consider a single day's menu. Avocado toast with your coffee. A pita stuffed with hummus and veggies for lunch. Tuesday taco night with the family.

Bread helps bring together grains, protein and produce to create nutritious, convenient and portable meals that feed both children and adults. Today's bread aisle also offers more choices than ever, including varieties with added fiber, protein or whole grains to fit different appetites and lifestyles.

A Day to Rediscover Bread

A resolution introduced in the U.S. House of Representatives in 2025 celebrates bread as a "nutritious, affordable, and culturally significant staple food." It encourages Americans to explore new varieties and pair them with nutritious foods. We agree.

On World Bread Day, explore the versatility of bread by trying something new, whether a hearty whole grain, a soft flatbread or a sourdough loaf. Pair it with your family's favorite protein and vegetable to create a nutritious, satisfying meal everyone can enjoy.

Bread is nutritious, affordable and familiar, and American bakers, farmers and millers have kept it at the center of our tables for generations.

For more information about bread's role in a nutritious diet, visit www.bakingfeedsamerica.org.

During Game 2 of the series, DiJonai sustained a major sprain to her midfoot that abruptly and prematurely ended her postseason.

"[Another player] stepped on my foot, and I felt a pop immediately. When I tried to walk again, I couldn't," said DiJonai. "I knew something was wrong."

DiJonai is no stranger to injury. Previously in her career, she tore her ACL (anterior cruciate ligament) in both knees and suffered a shoulder injury, but this time was different. The physical pain was challenging, of course, but the mental pressure to return to peak performance as quickly as possible was immense.

"I was disappointed and felt so guilty because my team needed me, and then I got hurt," she said. "I was blaming myself, wondering what I could have done differently to change the outcome, especially after playing the tape back."

The mental hurdles didn't stop there. As her teammates continued their playoff run, what was meant to be a pivotal moment in her career turned into the beginning of her recovery and pain management journey.

Taking control of her recovery

Following surgery to her foot, DiJonai was prescribed an opioid to manage her acute pain, but she did not like the way she felt after taking the opioid. After talking with her doctor about other pain management options, DiJonai was prescribed JOURNAVX^® (suzetrigine), a prescription medicine used to treat adults with moderate-to-severe short-term (acute) pain, including postoperative pain. It is not known if JOURNAVX is safe and effective in children.¹

"As an athlete, I am mindful of what I put in my body," said DiJonai. "So, when JOURNAVX was introduced to me as a nonopioid option for moderate-to-severe acute pain, that really stood out to me."¹

While patient experiences vary and side effects may occur, JOURNAVX worked to help reduce DiJonai's acute pain during a period that she said could have felt isolating.¹

"I was able to focus on healing and moving through recovery one day at a time," she said. Patients should not take JOURNAVX if they take certain medicines that are strong inhibitors of an enzyme called CYP3A.¹ Patients should ask their healthcare providers if they are not sure.¹

The importance of having nonopioid options

For decades, patients experiencing acute pain were limited to nonsteroidal anti-inflammatory drugs (NSAIDs) or opioids, creating a gap for patients and clinicians seeking other options.²

Each year, around 80 million Americans are prescribed a medicine for acute pain.³ Of these patients, half (about 40 million) are prescribed an opioid to treat their acute pain.³ JOURNAVX is a nonopioid alternative for managing moderate-to-severe acute pain.¹

Looking ahead

DiJonai feels grateful that JOURNAVX was an option for her. Following her recovery, she is looking forward to returning to what she loves — playing basketball.

Her journey is a powerful reminder that acute pain can happen to anyone, at any time, from sports injuries to household accidents to planned surgeries.^4,5 Patients deserve to feel empowered when making treatment decisions. Understanding options can help drive informed conversations with healthcare professionals, allowing patients to be more involved and in control of their care.

"Recovery is about controlling what you can and finding ways to continue to push and move forward," said DiJonai. "Choosing JOURNAVX during a time when everything else felt out of my control was important to me."

JOURNAVX may not be right for everyone; some people may experience side effects.¹ Talk with your doctor about what treatment option is right for you. Visit JOURNAVX.com to learn more.

This article was sponsored by Vertex Pharmaceuticals Incorporated and originally published on 10/13/2026.

What is JOURNAVX?

JOURNAVX is a prescription medicine used to treat adults with moderate-to-severe short-term (acute) pain, including postoperative pain.

It is not known if JOURNAVX is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Do not take JOURNAVX if you take certain medicines that are strong inhibitors of an enzyme called CYP3A. Ask your healthcare provider if you are not sure.

Before taking JOURNAVX, tell your healthcare provider about all of your medical conditions, including if you:

• have liver problems. People with liver problems may have an increased risk of getting side effects
• are pregnant or plan to become pregnant. JOURNAVX may temporarily reduce the chance of females becoming pregnant while on treatment
• are breastfeeding or planning to breastfeed

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Taking JOURNAVX with certain other medicines may affect the way JOURNAVX and the other medicines work and may increase your risk of side effects. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure.

Especially tell your healthcare provider if you take:

• hormonal birth control medicine (contraceptives) containing progestins other than levonorgestrel or norethindrone as they may not work as well during treatment with JOURNAVX. Use nonhormonal contraceptives such as condoms or other forms of hormonal birth control during treatment and for 28 days after you stop taking JOURNAVX
• medicines that are substrates of the CYP3A enzyme as they may become less effective during treatment with JOURNAVX. Your healthcare provider may need to adjust the dose of your medicine when starting or stopping JOURNAVX

What should I avoid while taking JOURNAVX?

Do not take food or drink containing grapefruit during treatment with JOURNAVX.

What are the possible side effects of JOURNAVX?

The most common side effects for patients treated with JOURNAVX included itching, muscle spasms, increased blood level of creatine phosphokinase, and rash.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all of the possible side effects of JOURNAVX.

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Please see full Prescribing Information, including Patient Information, for JOURNAVX.

Sources

1. JOURNAVX [prescribing information]. Vertex Pharmaceuticals Incorporated. Boston, MA; January 2026.

2. Blondell RD, Azadfard M, Wisniewski AM. Pharmacologic therapy for acute pain. Am Fam Physician. 2013;87(11):766-772.

3. Lopez A, Menzie AM, Kenderes M, Rubin JL. A real-world database analysis of the prevalence of pain medication use in the United States. PAIN Reports. 2026;11(1):e1396. doi:10.1097/PR9.0000000000001396

4. "Ouch, that hurts!" The science of pain. NIH MedlinePlus Magazine. Accessed October 1, 2026. https://magazine.medlineplus.gov/article/ouch-that-hurts-the-science-of-pain

5. Pain management center. International Association for the Study of Pain (IASP). Accessed October 1, 2026. https://www.iasp-pain.org/resources/toolkits/pain-management-center/chapter1/

JOURNAVX is manufactured for Vertex Pharmaceuticals Incorporated.
JOURNAVX, Vertex, and the Vertex triangle logo are registered trademarks of Vertex Pharmaceuticals Incorporated.
© 2026 Vertex Pharmaceuticals Incorporated | VXR-US-43-2600419 (v1.0) | 10/2026

SCA is caused by an electrical problem with the heart that causes a dangerously fast heart rhythm. This causes the heart to quiver rather than pump blood. When the heart stops pumping blood, oxygen cannot reach the body and brain. Every year in the United States, 436,000¹ lives are claimed by SCA. That's equal to one life every 90 seconds.² Connor knows just how quickly those statistics can become personal.

"I was down for five minutes before paramedics were able to jump-start my heart," Connor recalls. "Luckily, an off-duty firefighter administered CPR until paramedics arrived."

Connor, who played three seasons of professional football and won 27 games as the all-time winningest quarterback in his Division I college football program's history, had no underlying heart conditions or personal history of heart disease when he collapsed on September 17, 2025. While often associated with older adults or those with known heart disease, sudden cardiac arrest can strike even young, healthy individuals — including elite athletes.³

"It was shocking — when you spend most of your life as an athlete competing at the highest level, something like sudden cardiac arrest just isn't in your playbook," remarked Connor.

As part of his recovery, Connor looked for answers around the cause of his cardiac arrest. Through multiple tests and evaluations, Connor's physicians confirmed he had no preexisting conditions that might have led to SCA. Still, Connor took a proactive approach to guard against future SCA events after his doctor recommended he would be a good candidate for an implantable cardioverter defibrillator (ICD), a device implanted inside the chest that is capable of treating sudden cardiac arrest and abnormal heartbeats with a high-power shock.

Within weeks of suffering his sudden cardiac arrest, Connor received the Aurora EV-ICD™ (extravascular implantable cardioverter-defibrillator) system, a newer defibrillation technology designed to continuously monitor the heart and deliver lifesaving therapy if a dangerous heart rhythm occurs. Unlike traditional implantable defibrillators that require the use of leads (thin, insulated wires that monitors the heart's rhythm and carries treatment from the defibrillator when needed) threaded into the heart through blood vessels, the Aurora EV-ICD is uniquely designed with the lead placed outside the heart and veins to minimize the risk of certain downstream lead complications, while still providing the benefits of traditional defibrillator systems, including a similar size, shape, and longevity. In addition to providing appropriate shock if needed to treat dangerously fast heart rhythms, the Aurora EV-ICD system can also deliver low-voltage pacing pulses to the heart called anti-tachycardia pacing to terminate potentially dangerous rhythms to restore the heart's normal rhythm without a shock.⁴

For Connor, the unique placement of the Aurora EV-ICD system — below the left armpit with the lead placed below the breastbone — was a critical factor in the device selection process with his care team.

"As an active individual without other health conditions, I felt that having a defibrillator system that allowed for more freedom of movement and less risk for lead-related complications down the road was the best option for me," said Connor.

The device, which acts as a protective insurance policy against future cardiac events, allows Connor to get back to the activities he enjoyed before the SCA event like playing with his kids and golfing with his friends — now with a renewed peace of mind.

Today, a year after Connor's cardiac event at the flag football game and subsequent defibrillator implant, he's using his experience and story to give back to communities in South Carolina to help others that may not realize SCA can happen without warning. After surviving a sudden cardiac arrest thanks to bystanders who acted quickly, Connor founded HRTHUDL to help more people recognize SCA and equip communities with emergency response resources that can save lives.

To learn more about sudden cardiac arrest and potential treatment options, visit Medtronic.com/sca. To learn more about HrtHudl and its mission of helping address sudden cardiac arrest through preparation and resources, visit www.HrtHudl.org.

If you are at risk of sudden cardiac arrest, always talk to your doctor about risks, diagnosis, and treatment information. For important safety information, visit Medtronic.com/evicd. This is one patient's experience; results may vary. HRTHUDL received a Medtronic donation to support its mission of preparing communities to respond to sudden cardiac arrest.

¹ American Heart Association. CPR Facts and Stats. Heart.org. Accessed December 19, 2024.

² https://www.cardiosmart.org/topics/sudden-cardiac-arrest

³ Lear A, Patel N, Mullen C, et al. Incidence of Sudden Cardiac Arrest and Death in Young Athletes and Military Members: A Systematic Review and Meta-Analysis. Journal of Athletic Training. 2022;57(5):431-443. https://doi.org/10.4085/1062-6050-0748.20

⁴ https://www.nejm.org/doi/full/10.1056/NEJMoa2206485

• A shift in pace, whether it's a new season, a busier week or a trip, offers a natural checkpoint to recommit to a routine.
• Anchoring a new habit to something you already do makes it easier to stick with, even when life gets busier.
• Wanting to shake up a routine doesn't have to mean an overhaul. Look for products backed by third-party validation to shop your values with confidence.

As summer's relaxed pace gives way to a busier season — after-school extracurriculars starting again, longer commutes as offices fill back up and one last trip before the weather turns — daily routines are often the first thing to slip.

The instinct when a schedule gets busier is often to overcorrect, whether it's a whole new morning routine or a completely different approach to meals. However, it's more effective to keep to a few things that work.

Anchor new habits to something you already do

The easiest way to make a new habit stick is to tie it to one that already happens on autopilot, such as taking vitamins right after your morning coffee or reviewing the next day's schedule while getting ready for bed. Pairing a new habit with an existing one makes it feel automatic instead of like one more thing to remember.

Refresh your routine without reinventing it

Sometimes a shift in pace comes with the itch to try something new, and small swaps are a way to add some freshness to a routine without overhauling it. Swapping in a new product or everyday essential is one of the easiest ways to do that without adding an extra step.

Toothpaste is one of the simplest swaps to make, and it's an easy way to shop your values while you're at it. Keep an eye out for brands backed by third-party certifications like the B Corp Certification, awarded by the nonprofit BLab, which verifies a company's social, environmental and governance impact every three years. In plain terms, it's how you know a brand is committed to responsible business practices that benefit people and the planet, not just shareholders.

Tom's of Maine is a certified B Corp. From sourcing naturally derived ingredients to dedicating 10% of its annual profits to protecting nature, the brand holds itself to the high standards B Lab sets because it believes business should be a genuine force for good.

"Being a Certified B Corp reflects the standards we've held ourselves to for more than 50 years — from the ingredients we source to how we treat our people and our communities," said Michelle Waring, Steward for Sustainability and Everyday Good at Tom's of Maine. "For anyone trying to make more thoughtful choices, it's a reliable signal that a company's impact has been independently verified."

Plan ahead for busy days

Travel, early mornings and packed weeks are when habits are most likely to fall off, often because of convenience. The easiest way to keep a routine going while traveling is to stick with products that are simple to pack and go. Tom's of Maine's toothpaste and deodorant are designed to travel just as easily as they fit into an everyday routine, so there's no need for another purchase before heading out the door.

A busier season does not have to mean starting over. With a few small, consistent choices, the routines that already work can keep working, no matter how packed the schedule gets.

To learn more about Tom's of Maine's natural personal care products, ingredient sourcing and safety standards, visit www.tomsofmaine.com and www.tomsofmaine.com/pages/our-mission.

1. Artichokes are an easy and tasty way to eat more fiber

Fibermaxxing has been getting a lot of attention lately, and for good reason. According to UCLA Health, increasing your fiber intake can help lower cholesterol and reduce your risk of developing several chronic diseases. That said, only 5% of U.S. adults eat the daily recommended amount of fiber.

The good news is that artichokes are a fiber-rich food. Just one medium-sized artichoke contains 7 grams of fiber, roughly one-third of your daily fiber needs. By adding artichokes to your meals, you're improving your fiber intake, one meaty leaf at a time.

2. They're a whole food with a whole lot of nutrients

Nutrient-dense artichokes are a whole food that is as good for you as it is delicious. The veggie's prebiotics and probiotics can improve gut health and balance blood sugar, while its antioxidants support healthy aging. They're also high in magnesium, which can support better sleep.

3. Artichokes are simple to prepare and easy to add to your meals

If you've never cooked an artichoke, you'd be surprised by how simple the vegetables are to prepare. Start by giving them a good rinse and light scrub. Then, snip the top, trim off the end of the stem and remove any small leaves around the base.

Now that your artichokes are clean, you can steam, boil, grill, air fry, microwave or slow cook them. The simplest way to eat artichokes is to dress them with lemon, olive oil and seasonings of your choice, then bake.

Once cooked, you can cool, cover and refrigerate the artichokes so you can incorporate them into your meal plan throughout the week. You reheat and serve them with a savory dip, toss the hearts into salads and grain bowls, or grill them alongside fish or chicken.

An artichoke producer with deep roots

Are you ready to start your artichoke adventure? When searching for artichokes in the produce department, make sure to choose ones from a brand with a history of quality and care like Ocean Mist Farms.

Since 1924, the company has grown to become the largest grower and supplier of fresh artichokes in North America. Its ongoing commitment to thoughtful varietal development and selection, combined with sustainable farming practices, helps ensure the exceptional quality, flavor and year-round availability of its flagship crop. To learn more and discover delicious artichoke recipes, visit OceanMist.com.

During McConnell's bike ride, one shoe slipped and got stuck in the bike's front fork. The bike stopped, but McConnell didn't. He pitched forward and landed on the right side of his head.

"In that moment, I couldn't move," McConnell said. "I was completely frozen. The only thing I could feel was my right pinky."

In the emergency room, doctors found fractures to his C1 and C2 vertebrae and informed McConnell that he might never walk again, if he survived at all.

Luckily for McConnell, his situation wasn't as dire as his original prognosis. Upon further examination, he was diagnosed with spinal shock, a temporary loss of reflexes, muscle movement and feeling below the spinal injury. By the time his wife arrived, McConnell was able to move his arms. Just one week after the accident, McConnell walked 2 miles into town.

Although McConnell's paralysis was brief, the accident left him with a profound sense of gratitude.

Five months later, still in rehab and wearing a brace, McConnell spotted an article in the Sunday paper about the Christopher & Dana Reeve Foundation — an organization dedicated to curing spinal cord injury by advancing innovative research and improving the quality of life for individuals and families impacted by paralysis. As he read on, McConnell discovered that the Foundation needed runners for the New York City Marathon, which would take place exactly one year to the day after his accident.

"This was a sign," he said. "In that moment, I decided I was going to do it." He immediately called four friends who had been helping him recover from the accident and they all jumped in to train and run the marathon together.

That fall, in 2006, McConnell joined Team Reeve, completed the marathon and raised $50,000 for the Foundation. More importantly, he got to know the Foundation's work and the people behind it. The next year, he raised $100,000.

"The Reeve Foundation symbolizes faith and belief that change will continue to happen — that we can make it easier for people living with spinal cord injury and those who care for someone with paralysis to navigate their journeys, provide hope and direction, and help them live full lives," he said. "There is no end to this endeavor; it is a continuum, moving forward every day: What's next? What's new?"

Since 2006, McConnell has run nine marathons for Team Reeve and recruited dozens of friends to join him along the way, helping him to raise several million dollars for spinal cord injury research. But his work didn't stop with Team Reeve. McConnell joined the Foundation's board and has served for 20 years, helping guide and support its mission.

He has championed Reeve's drive to improve quality of life for people with injuries through the extraordinary work of the National Paralysis Resource Center (NPRC); funded by the Administration for Community Living and administered by the Reeve Foundation, the NPRC is the only national program that directly serves the 5.4 million Americans living with paralysis. Mconnell personally introduces newly injured individuals and families to its vital services.

"People outside our community do not understand how devastating a spinal cord injury can be," he said. "Everything changes in an instant. Everything for you, for your family, potentially for your professional future, your personal future, your financial well-being. Everything changes in a minute. We get to make a difference."

More than a race

As McConnell's story shows, a marathon is more than just a race, and Team Reeve is more than a running group. As the Foundation's peer-to-peer fundraising program, Team Reeve supports spinal cord injury research and better quality of life for people and families affected by paralysis. Fundraisers enter major races — including the Boston, Chicago and New York City marathons — while supporters can create local events and personal challenges. Together, Team Reeve participants have raised more than $13 million to advance research and help people navigate daily life with paralysis.

Beyond fundraising and raising awareness, these endurance events connect the spinal cord injury community. Families, friends and advocates come together to support one another and Team Reeve's vision: a world in which spinal cord injury does not result in paralysis and paralysis does not result in diminished quality of life.

Every runner has a why

Every person who runs with Team Reeve has their own reason for running. For Patrick Yalon, running became a way back from a surfing accident that caused a C3-C5 injury and left him unsure whether he would walk again. He still lives with nerve pain, but movement returned a measure of control.

"One step became another. Walking became running," said Yalon, who is currently training for New York. "To go from not knowing if I would walk again to running through New York City for the spinal cord injury community is something I will never take for granted."

Like Yalon, Ulrika Holmquist is also running to rebuild her life. A 2025 racing accident ended her career as a professional jockey and resulted in three spinal surgeries. Through running, she was able to restore her strength and more.

"Running became a turning point in my recovery," said Holmquist, who is training for the 2026 TCS New York City Marathon. "It gave me back confidence, purpose and belief in myself."

For some Team Reeve members, their "why" is a loved one. Erica Bazerkanian, for example, runs for her father. Through team #IAMSTONE, she has raised $215,000, while her company, Bold&Zeal, donates 10% of purchases to the Foundation.

"Charity running is not just something I do," she said. "It is part of who I am. I run to raise awareness, fund progress and honor my father's legacy. The New York City Marathon is my way of turning pain into action, one step at a time."

For Marea Narsavage, her "why" begins with gratitude. As a Navy veteran, endurance athlete, altruistic living kidney donor and Angel Runner, she treats physical ability as a chance to serve others.

"Running the New York City Marathon is about far more than crossing a finish line," she says. "For me, it is an opportunity to raise awareness, give back and use my physical ability to help those who have not been given the same opportunities. It is about living with gratitude and turning that gratitude into action."

Team Reeve's starting line also welcomes athletes who move differently. Stacey Mahdavian — who became paralyzed in a car accident 36 years ago — tackles race courses on a handcycle, while her daughter Stacia runs beside her as a guide. This mother-daughter partnership captures Team Reeve at its best, a combination of athletes living with paralysis, families and supporters moving toward one goal.

The next starting line

Every participant's "why" differs. But whether they're running to reclaim their identity, in memory of a loved one or in gratitude, each Team Reeve member's story widens the circle of support, funds and community.

Team Reeve will gather next at the 2026 Bank of America Chicago Marathon on Oct. 11 and the 2026 TCS New York City Marathon on Nov. 1, followed by Boston and London in April 2027.

Every mile starts with a reason, and every reason can become action. To learn more, support an athlete or start a fundraiser, visit TeamReeve.org.

Key takeaways:

• Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic disease that causes the liver to produce insufficient or dysfunctional alpha-1 protein, which can leave the lungs less protected from infection and pollutants.¹
• Alpha-1 can affect lung health and lead to serious lung diseases like COPD or emphysema.² Risk can be impacted by multiple factors such as levels of Alpha-1, lifestyle and environment.
• The condition can be difficult to diagnose, because its symptoms can resemble those of other respiratory diseases.²
• People with COPD, people with asthma and airflow obstruction that doesn't fully reverse with treatment and family members of anyone with Alpha-1, should ask about getting tested.²

Daryl Kunz loves distance cycling. By age 54, he had clocked thousands of miles annually, winning a regional championship in a 24-hour bike race and several other medals. He was used to cycling long distances, and considered a "century" (100 miles) to be an enjoyable outing. But one day, while enjoying a brisk 60-mile ride, Daryl experienced shortness of breath and wheezing for the first time.

Daryl's symptoms led to several years of frustration. Doctors prescribed medications for asthma and tested him for potential heart conditions, bringing Daryl no closer to understanding what was really going on.

"I went through four years of searching and changing my lifestyle, making me fear I could potentially lose something I absolutely love doing," said Daryl.

His pulmonologist finally tested him for Alpha-1 antitrypsin deficiency (Alpha-1), a rare genetic disease that can impact lung health and cause conditions like chronic obstructive pulmonary disease (COPD).² Daryl learned that his lung capacity was reduced to 58%, but it was likely that his avid cycling helped him to stay as healthy as possible, despite his condition.

"Without knowing it, my passion for cycling actually helped slow the damage to my lungs," said Daryl. "This made me realize how lucky I was to receive my diagnosis when I did, so I could get back on track."

What is Alpha-1?

Alpha-1 occurs when the body cannot make or use enough alpha-1 antitrypsin,¹ a protective protein made in the liver. This protein travels through the bloodstream to the lungs, where it helps protect lung tissue from damage. When alpha-1 protein levels fall below the normal range, individuals may be at an increased risk for lung disease. This risk may be impacted by several factors, including an individual's genetics, lifestyle and environmental exposures.²

An estimated 70,000-100,000 people live with severe Alpha-1 in the U.S., but as many as 90% of these individuals haven't been diagnosed.³ Alpha-1 is one of the most underdiagnosed genetic diseases in the world, and can take as long as eight years to be correctly diagnosed.⁴

Ways Alpha-1 can affect daily life

Common symptoms of Alpha-1 are mostly breathing related, including:⁵

• Shortness of breath/wheezing
• Chronic cough
• Tiredness/fatigue
• Frequent respiratory infections like cold or flu

Alpha-1 can also affect the liver,⁶ which may cause symptoms like jaundice (yellowing of the skin), weight loss, vomiting and more. The similarity of Alpha-1 symptoms with many common lung conditions, including COPD, emphysema, asthma and bronchiectasis can make it difficult to diagnose it accurately. And while Alpha-1 is often associated with lung and liver complications, and in some cases can impact other parts of the body.²

If the disease remains unaddressed, Alpha-1 leaves patients at continued risk for potential irreversible lung damage.² Risk can be impacted by multiple factors such as levels of Alpha-1, lifestyle and environment.

Testing for Alpha-1

Diagnosing Alpha-1 requires testing.² A genetic test can identify a specific gene mutation, and a blood test can measure both genotype and alpha-1 antitrypsin level.

Some risk factors² that indicate you should consider getting tested for Alpha-1 are:

• Lung manifestations such as obstructive lung disease (COPD), or asthma with airway obstruction that doesn't respond to treatment.
• Family history of lung or liver disease with no known cause.
• A family member with Alpha-1.

Getting an early diagnosis allows patients to work with their doctors to better understand their symptoms and take steps to help protect their lungs, including quitting smoking, maintaining updated vaccinations to avoid respiratory infections and avoiding jobs or places with harmful fumes and pollutants.²

"I look back and think, what if I'd been tested for Alpha-1 back when I first started struggling with my breathing," noted Daryl. "The diagnosis helped explain what my issues had been. And knowing there's changes I can make to my lifestyle gave me optimism that I could live with this condition."

The next endurance challenge

The more Daryl learned about his genetic condition, the better he understood how he could make an impact for his community. His new passion is educating others who might have Alpha-1 and spreading the word about the importance of screening.

"There comes a time when you take a negative and turn it into a positive," added Daryl. "After my diagnosis, I had a gift of knowledge, and I could educate and pass this along to people I cared about."

Learn more about Alpha-1 at RethinkAlpha1Protection.com.

________________________________________

[1] Alpha-1 antitrypsin deficiency. MedlinePlus Genetics website. https://medlineplus.gov/genetics/condition/alpha-1-antitrypsin-deficiency/. Accessed April 2026.

[2] Meseeha M, Attia M, Sankari A. Alpha 1 antitrypsin deficiency. PubMed. Published 2023. https://www.ncbi.nlm.nih.gov/books/NBK442030/. Accessed April 2026.

[3] Greulich T, Vogelmeier CF. Alpha-1-antitrypsin deficiency: increasing awareness and improving diagnosis. Ther Adv Respir Dis. 2016;10(1):72-84.

[4] James K. Stoller, MD, MS. Cleveland Clinic Journal of Medicine March 2026, 93 (3) 153-157; DOI: https://doi.org/10.3949/ccjm.93a.25103. https://www.ccjm.org/content/93/3/153#T1. Accessed June 2026.

[5] Alpha-1 Antitrypsin Deficiency Symptoms, Causes and Risk Factors. www.lung.org. https://www.lung.org/lung-health-diseases/lung-disease-lookup/alpha-1-antitrypsin-deficiency/symptoms-diagnosis. Accessed April 2026.

[6] Tanash HA, Piitulainen E. Liver disease in adults with severe alpha-1-antitrypsin deficiency. J Gastroenterol. 2019;54(6):541-548. doi:10.1007/s00535-019-01548-y.

• Members of the sandwich generation are often challenged with the cost and concerns of caring for two generations at the same time.
• Caring for someone with Alzheimer's disease or Parkinson's can bring stress, but caregiving also brings joy and connection with loved ones.
• Family caregivers need help from professional caregivers to understand the neurodegeneration and progressive nature of Alzheimer's, Parkinson's and other diseases, and to help prevent burnout.
• Comfort Keepers provides professional in-home caregiver services so adult daughters or sons have a trusted partner for family respite, allowing them to spend more quality time and make joyful memories with their parent.

By Sherri Snelling, gerontologist and Comfort Keepers spokesperson

Caregivers from the sandwich generation perform a delicate balancing act: simultaneously caring for children and older parents, along with other obligations such as work. While stretching your time, energy and emotional resources thin, you have little "me time" for self-care. The good news is, although caregiving can be disruptive, it is also one of the most powerful expressions of love. The key is finding ways to connect joyfully with aging parents, and being proactive in getting help so you can enjoy your time together.

In the 2026 National Day of Joy survey conducted by Talker Research on behalf of Comfort Keepers, 93% of aging adults say being cared for by an adult son or daughter has brought them closer together, and 96% of caregivers in the sandwich generation say family comes first. The strength of these familial bonds is clear, but that does not mean you do not need support as you try to meet the needs of your children, your parents and yourself.

These pressures become even more intense and complex when a parent is living with progressive, degenerative conditions like Alzheimer's disease or Parkinson's disease. Studies have found the intensity of dementia caregiving creates more stress, anxiety and depression. These caregivers also spend twice as long in their caregiving role: According to the Alzheimer's Association, dementia caregiving is an average of 9 years versus 4.5 years for other types of family caregiving, making it a marathon, not a sprint. During this marathon, professional help can support your physical and mental energy.

How to support your well-being while caring for an aging parent

Caring for yourself is one of the biggest challenges for family caregivers. The additional time needed to care for someone with dementia or a neurodegenerative disease like Alzheimer's or Parkinson's while maintaining work-life balance and raising children is very challenging. The sandwich generation dementia caregiver often ends up sacrificing their own social, emotional or physical health. In addition, the stigma of diseases affecting the brain can lead you to avoid social interactions and conversations, making you feel more alone.

This isolation means many adult children carry the caregiving burden alone, feeling they cannot or should not ask for help. Dementia care can largely involve physical and administrative tasks like tracking medical appointments, medication reminders and administration, managing insurance paperwork, home safety, getting groceries and prepping meals. Small moments of joy that really matter get lost: things like enjoying a meal together, looking at old photos or sharing interests like music, nature or crafts that create quality of life for the older parent and the adult daughter or son.

To help sandwich generation caregivers focus on what matters most, here are common myths around caregiving, and approaches that help families thrive.

Myth 1: If Mom or Dad is safe, everything is OK.

Reality: Quality of life matters. Caregiving is not just about physical tasks and safety, doctor appointments, fall prevention and personal care. Social and emotional health are equally important. Companionship, favorite routines and activities, conversation and sharing moments of joy help an older adult and the family caregiver feel connected and engaged.

Myth 2: I should be able to handle this alone.

Reality: Caregiver burnout is real, and creating your care team is critical. Many adult children assume care responsibilities gradually, until they are spending 20-40 hours a week on care tasks. This can lead to burnout and negatively impact your relationship with your parent. Professional caregivers, such as the in-home care specialists at Comfort Keepers, can become a part of your family's care team before a crisis happens. Professional help lets you take breaks to recharge and practice needed self-care, so you can be more focused on the emotional needs of your loved one.

Myth 3: I will get help when I really need it.

Reality: Waiting too long can lead to a crisis, but getting help before your parent's care reaches a crisis can make the caregiving journey easier for everyone. Progressive conditions such as Alzheimer's disease and Parkinson's can affect memory, communication, mobility, mood, personality, daily routines and activities including eating, getting dressed and bathing. Planning ahead gives families time for necessary conversations about long-term care, and to find the right professional caregiver, establish familiar routines and create a care plan that can evolve along with their parent's needs and family finances.

Myth 4: All visits must be productive.

Reality: Professional caregiving takes some everyday responsibilities off your shoulders, so time with your parent is not consumed by errands, household tasks and caregiving duties. By being "present," you enhance the emotional health of your parent and yourself. Sometimes the most important thing is simply being your parent's son or daughter.

How can I maintain my relationship with my aging parent?

Caring for a parent with dementia, Alzheimer's and Parkinson's is emotionally difficult for family caregivers. Alzheimer's adults may forget your name or who you are, and they may become combative and physically lash out. Someone with Parkinson's may have frightening hallucinations and nightmares. All of this occurs in addition to declining physical and cognitive abilities.

The Comfort Keepers survey reveals that daily joy for aging adults is rooted in the connection found during everyday life moments: sitting outside, enjoying morning coffee or engaging in meaningful hobbies such as reading, gardening, crafts and music. These moments foster consistency, independence and a sense of purpose. They also give family caregivers moments of calm in the midst of chaos.

For someone living with Alzheimer's or Parkinson's, these activities may need to be adapted as their condition progresses. A familiar song from their past, simplified gardening activity, short walk or time spent looking through family photographs can offer connection and comfort. The goal is not necessarily doing things exactly as before, but to find meaningful ways to meet the person where they are now.

For adult children, joy is found in everyday connection with aging parents. In the survey, nearly 3 in 4 (72%) say simple conversations bring the most joy, followed by sharing meals (68%) and helping provide care for them (67%). A whopping 95% of adult children agree older adults play an important role in creating joy within their families.

Where to begin finding a caregiver

Comfort Keepers understands the challenges families face when caring for a loved one with Alzheimer's disease or Parkinson's, particularly as their needs change. Specially trained caregivers can help them continue living safely and meaningfully at home through personalized care, familiar routines, companionship and activities tailored to their interests and abilities. Comfort Keepers can also educate families about their changing needs and provide support that engages them physically, mentally and emotionally.

Comfort Keepers provides in-home services including:

• Personal care
• Companionship
• Medication reminders
• Family respite care
• Comfort360™: A Complete Circle of Care

There is no need to choose between being a good parent, partner, employee and caregiver as you juggle roles. Professional caregiving help from Comfort Keepers means better quality of life for your parent and for yourself, helping you remain your parent's daughter or son first.

Visit ComfortKeepers.com to learn more.

Here's what you need to know about this year's outage season, and why taking advantage of Amazon's Prime Big Deal Days, Oct. 6-7, can help you find the right backup solution.

Outages are already common this year

According to Talker Research for Sunrun, two out of three homeowners have already experienced a power outage in 2026, even before fall and winter storm season has started. To prepare your household before you suddenly have no lights, refrigeration, heating or internet, start with a smaller option that can be expanded later.

For example, consider one of these options from Jackery, a global leader of home backup, innovative solar generators and green off-grid energy solutions:

• HomePower 1000 Plus V2 is a great choice if you're one of the 41% with no backup power. This 1024Wh unit is expandable up to 11kWh with add-on extension batteries, so a household can start small and grow coverage as needed. The 1800W rated output (3600W surge) runs roughly 80% of standard household appliances, keeping your refrigerator going up to 19 hours, or a space heater through a freezing night. The built-in uninterruptible power supply (UPS) switches to battery in 10 milliseconds or less, keeping routers and desktops online without rebooting.
  
  
• HomePower 2000 Plus V2 is a plug-and-play option that's expandable from 2048Wh up to 12kWh with add-on extension batteries with no rewiring or electrician required. It has a 2400W rated output (4800W peak surge), and the baseline unit alone can carry a typical refrigerator to keep your food cold for 48 hours.

Today's outages last longer

According to the U.S. Energy Information Administration, U.S. customers averaged 11 hours without power in 2024, nearly twice the prior decade's average, with major storms driving 80% of those hours. That's why it's more crucial than ever to plan for outages lasting anywhere from several hours to several days.

Live in a storm-prone region and want to be prepared for multi-day outages? One of these backup solutions could work for your household:

• HomePower 3600 Plus offers a 3600W output and 3584Wh capacity in a unit that rolls easily from garage to living room. The unit can connect to the home through a Manual Transfer Switch and expands up to 21kWh to carry essential circuits through a multi-day outage.
  
  
• Explorer 5000 Plus is ideal for larger homes. It pairs with a Smart Transfer Switch to take over essential circuits automatically. The unit has a 7200W rated output and modular expansion up to a potential 60kWh to cover your HVAC system, refrigeration and well pumps, all at once.

This winter may be unusual

The NOAA Climate Prediction Center forecasts a greater than 90% chance of a very strong "Super El Nino" this fall and winter, typically bringing wetter, cooler conditions all the way from central California to Florida and up the East Coast. Prepare for that by getting backup power so you're ready before the first storm hits.

• HomePower 3000 is a compact, easy-to-tuck-away solution that can prepare your home thanks to 3072Wh with 3600W output to keep the fridge, Wi-Fi, fans and lights running for a day or two. Its ZeroDrain™ technology means it sits ready at nearly full charge for up to 12 months, and an approximately 20-millisecond automatic switchover picks up the moment the grid drops.

What people miss most is predictability

According to Talker Research, homeowners say the biggest disruptions during outages are losing heating/cooling (57%), food spoilage (48%) and losing internet/cell service (44%). You can keep the heat on, food cold and Wi-Fi connection going with some planning: Choose a backup power solution now, so you'll have peace of mind when the power goes out.

5 things to check before you add to your cart

Shopping for home power backup? Here are top questions to ask so you can click "Place Your Order" with confidence during Amazon's Prime Big Deal Days.

1. What must stay on? Do you need backup for your fridge, heat, Wi-Fi, medical devices and/or other appliances? Knowing your must-haves helps you make a smart decision.

2. How long do you need power? Look for watt hours (Wh), which indicates how long power can last, and watts (W), which means how much power you need all at once.

3. Can your power grow with add-on batteries? You may want a unit that's expandable in case you need more backup power.

4. Does it switch over instantly? Uninterruptible power supply, or UPS, protects electronics from power disturbances by switching to internal battery power when needed.

5. How long does the battery last? Look for LiFePO4/LFP cells, which are rechargeable lithium-ion batteries that are more stable and last longer.

Learn more about home backup power solutions at Jackery.com.

Every year, changing leaves means new routines. Swimsuits are traded for jackets, new backpacks and fresh notebooks are added to the cart — and for millions of families, the checklist includes extra supplies to help children manage eczema symptoms.

Eczema (atopic dermatitis) affects approximately 9.6 million children and 16.5 million adults in the United States. More than dry skin, eczema is a chronic inflammatory skin condition that causes red, intensely itchy rashes that can appear anywhere on the skin.

It's a reality that actress and mom Tori Spelling knows firsthand. Tori lives with eczema herself and is also a caregiver to her daughter Stella (now 18, pictured as a child above), who has had eczema since she was a toddler.

"As a mom of five, our routines don't stop for eczema — carpool, homework, practice, all of it keeps moving," said Tori, mother, actress, best-selling author, executive producer, and successful podcast host. "I know how hard a flare can be, because I've lived it. And watching Stella go through it as a little girl, I felt helpless because nothing we tried seemed to calm her skin."

Like many families, Tori cycled through countless creams and home remedies to try to help Stella with her symptoms. Since atopic dermatitis is a lifelong condition, Tori wanted to find a treatment option that was steroid-free and could be used long-term.

"It was important to me to find a treatment that worked with our daily routine," Tori said. "When our dermatologist recommended ZORYVE^® (roflumilast) cream 0.15%, it changed the way we manage our eczema. ZORYVE has helped clear our skin and relieve the itch."

A steroid-free treatment option

ZORYVE cream 0.15% is indicated for the treatment of mild to moderate eczema in adults and children 6 years of age and older. In two clinical trials of over 1,300 people with mild to moderate atopic dermatitis, ZORYVE rapidly improved eczema symptoms such as redness, itching, and rash with once-daily treatment — with nearly a third (31% of the 884 people) achieving clear or almost clear skin at 4 weeks with ZORYVE cream compared to 15% of the 453 people using inactive cream. 32% of 542 people using ZORYVE cream experienced itch relief in 4 weeks vs 17% of 271 people using inactive cream.

For younger children, ZORYVE cream 0.05% is FDA-approved to treat mild to moderate eczema from age 2 to 5, and can be used for any duration, anywhere on the skin. In clinical trials of 652 children, ZORYVE cream 0.05% provided rapid and significant clearance of eczema, with 25% of 437 children using ZORYVE achieving clear or almost clear skin at 4 weeks with ZORYVE cream compared to 11% of 215 children using inactive cream. Additional results, 35% of the 347 children using ZORYVE cream experienced a reduction in itch in 4 weeks, compared to 18% of 160 children using inactive cream as reported by the caregiver.* It is important to note that individual results may vary and it is important to speak to your healthcare provider.

"Eczema is a chronic condition, so patients need treatments they can rely on over the long term," said Dr. Adam Friedman, professor and chair of dermatology at the George Washington University School of Medicine and Health Sciences. "ZORYVE is a once-daily topical treatment for atopic dermatitis formulated without a steroid and without known sensitizers or irritants that can further disrupt the skin barrier. The cream itself has moisturizing properties and it's non-greasy. What's encouraging is how far we've come; just a decade ago, options were limited and we often used medications that were never intended for this extremely common condition. Today, updated American Academy of Dermatology guidelines recognize there are multiple treatment options available, which means we can personalize the decision to the patient. My advice for the new school year is don't dismiss eczema as 'just dry skin,' as just like the translation of its name, it will progressively 'boil up' if not addressed. Talk to a dermatologist about a plan that works for your child."

Tori and Stella have partnered with Arcutis Biotherapeutics on the Free to Be Me awareness campaign to help raise awareness and reduce the stigma around inflammatory skin conditions like eczema.

"Managing eczema is a journey that too many people go on alone," Tori said. "If sharing our story encourages even one family to talk to their doctor — it's worth it."

INDICATIONS AND IMPORTANT SAFETY INFORMATION

Approved Uses
ZORYVE cream 0.15% is a prescription medicine used on the skin (topical) to treat mild to moderate eczema (atopic dermatitis) in adults and children 6 years of age and older.

It is not known if ZORYVE cream 0.15% is safe and effective in children with mild to moderate eczema (atopic dermatitis) younger than 6 years of age.

ZORYVE cream 0.05% is a prescription medicine used on the skin (topical) to treat mild to moderate eczema (atopic dermatitis) in children 2 to 5 years of age.

It is not known if ZORYVE cream 0.05% is safe and effective in children with mild to moderate eczema (atopic dermatitis) younger than 2 years of age and older than 6 years of age.

IMPORTANT SAFETY INFORMATION

ZORYVE is for use on the skin (topical use) only. Do not use ZORYVE in your eyes, mouth, or vagina. Do not use ZORYVE if you have certain liver problems.

Before using ZORYVE, tell your healthcare provider about all of your medical conditions, including if you:

• have liver problems.
• are pregnant or plan to become pregnant. It is not known if ZORYVE will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if ZORYVE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with ZORYVE. Breastfeeding women using ZORYVE should use it on the smallest area of the skin and for the shortest time needed. Do not apply ZORYVE directly to the nipple or areola to avoid contact with your baby. Avoid direct skin contact of treated areas with your baby if ZORYVE is applied to your chest.

Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of ZORYVE cream 0.15% in adults and children 6 years of age and older treated for atopic dermatitis include:

• headache
• nausea
• application site pain
• diarrhea
• vomiting

The most common side effects of ZORYVE cream 0.05% in children 2 to 5 years of age treated for atopic dermatitis include:

• upper respiratory tract infections
• diarrhea
• vomiting
• stuffy or runny nose
• red or swollen eyes (like "pink eye")
• headache

These are not all of the possible side effects of ZORYVE. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Patient Information for ZORYVE.

Families don't have to navigate eczema alone. To learn more about eczema and ZORYVE, or to connect with a healthcare provider through the virtual health platform, visit ZORYVE.com.

Photos courtesy of Tori Spelling, a mom, actress, and paid spokesperson for ZORYVE.

*Itch levels in clinical trials of ZORYVE cream 0.05% were tracked and reported by caregivers of children daily. This technique may need more testing to confirm its accuracy in children under 12 years old. Results may vary.

© 2026 Arcutis Biotherapeutics, Inc. All rights reserved.
US-CRP-151-2-00002 10/26

On Jan. 9, 2020, her father, Dr. Cesar Termulo, a pediatrician in Dallas, Texas, received a call from her school that she was feeling sick. Termulo — who suspected she could have contracted the flu — quickly brought her to his office, where she tested positive for influenza B, was given antivirals, and went home to rest and recover.

"Reese wasn't as sick as many of my other patients who had influenza B," said Termulo. "She seemed to be improving — no fever, and she didn't show signs of pneumonia or other serious flu complications."

The next morning, Reese felt ready to go to school, but her father insisted she stay home. Before he left for work, Termulo used his stethoscope to listen to his daughter's heart and lungs so that he could check for serious complications and concluded she was on the mend.

"The last thing I ever said to Reese was that I thought she would get better," said Termulo.

No one could have suspected that Reese's symptoms would rapidly progress, and her condition would take a turn for the worse. Later that morning, Reese's mother found her upstairs, passed out, and she had stopped breathing. The flu virus had quickly attacked her lungs, and she eventually became septic. Reese passed away less than 24 hours after her diagnosis.

Serious flu complications

Influenza (or flu) is a contagious respiratory illness caused by flu viruses that infect the nose, throat and sometimes the lungs.¹ People can begin spreading the flu to others one day before symptoms start and up to a week after symptoms appear — and some, especially young children, might be contagious to others for even longer.¹

The flu can impact every person differently. Symptoms can appear suddenly and can include fever (or feeling feverish/chills), cough, sore throat, runny or stuffy nose, muscle or body aches, headaches and fatigue.²

While most people who get the flu will recover within a few days to less than two weeks, some may develop complications like pneumonia and even death.²

The 2025-2026 flu season followed one of the most severe flu seasons in recent U.S. history, with record-breaking pediatric deaths and overwhelming levels of illness and hospitalization.³ In fact, from Oct. 1, 2025, through May 9, 2026, the Centers for Disease Control and Prevention (CDC) estimated that there were at least 32 million illnesses, 390,000 hospitalizations and 24,000 deaths from the flu in the U.S.⁴

"The harsh reality is that anyone can get sick from the flu — even people who are or feel healthy — and serious problems related to flu can happen at any age," said Dr. Luis Romano, GSK's US Medical and Clinical Affairs Lead for Flu Vaccines. "That said, some people are at higher risk of developing serious flu-related complications if they get sick."

Groups at higher risk of serious flu-related symptoms include¹:

• People 65 years and older
• People with certain chronic health conditions (such as asthma, diabetes or heart disease)
• Pregnant women
• Young children

The flu does not affect all communities equally, and the 2025-2026 season once again exposed deep and persistent disparities in flu-related outcomes among racial and ethnic minority groups.⁵ According to the CDC, Black and Hispanic communities consistently experienced higher rates of flu-related complications and death, often due to lower vaccination rates and delayed access to care.⁶

Why you should speak to your provider about annual flu vaccination

The flu is a serious illness and should be taken seriously. The best way to help protect yourself and your loved ones from the flu every season is to vaccinate everyone 6 months of age and older annually.³

"Decades of data confirm that flu vaccines have an excellent safety record," said Romano. "In fact, hundreds of millions of Americans have received flu vaccines over the past 50 years, and ongoing monitoring consistently reinforces their strong safety profile."⁷

Since Reese's passing, Termulo and his family have made it their mission to educate families on the potential dangers of the flu and urge people to get vaccinated against the flu every year.

Now is a good time to think about flu vaccination

Fall can be a busy season for many people, but it's vital to make time to get your flu shot. The CDC recommends that most people receive their flu vaccine in September or October, ideally by the end of October.⁸ The good news is that getting a flu shot is typically quick and convenient.

If you already have a yearly wellness visit scheduled, ask your primary care provider about receiving your flu shot during your visit. You can also get a flu shot in pharmacies, urgent care clinics, college health centers and even some schools or workplaces.⁹ Some locations like your local pharmacy may accept walk-ins, so you can help protect yourself and your loved ones from the flu with minimal time commitment.

To learn more about the flu and flu prevention, visit CDC.gov/Flu.

"The flu can disrupt your life and your family's lives," said Termulo. "Losing my daughter is a heartbreaking reminder that the flu can have devastating consequences. As both a father and a physician, I hope our family's experience encourages others to recognize the seriousness of the flu and the profound impact it can have on families."

Sources

1. About Influenza (Flu). Centers for Disease Control and Prevention. Reviewed Feb. 26, 2026. Accessed July 17, 2026. https://www.cdc.gov/flu/about/index.html

2. Symptoms and Signs of Flu. Centers for Disease Control and Prevention. Reviewed Aug. 26, 2024. Accessed July 17, 2026. https://www.cdc.gov/flu/signs-symptoms/index.html

3. Influenza Activity in the United States During the 2024-25 Season and Composition of the 2025-26 Influenza Vaccine. Centers for Disease Control and Prevention. Reviewed Sept. 26, 2025. Accessed July 17, 2026. https://www.cdc.gov/flu/whats-new/2025-2026-influenza-activity.html

4. Weekly U.S. Influenza Surveillance Report: Key Updates for Week 18, Ending May 9, 2026. Centers for Disease Control and Prevention. Published May 15, 2026. Accessed July 17, 2026. https://www.cdc.gov/fluview/surveillance/2026-week-18.html

5. Weekly U.S. Influenza Surveillance Report: Key Updates for Week 25, Ending June 27, 2026. Centers for Disease Control and Prevention. Published July 6, 2026. Accessed July 17, 2026. CDC FluView Week 25

6. Flu and Healthy Lives for All. Centers for Disease Control and Prevention. Published Jan. 17, 2025. Accessed July 17, 2026. https://www.cdc.gov/flu/healthy-living/index.html

7. Influenza (Flu) Vaccine Safety. Centers for Disease Control and Prevention. Reviewed October 2023. Accessed July 17, 2026. https://www.cdc.gov/vaccine-safety/vaccines/flu.html

8. Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness—United States, September 2025-February 2026. MMWR Morb Mortal Wkly Rep. 2026;75(9):116-123. Published March 6, 2026. Accessed August 6, 2026.

9. Where to Find Vaccines. Centers for Disease Control and Prevention. Published July 10, 2024. Accessed July 17, 2026. https://www.cdc.gov/vaccines-adults/recommended-vaccines/vaccine-planning.html

• Homeowners are seeking to make their homes more efficient, including indoor air quality solutions.
• Improving a home's IAQ typically requires homeowners to install multiple products that don't work together.
• Panasonic OASYS^® solves this problem by continuously bringing in fresh, filtered outdoor air that is balanced with indoor air to improve IAQ, temperature and humidity, creating a healthier living environment.

The modern home has technology layered in practically every corner. Whether it's a smart thermostat, voice assistants, connected security, EV chargers or app-controlled appliances, homeowners are looking to make home life easier and — in some cases — healthier.

Take indoor air quality (IAQ), for example. According to the U.S. Environmental Protection Agency (EPA), Americans spend on average about 90% of their time indoors, where the concentration of some pollutants is often two to five times higher than typical outdoor air. Although you can't see them, these air pollutants can have very real visible effects on your health and have been associated with:

• Irritation of the eyes, nose and throat.
• Headaches, dizziness and fatigue.
• Respiratory diseases, heart disease and cancer.

There are numerous smart devices on the market to improve IAQ, including monitors, purifiers, dehumidifiers and more. However, these separate IAQ technologies don't work together, requiring homeowners to monitor and adjust the settings themselves.

Seeing the need for connected and efficient IAQ technology that works in concert, Panasonic created OASYS^®, a whole-home air quality management solution that aligns comfort, air quality and energy management, providing homeowners with a true set-it-and-forget-it IAQ system.

Designing IAQ tech with whole-home integration from the start

Panasonic OASYS^® creates a house that breathes as intentionally as it was designed. The energy-efficient system manages indoor air quality, temperature and humidity without homeowner intervention. The result? Cleaner air, balanced humidity, fewer indoor allergens and pollutants, and consistent temperature control throughout the house from the moment you walk in.

This isn't Panasonic's first foray into IAQ management. The brand's bathroom exhaust fans and energy recovery ventilators (ERVs) have helped homeowners across the country breathe cleaner indoor air. The addition of OASYS^® completes this family of IAQ solutions.

So, how exactly does OASYS^® work to improve IAQ? It all begins with its fresh-air-first approach.

Improving ventilation with outdoor air is one of the fundamental strategies for reducing concentrations of indoor air pollutants. However, most home heating and cooling systems do not mechanically bring in fresh air. By flipping the traditional HVAC logic, OASYS^® provides homeowners with balanced airflow to every room, including hard-to-reach areas, supporting the consistent comfort and well-being of families in their home environment.

When Olivia was one and a half, she was saying simple words that many toddlers typically learn first, but then her parents noticed something alarming — suddenly, those words had disappeared.

At the same time, Olivia's physical development started to change. She stopped climbing on furniture and playground equipment. Her muscle tone seemed weaker. She began struggling to grasp toys and other objects and had difficulty with tasks that had once come naturally.

For Jeff and his wife, Peggy, these changes were impossible to ignore and shaped nearly every aspect of Olivia's life and their family's journey. After a series of evaluations and genetic testing, they received an answer they never expected: Olivia had Rett syndrome.[1] She was two and a half years old.

This is Jeff, Peggy and Olivia's story:

Olivia lives with Rett syndrome, a rare, genetic neurodevelopmental disorder that affects approximately 1 in 10,000 girls in the U.S. (although less common, the disorder can also occur in boys).[2],[3] Children with Rett syndrome can lose previously acquired skills and experience challenges with communication, motor function and hand use.[4] Tasks that many children perform without thinking can become difficult, from communicating wants and needs to carrying objects and participating in everyday activities.

Like many parents receiving a rare disease diagnosis, Jeff and Peggy were overwhelmed. They immersed themselves in learning everything they could about the condition, connecting with specialists, joining the Rett syndrome community and seeking advice from other families who understood what they were experiencing.

"We needed all the help we could get," Jeff recalls.

Treating Rett syndrome

Over the years, Olivia's care has included occupational, speech and physical therapies, along with equine and aquatic therapy. The family also works closely with specialists and regularly visits a Rett Center of Excellence.[5]

Regardless of the challenges, Jeff and Peggy remained focused on helping Olivia participate as fully as possible in family life.

In 2023, Olivia's neurologist prescribed DAYBUE^® (trofinetide), the first and only drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of Rett syndrome in adults and pediatric patients two years of age and older. Following discussions with her care team and weighing the potential side effects (see below for Important Safety Information), Jeff and Peggy decided it was worth trying.

"There are a lot of things that contribute to Olivia's progress and development," Jeff says. "DAYBUE has been one of the key parts of that journey."

Since starting treatment, and complemented by a broader care plan and therapies, Jeff says he has observed meaningful improvements in Olivia. Some of the most impactful changes involve how Olivia uses her eye-gaze to engage with the people around her.

"She seems to know people, which makes her feel more comfortable connecting and interacting with them," Jeff says.

Olivia uses an eye-gaze device at school and during speech therapy to help express her wants and needs. Some days she embraces it. Other days, Jeff notes, she would rather knock it over and move on to something else. At home, the family uses picture cards and simple choices to help Olivia express herself.

Jeff says Olivia's vocalizations have also become more distinct. The family can often tell based on the sounds Olivia makes whether she is hungry, tired or eager to jump into the pool — something that was difficult for her in the past.

He has also noticed changes in how Olivia participates in some of her favorite activities. During aquatic therapy, she eagerly reaches for and holds on to her favorite mermaid doll. In equine therapy, she has been able to hold the handle on the saddle at times with her teacher's assistance, and the duration of her grip has increased. "She has even learned to follow her teacher's instructions for keeping both hands on the handle and grabs the reins at various points during the lesson," Jeff says.

For many families, these may seem like small moments. For Jeff, they are very meaningful.

Despite the improvements he has noticed in Olivia, Jeff says she still has days that are more difficult than others, and they sometimes face behavioral challenges. However, the changes in Olivia's mood have made a big difference for the family. Before DAYBUE, mornings could be especially challenging, often beginning with unexplained irritability and fussiness. Now, Jeff says Olivia is more pleasant and playful, making mornings calmer and easier to navigate.

"We noticed Olivia seems happier, something that we haven't seen before, and that has been amazing for us. We're able to spend more time together as a family and create new memories," said Jeff.

Experience with DAYBUE^® STIX

More recently, Olivia began using DAYBUE^® STIX, which was approved by the FDA in December 2025. It is bioequivalent to the original DAYBUE oral solution, so it is expected to deliver the same efficacy and safety profile, while offering children and adults living with Rett syndrome flexibility and choice regarding the dose volume and taste of their DAYBUE treatment.[6]

"As clinicians, we work closely with patients and their families to identify treatment approaches that align with their individual circumstances and preferences. Having formulation options available allows those decisions to be tailored to each patient," says Steve Skinner, MD, President and CEO of the Greenwood Genetic Center, Greenwood, SC, and Director of the Rett Center of Excellence in South Carolina.*

"Olivia doesn't like taking medicine," Jeff says. "Before, it could take us 10 minutes because she would store it in her mouth or sometimes spit it out."

Because DAYBUE STIX can be dissolved in cold to room temperature water or water-based beverages such as juice, tea, lemonade, limeade or liquid hydration, the family experimented with different options before finding one Olivia enjoys.[6]

"Peach mango juice seems to be the winner right now," Jeff says with a laugh.

The family also appreciates the portability of the packets. Since they do not require refrigeration, Jeff says they are easier to bring along to activities and may make future travel simpler.[6]

Still, the moments Jeff remembers most aren't the ones found in a medical chart. One morning, he came downstairs expecting the usual start to the day. Instead, Olivia looked at him and quietly said a word he had waited years to hear. "Dada." For many parents, the moment might seem small. For Jeff, it was unforgettable.

And for families living with Rett syndrome, it is often those moments that mean everything.

Olivia's experience with DAYBUE and DAYBUE STIX is unique to her and may not be the same as yours.

Always speak with a healthcare provider to learn what to expect when starting DAYBUE or DAYBUE STIX, including side effects. See below for Important Safety Information related to DAYBUE.

DAYBUE^® and DAYBUE^® STIX (trofinetide) Indication and Important Safety Information

What is DAYBUE or DAYBUE STIX?

DAYBUE or DAYBUE STIX are prescription medicines used to treat Rett syndrome in adults and children 2 years of age and older. It is not known if DAYBUE or DAYBUE STIX is safe and effective in children under 2 years of age.

What are the possible side effects of DAYBUE or DAYBUE STIX?

• Diarrhea: Diarrhea is a common side effect of DAYBUE or DAYBUE STIX that can sometimes be severe. Diarrhea may cause you to lose too much water from your body (dehydration). Before starting treatment with DAYBUE or DAYBUE STIX, stop taking laxatives. Tell your healthcare provider if you have diarrhea while taking DAYBUE or DAYBUE STIX. Your healthcare provider may ask you to increase the amount you drink or take antidiarrheal medicine as needed.
• Vomiting: Vomiting is a common side effect of DAYBUE or DAYBUE STIX. Sometimes vomit can get into your lungs (aspiration), which could cause an infection (aspiration pneumonia). Tell your healthcare provider if you have severe vomiting or if vomiting happens often.
• Weight loss: DAYBUE or DAYBUE STIX can cause weight loss. Tell your healthcare provider if you notice you are losing weight at any time during treatment with DAYBUE or DAYBUE STIX.
• The most common side effects of DAYBUE or DAYBUE STIX include diarrhea and vomiting. Other side effects include fever, seizure, anxiety, decreased appetite, tiredness, and the common cold. These are not all the possible side effects of DAYBUE or DAYBUE STIX. Tell your healthcare provider if you have any side effects that bother you or do not go away.

What should I tell my healthcare provider before taking DAYBUE or DAYBUE STIX?

Before taking DAYBUE or DAYBUE STIX, tell your healthcare provider about all of your medical conditions, including if you:

• have kidney problems.
• are pregnant or plan to become pregnant. It is not known if DAYBUE or DAYBUE STIX will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if DAYBUE or DAYBUE STIX passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby while taking DAYBUE or DAYBUE STIX.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking DAYBUE or DAYBUE STIX with certain medicines may affect how the other medicines work and can cause serious side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088. You can also call Acadia Pharmaceuticals Inc. at 1-844-4ACADIA (1-844-422-2342).

DAYBUE is available as an oral solution (200 mg/mL).

DAYBUE STIX for oral solution powder is available in 5,000 mg, 6,000 mg, and 8,000 mg packets.

The risk information provided here is not comprehensive. To learn more, talk with your healthcare provider and read the full Prescribing Information, including Patient Information, also available at DAYBUE.com.

Note:

Jeff is a paid Acadia consultant who has been compensated for sharing his story of Olivia's real patient journey with Rett syndrome. The family's experience may not be the same as yours. Because everyone with Rett syndrome is unique — with a unique set of symptoms — the response to DAYBUE may be different for each individual.

*Dr. Steve Skinner is not Olivia's treating provider.

[1] Neul JL, Kaufmann WE, Glaze DG, et al. Rett Syndrome: revised diagnostic criteria and nomenclature. Ann Neurol. 2010;68(6):944-950.

[2] May D, Kponee-Shovein K, Mahendran M, et al. Epidemiology and patient journey of Rett syndrome in the United States: a real-world evidence study. BMC Neurol. 2023;23(1):141

[3] Fu C, Armstrong D, Marsh E, et al. Consensus guidelines on managing Rett Syndrome across the lifespan. BMJ Paediatr Open.

[4] Kyle SM, Vashi N, Justice MJ. Rett Syndrome: a neurological disorder with metabolic components. Open Biol. 2018; 8:170216.

[5] International Rett Syndrome Foundation. IRSF Center of Excellence Network.

[6] Acadia Pharmaceuticals Inc., (2025, December 12). Acadia Pharmaceuticals Announces FDA Approval of DAYBUE^® STIX (trofinetide) for Oral Solution, a New Powder Formulation of Trofinetide for the Treatment of Rett Syndrome

DAY-US-0876 9/2026

Understanding your dog's oral microbiome can help pet parents better understand the importance of daily dental care and keeping plaque and tartar under control.

What is the canine oral microbiome?

Not all bacteria are harmful. Your dog's mouth is home to hundreds of bacterial species and other microorganisms that form a living ecosystem, known as the oral microbiome.

"A healthy oral microbiome is about balance. When that balance is maintained, different microorganisms can coexist in the oral environment. When that balance changes, certain bacteria can become more prevalent and may contribute to oral health problems," says Sara Ahlström, Global Marketing Manager at Swedencare.

This balance is one reason why the oral microbiome and dental health are closely connected.

How are plaque and tartar connected to the microbiome?

Plaque isn't random or unavoidable. This thin biofilm that sticks to your dog's teeth and gums is actually a microbial community that builds up every day.

Without regular oral care, plaque can eventually harden into tartar. Unlike plaque, tartar cannot simply be brushed away and may require professional veterinary scaling to remove. Controlling plaque before it builds up and mineralizes is an important part of maintaining good dental health.

What happens when plaque and tartar take over?

Plaque and tartar buildup can contribute to bad breath, gum inflammation and periodontal disease. Advanced periodontal disease has also been associated with health effects beyond the mouth. A study published in the Journal of the American Veterinary Medical Association, for example, found an association between advanced periodontal disease and heart disease in dogs.

This is why dental care is about more than keeping your dog's breath fresh. Oral health is an important part of your dog's overall health, which is why preventing and controlling plaque and tartar matters.

How can I safely prevent and control plaque?

Regular veterinary dental checkups and a consistent home dental care routine are important for keeping plaque under control. Depending on your dog, this can include brushing their teeth with a soft toothbrush and dog-safe toothpaste, providing appropriate dental chews or toys, and using dental supplements as part of their daily routine.

Next, make sure to build a home dental care routine for your dog and stick with it.

The key is consistency. Plaque starts to build up again after it is removed, so regular oral care is important for maintaining your dog's dental health.

What kind of dental supplements should I give my dog?

With so many dental supplements available, it can be difficult to know which option is right for your dog. Look for products that are backed by research and clinical studies, with clearly defined benefits for your dog's dental health.

"Pet parents have many options when it comes to supporting their dog's dental health, so it's important to choose a product and format that fits easily into their daily routine and has evidence to support its specific benefits," says Sara Ahlström, Global Marketing Manager at Swedencare.

A great choice that is convenient for pet parents and delicious for their pups is the ProDen PlaqueOff^® line of dental products. Each product is formulated with A.N. ProDen^®, a 100% natural kelp ingredient that has been clinically studied. Studies have demonstrated significant reductions in plaque and tartar, as well as improvements in bad breath.

Try giving your furry friend a daily treat of ProDen PlaqueOff^® Crunchy Dental Bites for Dogs, a convenient dental supplement that they'll love to take every day. If your pup loves to chew, lean into their natural inclination and offer them a ProDen PlaqueOff^® Dental Care Bone. This dental treat pulls double duty by mechanically reducing plaque while keeping them deliciously engaged.

If you have an older canine who has trouble chewing, don't worry. You can still care for their dental hygiene by giving them a tasty treat with ProDen PlaqueOff^® Soft Chews or by mixing an oral health Powder for Dogs. These oral supplements offer convenient options for supporting your dog's daily dental care routine and helping to control plaque and tartar.

Taking care of your dog's dental health, preventing plaque and tartar, and maintaining a healthy oral environment doesn't have to be difficult. To learn more about how you can take care of your dog's dental and overall health, visit Swedencare.com/en.

What is myopia and why is it becoming more common?

Myopia, commonly called nearsightedness, is a condition in which objects further away appear blurry, while close-up objects are usually clear. It often begins during childhood and may continue to progress or worsen as a child grows, usually stabilizing in late teens or early adulthood. Parents think myopia means blurry vision because the prescription is increasing but it's more than that — it's not a benign condition. Myopia leads to the eyeball growing too fast and too long — leading to the abnormal stretching of the eye and potentially other eye health complications in future. Correcting vision alone does not address the excessive eye growth in myopia.

Myopia is becoming increasingly common. In the United States, its prevalence has increased from 26% to 42% between 1972 to 2002,¹ and worldwide estimates suggest that nearly half of the population may have myopia by 2050.²

The increase in school-age myopia we are seeing today is predominantly driven by lifestyle factors while genetics can predispose a child.³ Children with parents who have myopia are also at greater risk of developing myopia.³ Studies show that children should spend at least 2 hours outside daily and it is the lack of time outdoors that is a major risk for myopia development as well as prolonged near work.^3,4 Children today often spend more time doing close-up activities and less time outdoors.^3,4. The role of digital devices in myopia is not clear but it is good to establish good visual hygiene and limit screen time, according to the screen guidelines set by the American Academy of Pediatrics.⁷

The good news is that there are steps families can take.

Why "just knowing" isn't the finish line

Recognizing the signs of myopia is important, but awareness alone doesn't protect a child's vision. The next step is making sure vision concerns lead to appropriate eye care. Vision screenings at school or at the pediatrician's office can identify some children who may have a vision problem, but a screening is not the same thing as a complete evaluation of a child's eyes and vision.

Keep in mind that children may assume their vision is normal because it is the only vision they know. Through comprehensive eye examinations, eye care professionals can identify myopia and assess children who may be at increased risk of developing it as well as other childhood conditions. Factors such as family history, near-work habits and time spent outdoors can help provide a more complete picture of a child's risk.^3,4 The doctor can also help parents recognize vision-related signs that might otherwise be attributed to behavior, attention or school performance.

What early intervention actually looks like

For generations, the usual response to childhood myopia was straightforward: When a child's vision became blurrier, the prescription was increased. But today, the conversation has changed. Traditional single-vision glasses and contact lenses correct blurry vision, but myopia management is intended to do something more: slow the rate at which myopia progresses.^3,5

Myopia should be managed as soon as it is detected given that the fastest rate of increase tends to be at the earlier ages and thus is the critical time to intervene.³ Today there are a number of options available to manage myopia: there is an FDA-authorized myopia management spectacle lens called Essilor^® Stellest^® lenses⁶ and an FDA approved contact lens called Coopervision^® Misight^® 1 Day.³ These correct myopia while slowing its progression at the same time. In addition, there are also overnight reshaping lenses.³ Your eye care professional will determine the appropriate treatment for your child based on their clinical and lifestyle factors as well as age.

Since Essilor^® Stellest^® Lenses were approved by the FDA in September 2025, we have trained more than 30,000 eye care professionals on myopia management and the role of Essilor^® Stellest^® to help address this growing public health concern. Essilor^® Stellest^® Lenses were authorized by the FDA with language recognizing myopia progression as a disease, helping elevate the conversation beyond simple vision correction toward proactive disease management.

Small daily habits can make a difference

Healthy visual habits can start today. Spend more time outdoors. Research has consistently demonstrated that increased outdoor time delays the development of myopia in children.^3,4

• Make outdoor play and activities part of the family's regular routine.
• Give the eyes regular breaks. Long periods of uninterrupted close-up work should be broken up.⁷
• Be thoughtful about screens and other near work. Screens are part of children's lives, and the goal isn't necessarily to eliminate them. Instead, avoid unnecessarily prolonged recreational screen time, encourage breaks and remember that books, homework, phones, tablets and other close-up activities all contribute to time spent focusing at near.^3,4
• Don't hold things too close. Encourage children to maintain a comfortable working distance rather than bringing books, phones or tablets very close to their face. Very close working distances and long periods of continuous near work have been associated with myopia.^3,4

Most importantly, these habits should complement — not replace — professional eye care or prescribed myopia management.

Why does acting now matter?

Myopia often progresses throughout childhood. That means the changes that occur from year to year can add up. Higher levels of myopia later in life are associated with a greater risk of several eye diseases and that risk increases as the amount of myopia increases.^5,8 That's one reason the goal today isn't simply to help a child see clearly with the next pair of glasses. When appropriate, it is also to slow the progression of myopia while the eyes are still growing.

There is no single approach that's right for every child. But there is an important first step for every parent who has concerns: Don't just watch and wait. Start the conversation. Schedule an eye examination with an eye care professional.

A simple parent action checklist

• Watch for squinting, blurry distance vision, headaches, eye rubbing or difficulty focusing.
• Ask open-ended questions about what your child actually sees.
• Follow recommended childhood vision screening and eye-care guidance.
• If your child has myopia, ask whether it is progressing.
• Ask your eye care professional about available myopia-management options.
• Encourage regular outdoor time.
• Break up prolonged periods of close work and screen use.
• Try the 20-20-20 rule.
• Use an eye care professional locator to find a provider near you.

Myopia may be common, but that doesn't mean parents have to simply watch it progress. Knowing the signs, building healthy visual habits and starting the conversation with an eye care professional can help families act earlier.

For more information, visit essilor.com.

References

1. Vitale S, Sperduto RD, Ferris FL 3rd. Increased prevalence of myopia in the United States between 1971-1972 and 1999-2004. Arch Ophthalmol. 2009;127(12):1632-1639. doi:10.1001/archophthalmol.2009.303.

2. Holden BA, Fricke TR, Wilson DA, et al. Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology. 2016;123(5):1036-1042. doi:10.1016/j.ophtha.2016.01.006.

3. Gifford KL, Richdale K, Kang P, et al. IMI – Clinical management guidelines report. Invest Ophthalmol Vis Sci. 2019;60(3).

4. Morgan IG, Wu PC, Ostrin LA, et al. IMI risk factors for myopia. Invest Ophthalmol Vis Sci. 2021;62(5):3. doi:10.1167/iovs.62.5.3.

5. Bullimore MA, Brennan NA. Myopia control: why each diopter matters. Optom Vis Sci. 2019;96(6):463-465. doi:10.1097/OPX.0000000000001367.

6. U.S. FDA. FDA authorizes marketing of first eyeglass lenses to slow progression of pediatric myopia. Sep 2025. https://www.fda.gov/news-events/press-announcements/fda-authorizes-marketing-first-eyeglass-lenses-slow-progression-pediatric-myopia

7. American Academy of Ophthalmology. Computers, digital devices and eye strain. American Academy of Ophthalmology. Accessed August 26, 2026.

8. Haarman AEG, Enthoven CA, Tideman JWL, Tedja MS, Verhoeven VJM, Klaver CCW. The complications of myopia: a review and meta-analysis. Invest Ophthalmol Vis Sci. 2020;61(4):49. doi:10.1167/iovs.61.4.49.

Here are four key areas to keep in mind when choosing backup power for your kitchen's most essential appliance.

1. Focus on fit and placement

Especially if you live in a small home or apartment, every inch counts. You'll need a backup power solution that fits easily in a narrow gap whether that's beside, behind or on top of your refrigerator. Unfortunately, many dedicated fridge backup units on the market today run close to 2.9 inches thick, which can make it challenging to fit in a narrow space.

One great solution is the ultra-slim 2.6-inch FridgeGuard from Jackery, a global leader of essential home backup, innovative solar generators and portable power stations. This unit comes with a gravity sensing display that automatically adjusts between portrait and landscape, depending on which way you want to mount it. FridgeGuard also weighs nearly half of what many competitors' models weigh, making it easier to fit anywhere in your kitchen.

2. Choose design that makes a difference

Because your fridge backup may be highly visible in your kitchen, you'll want a design that looks good and easily blends into the room.

FridgeGuard was developed with the award-winning industrial design studio Huge Design in California, and is the winner of five international design awards: iF Design Award, MUSE Design Awards, Green Good Design Award, A' Design Award and Competition and SHOP Design Award. The unit boasts a paint-free metal injection molded front cover with a quick release, customizable design.

3. Seek technology created with purpose

The last thing you want in a backup system is to pay for a huge amount of capacity your fridge will never use, that can't act quickly enough to ensure your fridge won't lose power, or that puts undue strain on your refrigerator's motor.

Instead of the significantly higher output most comparable units carry, FridgeGuard's 800W rated output and 1600W surge capacity are sized specifically to what a refrigerator actually draws, roughly 100W to 200W continuous with startup surges up to 800W.

FridgeGuard's Delay Start mode also gives your refrigerator compressor a moment before restart, easing strain on the motor and extending backup runtime. You can choose Delay AC mode to relieve the refrigerator compressor or a sub-10ms UPS to seamlessly restart your refrigerator so that the compressor won't stop at all.

The result? A system built around one job: making sure your refrigerator retains power.

4. Select an accessible, well-priced unit

The last thing you want is to spend money on an electrician on top of buying expensive backup power that's more than you need. Unlike other units that require installation, FridgeGuard simply plugs in and is ready to go, no installation or electrician required, making it a practical choice for renters and first-time buyers.

And unlike the roughly $900 price point of other major dedicated fridge backup systems currently on the market, FridgeGuard starts at $549.99 at Costco, providing a more accessible, affordable unit to protect your fridge through an outage.

Backup you can count on

With FridgeGuard you'll also get a five-year warranty, plus a LiFePO4 battery rated for 6,000 charge cycles at 70% capacity retention, which translates to 16 years of reliable daily use. Choosing a smart solution can give you peace of mind, even during an extended power outage.

Learn more at Jackery.com.

"I went through all stages of grief," Erik said. "At first, I was in denial. I thought if I exercised more and ate healthier, it would just go away."

Although he made healthy lifestyle changes, managing his glucose still felt like guesswork. Traditional fingersticks offered only snapshots of information, leaving him without a clear understanding of how his daily decisions impacted his glucose levels.

"I didn't want to guess — I wanted information I could actually use," Erik said.

Erik grew frustrated that diet and exercise alone weren't giving him the answers he needed. As someone who embraces technology in all aspects of his life and work, he began researching additional tools and learned about continuous glucose monitors (CGMs).

As he explored his options, Erik realized he would need a prescription and a conversation with his doctor to determine whether a CGM was right for him. Armed with what he learned, he was able to have an informed and specific conversation with his doctor, about his goals and diabetes management. Together, they decided Abbott's FreeStyle Libre 3 Plus sensor was a good fit, enabling him to follow his glucose levels in real time and gain insight into how his food intake, activity and daily habits affected his glucose levels.

By taking the initiative to ask about CGM technology, Erik was able to play an active role in his care and have an informed, collaborative conversation with his doctor. His experience reflects a common barrier: research shows that one in five people living with diabetes feel they need their doctor to suggest or recommend new tools, rather than feeling empowered to ask about those options themselves¹.

What is a CGM?

A continuous glucose monitor (CGM), like Abbott's FreeStyle Libre 3 Plus sensor, is a small, discreet sensor worn on the back of your upper arm that continuously measures your glucose levels every minute, day and night². It sends glucose readings directly to a compatible smartphone app³ or reader⁴, providing real-time information and trends.

Rather than relying on a single glucose reading obtained from prior methods like fingersticks, a CGM provides a complete picture of how meals, activity and medication affect glucose levels over time.

Why switch to a CGM?

For Erik, seeing those trends, not just individual numbers, gave him the insights he needed to make changes in his daily routine that made an impact.

"Having access to this data is empowering. It allows me to manage my diabetes proactively and avoid challenges that could set my whole day off course," said Erik. "My CGM is a huge reason why I feel more confident and in control of my health."

Research continues to demonstrate the benefits of CGM technology. In a recent study, people with Type 2 diabetes using a CGM lowered their HbA1c, a key marker of blood sugar levels, by 0.6% more than those using traditional fingersticks and spent about 2.5 additional hours each day in a healthy glucose range⁶.

Like Erik, many people with diabetes find that having continuous glucose information can provide a clearer understanding of how food, activity and other daily habits affect their glucose levels, helping them make more informed decisions⁵.

How to talk to your doctor about CGM

If you or someone you love is living with Type 2 diabetes, consider talking to a doctor about options and whether a CGM is technology to consider. Not sure how to start the conversation? Check out these helpful tips:

1. Do your homework: Learn about available CGM options, including Abbott's Libre systems, so you can ask informed questions and better understand how the technology works.
2. Learn how CGM works: Ask your doctor about the value CGMs provide and how they can help you better understand your glucose patterns.
3. Share your goals: Talk with your doctor about what you'd like to achieve, whether that's understanding how food affects your glucose, reducing routine fingersticks or feeling more confident in your daily habits.
4. Discuss your challenges: Be open about what's difficult when managing your glucose today and ask about insurance coverage and available support programs.
5. Find the right fit together: Managing diabetes is a team effort. Talk with your doctor about whether a CGM aligns with your individual needs, treatment goals and lifestyle.

For Erik, taking that first step to ask his doctor about a CGM changed the way he lives with diabetes.

"Talking to my doctor about a CGM was one of the best decisions I made after my diagnosis," Erik said. "I'm healthier now than I've ever been. You can't manage what you can't measure — data is power. The more you understand your diabetes, the more you can take charge of your life."

To learn more about CGMs and Abbott's Libre systems, click here.

The views expressed should not be used for medical diagnosis or treatment or as a substitute for professional medical advice. Individual symptoms, situations and circumstances may vary.

1. Data on file, Abbott Diabetes Care.
2. 60-minute warm-up required when applying the sensor.
3. The FreeStyle Libre systems apps are only compatible with certain mobile devices and operating systems. Please check our website for more information about device compatibility before using the apps. Use of the FreeStyle Libre systems apps may require registration with LibreView.
4. For U.S. residents - The FreeStyle Libre systems apps and the FreeStyle Libre systems readers have similar but not identical features. Fingersticks are required for treatment decisions when you see Check Blood Glucose symbol and when your glucose alarms and readings from the system do not match symptoms or expectations.
5. Fokkert, Marion, et al. "Improved Well-Being and Decreased Disease Burden After 1-Year Use of Flash Glucose Monitoring (FLARE-NL4)." BMJ Open Diabetes Research & Care 7, no. 1 (2019): e000809. https://doi.org/10.1136/bmjdrc-2019-000809.
6. Wilmot EG. Lancet Diabetes Endocrinol (2026). https://doi.org/10.1016/S2213-8587(26)00076-8

For U.S. residents - Important Safety Information Product for prescription only, for Important Safety Information please visit FreeStyleLibre.us.

ADC-2697391 v1.0

When Tia Newman was diagnosed with metastatic triple-negative breast cancer (TNBC), a cancer that has spread to other parts of the body,¹ it was already deeply personal. The 55-year-old Washington, D.C., area native had lost her mother and sister to the same aggressive disease.

Losing family members to TNBC fundamentally changed how Tia experienced her own diagnosis and underscored the burden this disease places on Black women.² As she began navigating metastatic TNBC, she quickly learned that her care would involve much more than medical treatment.

Black women are diagnosed with TNBC at nearly three times the rate of white women³ and are 38% more likely to die from breast cancer than white women, highlighting ongoing differences in breast cancer care and survival.² As efforts continue to address these disparities, the goal is to ensure people have access to trusted guidance and practical support throughout their care journey, alongside advances in treatment.

For Tia, support came through Care for HER, a national initiative from Unite for HER and TOUCH, The Black Breast Cancer Alliance. Care for HER connects Black women with free resources including integrative therapies, health education and around-the-clock, culturally tailored nurse navigation.

Support for the Whole Person

Through Care for HER, Tia received support tailored to what she needed outside of the doctor's office, supplementing the caregiver support she received from her husband and children. The program's "Wellness Passport" fully funds and delivers services such as professional counseling, nutrition consultations, exercise classes and fresh grocery deliveries.

As Tia dealt with severe weight loss and fatigue during treatment, she worked with a dietitian and used meal kits tailored to her pescatarian diet, helping her regain strength.

"When you have cancer, support is bigger than just medical appointments," Tia shared. "Having an outside navigator and real people to talk to who guide you through the tears makes a massive difference."

That whole-person approach is at the heart of Care for HER.

"Our vision is that every Black individual diagnosed with breast cancer will feel supported and have access to comprehensive integrative oncology care that manages arduous side effects, supports treatment adherence and gives those we serve their lives back," said Sue Weldon, CEO and Founder of Unite for HER.

"Care for HER's nurse navigation program aims to directly address a considerable need among Black breast cancer patients, providing services and support that they might not be able to access otherwise," said Ricki Fairley, CEO of TOUCH, The Black Breast Cancer Alliance. "Together, we're ensuring these women receive the comprehensive care and guidance they deserve."

Care for HER's focus on helping people navigate needs beyond treatment aligns with Gilead Sciences' Community Cancer Collective (CCC), which supports the program alongside other sponsors.

"Gilead's CCC brings together community organizations, healthcare providers, advocates and local leaders to help reduce barriers to cancer care, with patient navigation as a core pillar of its work," said Darren Tayama, MD, Vice President, U.S. Medical Affairs, Oncology at Gilead. "Through Care for HER, we are proud to support a program that is delivering whole-person support, an often-overlooked but essential aspect of addressing persistent disparities for Black women facing breast cancer."

Removing Barriers to Care

During Breast Cancer Awareness Month this October, Tia is encouraging other women to pay attention to their bodies, ask questions and seek support from the beginning of their cancer experience.

That includes asking care teams about navigation programs and other resources that can help with the emotional, nutritional and practical challenges that may come with treatment.

"Don't let cancer absorb your mind," Tia advised. "Pushing through with the right support in your corner makes all the difference."

To learn more about free patient navigation, integrative therapies and holistic support through Care for HER, visit uniteforher.org/careforher. For additional information and resources from Gilead Sciences, Inc., for people living with metastatic breast cancer and those who support them, visit expose-mbc.com.

As a Registered Dietitian Nutritionist navigating perimenopause, I'm always thinking about how to best support my body and mind as I age. I'm also selective about supplements. I don't take many, so if something earns a place in my routine, there has to be a good reason.

Creatine monohydrate is one of the few that has made the cut. Every morning, I mix a scoop into my orange juice. It's a simple habit, but one I've come to rely on because of the strong research behind it and the way I feel when I take it consistently.

Many people still think creatine is only for bodybuilders or people trying to bulk up, but that's a limited view. Beyond supporting muscle performance, strength and recovery, creatine also plays an important role in cellular energy and may benefit cognitive function during menopause. That's one reason why I think it deserves more attention, especially during life stages like perimenopause, menopause and andropause. Healthy Aging Month is a great opportunity to learn more about this natural energy source.

How creatine powers your cells

To understand how creatine works, let's take a quick step back to high school biology. You might remember the Krebs cycle and ATP (adenosine triphosphate). ATP is the primary energy currency your cells use for everything from moving a muscle to solving a puzzle.

However, your body's ATP stores are limited. They deplete quickly when energy demands rise. This is where creatine steps in. It helps your cells regenerate ATP more efficiently, acting as a rapid energy reserve.

This mechanism makes creatine valuable well beyond the gym. One question I hear often is: Does creatine help with perimenopause fatigue? Based on the available evidence, there's reason to think it can, particularly by supporting cellular energy during periods of hormonal flux, poor sleep or mental strain. It won't replace good sleep or a balanced diet, but for women navigating menopause-related muscle loss and energy dips, it's one of the more well-researched tools available. By helping to ensure your cells have a steady energy supply, creatine supports resilience when your body is working harder to maintain it.

Does creatine help during perimenopause and menopause?

Hormonal changes during perimenopause and menopause bring noticeable shifts. Energy levels can dip, workouts often feel harder to recover from and mental clarity might not come as easily. These frustrating changes highlight exactly why creatine is so relevant right now.

Throughout a woman's lifespan, hormonal fluctuations influence how the body produces, transports and uses creatine.¹ In other words, the times when you need steady energy and resilience the most are often the same times when your body's natural creatine dynamics are shifting.

Additionally, women may naturally produce less creatine and consume less of it through food compared to men.² This makes supplementation particularly relevant, especially as hormonal changes during menopause can impact areas like bone density, cognitive sharpness and muscle strength, which are key aspects of health that often feel more vulnerable during this transition.

Emerging research suggests creatine may help support muscle strength, cognitive function, energy metabolism and exercise recovery during menopause.³ While it is not a treatment for menopause symptoms, it may help address some challenges associated with hormonal changes.

What are the benefits of creatine for brain and muscle health?

What I find most compelling about creatine is how its benefits overlap. We don't experience muscle health, mental clarity, recovery and mood as separate systems. They're interconnected!

When creatine supports ATP production, it provides fuel for muscle contractions. This can improve your training quality and help preserve lean muscle mass. At the same time, it fuels your brain cells. The brain is an incredibly energy-hungry organ. Some data link creatine supplementation to improved memory, attention and processing speed in adults, and it may enhance cognitive performance by increasing cellular energy reserves and reducing oxidative stress in the brain.⁴

Creatine for men and andropause

Creatine isn't just a conversation for women. Men also experience age-related hormonal shifts, often referred to as andropause. As testosterone declines, men may notice losses in muscle mass, reduced strength, lower energy and changes in focus or mental sharpness.

Because creatine supports ATP regeneration, it can help address these challenges. For aging men, this means support for strength, training capacity and lean mass, while also helping maintain mental energy and cognitive performance. The underlying biology is the same: when cells can produce and recycle energy more efficiently, both physical and cognitive performance benefit.

How much creatine should you take?

Most research on creatine monohydrate uses a maintenance dose of 3–5 grams per day. Experts generally recommend taking creatine consistently each day to maintain elevated muscle creatine stores.⁵

Keeping it simple

When I talk with clients about supplements, I encourage simplicity. But creatine is one of the few supplements I consistently recommend during this life stage because the research is broad, the mechanism makes sense, and it's easy to use.⁵

When choosing a product, I recommend a third-party-tested creatine monohydrate without unnecessary additives. Doctor's Best Creatine Powder is a great example; it's unflavored, vegan and easy to mix into orange juice, water or a smoothie, making it a seamless addition to your routine.

The bottom line

Creatine isn't just a supplement; it's a small but powerful way to support your body and mind through life's transitions. Whether you're navigating the hormonal shifts of perimenopause or menopause, or simply looking to maintain strength, energy and clarity as you age, creatine offers a science-backed solution that's easy to incorporate into your routine. For me, it's not about chasing perfection; it's about feeling strong, capable and clear-headed in the moments that matter most. And that's why creatine has earned its permanent spot in my morning orange juice, and I encourage clients in this life-stage to explore it too.

Frequently Asked Questions

• What does creatine do? Creatine is a naturally occurring compound that helps your body produce and recycle ATP (adenosine triphosphate), the primary source of energy used by your cells. While it's best known for supporting muscle strength and exercise performance, creatine also plays an important role in brain function, recovery, and cellular energy production throughout the body.
• Can creatine help with brain fog? Research suggests that creatine may support cognitive function by helping brain cells maintain adequate energy levels. Some studies have linked creatine supplementation to improvements in memory, attention and information-processing speed, particularly during periods of metabolic stress, sleep deprivation or aging. While creatine is not a treatment for menopause-related brain fog, it may help support overall brain health and mental clarity as part of a healthy lifestyle.⁴
• Does creatine help with fatigue? Because creatine helps regenerate cellular energy, it may help support physical and mental energy demands. Some women find that creatine helps them feel more resilient during periods of hormonal change, intense exercise or poor sleep.
• How much creatine should I take? Most research on creatine monohydrate supports a daily maintenance dose of 3–5 grams per day. While some people choose to start with a short loading phase, it's not necessary. Taking 3–5 grams daily consistently will gradually increase and maintain creatine stores in your muscles and other tissues.⁵
• When should I take creatine? The most important factor is consistency. Creatine can be taken any time of day, as long as you take it regularly. Long-term daily use is generally more important than the specific timing of supplementation.

These statements have not been evaluated by the Food and Drug Administration. This product and information is not intended to diagnose, treat, cure, or prevent any disease. This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a physician. Consult your physician or healthcare provider before beginning any supplement or lifestyle program.

References

¹ Smith-Ryan, A. E., Cabre, H. E., Eckerson, J. M., & Candow, D. G. (2021). Creatine Supplementation in Women's Health: A Lifespan Perspective. Nutrients, 13(3), 877. https://doi.org/10.3390/nu13030877

² Smith-Ryan, A. E., DelBiondo, G. M., Brown, A. F., Kleiner, S. M., Tran, N. T., & Ellery, S. J. (2025). Creatine in women's health: bridging the gap from menstruation through pregnancy to menopause. Journal of the International Society of Sports Nutrition, 22(1). https://doi.org/10.1080/15502783.2025.2502094

I'd been told I could be numb. I didn't understand what that reality actually meant.

Before my mastectomy, sensation wasn't something I thought about. The warmth of someone's hand or the pressure of a seatbelt across my chest didn't require conscious attention for me to know it was there. My body simply told me what was happening.

Until it didn't.

When Your Body Doesn't Feel Like Your Body

During a mastectomy, nerves that provide feeling to the breast and chest are cut as part of the procedure. It is necessary to remove cancerous tissue. Without surgical intervention to reconstruct those nerves, the majority of women are left numb after a mastectomy. I was only told the day of my surgery that I might experience numbness. But it was an afterthought, just another side effect on a long list of risks and complications I was already trying to understand and reconcile. It sounded temporary. Manageable. Certainly not something that would fundamentally change the way I experience my own body. After surgery, my chest "healed" according to medical standards, but to me, it still felt unfamiliar and disconnected from the rest of my body. What I saw and what I felt no longer matched.

That disconnect is difficult to explain unless you've lived it.

It can make your body feel foreign. It can change intimacy, how you experience touch, how you move through completely ordinary moments. Numbness isn't visible. To the people around me, I looked healed. But healing and feeling whole aren't necessarily the same thing. Without anyone realizing it, I had to navigate an entirely new relationship with my body.

I hug people tighter because I can't fully feel it against my chest. I've burned myself without realizing it. Clothing and seatbelts can feel strange. I pay attention to pressure and temperature in ways I never had to before. Sometimes, there is the simple, unsettling realization that I'm touching my own body and can't feel it.

For me, one of the hardest parts was the shift from never thinking about sensation to thinking about it every day. Many times a day.

It's Not Just Me

For a long time, these experiences felt deeply isolating. They weren't the things people talked about when they discussed breast cancer survival. Then I read the results of a national survey of more than 300 women who had undergone mastectomy, and I saw myself in their shared experiences.

Nearly nine in 10 women reported experiencing chest numbness or loss of feeling. One in four reported burns, cuts or other injuries related to their numbness. More than half reported depression or sadness, and 57% said they no longer felt like the woman they once were.

But one stat struck me especially hard: 54% said they stayed silent because they felt they should "just be grateful."

I understand that silence. I survived the thing I feared most, yet I still grieve something I never expected to lose. Sometimes I wonder if I should feel that loss so deeply when I am fortunate to still be here.

Gratitude Doesn't Cancel Grief

There is enormous pressure around survivorship to be grateful. And I am grateful. I am alive. But it's possible to experience gratitude and grief together. Many of us do.

Grieving what cancer and treatment took from me doesn't diminish the gift of survival. Talking about numbness doesn't mean I don't appreciate the care that saved my life. Missing what my body used to feel like doesn't make me any less thankful to still be here.

Surviving changed me. And that's the part of survivorship I wish we talked about more openly. Gratitude and grief aren't opposites.

When numbness is invisible, it is easy for everyone around you — and eventually even for you — to assume that once the scars heal, you're okay. But the end of treatment isn't necessarily the end of what cancer changes for survivors.

There Is Life After Cancer

Maybe you're facing a mastectomy now. Maybe you had one years ago and you're trying to find the words for something you've felt (or lost) all along. Or maybe you love someone who has survived breast cancer and never realized this could be part of her experience.

What I wish I had understood is that numbness isn't a small side effect. It's not a footnote. It changes the way you move through the world and how you experience your own body.

The cancer may be gone, but I still carry the changes it brought into my life.

I don't share this to diminish survival. I share it because I survived breast cancer, but healing didn't make me feel whole again. And no woman should have to discover and live with that alone.

Cara Bisegna is a breast cancer survivor and a patient advocate focused on improving education and informed decision-making in women's health. Cara is a paid spokesperson for Axogen, Inc.

Katy is contracted with Bristol Myers Squibb as an unpaid spokesperson, reflecting on her personal experiences with Opdivo Qvantig. Results may vary for others.

Vijay K. Gunuganti, M.D., medical oncologist and hematologist at Texas Oncology, was compensated by Bristol Myers Squibb for his contribution to this article.

For many, retirement represents a long-awaited opportunity to focus on the things that matter most — family, travel, hobbies and the freedom to enjoy life's next chapter. For Katy, that was exactly the plan. After years of balancing work, family responsibilities and busy schedules, she was looking forward to slowing down. She envisioned spending more time playing pickleball, swimming, traveling with her husband and being with her family.

Then everything changed.

A routine medical evaluation led to an unexpected and staggering diagnosis: Stage IV melanoma.

Melanoma is a type of skin cancer. When diagnosed at Stage IV, the cancer cells have spread beyond their original location in the skin to distant lymph nodes or other vital organs. An advanced diagnosis is challenging for any patient to navigate and for Katy, the news was devastating. Suddenly, the retirement that she had spent years planning was overshadowed by uncertainty, fear and difficult decisions about treatment.

"I had so many thoughts running through my mind, especially the fear that if my daughter has a child, they won't have a grandmother," Katy recalls, reflecting on those first difficult days following her diagnosis.

But after the initial shock wore off, Katy made a decision. Rather than letting cancer define her future, she would become an active participant in her care. She wanted to understand her options, partner closely with her healthcare team and make choices that were right for her lifestyle — not simply manage a diagnosis.

Partnering for a path forward

Katy's first step was to find a trusted oncologist with whom she could collaborate to build a treatment plan to target her melanoma. Over the course of her care plan, she was treated with Opdivo Qvantig^® (nivolumab and hyaluronidase-nvhy), an immunotherapy given by subcutaneous (under the skin) injection. As an immunotherapy treatment, Opdivo Qvantig works with the immune system to help fight cancer and is the first approved subcutaneous PD-1 inhibitor. Specifically, Opdivo Qvantig binds to PD-1 receptors on immune cells, which helps the body's natural defenses detect and target the cancer.

Opdivo Qvantig, Opdivo^® (nivolumab) and Yervoy^® (ipilimumab) can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work, which can be serious or life threatening and can lead to death.

INDICATION & SUMMARY OF WARNINGS AND PRECAUTIONS

Opdivo Qvantig is a prescription medicine used alone to treat adults and children 12 years of age and older who weigh 66 pounds (30 kg) or more with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma), after completing combination treatment with intravenous nivolumab and ipilimumab.

Opdivo Qvantig is not indicated for co-administration with Yervoy.

Opdivo is a prescription medicine used in combination with Yervoy to treat adults and children 12 years of age or older with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma).

Opdivo Qvantig, IV Opdivo and IV Yervoy can cause problems that can sometimes become serious or life-threatening and can lead to death. Serious side effects may include lung problems; intestinal problems; liver problems; hormone gland problems; kidney problems; skin problems; eye problems; problems in other organs and tissues; and complications of stem cell transplant, including graft-versus-host disease (GVHD), that uses donor stem cells (allogeneic). Call or see your healthcare provider right away for any new or worsening signs or symptoms. Opdivo is associated with severe infusion reactions.

Please see the Important Safety Information at the end of this article.

Opdivo Qvantig works with the immune system the same way as IV Opdivo but is delivered differently, providing eligible patients and healthcare providers with an additional administration option. Opdivo Qvantig may let patients receive immunotherapy treatment administration quickly* — in as fast as three minutes (injection time of Opdivo Qvantig is three to five minutes) — with an injection under the skin instead of a 30-minute IV infusion of Opdivo into a vein. It is given by a healthcare professional in the stomach area (abdomen) or thigh area. Opdivo Qvantig doesn't need to be administered at an infusion center and may be given at a doctor's office or a site closer to home. Since the medication is injected under the skin and no access to a vein is required, a port may not be necessary.

"For patients navigating an advanced cancer diagnosis, having an administration option that fits their lifestyle is incredibly meaningful," says Dr. Vijay Gunuganti. "Having a subcutaneous option like Opdivo Qvantig allows us to deliver an immunotherapy treatment that works with the immune system in the same way as IV Opdivo, but through a different administration method. While the IV formulation of Opdivo remains a viable option of care, Opdivo Qvantig allows eligible patients to choose another treatment administration method that can be delivered faster*, with a three- to five-minute injection. This addition is a welcome step forward in giving eligible patients more options and may help them integrate cancer care into their daily routines."

*A three- to five-minute injection time of Opdivo Qvantig compared to 30-minute infusion time of IV Opdivo. This does not account for all aspects of treatment and does not include observation time. Actual clinic time may vary.

Embracing a future full of gratitude

Katy's melanoma diagnosis gave her a new perspective, especially on how she viewed accepting help from others.

She welcomed steady support and daily care of her friends, husband and daughter. This helped her deepen her gratitude for the everyday, teaching her to cherish small moments, the people around her and the time they have together. And Katy has much to appreciate — she and her husband recently celebrated their 50th wedding anniversary and are proud new grandparents. She is relishing her role as a grandmother.

By staying active in her own care, Katy felt empowered through having options in how she received treatment.

"Having a choice in how my treatment was administered gave me options to choose from during a time when so much felt out of my hands," Katy shares. "Opting for the subcutaneous injection allowed me to receive treatment in my local doctor's office, making the process easier on my family. I focused on what truly mattered to me: fighting to overcome cancer."

For others who are currently at the beginning of their own cancer journey, Katy offers simple, heartfelt advice: "The antidote to that fear was being grateful," she says. "I am just so full of gratitude for the life that I have."

How to Learn More

To read more inspiring patient and caregiver stories visit: Patient and Caregiver Stories | OPDIVO^® & OPDIVO Qvantig^®

Indications and Important Safety Information

INDICATIONS

OPDIVO QVANTIG^® (nivolumab and hyaluronidase-nvhy) is a prescription medicine used alone to treat adults and children 12 years of age and older who weigh 66 pounds (30 kg) or more with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma), after completing combination treatment with intravenous nivolumab and ipilimumab.

OPDIVO^® (nivolumab) is a prescription medicine used in combination with YERVOY^® (ipilimumab) to treat adults and children 12 years of age or older with a type of skin cancer called melanoma that has spread or cannot be removed by surgery (advanced melanoma).

It is not known if OPDIVO QVANTIG is safe and effective in children younger than 12 years of age with melanoma.

It is not known if OPDIVO QVANTIG is safe and effective in children for the treatment of any other cancers.

It is not known if OPDIVO is safe and effective in children younger than 12 years of age with melanoma.

It is not known if OPDIVO is safe and effective in children for the treatment of any other cancers.

IMPORTANT SAFETY INFORMATION FOR OPDIVO QVANTIG, OPDIVO, and YERVOY

What is the most important information I should know about OPDIVO QVANTIG, OPDIVO, and YERVOY?

OPDIVO QVANTIG, OPDIVO, and YERVOY are medicines that may treat certain cancers by working with your immune system. OPDIVO QVANTIG, OPDIVO, and YERVOY can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. These problems may happen anytime during treatment or even after your treatment has ended. You may have more than one of these problems at the same time. Some of these problems may happen more often when OPDIVO QVANTIG or OPDIVO are used in combination with another therapy.

Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:

Lung problems: cough; shortness of breath; chest pain

Intestinal problems: diarrhea (loose stools) or more frequent bowel movements than usual; stools that are black, tarry, sticky, or have blood or mucus; severe stomach-area (abdominal) pain or tenderness

Liver problems: yellowing of your skin or the whites of your eyes; severe nausea or vomiting; pain on the right side of your stomach area (abdomen); dark urine (tea colored); bleeding or bruising more easily than normal

Hormone gland problems: headaches that will not go away or unusual headaches; eye sensitivity to light; eye problems; rapid heartbeat; increased sweating; extreme tiredness; weight gain or weight loss; feeling more hungry or thirsty than usual; urinating more often than usual; hair loss; feeling cold; constipation; your voice gets deeper; dizziness or fainting; changes in mood or behavior, such as decreased sex drive, irritability, or forgetfulness

Kidney problems: decrease in your amount of urine; blood in your urine; swelling of your ankles; loss of appetite

Skin problems: rash; itching; skin blistering or peeling; swollen lymph nodes, painful sores or ulcers in mouth or nose, throat, or genital area; fever or flu-like symptoms

Eye problems: blurry vision, double vision, or other vision problems; eye pain or redness

Problems can also happen in other organs and tissues. These are not all of the signs and symptoms of immune system problems that can happen with OPDIVO QVANTIG, OPDIVO, and YERVOY. Call or see your healthcare provider right away for any new or worsening signs or symptoms, which may include:

• Chest pain, irregular heartbeat, shortness of breath or swelling of ankles
• Confusion, sleepiness, memory problems, changes in mood or behavior, stiff neck, balance problems, tingling or numbness of the arms or legs
• Double vision, blurry vision, sensitivity to light, eye pain, changes in eyesight
• Persistent or severe muscle pain or weakness, muscle cramps
• Low red blood cells, bruising

Rejection of a transplanted organ or tissue. Your healthcare provider should tell you what signs and symptoms you should report and monitor you depending on the type of organ or tissue transplant that you have had.

Getting medical treatment right away may help keep these problems from becoming more serious. Your healthcare provider will check you for these problems during treatment with OPDIVO QVANTIG, OPDIVO, and YERVOY. Your healthcare provider may treat you with corticosteroid or hormone replacement medicines. Your healthcare provider may also need to delay or completely stop treatment with OPDIVO QVANTIG, OPDIVO, or YERVOY if you have severe side effects.

What are the possible side effects of OPDIVO QVANTIG, OPDIVO, and YERVOY?

OPDIVO QVANTIG, OPDIVO, and YERVOY can cause serious side effects, including:

• See "What is the most important information I should know about OPDIVO QVANTIG, OPDIVO, and YERVOY?"
• Complications, including graft-versus-host-disease (GVHD), in people who have received a bone marrow (stem cell) transplant that uses donor stem cells (allogeneic). These complications can be severe and can lead to death. These complications may happen if you underwent transplantation either before or after being treated with OPDIVO QVANTIG, OPDIVO, or YERVOY. Your healthcare provider will monitor you for signs of complications if you have an allogeneic stem cell transplant.

OPDIVO and YERVOY can cause serious side effects, including:

• Severe infusion reactions. Tell your healthcare team right away if you get these symptoms during an infusion of OPDIVO or YERVOY: chills or shaking; itching or rash; flushing; shortness of breath or wheezing; dizziness; feel like passing out; fever; back or neck pain.

The most common side effects of OPDIVO QVANTIG when used alone in people with renal cell carcinoma include: pain in muscles, bones, and joints; feeling tired; itchy skin; rash; low thyroid hormone levels; diarrhea; cough; stomach-area (abdominal) pain.

The most common side effects observed with nivolumab given into the vein (intravenous nivolumab), which may be experienced with OPDIVO QVANTIG, are shown below.

The most common side effects of OPDIVO, when used alone, include: feeling tired; rash; pain in muscles, bones, and joints; itching; diarrhea; nausea; weakness; cough; shortness of breath; constipation; decreased appetite; back pain; upper respiratory tract infection; fever; headache; stomach-area (abdominal) pain; vomiting; and urinary tract infection.

The most common side effects of OPDIVO, when used in combination with YERVOY, include: feeling tired; diarrhea; rash; itching; nausea; pain in muscles, bones, and joints; fever; cough; decreased appetite; vomiting; stomach-area (abdominal) pain; shortness of breath; upper respiratory tract infection; headache; low thyroid hormone levels (hypothyroidism); constipation; decreased weight; and dizziness.

These are not all the possible side effects. For more information, ask your healthcare provider or pharmacist. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088.

Before receiving OPDIVO QVANTIG, OPDIVO, or YERVOY, tell your healthcare provider about all of your medical conditions, including if you:

• have immune system problems such as Crohn's disease, ulcerative colitis, or lupus.
• have received an organ transplant, including corneal transplant.
• have received or plan to receive a stem cell transplant that uses donor stem cells (allogeneic).
• have received radiation treatment to your chest area in the past and have received other medicines that are like OPDIVO, YERVOY, or OPDIVO QVANTIG.
• have a condition that affects your nervous system, such as myasthenia gravis or Guillain-Barré syndrome.
• are pregnant or plan to become pregnant. OPDIVO QVANTIG, OPDIVO, and YERVOY can harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if OPDIVO QVANTIG, OPDIVO, or YERVOY passes into your breast milk. Do not breastfeed during treatment and for 5 months after your last dose of OPDIVO QVANTIG, OPDIVO, or YERVOY.

Females who are able to become pregnant:

• Your healthcare provider should do a pregnancy test before you start receiving OPDIVO QVANTIG, OPDIVO, or YERVOY.
• You should use an effective method of birth control during treatment and for 5 months after your last dose of OPDIVO QVANTIG, OPDIVO, or YERVOY. Talk to your healthcare provider about birth control methods that you can use during this time.
• Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with OPDIVO QVANTIG, OPDIVO, or YERVOY.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Please see U.S. Full Prescribing Information and Medication Guide for OPDIVO QVANTIG, U.S. Full Prescribing Information and Medication Guide for OPDIVO, and U.S. Full Prescribing Information and Medication Guide for YERVOY.

Clinical Trials and Patient Populations

Checkmate 67T–previously treated advanced or metastatic clear cell renal cell carcinoma with OPDIVO QVANTIG; Checkmate 067–previously untreated unresectable or metastatic melanoma, as a single agent or in combination with YERVOY.

© 2026 Bristol-Myers Squibb Company.
OPDIVO^®, YERVOY^®, and OPDIVO Qvantig^® are trademarks of Bristol-Myers Squibb Company. All other trademarks are property of their respective owners. [1992-US-2600464 09/26]

It happens so often we hardly notice: Head to the kitchen, grab a glass from the cabinet, fill it with water from the faucet.

Tap water is one of many conveniences of modern everyday life that we rarely, if ever, think about. And that's by design — thanks to years of technological innovation before many of us were even born.

Behind the walls and under the streets, networks of PVC and CPVC water pipes quietly exist to safely and efficiently transport clean water from treatment plants to our taps.

Here's how it's done.

The science behind PVC

PVC pipes may look simple, but they're backed by a lot of science.

PVC is a widely used plastic that serves as the foundation for many products people encounter every day. It begins with two primary building blocks: chlorine derived from common salt and ethylene from natural gas. The material can then be formulated for different applications, including durable water pipes, flooring and vinyl records. There are several different types of PVC pipes, with each made to meet the performance needs of each specific use, like small-diameter CPVC pipes supplying drinking water in your home or the large blue or teal-colored pipes carrying water from the town to neighborhoods.

So what does it all mean?

All of that manufacturing, developed and engineered and innovated over decades, is what makes your PVC pipes something you don't have to think about much.

1. Safe for drinking water: All pipes used for drinking water, including PVC pipes, must meet NSF/ANSI 61, a rigorous international standard established using exhaustive testing methods to ensure the safety of clean drinking water. Manufacturer certification of PVC pipe to NSF/ANSI 61 means that it is safe for use in drinking water piping applications — and has been for decades.
2. Long-lasting, durable and reliable: Unfortunately, communities across the U.S. lose an estimated 6 billion gallons of treated water a day to pipe breaks, leaks and aging infrastructure, according to a 2021 report by the American Society of Civil Engineers. PVC pipe is providing an ideal solution: Properly installed, PVC pipes are engineered for long-term service and are widely recognized for their durability and resistance to corrosion. Studies of water infrastructure have found that PVC pipes can provide reliable service for many decades, contributing to their widespread use in drinking water and wastewater systems. In fact, a series of reports, the most recent in 2023, on water main breaks in the U.S. and Canada by Utah State University found that PVC pipe has the lowest overall failure rate compared to three other commonly used pipe materials.
3. A sustainable pipe choice: Communities that choose PVC for its durability also reap the benefits of a smaller carbon footprint for their infrastructure. When evaluated on a life cycle and carbon footprint perspective, PVC pipe has lower environmental impacts — lower embodied energy, lower use-phase energy and longer life attributes — compared to pipe used in similar applications made from materials like iron, cement and clay. When considering the impacts throughout the product life cycle, PVC pipes use much less energy to manufacture and transport, and they can operate for more than a century and need fewer replacements over their lifetime. (A Life Cycle Assessment of PVC Water and Sewer Pipe is available here.)

In addition, it takes up to 54% more energy to pump water through an 8-inch ductile iron pipe than it does through an 8-inch PVC pipe during the life of the system, because PVC's surface remains smooth throughout.

Beneath our streets and behind your walls, PVC pipes are silently humming along, faithfully bringing safe drinking water to your home's tap. Thanks to science and modern manufacturing, it's another everyday convenience that makes our lives a bit easier.

Learn more about PVC pipe and other vinyl products you use every day at www.vinylinfo.org. Download the Plastic Pipe and Fittings Association's PVC Piping Features & Benefits fact sheet here.

Ned Monroe is CEO of the Vinyl Institute.

The human body was made to move, and movement is part of nearly every moment of daily life. You walk from place to place, bend to pick something up, lift groceries, climb stairs, work at your desk, exercise, care for your family and make time for the hobbies you love. How you move today can heavily influence how active, independent and capable you are years from now.

When pain, stiffness or limited mobility get in the way, those everyday movements can feel harder or out of reach — affecting not only how you move, but also how you're able to participate in life. Over time, these limitations can negatively impact strength, flexibility, balance, posture, confidence and independence — all of which play an important role in long-term health and longevity.

Movement supports healthspan by helping maintain daily function, including stamina, strength, mobility, balance and recovery. So, how can you support healthy movement and maintain a good quality of life? One answer may be chiropractic care.

Why chiropractic care may be the secret to longevity

Chiropractic care can be a proactive and holistic way to support your body over time. That's because it aims to benefit the musculoskeletal system, the body's framework for posture, stability and movement, which consists of bones, muscles, ligaments, tendons and joints.

By supporting the musculoskeletal system through chiropractic care, patients may be able to restore and maintain better mobility, reduce recurring stiffness and stay more comfortable through daily activities that help them stay active and independent as they age.

Chiropractic care may also help relieve pain. In fact, one of the most common reasons people seek this type of treatment is for pain from old or existing injuries, as well as discomfort that can develop from the demands of everyday life, including prolonged sitting, driving, lifting and repetitive activities. When pain gets in the way, it can affect more than how you feel physically, changing how much you move, what you feel comfortable or confident doing and how fully you participate in daily life.

Move long and live fully

Living longer is only part of the goal. Staying active and moving well can help you maintain independence and quality of life as you age, and chiropractic care may be one way to support that. When movement patterns stay efficient, activity feels easier and recovery tends to improve. Supporting healthy movement may make a lasting impact, helping you stay active and maintain your independence as you age.

That said, to get the most benefit from chiropractic care, consistency is key. Just like going to the gym, eating a balanced diet and going on daily walks, routine chiropractic care becomes valuable when aligned with goals and lifestyle demands. Routine means establishing a consistent schedule for care, whether that means weekly, biweekly or another frequency decided on by you and your chiropractor. Over time, this consistency may help support healthy movement and mobility rather than waiting until pain or discomfort gets in the way.

The advantages of chiropractic care may include helping with comfort, range of motion, flexibility, muscle coordination, physical performance, circulation supported by easier movement, sleep quality and mental clarity. When chiropractic care is incorporated into daily life with a regular cadence, it may help the body feel less restricted and more settled.

To learn more about how chiropractic can help you invest in your long-term mobility and find a convenient, affordable clinic near you, visit TheJoint.com.

According to Children's Cancer Cause, approximately 15,000 children and adolescents are diagnosed with cancer each year in the U.S. There are more than 13 major types of pediatric cancers and more than 200 subtypes. One rare but incredibly challenging type of childhood cancer is high-risk neuroblastoma.

"Neuroblastoma is a cancer that develops from immature nerve cells and most commonly affects infants and young children," said Michele Ritter, a pediatric oncology nurse practitioner who worked closely with patients for over 30 years and now serves as a Clinical Nurse Educator at US WorldMeds. "While some forms can be treated successfully, children with high-risk neuroblastoma face a particularly difficult journey."

To help shine a light on high-risk neuroblastoma, highlight the importance of maintenance treatment and celebrate the role of caregivers, Ritter has answered some of the most common questions about high-risk neuroblastoma.

Why is high-risk neuroblastoma considered one of the most challenging childhood cancers?

The disease is aggressive and carries a significant risk of relapse, even after intensive treatment. Advances in treatment have improved outcomes, but preventing relapse remains one of the biggest challenges for families and healthcare providers.

Many people assume treatment ends when a child is declared cancer-free. Why is the period after remission still so important?

Achieving remission is a major milestone worth celebrating. However, it doesn't always mean the journey is over. Even when scans show no evidence of disease, cancer recurrence is still a concern. That's why physicians continue to monitor patients closely and may recommend additional strategies designed to help maintain remission and reduce the risk of relapse.

What is maintenance therapy?

After a patient has completed up-front therapy and achieved remission, they may be given maintenance therapy to help sustain the response already achieved and reduce the risk of the disease returning.

What do families need to know about the risk of relapse in high-risk neuroblastoma?

Relapse remains one of the biggest concerns in high-risk neuroblastoma. Even if children complete aggressive up-front therapy, about one-third of patients will experience relapse. That's why physicians remain focused on helping children achieve remission and implementing strategies that may help sustain it over time.

Childhood Cancer Awareness Month shines a spotlight on patients, but what about caregivers?

Caregivers are truly unsung heroes and play a vital role throughout every stage of the cancer journey. Parents and family members often spend months or even years navigating appointments, treatments, hospital stays and emotional challenges while advocating for their children every step of the way. Childhood Cancer Awareness Month is an opportunity to recognize and celebrate the resilience, dedication and essential role caregivers play in supporting children through treatment and recovery.

What message would you like families affected by high-risk neuroblastoma to hear this Childhood Cancer Awareness Month?

Families should know there's a real reason for hope, as advances in research and treatment continue to improve. They should also know they're not alone. There are multiple advocacy groups that can provide support and resources, and the medical community remains deeply committed to improving treatments, reducing the risk of relapse, and helping more children thrive long after cancer treatment ends.

• Occasional diarrhea is a common complaint in dogs and cats, and pet parents may not always know what to do about it.
• Diarrhea can have many causes, including stress or sudden change in diet.
• Purina Pro Plan Veterinary Supplements has created a non-prescription kit to help pet parents manage their pets' occasional diarrhea and long-term gut health.
• Call your vet if symptoms continue, worsen, or your pet experiences vomiting or changes in appetite or energy.

When a pet has diarrhea, pet parents may not know what to do, or when it's time to call their veterinarian. Diarrhea is one of the most common reasons pets feel under the weather, and it's not always obvious what will actually help.

In honor of the 2026 National Cat & Dog Gut Health Awareness Day on September 21, Purina Veterinary Nutritionist Martha Cline, DVM, DACVIM, explains how pet parents can ease their pet's tummy troubles, and keep their gut healthy so it's less likely to happen again.

How you can help your pet feel better

Diarrhea is a common complaint in dogs and cats, with a wide range of potential causes. Two common culprits are stress and diet. A change in routine, construction noise, a new pet or baby in the house or a sudden food switch can all play a role.

One or more of these strategies can help ease your pet's tummy troubles:

1. Keep their environment calm

Has life at home been chaotic? Help your pet relax and reset. For cats, that could mean a place to escape the hustle and bustle, like a cozy hideaway or special box. Dogs tend to do best when sticking closely to their routine. Providing extra one-on-one attention and a chew toy can also help dogs burn off nervous energy.

2. Introduce new foods more gradually

"If you've recently introduced a new food, it might not be sitting well with your cat or dog, especially if they have a sensitive stomach," said Dr. Cline. "A slower introduction, or mixing it with their usual food, can help their stomach adjust."

If your pet's diet has not changed, a temporary switch to a highly digestible or fiber-enhanced diet may help. Consult your vet before making any dietary changes.

3. Consider a supplement created just for pets

To give your dog or cat extra support, skip the human medicine cabinet and stick to supplements designed specifically for pets.

"The best supplements for pets are created in collaboration with veterinary nutritionists who have expertise in health and nutrition," said Dr. Cline.

FortiFlora Diarrhea Response Kit for pets (dogs; cats) with occasional diarrhea from Pro Plan Veterinary Supplements is one option. Developed by Purina scientists, it pairs FortiFlora Response stick packs for short-term use to help firm loose stools with FortiFlora sachets, the No. 1 vet-recommended probiotic brand to support digestive health*, with no prescription required. FortiFlora Response stick packs contain kaolin and pectin to soothe the GI tract during times of loose stool, and come in an easy-to-mix, liver-flavored powder you can pour right into your pet's bowl.

"Diarrhea can be difficult for pets and pet parents, but having a plan takes a lot of the stress out of it," said Dr. Cline. "Keeping the FortiFlora Diarrhea Response Kit on hand means you'll be ready whenever it strikes."

A diagnosis of non-muscle invasive bladder cancer (NMIBC) can quickly lead to new questions: What does this mean? What are my options? How will treatment fit into my life? With information coming from medical teams, online resources, loved ones and educational materials, it can be difficult to know where to start.

Dr. Anne Schuckman, Associate Professor of Clinical Urology and Director of Urologic Oncology at LA General Hospital, encourages people diagnosed with NMIBC and their loved ones to come prepared, ask questions and focus on what matters most to them.

"As the NMIBC treatment landscape evolves, people diagnosed with bladder cancer and their loved ones are making very personal decisions about care," said Dr. Schuckman. "Asking questions can help them understand not only what a treatment does, but how it may align with their priorities and long-term goals."

Making sense of bladder cancer information

Misconceptions about NMIBC can make treatment decisions harder. Some people may assume one approach is right for everyone or that bladder removal is the only remaining option if an initial treatment has not worked.

Today, some people diagnosed with NMIBC may have more options to discuss with their healthcare provider, including what treatments are available, how treatments work, how often they are given, what follow-up is needed, possible side effects and how treatment may fit into daily life.¹

For example, one option may be ADSTILADRIN^® (nadofaragene firadenovec-vncg), a prescription medicine for the treatment of adults with NMIBC whose cancer has not spread or responded to Bacillus Calmette-Guérin (BCG) treatment.² It is delivered directly into the bladder in an outpatient setting every three months and, for some people, may be part of a treatment plan that does not involve bladder removal.²

Like other medicines administered into the bladder for the treatment of certain bladder cancers, ADSTILADRIN may cause side effects.² The most common side effects include urinary discharge, fatigue, bladder spasm, urgency to urinate, and blood in your urine. People should talk with their healthcare provider to understand its potential risks and benefits.²

Building a support network

Having a good support network can reshape a patient's treatment experience. Along with doctors, nurses and loved ones, insurance and reimbursement assistance teams and advocacy organizations can help people navigate care. That support may be needed long after initial treatment.

In a recent survey of people living with bladder cancer, 79% said fear of recurrence defines the survivor experience, and 57% said they had never received a survivorship care plan despite 86% believing one was important.³ A survivorship care plan is a personalized document developed with your care team that explains what follow-up care and testing you may need, how to manage side effects, ways to stay healthy and what to watch for over time.

"People may not realize which resources are available to them," said Dr. Schuckman. "Their care team can help connect them with support, and loved ones can help them prepare for more productive conversations."

Questions that can guide the discussion

There is no single way to evaluate NMIBC treatment options.¹ These questions can help start the conversation:

• What is the stage of my cancer?
• What factors should I consider when choosing among my treatment options?
• How might each treatment fit into my daily life and care routine?
• What type of follow-up care or monitoring will be needed?
• Should I have a survivorship care plan, and what should it include?
• Are there treatment options that may help me avoid or delay bladder removal?
• Who can help me prepare for and make treatment decisions?

"You do not need to walk into an appointment being an expert in bladder cancer," said Dr. Schuckman. "What is most important is being ready to ask questions, share your priorities and work with your physician and their team to identify an approach that fits your needs."

For more information about ADSTILADRIN, please see Important Safety Information below and for Full Prescribing Information, visit https://www.adstiladrin.com/.

What is ADSTILADRIN?

ADSTILADRIN is a prescription medicine for the treatment of adults with a type of cancer of the lining of the bladder called non-muscle invasive bladder cancer (NMIBC), that has not spread to other parts of the body, and that did not respond to treatment with Bacillus Calmette-Guérin (BCG).

IMPORTANT SAFETY INFORMATION

Who should not receive ADSTILADRIN?

Do not receive ADSTILADRIN if you have a sensitivity to interferon alfa or any of its components.

What is the most important information I should know about ADSTILADRIN?

• Delaying removal of the bladder in patients with bladder cancer that is not responding to Bacillus Calmette-Guérin (BCG) therapy Carcinoma in situ (CIS) could lead to development of muscle-invasive or metastatic bladder cancer. The risk increases the longer bladder removal is delayed in the presence of persisting CIS.
• Individuals who are immunosuppressed or immune-deficient should not prepare, administer, receive or come into contact with ADSTILADRIN.

What are the possible side effects of ADSTILADRIN?

The most common side effects of ADSTILADRIN include: Urinary discharge, fatigue, bladder spasm, urgency to urinate, and blood in your urine. These are not all the possible side effects of ADSTILADRIN. For more information, ask your healthcare provider.

What should I tell my healthcare provider?

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information.

(BPT) - Sponsored by Ferring Pharmaceuticals

A diagnosis of non-muscle invasive bladder cancer (NMIBC) can bring a flood of questions: What does this mean? What are my options? What should I ask next?

Dr. Anne Schuckman, Associate Professor of Clinical Urology and Director of Urologic Oncology at LA General Hospital, encourages people diagnosed with NMIBC and their loved ones to come prepared, ask questions and talk openly with their care team about what matters most to them.

"As more options for NMIBC treatment become available, people diagnosed with bladder cancer and their loved ones are making complex and personal decisions about care," said Dr. Schuckman. "Coming prepared can help them ask not only what treatments are available and how they work, but how they may fit into their routine, priorities and long-term goals."

Making sense of bladder cancer information

Misconceptions about treatment options can make decision-making harder. Some people may think that if an initial treatment has not worked, bladder removal is the only remaining option, or that one treatment path applies to everyone.

Today, due to major advances in the field, many people diagnosed with NMIBC have more options to discuss with their healthcare provider than in the past.¹ Those conversations should include how treatments work, how often they are given, what follow-up is required, potential side effects and how treatment may fit into daily life.

For example, one option may be ADSTILADRIN^® (nadofaragene firadenovec-vncg). ADSTILADRIN is a prescription medicine for the treatment of adults with NMIBC whose cancer has not spread or responded to Bacillus Calmette-Guérin (BCG) treatment.² It is delivered directly into the bladder in an outpatient setting every three months and, for some people, may be part of a treatment plan that does not involve bladder removal.²

Like other treatments, ADSTILADRIN may cause side effects.² The most common side effects include urinary discharge, fatigue, bladder spasm, urgency to urinate, and blood in your urine. People should talk with their healthcare provider to understand its potential risks and benefits.²

Building a support system

People diagnosed with NMIBC do not have to navigate care alone. Support may come from doctors, nurses, loved ones, insurance and reimbursement assistance teams, and advocacy organizations. That support can matter well beyond initial treatment.

In a recent survey, 79% of people living with bladder cancer said fear of recurrence defines the survivor experience, while more than half said they had never received a survivorship care plan despite most believing one was important.³ A survivorship care plan is a personalized document developed with your care team that explains what follow-up care and testing you may need, how to manage side effects, ways to stay healthy and what to watch for over time.

"People may not realize the importance of building a support team," said Dr. Schuckman. "Their team can help connect them with resources, and trusted physicians and loved ones can help them process information and prepare for shared decision-making conversations."

Questions that may help guide the conversation

There is no single way to evaluate NMIBC treatment options.¹ These questions can help start the conversation:

• What is the stage of my disease?
• What factors should I consider when choosing among my treatment options?
• How does each option fit into my daily life and care routine?
• What follow-up or monitoring is required?
• Should I have a survivorship care plan, and what should it include?
• Are there treatment options that may help me avoid or delay bladder removal?
• Who can help me prepare for and make treatment decisions?

Asking questions, seeking trusted resources and speaking openly with your physician and their team can help people diagnosed with NMIBC take a more active role in care decisions.

"You do not need to have all the answers before walking into an appointment," said Dr. Schuckman. "The goal is to feel prepared to ask questions, share what matters to you and identify an approach that fits your needs."

For more information about ADSTILADRIN, including Important Safety Information and Full Prescribing Information, visit https://www.adstiladrin.com/.

What is ADSTILADRIN?

ADSTILADRIN is a prescription medicine for the treatment of adults with a type of cancer of the lining of the bladder called non-muscle invasive bladder cancer (NMIBC), that has not spread to other parts of the body, and that did not respond to treatment with Bacillus Calmette-Guérin (BCG).

IMPORTANT SAFETY INFORMATION

Who should not receive ADSTILADRIN?

Do not receive ADSTILADRIN if you have a sensitivity to interferon alfa or any of its components.

What is the most important information I should know about ADSTILADRIN?

• Delaying removal of the bladder in patients with bladder cancer that is not responding to Bacillus Calmette-Guérin (BCG) therapy Carcinoma in situ (CIS) could lead to development of muscle-invasive or metastatic bladder cancer. The risk increases the longer bladder removal is delayed in the presence of persisting CIS.
• Individuals who are immunosuppressed or immune-deficient should not prepare, administer, receive or come into contact with ADSTILADRIN.

What are the possible side effects of ADSTILADRIN?

The most common side effects of ADSTILADRIN include: Urinary discharge, fatigue, bladder spasm, urgency to urinate, and blood in your urine. These are not all the possible side effects of ADSTILADRIN. For more information, ask your healthcare provider.

What should I tell my healthcare provider?

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see full Prescribing Information.

The good news? Many falls can be prevented. From staying active to making your home safer, a few simple steps can reduce your risk.

Stay active. Regular physical activity builds strength, balance, flexibility and mobility, which can reduce your risk of falling. Walking, gardening, dancing, swimming and strength training are just a few ways to keep moving. The Centers for Disease Control and Prevention recommends that adults get at least 150 minutes of moderate-intensity aerobic activity each week for optimal health benefits, but every step counts!

Talk with your healthcare provider. Some conditions increase your risk of falling. Ask about your personal risk factors and steps you can take to reduce them during your annual Medicare Wellness checkup.

Review your medications. Some prescriptions and over-the-counter medicines can cause dizziness, drowsiness or other side effects. Talk to a provider or pharmacist about your falls risk and read the label on your medicine to learn about precautions and potential side effects.

Stay hydrated. Drink fluids regularly throughout the day, even if you don't feel thirsty. Not drinking enough can cause dizziness, weakness and confusion, increasing your risk of falling. Women should aim for about nine cups per day and men about 13 cups, according to the Academy of Nutrition and Dietetics.

Take care of your vision. Seeing clearly helps you avoid obstacles and navigate your surroundings safely. Nightlights and motion detector lights can help light the way indoors and out. Get your vision checked regularly and keep your prescriptions up to date.

Make your home safer. Look for things that could cause you to trip or lose your balance. Keep walkways clear, improve lighting, secure or remove loose rugs, and install grab bars where you need extra support. A rubber tub mat, ideally with suction cups that create a firm seal against the floor, can help keep slippery feet on the ground.

Find a local program. Falls prevention classes and programs can help improve strength, balance and mobility while teaching you practical tips to reduce your risk of falling.

You don't have to do everything at once. Start with one or two steps that make sense for you and build from there.

Visit the Eldercare Locator, a public service of the Administration for Community Living, to help you find falls prevention programs and other services in your area or call 800-677-1116.

• Parents and caregivers can help prepare a child for surgery by following fasting and medication instructions and sharing complete information about the child's health.
• CRNAs, also known as nurse anesthesiologists or nurse anesthetists, provide anesthesia and pain management before, during and after procedures, including continuous monitoring during anesthesia.
• Visit AnesthesiaAnswers.org, a resource from the American Association of Nurse Anesthesiology (AANA), for practical information, questions to ask and recovery tips.

Facing a child's surgery can bring many questions. To help families find clear, practical information, the American Association of Nurse Anesthesiology created AnesthesiaAnswers.org, an online resource about anesthesia, procedures and recovery.

AANA represents Certified Registered Nurse Anesthetists (CRNAs), also known as nurse anesthesiologists or nurse anesthetists, who provide anesthesia and pain management before, during and after procedures.

To help families prepare, AANA offers the following guidance about what to expect before, during and after anesthesia.

What to know before surgery

You play an essential role in your child's safety because you know them better than anyone else.

"Parents are an important part of the anesthesia safety team," said Suzanne Wright, PhD, CRNA, FAANA, chair of AANA's Patient Safety Advisory Panel. "Follow your child's preoperative instructions carefully, and never hesitate to ask questions. Knowing when your child last ate, drank, or took medication, for example, can make a meaningful difference in keeping them safe during anesthesia."

Parents will receive specific instructions for their child about when to stop eating and drinking. Following these instructions exactly helps reduce the chance that food or liquid in the stomach could enter the lungs under anesthesia, a serious complication called aspiration.

What should I know before my child gets anesthesia?

Before surgery, a CRNA or other anesthesia professional will review when your child last ate or drank, discuss your child's health and assess their airway. Tell the CRNA about any current or recent respiratory illness — including a cold, flu or COVID-19 — and symptoms such as coughing, congestion, fever or wheezing, even if your child seems to have recovered. Recent respiratory infections can leave a child's airway more sensitive for several weeks and may increase the risk of breathing problems during or after anesthesia. Sharing this information helps the anesthesia team assess your child's individual risk and determine whether any changes to the anesthesia plan or timing of an elective procedure should be considered.

The CRNA will:

• Confirm past experiences: You'll be asked how your child has done with anesthesia before and about family history of rare reactions.
• Review anesthesia plan: They will explain the plan, introduce the anesthesia professionals caring for your child and review consent forms.
• Ease anxiety: Children may receive medication to help them relax by mouth, through the nose or through an IV, depending on their age. Child life specialists may be available to help reduce anxiety.

The most important thing to do before surgery is to follow all your healthcare provider's instructions.

Demanding careers. Evolving family priorities. Staying connected with partners. These are just a few of the pressures men may face in midlife. If these challenges were not enough, midlife can often be accompanied by the unwanted arrival of erectile dysfunction (ED).¹

A private, isolating struggle

Today, ED is becoming more prominent in everyday conversation. Advertisements and other forms of direct-to-consumer marketing are more visible across broadcast media and social channels. However, for some men, ED remains a private condition that can carry emotional and psychological burden.²

"The stigma and uncertainty surrounding ED can make men feel isolated at the very moment they need reassurance most," said Dr. Ralph Zagha, a board-certified urologist in Tamarac, FL. "It's a burden that's not limited to older populations, as we are seeing a number of cases of ED in men aged 18-44."³

An unsure treatment journey

Many men with ED do not seek or receive care, with U.S. data showing that only a small portion discuss symptoms with a healthcare provider.⁴ Finding the right treatment is often not a simple, one-step process.

Awareness may begin with frustration or confusion, followed by online searches or conversations with partners. Some individuals eventually consult clinicians in person, while others may turn to telehealth for more convenience, greater privacy and improved access to care.⁵

As telehealth expands and cultural attitudes shift, men are increasingly turning to ED treatment options that are convenient and discreet. Evidence suggests that embarrassment and privacy concerns contribute to this shift, with telehealth platforms offering more private and accessible care that may encourage seeking treatment.^6,7

Modern treatment options, designed for real life

Recent treatment advances are expanding how ED can be managed, potentially offering flexibility to fit individual needs and lifestyles. These features including simple dosing and no restrictions on food or water timing.⁸

With a range of dosing options and formulations available, care can be tailored based on personal needs and response.⁹ These innovations may help address common barriers and support men in seeking care.

Talk to your doctor

ED is a medical condition and treatment often begins with a conversation. Men experiencing symptoms or considering new options are encouraged to speak with a healthcare provider to better understand what approaches may be right for them.

Dr. Zagha is a paid consultant to IBSA Pharma Inc.

1. Charles, S. (October 2025). Erectile dysfunction and age: What you need to know. Verywell Health. https://www.verywellhealth.com/erectile-dysfunction-and-age-5200761
2. Allen, M. S., Wood, A. M., & Sheffield, D. (2023). The psychology of erectile dysfunction. Current Directions in Psychological Science, 32(6), 487–493. https://doi.org/10.1177/09637214231192269
3. Mark, K. P., Arenella, K., Girard, A., Herbenick, D., Fu, J., & Coleman, E. (2024). Erectile dysfunction prevalence in the United States: Report from the 2021 National Survey of Sexual Wellbeing. *The Journal of Sexual Medicine, 21*(4), 296–303. https://doi.org/10.1093/jsxmed/qdae008
4. International Society for Sexual Medicine. (n.d.). Prevalence of erectile dysfunction in the United States. ISSM Sexual Health Headlines. https://www.issm.info/sexual-health-headlines/prevalence-of-erectile-dysfunction-in-the-united-states
5. Li, M. K., Patel, D. P., & Hsieh, T.-C. (2025). Direct-to-consumer erectile dysfunction medications: Is the convenience worth the cost? Current Urology Reports, 26(1), 69. https://doi.org/10.1007/s11934-025-01302-3
6. Brink, S. M., Iarajuli, T., & Shin, D. (2023). Characteristics of direct-to-consumer platforms offering erectile dysfunction treatment. Sexual Medicine, 11(4), qfad038. https://doi.org/10.1093/sexmed/qfad038
7. Sexual Medicine Society of North America. (May 2024). The intersection of telemedicine and men's health. https://www.smsna.org/patients/news/the-intersection-of-telemedicine-and-mens-health
8. Pham, Q. M., Yannas, D., Sansone, A., Romero-Otero, J., Vendeira, P., Frangione, V., & Jannini, E. A. (2025). Food effect on pharmacokinetic profiles of sildenafil 100 mg oral films in healthy male volunteers: Results from two randomized, single dose, crossover studies. Sexual Medicine, 13(5), qfaf096. https://doi.org/10.1093/sexmed/qfaf096
9. Shen, J., Park, D., Bash, J., & Andino, J. (2026). Advances in erectile dysfunction management: What does work. Trends in Urology & Men's Health. https://doi.org/10.1002/tre.70027

For the second year in a row, Salesforce is helping more families experience this joy. The global tech company best known for helping organizations build more personalized and efficient customer relationships is doubling down. As the official Make-A-Wish^® match partner for Childhood Cancer Awareness Month (CCAM), Salesforce will match every donation, up to $1 million, throughout the month of September.

But Salesforce's commitment doesn't end after September. The tech company has already committed to supporting Make-A-Wish with an additional $1M match campaign during CCAM next year. Additionally, Salesforce's partnership with the nonprofit will include employee engagement opportunities, storytelling campaigns and wish celebrations throughout the year.

Salesforce's generosity has already helped make 100 wishes possible, with the Salesforce team hosting celebration events for three wish kids this year, including one child's unique wish: visit a construction-themed adventure park.

A wish that digs into joy

For 5-year-old Sam, joy means digging in the sand with his toy truck and bringing his imagination to life with LEGOs. So, when Make-A-Wish approached his family to bring Sam's wish to life, he knew without a doubt what his wish would be: to visit a construction-themed adventure park.

Sam and his family were able to drive, ride and operate real diggers, dump trucks and giant machines in a safe, family-friendly environment. Afterward, Sam visited the LEGO store in New York City.

"Sam had the time of his life at Diggerland and became a big fan of NYC!" said Sam's mom. "We can't thank you enough for making Sam's wish come true! Seeing him so happy was an absolute joy, and our whole family is still talking about all the fun we had. Thank you again for the trip of a lifetime!"

Before his trip, Salesforce invited Sam and his family to its San Francisco office, where they spent the day on a scavenger hunt of the city's famous landmarks from the office windows. This is just one example of how technology, compassion and community can bring hope and joy to families when it matters most.

How you can help double the joy

This September, every donation can have twice the impact, helping fund more wishes, reach more families and create more joy and hope for children navigating critical illnesses. To learn more and donate during Childhood Cancer Awareness Month, visit wish.org.

Lung cancer (both small cell and non-small cell) is the second most common cancer in the U.S.¹ In 2026 alone, it's estimated that nearly 230,000 new cases of lung cancer will be diagnosed.¹ Nearly half of all lung cancers are diagnosed at a later stage, after the cancer has spread from the lungs to more distant areas of the body.²

What is non-small cell lung cancer (NSCLC)?

The main types of lung cancer are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC is the most common type of lung cancer, making up more than 8 out of 10 lung cancers in the U.S.³

What causes NSCLC?

Many cancers are caused by gene changes, also called mutations. Genes are pieces of DNA that tell your cells how to work, and when gene mutations occur, they can change how the cells work.

For example, some gene mutations change how cells grow or multiply, causing them to grow or multiply too much, leading to cancer.

Gene mutations in NSCLC

Multiple gene mutations are associated with NSCLC. Specific mutations can influence how someone's cancer grows or spreads and how well available treatments may work in their case.

One specific gene mutation commonly found in NSCLC is the G12C mutation of the KRAS gene.^4,5 The KRAS G12C mutation causes cells to grow in an uncontrolled way, which can form tumors.⁶ About 13% of people (13 in 100) with advanced NSCLC have this specific mutation.⁴ Most KRAS G12C mutations are found in current or former smokers.^5,6

Biomarker testing can help determine if you have certain gene mutations. Doctors often recommend that people with NSCLC get biomarker testing to see what mutations their cancer has.⁷

What are clinical trials?

A clinical trial, also called a clinical study, is a type of research designed to learn more about how the human body responds to investigational medicines, vaccines or other treatments. Clinical trials are the only way treatments can be approved for public use.

Learn about an investigational medicine targeting KRAS G12C

The goal of one particular trial is to learn if an investigational medicine may help stop or slow down the growth of NSCLC with KRAS G12C mutations. It will compare:

• The investigational medicine combined with an immunotherapy, to
• An immunotherapy and a placebo.⁸ A placebo looks like the trial drug but has no medicine in it. Using a placebo helps researchers understand if the investigational medicine works.

This trial is for adults age 18 and older who⁸:

• Have been newly diagnosed with locally advanced or metastatic NSCLC. Locally advanced or metastatic means the cancer has spread to other parts of the body or cannot be removed with surgery.
• Have the KRAS G12C mutation.
• Have the PD-L1 protein on their cancer cells. PD-L1 is found on some cancer cells and can help the cancer hide from the body's immune system. To learn if you have PD-L1, doctors test a tissue sample from a tumor.

More about this trial

There are more eligibility criteria for this trial. There may be risks related to participating in clinical trials. The trial doctor can discuss these with you.

Participation in clinical trials is voluntary, and participants are free to leave at any time, for any reason. Participants may help contribute to data that may advance research and potentially help future generations learn more about the investigational medicine and NSCLC.

Advancing research through representation

Representation in clinical trials helps researchers gain a more complete picture of how investigational medicines work across populations. This helps support the development of safe and effective medicines for those who are most affected by the disease or condition being studied.

"Diseases can impact people differently based on their age, gender, race, and ethnicity, as well as other factors," said Michelle Chawla, clinical trial representation program lead at Merck. "That's why it's important for clinical trials to include people from a wide variety of backgrounds. By participating in a clinical trial, you can help researchers understand how investigational treatments may work across different populations and contribute to data that may advance research."

See if you or a loved one may be eligible for a clinical trial

You can learn more about this clinical trial at Merck's clinical trial page.

References

1. American Cancer Society. Key statistics for lung cancer. Updated January 13, 2026. Accessed April 23, 2026. https://www.cancer.org/cancer/types/lung-cancer/about/key-statistics.html
2. Centers for Disease Control and Prevention. U.S. cancer statistics lung cancer stat bite. Updated June 2, 2025. Accessed May 5, 2026. https://www.cdc.gov/united-states-cancer-statistics/publications/lung-cancer-stat-bite.html
3. American Cancer Society. What is lung cancer? Updated January 29, 2024. Accessed May 6, 2026. https://www.cancer.org/cancer/types/lung-cancer/about/what-is.html
4. Lim TKH, Skoulidis F, Kerr KM, et al. KRAS G12C in advanced NSCLC: prevalence, co-mutations, and testing. Lung Cancer. 2023;184:107293. doi:10.1016/j.lungcan.2023.107293
5. Cascetta P, Marinello A, Lazzari C, et al. KRAS in NSCLC: state of the art and future perspectives. Cancers (Basel). 2022;14(21):5430. doi:10.3390/cancers14215430
6. American Lung Association. KRAS and lung cancer. Updated December 2, 2025. Accessed May 6, 2026. https://www.lung.org/lung-health-diseases/lung-disease-lookup/lung-cancer/symptoms-diagnosis/biomarker-testing/kras
7. American Lung Association. Lung cancer biomarker testing. Updated January 20, 2026. Accessed June 4, 2026. https://www.lung.org/lung-health-diseases/lung-disease-lookup/lung-cancer/symptoms-diagnosis/biomarker-testing
8. Merck & Co, Inc. MK-1084-004: learn about a clinical trial for non-small cell lung cancer (NSCLC) with KRAS G12C mutations. Merck Clinical Trials. Published 2025. Accessed May 6, 2026. https://www.merckclinicaltrials.com/trial/nct06345729/

Ahead of National Cat & Dog Gut Health Awareness Day on September 21, Purina Veterinary Nutritionist Martha Cline, DVM, DACVIM, shares some tips on what pet parents should know about easing their pet's tummy troubles as soon as possible and keeping their gut healthy so it's less likely to happen again.

What's causing your pet's diarrhea?

Diarrhea is a common complaint in both dogs and cats, with a wide range of potential causes, but there are two common culprits: diet and stress. A sudden food switch, a change in routine, new construction noise, or even a new pet or baby in the house can all play a role.

3 ways to help your pet feel better

1. Slowly introduce new foods

"If you've recently introduced a new food, it might not be sitting well with your cat or dog," said Dr. Cline. "A slower introduction, or mixing it with their usual food, can help their stomach adjust." If your pet's diet has not changed, a temporary switch to a highly digestible or fiber-enhanced diet may help. Confirm with your vet before making any changes.

2. Provide a quiet environment

If things have been chaotic at home lately, give your pet a way to reset. For cats, that could be a place to escape the hustle and bustle, like a cozy hideaway or a special box of their own. Dogs tend to do best when sticking closely to their routine. Extra one-on-one attention and a chew toy can also help burn off nervous energy.

3. Consider a supplement

For extra support, skip the human medicine cabinet and stick to supplements designed specifically for pets.

"The best supplements for pets are created in collaboration with veterinarians with expertise in health and nutrition," said Dr. Cline.

FortiFlora Diarrhea Response Kit for pets (dogs; cats) with occasional diarrhea from Pro Plan Veterinary Supplements is one option. Developed by Purina scientists, it pairs FortiFlora Response stick packs for short-term use to help firm loose stools with FortiFlora sachets — the No. 1 vet-recommended probiotic brand to support digestive health*, no prescription required. FortiFlora Response stick packs contain kaolin and pectin to soothe the GI tract during times of loose stool, and come in an easy-to-mix, liver-flavored powder you can pour right into your pet's bowl.

"Diarrhea can be difficult for pets and pet parents, but having a plan takes a lot of stress out of it," said Dr. Cline. "Keeping something like the FortiFlora Diarrhea Response Kit on hand means you're ready no matter when it strikes."

Additional signs to watch for

It helps to note how long the diarrhea lasts and any other symptoms that show up. These details can point to whether there's a bigger issue.

"If you notice vomiting, changes in appetite or energy, or diarrhea that isn't improving or worsens within 72 hours, it's time to call your veterinarian," added Dr. Cline.

The 3 a.m. bathroom trip. The conversation neither person wants to have. The hygiene routine that suddenly takes up the whole morning. These daily moments can take an emotional and physical toll on both caregivers and the people they care for.

"One of the biggest adjustments that I see families face is realizing that caregiving isn't just about managing a medical condition; it's about navigating dozens of everyday moments that can quickly become overwhelming," says Yolanda Rhodes, MSN, RN, CRRN, Senior Clinical Solutions Manager-Home Care, BD Urology and Critical Care. "The good news is that in my experience, with the right preparation and support, families can feel much more confident caring for their loved ones and may be better equipped to manage some of challenges that come with caregiving."

Here are four everyday caregiving challenges families may not anticipate, and practical ways to navigate them.

1. The Bathroom Challenge

Helping a loved one with bathroom needs is often one of the most physically demanding and emotionally delicate parts of caregiving. Whether due to urinary incontinence, limited mobility or recovery from surgery or illness, toileting assistance can quickly become a daunting part of the daily routine. Beyond the physical demands, it can also be uncomfortable and embarrassing for the person receiving care.

"Caregivers often worry about saying the wrong thing or making their loved one feel embarrassed," says Rhodes. "In my experience as a nurse, approaching these moments calmly and matter-of-factly can help preserve dignity and puts everyone more at ease."

What helps: Keeping essential supplies, like wipes, gloves and a change of clothes, within easy reach. Ensure the path to the bathroom is safe and accessible and consider adding grab bars near the toilet or a toilet seat riser to provide support for the person you're caring for.

2. The Nighttime Disruptions

From helping a loved one safely in and out of bed to responding to overnight bathroom needs or changing bedding after an accident, nighttime disruptions can leave caregivers exhausted and increase the risk of falls or injury when navigating the dark.

"Nighttime can be one of the most challenging parts of caregiving because everyone is tired and simple tasks become more difficult," Rhodes says. "Many caregivers find that finding ways to minimize overnight disruptions, whether through consistent bedtime routines or tools that help reduce unnecessary trips out of bed, may help make nighttime care smoother."

What helps: Keep frequently used items within easy reach and make sure pathways between the bed and bathroom are clear and well-lit. If nighttime urinary incontinence is causing frequent trips out of bed or overnight cleanup, products such as the BD PureWick^® Urine Collection System may help. This non-invasive, external urine management option is designed for overnight use and can support more uninterrupted sleep for both caregivers and loved ones. Supporting this benefit, a recent study published in the Journal of Clinical Medicine[1] found that women using the BD PureWick^® Urine Collection System reported better sleep and greater overall comfort, highlighting the system's ease of use and non-invasive design.

3. The Tough Talks

Few caregiving responsibilities are as emotionally difficult as discussing changing care needs with a loved one. Whether it's accepting help, giving up certain activities or acknowledging that daily tasks have become more difficult, these conversations can be emotional for everyone involved. Rather than trying to address everything in one major discussion, it can help to approach them as a series of smaller conversations over time.

What helps: Try framing each conversation around what your loved one maintains rather than what they're giving up. Importantly, caregivers don't necessarily have to navigate these conversations alone. Consider bringing a doctor or nurse in when needs begin to change can provide additional guidance and support during difficult conversations.

4. The Hygiene Hurdles

Daily activities that seem simple, like bathing, dressing and grooming, can often become more complicated than families expect. These routines require close physical assistance while balancing privacy, comfort and a loved one's desire to remain as independent as possible. Physical limitations, mobility challenges and fatigue can make these routine tasks that once felt automatic take considerably more time and patience.

What helps: Preparing ahead and building in extra time can help make these routines less overwhelming. Gather towels, toiletries and clothing before getting started so everything is within easy reach. Ask your loved one how you can make the process feel most like their own — whether it's their preferred bathroom temperature, choosing the outfit they had in mind or following the step-by-step skincare routine they've always used. Encourage your loved one to do the parts they can safely manage on their own while offering assistance where it's needed.

Don't Forget the Caregiver

Family caregivers devote enormous amounts of time and energy to supporting the people they love. Yet many put their own well-being last.

"Caring for someone else starts with caring for yourself," Rhodes says. "Accept help when it's offered, lean on your support system and remember that you don't have to do everything alone. Taking care of yourself can help maintain your well-being while continuing to support a loved one."

If you're unsure how to adapt to a loved one's changing needs, healthcare professionals can help you identify the next steps that best support you both. With the right routines, tools and support, the day-to-day may become more manageable, for both you and your loved one.

Yolanda Rhodes, MSN, RN, CRRN, is a nurse and BD associate. The opinions expressed are based on her professional experience and are not intended as medical advice. Individuals should consult their healthcare provider regarding their specific care needs.

Indications for Use: The PureWick^® Urine Collection System is to be used with PureWick^® External Catheters which are intended for non-invasive urine output management.

Contraindications for Use: Do not use the PureWick^® Urine Collection System with PureWick^® External Catheters on individuals with urinary retention.

Safety and Warnings: Always unplug PureWick^® Urine Collection System before cleaning or when not in use.

When she was just 14 years old, Sarah Johnson Lowery's pediatrician noticed something abnormal with her heart during a routine checkup. Despite no other initial symptoms, Lowery was referred to a cardiologist and diagnosed with obstructive hypertrophic cardiomyopathy (oHCM), a chronic condition that could be fatal.¹

HCM is the most common inherited heart condition, with more than 300,000 patients diagnosed in the U.S. alone.¹ Despite its prevalence, HCM remains widely misunderstood, resulting in an estimated 400,000 to 800,000 additional people who remain undiagnosed.^2,3,4 For people living with the condition, the journey from initial diagnosis to managing daily life is a testament to personal resilience.

Turning a sudden diagnosis into lifelong purpose

For Lowery, HCM arrived without warning, forcing her to change her active lifestyle and give up her spot on her high school's dance team.

"It was a scary time for my family and me. We had never heard of HCM before and didn't know what to expect," Lowery said. "I didn't have any symptoms at the time, so it was hard to come to terms with having a chronic heart condition at such a young age."

HCM is a disease in which the heart muscle becomes abnormally thick, limiting the heart's ability to pump. This can make it difficult to keep up with everyday physical activities and lead to symptoms like chest pain, dizziness and shortness of breath. HCM can be obstructive, when thickened muscle blocks blood flow, or non-obstructive, when blood flow is not blocked, but heart function is still affected. At least half of people diagnosed with HCM have the obstructive form, known as oHCM.⁵

After trying several treatments, Lowery eventually underwent a successful heart transplant at just 19 years old. Now 25, she says her experience with oHCM pushed her to be the person she is today, including shaping her role as a labor and delivery nurse.

Caption: Lowery after receiving a heart transplant at 19 years old. Source: Courtesy of Sarah Johnson Lowery

"Aside from my scar, HCM can be an invisible illness," she said. "I think it's made me more compassionate because you never know what someone is going through."

Lowery is looking forward to a future filled with travel, building a house and starting a family with her husband, Chance. And with recent research and treatment advancements, she hopes others can approach HCM with similar optimism.

Caption: Sarah Johnson Lowery and her husband, Chance, who has not been diagnosed with oHCM. Source: Courtesy of Sarah Johnson Lowery

"So much progress has come about since I was first diagnosed, from new technologies to medications. There is so much good to focus on," she said.

While Sarah's journey ultimately required a transplant, her story underscores the need for earlier, disease-specific interventions. Today, recent research advancements aim to change the landscape of oHCM management to make more treatment options available to patients who could benefit from them.

An era of targeted treatment

Historically, oHCM treatments focused primarily on managing symptoms or utilizing invasive procedures.⁵ However, decades of research have recently culminated in a treatment class designed to target the underlying cause of the disease.⁶

MYQORZO™ (aficamten) is the latest FDA-approved prescription medicine to treat adults with symptomatic oHCM to help improve functional capacity and symptoms.⁶

"For years, our approach to oHCM relied heavily on managing symptoms. Having a therapy that targets the underlying thickening of the heart muscle marks a fundamental shift in how we can care for these patients," said Michael Nassif, M.D., cardiologist at St. Luke's Mid America Heart Institute and co-investigator in MYQORZO's Phase 3 clinical trial.

Nassif shared that MYQORZO has a Boxed Warning for the risk of heart failure due to systolic dysfunction, and it is only available through a restricted distribution program called the MYQORZO Risk Evaluation and Mitigation Strategy Program.⁶

"For those on this therapy, our focus is on comprehensive, ongoing care, which includes routine echocardiograms every three or six months once the maintence dose is achieved to closely monitor heart function for ongoing safe use," Nassif added.

Do not take MYQORZO if you take a medicine called rifampin. MYQORZO can cause serious side effects, including heart failure, which is why your doctor will monitor how your heart is functioning. The most common side effect of MYQORZO is high blood pressure.

To learn more about how MYQORZO works, including full prescribing information, please visit www.MYQORZO.com and always discuss safety considerations and regular monitoring needs with your physician.

Sarah Johnson Lowery and Dr. Michael Nassif were compensated for their participation in this story. Sarah Johnson Lowery is not a patient on MYQORZO.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MYQORZO?

MYQORZO can cause serious side effects, including:

• Heart failure, a condition where the heart cannot pump with enough force, is a serious condition that can lead to death. You must have echocardiograms (echos) before and during treatment with MYQORZO and monitor for signs and symptoms of heart failure. People who develop a serious illness such as a serious infection or who develop a new or worsening irregular heartbeat have a greater risk of heart failure during treatment with MYQORZO
  
  Tell your healthcare provider or get medical help right away if you develop new or worsening shortness of breath, chest pain, fatigue, leg swelling, a racing sensation in your heart (palpitations), or rapid weight gain.
  
  
• The risk of heart failure is also increased when MYQORZO is taken with certain other medicines. Tell your healthcare provider about any prescribed and over-the-counter medicines you take, before and during your treatment with MYQORZO
  
  
• Because of the risk of heart failure, MYQORZO is only available through a restricted distribution program called the MYQORZO Risk Evaluation and Mitigation Strategy (REMS) Program
  

• Your healthcare provider must be enrolled in the MYQORZO REMS Program for you to be prescribed MYQORZO
  
  
• Before you start treatment with MYQORZO, you must enroll in the MYQORZO REMS Program. Talk to your healthcare provider about how to enroll in the program. You will be given information about the program when you enroll
  
  
• Before you take MYQORZO, your healthcare provider and pharmacist will make sure you understand how to take MYQORZO safely, which will include returning for echos when advised by your healthcare provider. MYQORZO can only be dispensed by a certified pharmacy that participates in the MYQORZO REMS Program
  
  
• If you have any questions about the MYQORZO REMS Program, ask your healthcare provider, go to www.MYQORZOREMS.com, or call 1-844-285-7367

Who should not take MYQORZO?

Do not take MYQORZO if you take a medicine called rifampin.

What are the possible side effects of MYQORZO?

MYQORZO can cause serious side effects, including heart failure.

What should I tell my healthcare provider before taking MYQORZO?

Before taking MYQORZO, tell your healthcare provider about all of your medical conditions, including if you:

• Are pregnant or plan to become pregnant. It is not known if MYQORZO can cause harm to your unborn baby. Tell your healthcare provider if you become pregnant during treatment or within 3 weeks after the last dose of MYQORZO. There is a pregnancy study for MYQORZO. Your healthcare provider should report your pregnancy exposure to Cytokinetics, Inc.
• Are breastfeeding or plan to breastfeed. It is not known if MYQORZO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with MYQORZO

Before and during MYQORZO treatment, tell your healthcare provider about all the prescription and over-the-counter medicines, vitamins, and herbal supplements you take. Taking MYQORZO with certain medicines may lead to increased levels of MYQORZO in your blood and increase the risk of heart failure. Do not stop or change the dose of a medicine or start a new medicine without telling your healthcare provider.

Especially tell your healthcare provider if you take fluconazole (if used for more than 3 days), voriconazole, or fluvoxamine.

What are the most common side effects of MYQORZO?

The most common side effect of MYQORZO is high blood pressure (hypertension).

These are not all the possible side effects of MYQORZO. Talk to your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to Cytokinetics at 1-833-633-2986.

INDICATION AND USAGE

MYQORZO is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (oHCM) to improve functional capacity and symptoms.

It is not known if MYQORZO is safe and effective in children.

Please see full Prescribing Information, including Boxed WARNING, and Medication Guide.

© 2026 CYTOKINETICS. All Rights Reserved.

US-MYQ-00424 08/2026

• Sandwich generation caregivers are challenged with care, costs and concerns for two generations simultaneously.
• The stress of caring for someone with Alzheimer's or Parkinson's is at a higher intensity and longer period than other situations, but also brings joy and connection with loved ones.
• Dementia caregivers need professional caregiver help to understand the neurodegeneration and progressive nature of Alzheimer's, Parkinson's and other diseases, and to help with their own burnout.
• Professional in-home caregiver services from Comfort Keepers provides older adults with expert care, helping adult daughters or sons with a trusted partner so they can have breaks, and spend more quality time and make joyful memories with their parent.

By Sherri Snelling, gerontologist and Comfort Keepers spokesperson

If you are a caregiver who belongs to the sandwich generation, you are performing a delicate balancing act: caring for children and older parents, maybe while also working. You stretch your time, energy and emotional resources thin and have little time for "me time" or self-care. The good news is, while caregiving can be disruptive, it is also one of the most powerful expressions of love. The key is finding ways to connect joyfully with aging parents, and being proactive in getting help so you can enjoy your time together.

According to the 2026 National Day of Joy survey conducted by Talker Research on behalf of Comfort Keepers, 93% of aging adults say being cared for by an adult son or daughter has brought them closer together, and 96% of caregivers in the sandwich generation say family comes first. The strength of these familial bonds is clear, but that does not mean you do not need support as you try to meet the needs of your children, your parents and yourself.

These pressures can become even more intense and complex when a parent is living with Alzheimer's disease, Parkinson's disease or another progressive, degenerative condition. Studies have found the intensity of dementia caregiving creates more stress, anxiety and depression, and these caregivers spend twice as long in their caregiving role. According to the Alzheimer's Association, dementia caregiving is an average of 9 years versus 4.5 years for other types of family caregiving. Caregiving becomes a marathon, not a sprint, creating the need for professional help to maintain your physical and mental energy.

How do I maintain my well-being while caring for my aging parent?

Caring for yourself is one of the biggest challenges for family caregivers. The additional time needed to care for someone with dementia or a neurodegenerative disease like Alzheimer's or Parkinson's while maintaining work-life balance and raising children makes the sandwich generation dementia caregiver sacrifice their own social, emotional and physical health. You may also be burdened with the stigma of diseases that affect the brain and avoid social interactions and conversations. Thus, you feel all alone.

This isolation means many adult children carry the entire caregiving burden alone, and feel they cannot or should not ask for help. Time is spent on physical and administrative caregiving tasks like tracking medical appointments, administering medications, managing insurance paperwork, getting groceries and prepping meals. What gets lost are the small moments of joy that really matter: enjoying a meal together, looking at old photos or sharing common interests like music, nature or crafts that create quality of life for the older parent and the adult daughter or son.

To help sandwich generation caregivers get back to what matters most, here are common myths around caregiving, and approaches that help families thrive.

Myth No. 1: Mom or Dad is safe, so everything is OK.

Reality: Quality of life matters, too. Caregiving is not just about physical tasks and safety such as doctor appointments, preventing harmful falls and personal care. Social health and avoiding loneliness are equally important. Companionship, favorite routines and activities, conversation and sharing moments of joy help an older adult and the family caregiver feel connected and engaged.

Myth No. 2: I should be able to handle this myself.

Reality: Caregiver burnout is real. Creating your care team is critical. Many adult children assume care responsibilities gradually, until you are spending 20-40 hours of week on care tasks. This can lead to burnout and can negatively impact your relationship with your parent. Professional caregivers, such as the in-home care specialists at Comfort Keepers, can become a part of your family's care team before a crisis happens. With this professional help, you can take breaks to recharge and practice needed self-care, so you can be more focused on the emotional needs instead of the medical needs of your loved one.

Myth No. 3: We will get help when we really need it.

Reality: Getting help before your parent's care reaches a crisis can make the caregiving journey easier for everyone. Progressive conditions such as Alzheimer's disease and Parkinson's can affect memory, communication, mobility, mood, personality, daily routines and eventually activities of daily living such as eating, hydrating, getting dressed or bathing. Planning ahead gives families time to have necessary conversations about long-term care, find the right professional caregiver, establish familiar routines and create a care plan that can evolve along with their parent's needs and a family's finances.

Myth No. 4: Every visit needs to be productive.

Reality: Sometimes the most important thing is simply being your parent's son or daughter. Professional caregiving can take some everyday responsibilities off your shoulders, so your time with your parent is not always consumed by errands, household tasks and caregiving duties. By being "present," you enhance the emotional health of your parent and yourself.

How can I keep my relationship with my aging parent intact?

Caring for a parent with dementia, Alzheimer's and Parkinson's is emotionally difficult for family caregivers. Alzheimer's adults may forget your name or who you are, and they may become combative and physically lash out, especially if experiencing sundowning. A son or daughter of someone with Parkinson's realizes they may have frightening hallucinations and nightmares. All of this occurs in addition to their declining physical and cognitive abilities.

The Comfort Keepers survey reveals that daily joy for aging adults is rooted in the connection found in everyday life moments: sitting outside, enjoying morning coffee or engaging in meaningful hobbies such as reading, gardening, crafts and music. These moments foster consistency, independence and a sense of purpose. And they give the family caregiver a moment of calm in the midst of chaos.

For someone living with Alzheimer's or Parkinson's, these activities may need to be adapted as the condition progresses. A familiar song from their past, a simplified gardening activity, a short walk or time spent looking through family photographs can offer connection, comfort and a sense of purpose. The goal is not necessarily to do things exactly as before, but to find meaningful ways to meet the person where they are today.

For adult children, joy is found in everyday connection with aging parents. The survey also found nearly 3 in 4 (72%) say simple conversations bring the most joy, followed by sharing meals (68%) and helping provide care for them (67%). A whopping 95% of adult children agree older adults play an important role in creating joy within their families.

Where do I start looking for a caregiver?

Comfort Keepers understands the challenges families face when caring for a loved one with Alzheimer's disease or Parkinson's, particularly as their needs change. Specially trained caregivers can help them continue living safely and meaningfully at home through personalized care, familiar routines, companionship and activities tailored to their interests and abilities. Comfort Keepers can also educate families about their changing needs and provide support that engages them physically, mentally and emotionally.

Comfort Keepers provides in-home services like:

• Personal care
• Companionship
• Medication reminders
• Family respite care
• Comfort360™: A Complete Circle of Care

You do not have to choose between being a good parent, partner, employee and caregiver as you juggle your roles. Professional caregiving can help you remain your parent's daughter or son first. Getting professional caregiver help from Comfort Keepers means better quality of life for your parent and for yourself.

Learn more about support for your loved one at ComfortKeepers.com.

If you know certain foods trigger heartburn but still eat them anyway, you're not alone, as many Americans are willing to make that tradeoff. According to a new PEPCID^® brand survey, almost half of respondents knowingly eat or drink things they expect will cause heartburn. While avoiding these foods could help reduce the likelihood of acid reflux and discomfort after eating, 80% of respondents believe certain foods are "worth the risk."*

The good news is that you do not have to pass on eating delicious dishes this fall. That is why having a heartburn game plan, including these five simple strategies, can help you manage symptoms and feel more prepared to enjoy the food you love at gatherings.

1. Elevate your upper body or stand up

When you lie down, increased pressure on the lower esophageal sphincter, the muscle that keeps the bottom of the esophagus closed, can worsen heartburn symptoms. Stand up after eating or elevate your upper body and head with a pillow to keep the stomach acid from flowing up into your esophagus.

2. Loosen tight clothing

Clothing that fits tightly around the waist can put pressure on your stomach, pushing its contents backward into the esophagus and causing discomfort. If you feel heartburn coming on, try loosening your belt or, when possible, opting for looser-fitting clothing to give your midsection more room to relax.

3. Chew gum to help reduce acid

Believe it or not, gum can help take the edge off a heartburn-triggering meal. Chewing gum boosts saliva production and makes you swallow more often, which can help clear acid from the mouth and esophagus. The best part? You'll get the added benefit of fresh breath.

4. Get moving

Did you know that regular exercise can help manage heartburn? Low-intensity aerobic exercises (walking, cycling and yoga) may offer protective benefits against acid reflux. These activities can also support a healthy weight, which is an important part of managing heartburn and acid reflux. However, you should try to avoid eating right after. The next time you eat a meal, invite a friend or family member to take a leisurely stroll around the block.

5. Have an acid reducer on hand

Many people who occasionally experience heartburn take a "wait and see" approach to potential heartburn, even though they know that there are over-the-counter (OTC) acid reducers that can help relieve their symptoms. In fact, according to the survey, 67% said they have experienced heartburn symptoms but chose not to take medication because they expected symptoms would go away on their own. Even among those who experience severe symptoms, 77% reported doing the same.*

Don't let heartburn interrupt the moment. If you know certain foods can trigger occasional heartburn, consider picking up an OTC acid reducer like PEPCID^® so you can enjoy a Saturday barbecue. By reducing the amount of acid in the stomach, PEPCID^® relieves heartburn and controls acid for up to 12 hours.** It works fast and lasts all day***, so you can enjoy a meal without worrying about discomfort.

Enjoy the season with a heartburn game plan

You don't have to give up your favorite foods to avoid heartburn. Using these simple tips, you can feel more prepared to enjoy the season's biggest food moments with the people you love. Before your next backyard cookout, tailgate or fall gathering, visit Pepcid.com to learn more about occasional heartburn, compare product options and find where to buy relief near you.

Use products only as directed.

*PEPCID^® commissioned an online survey with KRC Research of 3,000 U.S. adults aged 18 or over in Spring 2026, reflective of U.S. census demographics.

**Acid control does not imply symptom relief.

***Starts to work in 15-30 minutes. Lasts all day based on 8-hour symptom relief studies during the day.

The campaign features one-of-a-kind sandwich recipes as unique as the wish kids behind them. Whether your child prefers a fresh and savory sandwich like Olivia's Bright Harvest Bacon Bite, a sweet treat like Eliana's Banana Boost Super Swirl or a cheese-forward lunch like Luke's Mediterranean Magic Melt, the digital cookbook has plenty of creative recipes to try.

The spark behind the campaign is simple yet profound: Sandwiches may use the same ingredients, but no two are the same, just like wishes. It's the combination of ingredients like a smear of avocado, a surprising pop of berry jam or slices of crisp apple that takes an ordinary lunch and transforms it into an extraordinary meal.

A wish comes together in the same way. When you combine a child's imagination with care, coordination and community support, what may seem like a typical request to visit a theme park, meet a celebrity or travel to a tropical location becomes a treasured memory that has a lasting impact beyond the day the wish is granted.

"When I found out my wish was being granted, I had just gotten out of a six-week stay in the hospital and PICU," said wish kid Elizabeth, the creator of the Berries N Cream Dreamwich. "I had missed competing at cheerleading worlds and was facing a life-changing diagnosis, so having my wish granted gave me hope and something to look forward to. Being part of Make-A-Wish still reminds me of that."

Isabella, the chef behind the Jam-Packed Joywich, was inspired by her wish to give back to the community that gave her hope.

"As I got older, I discovered a love for volunteer work and working with charities," she said. "As I moved into high school, I found a career that would allow me to do that: corporate social responsibility. Now a junior in college, and after completing my internship with Make-A-Wish, I'm pursuing the dream of giving back so I can share the same hope I received with other kids and families."

A slice of hope for the back-to-school season

The partnership between Nature's Own and Make-A-Wish isn't limited to sandwiches. The bread brand has committed $500,000 to support Make-A-Wish through 2026, helping fund life-changing wishes for children with critical illnesses. The Sandwishes campaign builds on this financial support by giving families a simple way to be part of the mission by exploring wish kids' recipes and learning how they can help bring more wishes to life.

"We're grateful to Nature's Own for helping bring our wish kids' creativity to life in such a joyful, accessible way," said Leslie Motter, president and CEO of Make-A-Wish America. "Through the Sandwishes campaign, families can connect with the imagination behind each wish while helping Make-A-Wish deliver hope and joy to children with critical illnesses. Partnerships like this make it possible for us to reach more children and families with the life-changing power of a wish."

To explore more delicious wish kids' recipes that you can sample this school year and learn more about the campaign, visit NaturesOwnBread.com/Wish.

Crohn's disease (CD) is a chronic condition that affects approximately 1 million people living in the U.S.¹ Research shows that the disease has become increasingly common in the U.S. and other parts of the world, yet experts don't know why.¹

CD is a type of inflammatory bowel disease (IBD) that causes inflammation (swelling) and ulcers (sores) in the digestive tract.¹ CD accounts for approximately 40% of IBD cases.^2,3

Your digestive tract digests and moves food through your body. It includes your⁴:

• Mouth
• Esophagus (the tube that connects your mouth to your stomach)
• Stomach
• Small intestine
• Large intestine, which includes your colon, rectum and anus

What causes CD?

In CD, the body's immune system overreacts and damages healthy tissues in the digestive tract.⁵ It most often happens in the small intestine and the beginning of the large intestine. However, CD can happen in any part of the digestive tract.¹ Though experts don't know exactly what triggers CD, research shows that it may be due to a combination of immune system changes, genes and lifestyle factors.⁵

"Researchers are evaluating the safety of an investigational medicine and how well it may work in resolving or improving Crohn's disease symptoms compared to placebo in a clinical trial happening now," said Dr. Ahmed Kurdi, gastroenterologist and principal investigator at Sanford Health. "You or a loved one may be eligible to participate based on the inclusion criteria."

Join a clinical trial for CD

A clinical trial, also called a clinical study, is a type of research designed to learn more about how the body responds to investigational medicines, vaccines, or other treatments.

There is a clinical trial studying an investigational medicine for moderate to severe CD. Moderate to severe CD means symptoms happen more often or are more intense compared to mild CD, often leading to additional complications and greater impact on daily life.⁶

The goal of this trial is to learn if the investigational medicine is safe and works well to improve CD symptoms compared to a placebo.⁷ A placebo looks like the trial medicine but has no medicine in it. Using a placebo helps researchers better understand the effects of the investigational medicine.

This trial is for adults who⁷:

• Are between ages 18 and 80
• Have had CD for at least 2 months and currently have moderate to severely active CD
• Have had at least 1 of the below:
  • Have not responded well or stopped responding to at least 1 CD treatment
  • Have not tolerated their dose of corticosteroids (such as prednisone, budesonide, or beclomethasone) being reduced
  • Have not been able to tolerate taking at least 1 CD treatment

The importance of representation in clinical trials

Representation in clinical trials helps researchers gain a more complete picture of how investigational medicines work across populations. This helps support the development of safe and effective medicines for those who are most affected by the disease or condition being studied. Today, only 24% of clinical trial participants are from communities of color despite making up more than 40% of the U.S. population and facing higher burdens of many diseases.⁸

"Communities of color haven't always been equally represented or treated in healthcare," said Dr. Kurdi. "Acknowledging that history can open the door to honest conversations about clinical trial participation and provide access to research that may be relevant to their care."

More about this trial

There are more eligibility criteria for this trial. There may be risks related to participating in clinical trials. The trial doctor can discuss these with you.

Participation in clinical trials is voluntary, and participants are free to leave at any time, for any reason. Participants may or may not directly benefit from being in the clinical trial, but they will help researchers learn more about the investigational medicine and CD.

You can learn more about this clinical trial at Merck's clinical trial page.

References

1. National Institute of Diabetes and Digestive and Kidney Diseases. Definition & facts for Crohn's disease. Updated October 2025. Accessed May 1, 2026. https://www.niddk.nih.gov/health-information/digestive-diseases/crohns-disease/definition-facts
2. Crocetti E, Bergamaschi W, Russo AG. Population-based incidence and prevalence of inflammatory bowel diseases in Milan (Northern Italy), and estimates for Italy. Eur J Gastroenterol Hepatol. 2021;33(1S suppl 1):e383-e389. doi:10.1097/MEG.0000000000002107
3. Lewis JD, Parlett LE, Jonsson Funk ML, et al. Incidence, prevalence, and racial and ethnic distribution of inflammatory bowel disease in the United States. Gastroenterology. 2023;165(5):1197-1205.e2. doi:10.1053/j.gastro.2023.07.003
4. Cleveland Clinic. What is the digestive system? October 25, 2024. Accessed June 16, 2026. https://my.clevelandclinic.org/health/body/7041-digestive-system
5. Cleveland Clinic. Crohn's disease: What it is, symptoms, causes & treatment. December 4, 2023. Accessed May 1, 2026. https://my.clevelandclinic.org/health/diseases/9357-crohns-disease
6. CrohnsAndColitis.com. Crohn's disease severity and progression. Accessed July 8, 2026. https://www.crohnsandcolitis.com/crohns/severity-and-progression
7. Merck Clinical Trials. A study to evaluate the efficacy and safety of tulisokibart in participants with moderate to severe Crohn's disease. Accessed May 7, 2026. https://www.merckclinicaltrials.com/trial/nct06430801/
8. Merck. Let's Talk Trials. Accessed May 27, 2026. https://www.merckclinicaltrials.com/Lets-Talk-Trials/

These questions are especially important for people at higher risk of serious illness. Planning ahead can save valuable time, because treatments work best when started soon after symptoms first appear.

Here are three things worth doing before respiratory illness season gets underway.

1. Know what can put you at higher risk

Age matters. So do health conditions such as asthma, diabetes, heart disease, and other chronic illnesses.

Older adults are more likely to develop serious complications from COVID-19 or flu, and the risk generally rises with age. Conditions that affect the heart, lungs or immune system can also make it harder to fight an infection or recover from one.

Pregnancy can also raise the risk of complications from some respiratory illnesses. Young children can be especially vulnerable to serious complications from flu.

You don't have to sort through that risk on your own. Ask a healthcare provider what your age, medical history, pregnancy status or other circumstances mean for you before you're sick and pressed for time.

2. If you're at higher risk, don't wait

The first few days after symptoms appear can make a real difference.

Antiviral treatments are available for COVID-19 and flu. For people who are eligible, they can reduce the risk of severe illness, but the window to start treatment is short.

Flu antivirals work best when started within the first two days of illness, although starting later may still help some people. Some COVID-19 treatments must begin within five days after symptoms start, while others must begin within seven days.

If you're at higher risk and develop a fever, cough, fatigue, body aches or other symptoms, don't wait for them to get worse. Contact a healthcare provider promptly and ask whether you should be tested and whether antiviral treatment is right for you.

3. Make a plan now, while you are well

No one wants to figure out where to get care while feeling miserable. Thinking through the first steps now can make it much easier to act quickly later.

Start with the people in your household. Who may be at greater risk? Consider keeping at-home tests on hand and know how you would quickly reach your healthcare provider, a pharmacist or another source of medical care.

This is also a good time to ask a healthcare provider which COVID-19 and flu vaccines are recommended for you. Vaccination can help protect against severe illness and complications.

If you care for an older parent, a young child or someone with an underlying health condition, bring them into the plan. A short conversation now about their risk, who to call and what to do if they become sick can prevent delays later.

Viruses don't always follow the calendar, and they rarely arrive at a convenient time. Know your risk, know where you'll turn for care and act quickly when symptoms begin. Those three steps can help you avoid losing valuable time when it matters most.

CVEEP brings together public health, patient and provider organizations to share practical information and resources about respiratory illness prevention and treatment.

For more information about respiratory illness risk, prevention and treatment, visit CVEEP.org/treatments.

To help make the transition a little easier, Registered Dietitian and Nutritionist Dawn Jackson Blatner shares four simple ways to ease back into healthy habits and fuel your body for whatever the new season brings.

1. Rebuild your routine, not your personal best

After a summer of travel, vacations and shifting schedules, don't worry about picking up where you left off. Instead of chasing your previous pace or performance, Blatner recommends setting realistic weekly movement goals and focusing on consistency first.

Easing back into your routine helps you stay consistent and reduces the risk of burnout.

2. Explore mindful movement

Mindful movement is a great way to reconnect with your body as you ease back into your routine. Blatner recommends exploring low-impact workouts, such as a class at your local Club Pilates studio to help rebuild strength, flexibility, balance and posture while supporting a strong mind-body connection.

Pilates is approachable for all fitness levels and it's an easy way to ease back into regular movement while building confidence and consistency throughout the fall.

3. Pair healthy habits together

Building healthy habits doesn't have to feel overwhelming. Blatner recommends trying "habit stacking," a strategy that pairs one healthy behavior with another to help make both habits easier to maintain.

For example, schedule a nourishing breakfast after your Club Pilates class or pack a balanced snack before heading out the door. Connecting healthy habits together can help them become part of your everyday routine.

4. Fuel your recovery

Refueling after movement is just as important as the workout itself. Within 30 to 60 minutes after exercise, Blatner recommends eating a balanced meal that combines high-quality protein with wholesome carbohydrates to help replenish energy stores and support muscle recovery.

One easy way to refuel after Pilates is with this Hot Honey Egg Toast from Eggland's Best. Packed with protein and wholesome ingredients, it's a flavorful meal that helps nourish your body while getting back into your post-summer routine.

Eggland's Best eggs contain more than double the Omega-3s compared to ordinary eggs, helping reduce muscle soreness and aid in recovery after strenuous exercise. Eggland's Best eggs also contain six times more Vitamin D, promoting healthy bones and muscles. Eggland's Best eggs have 25% less saturated fat, more than double the amount of Vitamin B12 and 10 times more Vitamin E compared to ordinary eggs.

Hot Honey Egg Toast

Prep Time: 5 minutes; Cook Time: 4 minutes; Yield: 1 serving

Ingredients:

• 2 Eggland's Best eggs, large
• 1 tablespoon hot honey
• 1/4 cup shredded mozzarella cheese
• 1/2 cup chopped baby spinach
• 2 slices whole grain toast

Instructions:

1. In a non-stick skillet over low-medium heat, add honey, then top with cheese and spinach.
2. Make two little wells, crack one Eggland's Best egg into each well, cover with a lid and let cook about 4 minutes, until the eggs are set and the edges of the cheese are melted/golden.
3. Serve each egg on a slice of toast.

Find more recipe inspiration at EgglandsBest.com/recipes.

Enter the Eggland's Best x Club Pilates Sweepstakes

Eggland's Best has teamed up with Club Pilates for the second year in a row to help fans fuel their flow with better nutrition and mindful movement!

To celebrate, Eggland's Best and Club Pilates are bringing fans the "Fuel Your Flow with EB" Sweepstakes, designed to inspire healthier routines and support wellness from the inside out. Now through Oct. 20, fans can enter daily at EBFamilySweeps.com for a chance to win the Grand Prize of $5,000 to refresh their wellness routine, a 6-month single studio, Unlimited Club Pilates membership, branded swag, and a 3-month supply of Eggland's Best eggs. Weekly prize packs will also include a $250 grocery gift card, a 3-month, single studio, Unlimited Club Pilates membership, and more.

Americans aren't getting enough fiber-rich foods. According to Johns Hopkins Bloomberg School of Public Health, "Ninety to ninety-five percent of Americans fall short of recommended dietary fiber intake, consuming about 15 grams daily of the recommended 25–38 grams."

Breakfast is a missed opportunity to increase fiber intake and typical breakfast foods like frozen waffles or sugary cereal provide almost none.

Why is it important to eat fiber in the morning?

A fiber-rich breakfast sets the tone for the day, promoting stable energy, improved digestion, decreased hunger and steady blood sugar.

Eating fiber in the morning helps keep your energy levels steady because it helps keep blood sugar stable. This also decreases cravings, which is key to limiting intake of the high-sugar foods we usually crave.

You can include fiber at breakfast in a variety of ways. Consider the following ideas.

Easy high-fiber breakfast ideas

• Ezekiel Sprouted Grain Bread and Cereal
  
• Sprouting makes it easier to digest fiber, and vitamins and minerals are better absorbed.
• Breakfast idea: two slices of Ezekiel Sprouted Whole Grain bread topped with avocado and a soft-boiled egg.
• Oats
  
• This breakfast classic provides four grams of fiber in a half cup of uncooked oats (which equals one cup cooked).
• Breakfast idea: overnight oats with chia seeds, berries and a spoonful of almond butter; all these ingredients contain fiber.
• Chia seeds
  
• Two tablespoons provide 10 grams of fiber, packing a punch in a small volume of food.
• Breakfast idea: chia pudding made the night before with almond milk and topped with mango or berries.
• Berries
  
• Raspberries contain the most fiber with eight grams per cup. Strawberries provide three grams for the same amount.
• Breakfast idea: berries added to yogurt, mixed into oatmeal or blended into a smoothie.
• Flaxseed
  
• Two tablespoons have four grams of fiber plus omega-3 fatty acids. Grinding or crushing flaxseed makes it easier for the body to absorb nutrients, especially the omega-3-containing oil.
• Breakfast idea: bake seeds into flaxseed muffins, stir them into oatmeal or sprinkle them into yogurt.
• Legumes
  
• Although they're not a popular breakfast food, black beans go great with a savory meal and contain seven grams of fiber in a half cup.
• Breakfast idea: add beans to scrambled eggs or breakfast burritos on Ezekiel sprouted grain, flourless tortillas.

How to stack fiber without overhauling breakfast

To avoid feeling overwhelmed when it comes to adding fiber to your morning meal, consider these tips.

• Top your food: Start with a fiber base (such as Ezekiel sprouted grain cereal or oats) and add two fiber-rich toppings. These could be a half cup of raspberries and two tablespoons of chia seeds. You'd get a whopping 16 grams from your bowl of oatmeal alone!
• Swap foods out: Substitute one high-fiber food for a low-fiber equivalent. Exchange white toast for sprouted grain bread or flavored yogurt eaten alone for plain Greek yogurt with fruit and flaxseed.
• Blend foods together: Add a tablespoon of ground flaxseed or chia to smoothies, batters or overnight oats. You'll barely notice them while easily increasing fiber intake.
• Think ahead: Make fiber-rich breakfasts the night before. Options like chia pudding, overnight oats or fiber-rich bran muffins will be ready for you in the morning, saving you time.
• Increase slowly: One of the biggest considerations when increasing fiber is to do so slowly. Adding too much too fast can cause bloating and other GI symptoms. Add three to five grams per week until you reach your daily goal based on gender and age.

How to plan a week of high-fiber breakfasts

If you need inspiration, follow these ideas for including a variety of fiber-containing foods into your breakfast each day.

• Sunday: Cottage cheese bowl (replace blueberries with strawberries): ~7 grams fiber
• Monday: Two slices Ezekiel sprouted grain toast with half an avocado: ~11 grams fiber
• Tuesday: Overnight oats with two tablespoons flaxseed, 1/2 cup strawberries and one tablespoon almond butter: ~11 grams fiber
• Wednesday: Chia pudding with mango: ~13 grams fiber
• Thursday: Sweet potato hash with half an avocado: ~10 grams fiber
• Friday: Ezekiel Sprouted grain cereal with almond milk and half a cup blueberries: ~8 grams fiber
• Saturday: Whole wheat waffles topped with 1/2 cup blackberries and whipped cream: ~10 grams fiber

Adding fiber doesn't need to involve a major overhaul. Instead, adding fiber-containing foods like Ezekiel bread or Cereal to what you usually eat is a way to make a big difference in fiber intake.

A fiber-filled breakfast will keep you full and provide steady energy for longer periods of time. Try different options to see which ones you like best!

In the United States, 28.8 million adults live with diabetes, and heart disease is the leading cause of death. Diabetes and heart disease are closely connected, as people with diabetes are at two times the risk of developing heart disease compared to those who do not have diabetes.

As people understand more about how nutrition can benefit their health, they have found that sprouted grains benefit people who have diabetes and/or heart disease.

The sprouting process sets these grains apart, making them easier to digest. Vitamins and minerals are also more easily absorbed than in grains that have not sprouted.

Why are sprouted grains better?

• Grains are sprouted through a process where they are soaked in water and allowed to germinate. This leads to proteins and carbs being broken down, which makes vitamins and amino acids easier to digest.
• The carbohydrate content of sprouted grains changes. Starch content decreases while fiber increases. Less starch means blood sugar is less likely to spike during digestion, and higher fiber content slows down blood sugar absorption.
• The glycemic index (GI) is an indicator of how quickly blood sugar rises after eating certain foods. Low GI foods have scores of 0 to 55. This category includes foods such as apples, milk, yogurt, steel-cut oats and bran cereal. Sprouted grains fall into the low GI category generally scoring around 15, making them a blood sugar-friendly option.
• Fiber intake has also been shown to benefit heart health by decreasing low-density lipoprotein (LDL) cholesterol, lowering inflammation and promoting normal blood pressure.
• Protein also changes during the sprouting process with increases in certain amino acids due to protein breakdown. These changes contribute to making sprouted grains more easily digested.

Do studies show sprouted grains can benefit diabetes and heart disease?

While research is limited, studies have shown that consuming sprouted grains can benefit both diabetes and heart disease.

One study looking at intake of germinated brown rice among people with type 2 diabetes found they had lower levels of fasting blood sugar and insulin.

Insulin sensitivity, which is how well the body responds to insulin, is an important aspect of diabetes management. Sprouted grains are thought to improve insulin sensitivity because of their anti-inflammatory and antioxidant properties and their ability to promote steady blood sugar after eating.

The types of fat consumed make a difference in health. Omega-3 fatty acids have health benefits, and consuming them has been associated with lower rates of cardiovascular disease. Sprouted grains, such as sprouted flax seeds, provide omega-3 fatty acids.

How to incorporate sprouted grains in your diet

Consuming sprouted grains is easier than you might think. By making a few changes to your eating pattern, you can add them to your diet in a variety of ways.

• For example, at breakfast, swap white bread for a sprouted grain bread, such as Ezekiel bread.
• If you like breakfast sandwiches, opt for Ezekiel Sprouted Grain English Muffins. The sky is the limit here: You can add eggs, cheese and any kind of vegetables you like for a savory morning meal.
• Beyond bread, try sprouted pasta instead of standard white or whole wheat varieties. Balance it out with a source of protein such as meat, fish or tofu along with a vegetable for fiber.
• On Taco Tuesday, use Ezekiel Taco Size Sprouted Grain Tortillas.
• As the weather — and your grill — warm up, use Ezekiel Sprouted Grain Burger Buns and Hot Dog Buns for a healthier option.

To benefit your blood sugar and heart health, it's best to include the following components at your meals:

• A complex carbohydrate, such as sprouted grain breads, pastas or buns. Potatoes, peas, winter squash and corn also fall into this category and are considered starchy vegetables.
• A source of fiber, such as non-starchy vegetables. From broccoli to carrots to bell peppers, eat as many veggies as you'd like!
• A protein source, such as meat, fish, eggs, chickpeas or cottage cheese.
• If you're unsure how to lay out your plate, use the Diabetes Plate Method: Half your plate has non-starchy vegetables, a quarter contains carbs and a quarter contains protein.
• Choose an unsweetened beverage such as water, milk or herbal tea to go with your meal.

Sprouted grains offer benefits to people living with diabetes and heart disease. Including them in your eating pattern as part of a healthy lifestyle is a smart way to optimize nutrition.

Small swaps in your diet can make a big difference. If you are interested in trying Food For Life's products, use the Store Locator tool to find out where they are sold near you.

While Southern California, Texas, Oklahoma, and parts of central and southern Appalachia face the highest wildfire risk in October, dry vegetation, fallen leaves and seasonal winds can create conditions for fast-moving fires whose impact can still reach homes miles, even states, away. Once in your area, wildfire smoke can enter your home and affect indoor air quality. Learn how HVAC filtration and air cleaners can help reduce dangerous smoke particles indoors.

How Wildfire Smoke Affects Indoor Air Quality

Wildfire smoke doesn't stay near the flames. It can travel hundreds or even thousands of miles, settling into communities far removed from the fire itself.

What makes it particularly concerning is what it carries: microscopic particles known as PM2.5. These particles can move deep into the lungs and bloodstream, impacting breathing, heart health and overall well-being, especially for children, older adults and those with respiratory conditions.

And while heading indoors feels like the natural solution, smoke has a way of following.

It can slip through doors, windows, ductwork and even HVAC systems, quietly affecting the air you breathe every day.

Microscopic PM2.5 particles from wildfire smoke can travel unseen through the air — making their way indoors and affecting the air you breathe every day. Getty

How to Reduce Wildfire Smoke Inside Your Home

Here's the reassuring part: protecting your indoor air quality doesn't require drastic change, just the right approach. According to the EPA, HVAC filtration and air cleaners are among the most effective ways homeowners can help reduce indoor smoke particles during wildfire events. You can use the following strategies to reduce your indoor exposure:

• Close windows and doors to limit smoke from entering your home
• Avoid adding indoor pollutants, like burning candles or cooking at high heat
• Use portable air cleaners to help reduce airborne particles
• Adjust your HVAC system to recirculate indoor air instead of pulling in outside air
• Upgrade to a MERV 13 (or higher) air filter to help reduce smoke particles

These small adjustments can go a long way. For even greater impact, consider enhancing your system with advanced air purification solutions like the Lennox PureAir™ S system, which goes beyond filtration to remove smoke particles throughout your home. For guidance on choosing the right filtration or purification solution, consider working with a trusted home comfort expert like Lennox, or a local Lennox dealer.

Closing windows is a simple but effective first step, helping limit smoke from entering your home and giving your indoor air a chance to stay cleaner and more controlled. Getty

How HVAC Filtration Can Help During Wildfire Season

Wildfire seasons are becoming longer and more intense, making indoor air quality an ongoing concern, not just a seasonal one.

The good news? Homes with effective filtration and well-maintained systems consistently experience:

• Lower indoor particle levels
• Reduced smoke odors
• More consistent, comfortable living environments

Preparing your home and air systems ahead of time can help reduce health risks and keep your space comfortable when smoke arrives.

To learn more about IAQ products, find the right solution for your home and find a dealer to test your indoor air quality, visit Lennox.com.

Lennox indoor air quality solutions are built for reliable performance, long-lasting durability and energy-efficient operation, helping create cleaner air with comfort that stands the test of time. Courtesy of Lennox

"My first pregnancy was really pretty easy all along. I felt great," Strout said. "It wasn't really until late in my third trimester that I started to have severe migraines, vision disorientation and flashes of light. I knew something wasn't right."

Strout called her doctor, who advised her to go to the nearest emergency room. There, a urine test revealed she had developed preeclampsia.

What is preeclampsia?

According to March of Dimes, preeclampsia is a serious condition that can happen after the 20th week of pregnancy and affects one in 25 pregnancies in the U.S. Preeclampsia causes a sudden rise in blood pressure that can put mother and baby at risk during pregnancy, labor, delivery and even across both of their lifespans.

Strout, who had never experienced high blood pressure before, was shocked to learn she had developed the condition. Just four short days after her diagnosis, Strout returned to the hospital and experienced a 54-hour induced labor with worrying complications.

"When we finally were at a point where I was ready to start to push, my heart rate started to go up, and my son's heart rate started to go down," Strout said.

Fortunately, her medical team responded quickly. Following an emergency cesarean section, Mason Strout was born three and a half weeks early. Though Mason required surgeries for an unrelated health issue, both mother and baby fully recovered from the difficult delivery.

Seven months later, Strout became pregnant again. Given her first pregnancy, Strout's second could have been incredibly stressful. Luckily, given her history, her doctor recommended a simple preventive measure Strout hadn't known about before: low-dose aspirin.

How a low dose can provide big benefits

Studies have shown that taking low-dose aspirin during pregnancy is a safe method that may reduce the risk of preeclampsia and the potential harm it can cause to both mom and baby.

Low-dose aspirin works by improving blood flow to the uterus and may ensure that the baby gets enough oxygen and blood flow through the placenta. Because of the benefits, the U.S. Preventive Services Task Force recommend the use of low-dose aspirin (81 mg) as preventive medication between 12-28 weeks (ideally 12-16 weeks) gestation for people like Strout, who are at high or moderate risk for preeclampsia.

Spreading the word

Many expecting parents like Strout are unaware that low-dose aspirin is a proven option for a safer pregnancy for at-risk moms. To bridge this gap, March of Dimes launched the Low Dose, Big Benefits campaign™ to train healthcare and pharmacy professionals, implement quality improvement in outpatient clinics, and educate pregnant people, their families and the public.

"Low-dose aspirin can help reduce the risk of developing preeclampsia, and it all starts with getting the word out," said Kelly Ernst, Chief Impact Officer, March of Dimes. "By ensuring families know about the benefits of low-dose aspirin, I'm hopeful that we can improve outcomes for both mom and baby, giving them the best start they deserve."

Strout echoes this sentiment, explaining that having a planned delivery and a preventive measure made her second birth more controlled and less stressful than her first.

"Low-dose aspirin," Strout said. "It really helped with my second pregnancy. It allowed me to have that sense of comfort, knowing that I was taking precautions to avoid having the same symptoms that I had late term with my first pregnancy."

Ask your health care professional if you've been screened for preeclampsia and if low-dose aspirin is right for you. Visit MarchofDimes.org/LowDoseBigBenefits for more information about preeclampsia and the safe use of low-dose aspirin when prescribed by a health care professional.

• Veterans and service members experience particularly traumatic events that can lead to increased risk of suicide.
• Suicide prevention begins long before a veteran or service member is in crisis. When you recognize the warning signs and act early, you can help connect them with support before a situation escalates.
• Everyone can do their part to end veteran suicide.

For over 250 years, brave men and women have selflessly served the country to protect the freedoms we enjoy. Yet too many return carrying unseen wounds and fight their hardest battles once they return home.

The most recent Wounded Warrior Project^® (WWP) Warrior Survey found that more than 1 in 4 warriors experienced suicidal thoughts within the past year. And, according to the Department of Veterans Affairs, 17 veterans die by suicide each day.

Losing over 6,200 American heroes every single year — roughly one every 90 minutes — should not be the cost of serving the country. This cost of service has affected veterans for generations, and will continue to impact future generations, without action now.

"Service members are exposed to situations and environments that increase risk of suicide," said Lyndsay Tkach, mental and brain services director at WWP^®. "That's not exclusive to combat experience, and it's not based on the rank worn or the deployment taken. Suicide risk doesn't discriminate. It can touch any service member, veteran, or family, often in ways that are not immediately visible."

Service can be a source of purpose, pride, and lifelong strength. But for many veterans, experiences during and after service can also contribute to challenges such as physical injury, moral injury, survivor's guilt, and other risk factors associated with suicide. As a nation, each individual has a responsibility to ensure these risk factors don't lead to suicide.

A grateful nation's collective responsibility

"The focus is often on intervention, but we're often missing a critical piece of the conversation," said Tkach. "A veteran may not reach out until a crisis is already happening. To truly make an impact, we have to meet veterans where they are, before a crisis occurs, by connecting them to resources and support that protect against suicide."

True suicide prevention begins as soon as risk is present. No one person can end veteran suicide alone, but everyone can play a role in addressing its root causes and strengthening protective factors.

Together, everyone can:

Identify risk factors and warning signs early. Understanding the difference between risk factors and warning signs is an important part of preventing veteran suicide. Risk factors are the underlying challenges that can increase vulnerability over time. Isolation, health challenges like traumatic brain injury and post-traumatic stress disorder, financial strain, or difficulties adjusting after military service can all be risk factors to monitor.

On the other hand, warning signs are often more immediate, like shifts in actions or personality. Changes in mood, behavior, or risk-taking, as well as comments about being gone or planning for the future without them, can be important warning signs.

By recognizing these signs early, understanding that they can be different for everyone, and having conversations before a crisis develops, everyone can help end veteran suicide.

Have tough conversations and provide support before the breaking point. Having open, direct conversations with each other about mental health can support the shift from reactive intervention to proactive prevention.

Veterans' family members and friends often feel unsure about how to support their loved ones during challenging times. Asking direct questions about mental health or suicidal thoughts can feel like a risk. The fear of messing up can lead to inaction.

But when someone is struggling, isolation can intensify emotional pain and reinforce feelings of hopelessness. That is why having honest, compassionate conversations before a crisis develops is so important.

Here are some tips for asking a loved one about suicidal thoughts:

• Share your observations. Start by showing care and sharing what you've noticed. Statements like, "You've said..." or "I've noticed..." can open the door to an honest conversation.
• Validate their experience. Let them know their feelings are heard and understood. Simple responses such as, "That sounds overwhelming" or "That sounds really painful" can be powerful, especially coming from someone they trust.
• Ask directly. If you're concerned about suicide, use clear and direct language. Ask questions like, "Are you thinking about suicide?" or "Are you thinking about ending your life?" Avoid vague wording and create space for an honest response.
• Be prepared to listen.

Reaching out, checking in, and creating space for someone to share their experiences and thoughts can help restore a sense of safety and support. For individuals experiencing thoughts of suicide, meaningful connection and early support can serve as critical protective factors, helping them feel seen, supported, and less alone in their pain.

Suicide is complex, so take the responsibility off yourself to have all the answers, offer solutions, or try to be a therapist. The most important thing you can do is hold space to listen and validate their challenges.

Help build stronger support systems for veterans during their transition to civilian life. When service members leave the military, they're leaving behind more than a job. They're also leaving structure, stability, and camaraderie. Navigating the unpredictable nature of civilian life often leaves veterans isolated, feeling as if they've lost their purpose, and even who they are as a person. But, they don't have to face these challenges alone. A strong community of support can save lives. Access to trusted resources, meaningful connections, and a sense of belonging can make all the difference for veterans facing challenges.

You can play a part in creating suicide-safe communities by supporting and getting involved with organizations like WWP. The veterans nonprofit not only provides direct resources and support for service members, veterans, and families, but also builds more supportive communities through training and education that equips individuals with the skills needed to intervene effectively and compassionately.

The workshops help participants learn how to talk to someone about suicide, the signs to watch for, and how to develop a plan to support their immediate safety. With specialized suicide prevention training, more people in veteran communities can become advocates for suicide prevention, offering life-saving support.

"By increasing the number of individuals trained to recognize warning signs and provide effective, evidence-based prevention, intervention, and postvention support, Wounded Warrior Project is working to ensure that veterans at risk of suicide have more opportunities to interact with individuals who are informed about suicide risk," said Tkach.

Shifting from reactive to proactive prevention saves lives

Ending veteran suicide is a national responsibility, and it needs to begin now. By building proactive community support at every level, everyone can help protect the men and women who protected them.

"The most effective way to end veteran suicide is to stop waiting. We need to identify risks early, have direct and open conversations about suicide, and build strong, supportive communities for veterans to come home to," said Tkach. "The goal isn't to respond when we see the crisis, but to ensure no veteran has to face that crisis alone in the first place."

If you or someone you know needs support, immediate help is available 24/7. Call the Veteran Crisis Line at 988, then press 1 or text "HELP" to 838255.

Learn more about how Wounded Warrior Project is working to end veteran suicide.

All photos courtesy of Wounded Warrior Project.

To shine a light on a disease that often lives in the shadows, the National Alopecia Areata Foundation^® (NAAF^®) hosts the Walk For Alopecia^®, the largest fundraising and awareness campaign for alopecia areata in the world. The goal of the yearly Walk For Alopecia is to bring the community together for connection and a sense of belonging while educating the public and raising funds to advance research and support programs for those living with this disease.

This year's event on Saturday, Sept. 26, is the fourth anniversary of the walk, and to commemorate this milestone, NAAF has asked Walk For Alopecia participants to share their experiences.

Can you describe how it felt the first time you attended the Walk For Alopecia?

Lauren Nadeau, Volunteer Walk Site Leader and mother to Matthew, a National Walk For Alopecia Ambassador: The first Walk For Alopecia was incredibly emotional for our family because it was actually the first one we organized here in Boston. Seeing hundreds of people come together for this cause was powerful, but the most meaningful moment was watching Matthew meet other children and adults who looked like him and shared similar experiences.

Julia Rachel, Volunteer Walk Site Leader: I was nervous going into it. I seesawed between excitement and anxiety. It felt like I was going to be confronting the monster who had lived under my bed for years. But as soon as I arrived at the walk site and saw the crowd of people just like me, I felt my anxiety disappear, leaving only excitement and so much hope.

Harrison Goldberg, National Walk For Alopecia Ambassador: I recall being struck by the sheer number of people willing to show up to support the cause. Living with alopecia areata can be difficult; you can feel different from your peers in everyday life. But the walk reverses that experience. Instead of feeling ostracized and different from the world, you can use alopecia areata to bring people together.

Ariel Woodard-Stephens, Volunteer Walk Site Leader and National Walk For Alopecia Ambassador: I was the volunteer site leader for my first walk. I was excited to create a space for those like me. There were a lot of children in attendance, and it was like watching my younger self running around. Creating a space for children and adults with alopecia felt healing to my inner child because I never had that.

What does this year's theme "Creating Hope. Building Community. Driving Progress." mean to you?

Goldberg: For me, the theme represents three different ideas, but each is influenced by the others. Hope brings us together, community helps build our shared voice and together we can drive progress. Through events like the Walk For Alopecia and the NAAF conference, we're able to create hope for ourselves — to imagine and believe in a future where you feel proud of yourself and confident to be who you are.

Woodard-Stephens: Emphasizing hope as a source of strength can help your audience feel resilient and motivated to face challenges. And that hope translates into a desire to drive progress, such as treatment advancements with fewer side effects, health insurance coverage for expensive wigs, and increased visibility of the alopecia community, leading to fewer stares and less stigma. This focus on progress can inspire hope and confidence in future possibilities.

Thinking back to when you or your loved one was first diagnosed with alopecia areata versus being here today, how has the Walk For Alopecia impacted your own journey with acceptance?

Nadeau: The walk transformed a difficult chapter in our lives into something positive and empowering. When Matthew first lost his hair, we spent a lot of time looking for answers and trying to understand what his future might look like. The walk shifted our focus from what Matthew had lost to what he had gained. Watching him develop confidence and pride in who he is has helped our entire family move toward acceptance.

Goldberg: I was 6 years old when I was first diagnosed. I felt like a stranger in my own skin. Luckily for me, my parents found NAAF, and I eventually attended my first conference. The conference and its community propelled me to be confident and accepting of my alopecia areata. The walk reinforces the acceptance and support that I first found at the conference years ago.

How has participating in the Walk For Alopecia helped you find community?

Rachel: The walk has connected me with other people who have alopecia, not just in my state, but around the country. The more people I meet who have alopecia, the more I know our community is stronger than our disease.

Goldberg: The walk has helped me find local members of the alopecia community. It's nice to meet with someone from the community for a walk, dinner or whatever it may be.

If you had to describe the core energy or message of this walk to someone who has never participated, what would you tell them?

Nadeau: I would tell them that the Walk For Alopecia is not just a fundraiser. It's a place where people are celebrated exactly as they are and a reminder that no one has to navigate alopecia alone.

Rachel: The central theme of this walk, the lifeblood of the entire campaign, is love. There is such an outpouring of love from family and friends, and, most importantly, so much self-love. The walk helps restore that lost love and reminds you that you deserve your own kindness.

Goldberg: No matter who you are or why you're there, the Walk For Alopecia demonstrates the value and importance of being yourself. I hope that everyone who attends carries this message with them.

Woodard-Stephens: Come and experience the beauty of the community created by NAAF and its volunteers. Fall is homecoming season! If you are living with alopecia, consider the walk a chance to come home, and everyone loves a good homecoming.

If there's one thing you could tell someone else who has just been diagnosed with alopecia areata, what would it be?

Nadeau: I would tell them that it may take time to process the changes and emotions that come with alopecia, but there is an incredible community of people ready to support you. Seek out connections, ask questions and don't be afraid to share your story.

Rachel: Your diagnosis doesn't make you any less "you."

Goldberg: Try your best every day. This December, I will have had alopecia areata for 18 years. Throughout those 18 years, there have been many ups and downs, but each day is a new day. And a new day brings a new opportunity to commit to trying your best to accept your alopecia areata and love yourself for it.

Woodard-Stephens: You won't always feel this way. You are not alone. Welcome to the club. You have options.

This year, you can help create hope, build community and drive progress for everyone living with alopecia areata. Visit naaf.org/walk to join the 4th Annual Walk For Alopecia Presented by Pfizer, and help shine the brightest light on alopecia areata, raise funds and show the world it is not just hair.

"I didn't know what was going on with me," the Cleveland Guardians infielder explains. "I felt like my eyes were dry, like there was no water going through my eyes and my vision would get blurry while playing at night."

Understandably, Rocchio was concerned — vision plays an important role for athletes. In fact, in sports, nearly 80% of perceptual input is visual. "My body must be 100%, and that includes my eyes," says Rocchio.

Rocchio dealt with dry eye symptoms for years, wondering how long his problems would last. After seeking help from an eye doctor, Rocchio was diagnosed with dry eye disease. He learned that it wasn't that he wasn't making enough tears — it was that his tears were evaporating too fast, and not staying on the surface of his eyes for long enough to keep them hydrated.

Rocchio's experience is all too common — too much tear evaporation is the #1 cause of dry eye, impacting about 9 in 10 people with the condition. Dry eye caused by tear evaporation can make eyes feel tired, scratchy, irritated, rough, itchy or gritty. Eyes may sting, burn or feel painful or heavy. Other common symptoms include sensitivity to light, watery eyes or fluctuating vision, which often triggers excessive blinking.

Determined to find relief, Rocchio worked with his doctor to explore treatment options and was introduced to MIEBO^® (perfluorohexyloctane ophthalmic solution), the first and only prescription eye drop that directly targets too much tear evaporation. The exact way MIEBO works is unknown, and you should not use it if you are allergic to it.

According to Rocchio, MIEBO has helped him a lot. "The truth is MIEBO is refreshing," he says. "They're not like regular drops. They make the eye feel more moisturized."

If you are experiencing dry eye symptoms like Rocchio, don't wait — visit your eye doctor who can examine your eyes and determine a treatment plan best for you. Click HERE to learn more about Brayan Rocchio's dry eye journey.

INDICATION

MIEBO^® (perfluorohexyloctane ophthalmic solution) is used to treat the signs and symptoms of dry eye disease.

IMPORTANT SAFETY INFORMATION

• Do not use if you are allergic to MIEBO
• Remove contact lenses before using MIEBO and wait for at least 30 minutes before reinserting
• It is important to use MIEBO exactly as prescribed
• It is not known if MIEBO is safe and effective in children under the age of 18
• In pivotal trials, the most common eye side effect seen in studies was blurred vision (1% to 3% of patients reported blurred vision and eye redness)

Click here for full Prescribing Information for MIEBO.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

© 2026 Bausch + Lomb.

MBO.0218.USA.26

Lithium-ion batteries store energy more densely than traditional batteries, and they're quite powerful. However, this same power source can put your home at risk. When damaged, improperly charged or overheated, lithium-ion batteries can enter thermal runaway and spark, explode or catch on fire.

Fortunately, you have the power to protect yourself and your loved ones from these risks. All you have to do is take charge of battery safety.

Protecting your household, one step at a time

UL Research Institute's Fire Safety Research Institute understands the specific risks lithium-ion batteries present when handled incorrectly. That's why it has created Take C.H.A.R.G.E. of Battery Safety, a public safety education campaign that highlights six research-based ways to prevent lithium-ion battery fires. These steps may sound simple, but each small action you take can help create a safer home, reduce your risk of a lithium-ion battery fire, and protect your family today and tomorrow.

1. Choose certified products

Prioritize your safety by selecting lithium-ion battery-powered devices that are certified by a nationally recognized testing laboratory to ensure they meet key safety requirements.

2. Handle lithium-ion battery-powered devices with care

Always follow manufacturer guidelines and use the provided charger for lithium-ion battery-powered devices. Avoid modifying batteries or chargers and charge your devices in safe environments away from extreme temperatures, direct sunlight and flammable materials.

For larger devices, such as e-bikes, charge in a location that does not block your exit path from your home and away from sleeping areas. Ideally, you should charge e-bikes outside of your home. Refrain from overnight charging of large devices.

3. Always stay alert for warning signs

Regularly inspect devices for any signs of damage, such as swelling or punctures. Be aware of unusual sounds like hissing or popping. Watch out for excessive heat or a strange odor. White or gray wispy smoke indicates there is immediate danger of fire. If you notice any of these warning signs, stop using the device immediately.

4. Recycle devices and batteries properly

Responsibly dispose of old or damaged batteries and devices by taking them to a designated battery recycling center. Never discard batteries, chargers or battery-powered devices in regular trash bins.

5. Get out quickly if there's a fire

From the first sign of a problem, you could have less than one minute to escape a fire from a large lithium-ion battery-powered device. Know the warning signs to look and listen for and get out if you see or hear them. Follow your home fire escape plan to leave immediately, closing doors behind you as you exit and call 911.

6. Educate others on safe practices

Help protect your friends and loved ones by sharing how they can Take C.H.A.R.G.E. of Battery Safety, so that others can identify potential risks and charge safely.

Are you ready to take charge?

The power of Take C.H.A.R.G.E. is that it is an easy way to remember fire safety actions that you can adopt in your everyday life. By implementing these guidelines in your home, you can significantly reduce risk and create a safer environment for your whole family. For more information on lithium-ion battery safety, visit BatteryFireSafety.org.

Many Americans today feel more lonely and isolated, navigating increased disconnection caused by screens and social media, plus cultural shifts that began during COVID. Nearly half of Americans (44%) say there's no local coffee shop, bar, restaurant or park they visit regularly, and only 1 in 4 who live near potential gathering spots go there weekly.

Survey data shows that neighborhoods with multiple third places report higher levels of sociability. People who interact with neighbors at regular community spots are more likely to feel a sense of connection in their communities. Nearly half the residents in those communities report talking with someone they didn't know well at least once monthly, according to the American Community Life Survey. That's nearly twice as high as those living in areas without many third places.

These third places improve neighborhood cohesion and give people a reason to cross paths with those from different walks of life. Downtowns are one of the clearest examples of this in action. A thriving main street is a cluster of third places. The coffee shop, the bookstore, the diner, the plaza that hosts festivals. These main streets give people a reason to linger, run into a neighbor or strike up a conversation.

Today, states like Michigan are supporting efforts to nurture and create these crucial spaces and downtowns.

Community revitalization drives impact

Revitalization projects often showcase their environmental or safety benefits first, but their effect on local businesses is just as significant and often harder to quantify. Creating third places pays off not only in residents' health and quality of life but also in increased foot traffic and local reactivation.

Because community development is one of the clearest paths to creating more third places and opportunities for human connection, the Michigan Economic Development Corporation (MEDC) offers numerous programs and grants toward this goal that support the unique vision of each community and empower local residents to design and implement solutions that build vibrant, diverse and resilient downtowns.

Creating opportunities for main street

Across Michigan, 24 communities are working through the Michigan Main Street program to revive their commercial districts, and the results show up in both foot traffic and investment dollars. Downtown Lansing has welcomed 116 new businesses and over $123 million in private investment since 2010. Grand Haven has drawn nearly $30 million in private investment and 110 new businesses since 2005. And in Howell, a downtown revitalization effort logged more than 62,000 volunteer hours and earned recognition as USA Today's Best Main Street in 2024.

The results extend well beyond balance sheets. When a downtown becomes a place worth visiting again, residents show up, filling storefronts and connecting with one another.

Building up main street businesses

Small businesses are often what turn a storefront into a third place, the coffee shop or bakery where people linger, not just transact. The MEDC's Match on Main program provides reimbursement-based grant funding of up to $25,000 per project to support new and expanding place-based small businesses.

Doozers, a popular bakery in downtown Ishpeming, restored a space in the historic Gossard Building with the support of a Match on Main grant, turning a home-based cookie-making venture into a bustling spot for people of all ages to hang out and enjoy sweet treats, complete with a kids' play area.

"It's nice having a third space," said the bakery's owner Claire Morgan-Heredia. "When I grew up, I went to the library six days a week and just hung out there or a coffee shop. We wanted to add to the community with our space. A variety of third spaces is good, so that the community foundation remains strong."

Community spaces as third places

Not every third place is a business. Some are simply public: a park bench, a plaza, a farmers market stall. The Public Spaces Community Places program, created in partnership with the Michigan Municipal League, matches community crowdfunding campaigns dollar-for-dollar up to $50,000 for projects like parks, plazas, markets and other public gathering spaces. The match kicks in only after the community has met the project's fundraising goal.

Since 2014, this program has:

• Helped fund 421 projects across Michigan, backed by over 77,000 community members.
• Crowdfunded more than $16.9 million, leading to $14.7 million in matched funding.
• Created or redeveloped 25.9 million square feet of public spaces.

In St. Johns, the Fantasy Forest crowdfunding project transformed a beloved aging playground to be universally accessible, providing freedom of play to all children and families. Meanwhile, in Alpena, crowdfunding for the Besser Museum's Discover Northeast Michigan History Exhibit turned an outdated exhibit space into an experience that takes visitors from the Big Bang to Big Industry, providing opportunities to learn about Northeast Michigan's heritage in a family-friendly environment.

Through programs like Public Spaces Community Places, communities and the MEDC are equally invested in creating, improving and transforming spaces for all to enjoy.

With investments like these, states like Michigan are helping to support more opportunities for community connection and business development. Learn more about ways revitalization projects can support thriving communities through third places at MichiganBusiness.org.

The $5 billion ketamine therapy market is projected to nearly triple over the next decade, and the American Society of Anesthesiologists (ASA) is calling for stronger patient protections amid concerns that safety standards and oversight are not keeping pace. ASA urges patients to ask how the drug will be prescribed, who will oversee their care, and what safety and monitoring protocols will be in place.

Ketamine is approved by the U.S. Food and Drug Administration (FDA) as an anesthetic, but its use for mental health conditions is off-label. A related drug, esketamine, is FDA-approved for certain forms of depression and must be administered in a certified healthcare setting.

Because ketamine can affect breathing, heart rate and blood pressure and carries a risk of misuse, it should only be prescribed as part of a comprehensive treatment plan with medical supervision. Last year, a 41-year-old New York woman seeking relief from depression died after being prescribed at-home ketamine through a telehealth company — even though she had reported taking Xanax, a combination the FDA warns can dangerously suppress breathing.

"For decades, anesthesiologists have safely administered ketamine in hospitals and other medical settings where patients are carefully monitored, and we have grave concerns about home delivery and unsupervised use of ketamine," said ASA President Patrick Giam, M.D., FASA. "You can move very quickly from feeling relaxed to becoming deeply sedated, and without proper monitoring and supervision, that can become dangerous."

What safe ketamine care requires

Ketamine can cause serious side effects requiring prompt medical intervention. That is why it matters where treatment is provided and whether qualified medical professionals are available if something goes wrong. For ketamine given by IV or injection, ASA guidance recommends that treatment should only be provided in a monitored medical setting under the supervision of a physician who is immediately available, familiar with ketamine's effects and prepared to respond to complications. Appropriate monitoring and emergency equipment should also be readily available.

However, some patients receive prescriptions after virtual visits and take ketamine at home, typically as a tablet or lozenge that dissolves under the tongue, without a trained healthcare professional to monitor their breathing, heart rate or level of consciousness.

"You can go from a short online screening to receiving a powerful anesthetic at home," said Dr. Giam. "If something goes wrong, there may be no one there trained to respond. In the hospital, we have strict protocols to account for every milligram of ketamine administered, yet ketamine used at home is subject to far less scrutiny. Patients need appropriate safeguards wherever they receive treatment."

Lawmakers and policymakers in some states, including Texas, are considering stricter regulations, and federal officials have stepped up scrutiny of online ketamine providers and unapproved ketamine products.

What to ask before treatment

Before starting therapy, your healthcare professional should review your medical history, medications and overall health to determine whether ketamine is appropriate for you. Follow-up appointments are also important to monitor your response, adjust care if needed and identify side effects or complications.

If you're considering ketamine therapy, ask questions before treatment begins so you can make a safer, more informed decision:

• Who will evaluate whether ketamine is appropriate for me?
• Will I have an in-person medical evaluation before treatment begins?
• Who will oversee and monitor me during treatment?
• What safety measures and emergency procedures are in place if I have a serious reaction?
• How could ketamine interact with my current medications or medical conditions?
• How often will I have follow-up appointments, and who should I contact if I experience problems after treatment?

Be sure to tell your healthcare professional about all prescription and over-the-counter medications, dietary supplements, alcohol, cannabis and other substances you use. Some combinations can increase the risk of dangerous side effects or make ketamine unsafe.

For more information about ketamine, visit https://madeforthismoment.asahq.org/pain-management/ketamine/.

• Proper ventilation is critical for the comfort and health of residents in multifamily constructions.
• Builders and contractors should carefully consider ways to improve airflow and indoor air quality without overcomplicating construction and installation.
• The Panasonic WhisperFresh line meets the needs of builders and residents.

When it comes to single-family and multifamily construction, ventilation cannot be overlooked. Without proper ventilation, individual units, common areas and other spaces in the building can become stale, hot and humid. Considering that Americans spend approximately 90% of their time indoors, proper ventilation is one of the cornerstones of the success of a high-density residential building project.

For builders and contractors, strategies that optimize airflow and indoor air quality (IAQ) can make a huge difference in residents' comfort and health as well as a building's long-term performance. Here are five key ways developers can improve airflow across every unit of a multifamily project.

Prioritize consistent fresh-air delivery

Achieving balanced airflow in every unit of a multifamily building is critical for the comfort of all residents. When ventilation is uneven, you'll end up with some units starved of fresh air and others overventilated, leading to discomfort and inconsistent air quality across the property.

To ensure building residents receive consistent fresh air in their units, builders and contractors should consider sourcing continuous-supply fans with precise cubic feet per minute (CFM) control. This feature ensures that fresh, outside air is delivered directly to each unit, maintaining consistent IAQ from the ground floor to the penthouse.

Design with tighter building envelopes in mind

Modern buildings are being built tighter than ever, improving energy efficiency and reducing air leakage. However, that tight envelope also means that fresh air cannot enter the building through cracks and gaps in walls and windows, leaving residents breathing stale air.

Without a well-designed mechanical air supply, you risk not only residents' comfort but also code compliance. To complement the tightness of modern buildings and deliver the comfort and IAQ residents expect, look for supply fans designed with ASHRAE 62.2 code compliance in mind from the start.

Another detail to consider is humidity. Left unchecked, trapped moisture encourages mold growth, compromising residents' IAQ and building integrity. This is of particular concern in hot, humid climates like Texas, the Gulf Coast and California, where climate control drives code compliance and comfort. Prioritize ventilation solutions that deliver enhanced climate-control performance with humidity and temperature sensing.

Don't overlook noise control

One of the primary reasons occupants tamper with or turn off mechanical ventilation systems is operational noise. It's not enough for a fan to perform well. Fans that operate quietly are essential in residential environments where bedrooms and living spaces sit in close proximity to mechanical equipment.

Contractors should prioritize supply fan models rated for ultralow sone levels, less than 1 sone. That's quieter than even a running fridge. Installing quiet equipment protects indoor comfort, ensures residents leave systems running as designed and minimizes noise complaints post-turnover.

Plan for flexibility and scalability

Multifamily developments and single-family homes vary widely in layout and size, not just building by building. A single project might feature a mix of studio apartments, three-bedroom townhomes, in-law suites and sprawling corner units. Instead of sourcing different fan models to accommodate multiple layouts and unit sizes, choose flexible, scalable ventilation systems.

When sourcing supply ventilation systems, make sure the models you're considering offer versatile mounting options so that you can place the fan unit horizontally or vertically on a wall or ceiling. Also, look for models with simplified electrical integration so you can install them without worrying about proprietary wiring requirements. Combined, these features will enable easier installation in high-volume multifamily construction, regardless of size or layout.

Choose solutions built for long-term performance

After a building is finished and the residents have moved in, performing frequent maintenance in individual units can be challenging, disruptive and ultimately costly. That's why choosing durable, easy-to-maintain ventilation is crucial to the long-term performance of any multifamily building.

Look for options with features that can reduce downtime and operating costs over the life of the building. For example, supply fans that feature access doors provide residents with easy filter access without requiring a service call. Choosing a model that uses a standard filter also simplifies the process for residents and building owners today and down the line.

Sourcing for success

Finding fresh-air mechanical ventilation systems for multifamily projects doesn't have to be difficult. When searching for solutions that meet the above criteria, consider models from the Panasonic WhisperFresh^® line.

The line includes three ventilation solutions — the original WhisperFresh^® Select, as well as two new additions to the family: WhisperFresh^® and WhisperFresh^® Plus. All three models offer simplified compliance thanks to built-in FID displays, ASHRAE 62.2 Support, ENERGY STAR^® certification and HVI certification. The line is also designed for easy installation, featuring flexible mounting options, a simplified hardwired design, a paintable access door and standard filters. And as the name suggests, these ventilation solutions are whisper-quiet, operating at less than 0.3 sones.

For builders seeking climate performance, the Plus and Select models include humidity and temperature sensing. The captured real-time environmental data gives builders performance visibility and control to meet evolving codes and residents' expectations.

"Our expansion of the WhisperFresh line was done with builders, contractors and multifamily developers in mind," said Leon van Oostende, Group Sales Manager at Panasonic Eco Systems. "And it couldn't have come at a better time. Across the country, energy codes are tightening, and ventilation requirements are becoming more complex than ever. With our three-tiered platform, builders can find the code-compliant model that best fits their project needs, from entry-level to climate-adaptive options."

For more information about Panasonic indoor air quality solutions, visit: https://iaq.na.panasonic.com/.

• A Centers for Medicare & Medicaid Services (CMS) program creates an access pathway for eligible Medicare Part D patients who meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.
• Find five things to know and questions to ask your healthcare provider.
• Obesity is a chronic disease, and it is never too late to ask for support.

Obesity is a chronic disease, similar to heart disease or high blood pressure, and for some people, diet and exercise alone may not be enough.

Until now, weight management medications have not been broadly covered by Medicare even though about two in five U.S. adults aged 65 and older are living with obesity.

Now, a Centers for Medicare & Medicaid Services (CMS) program called the Medicare GLP-1 Bridge program creates an access pathway for eligible Medicare Part D patients who meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Terms apply. Eligibility based on Medicare GLP-1 Bridge Clinical Criteria. Prescription required. Talk to your doctor to learn more.

"It can be frustrating when treatments for obesity aren't covered like other chronic conditions," said Deb, a patient. "Seeing more options open up for those living with obesity — and knowing there may finally be a way to get access through Medicare Part D — feels like a step in the right direction."

If you or someone you care for has been managing obesity, here are five things to know about the Medicare GLP-1 Bridge program and tips for talking with your healthcare provider.

1. What is the Medicare GLP-1 Bridge program and what does it mean for you?

Medicare GLP-1 Bridge is a CMS program that creates a coverage pathway for eligible Medicare Part D patients who are living with obesity and meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

This is a meaningful milestone. Expanding coverage through the Medicare GLP-1 Bridge program reflects what Lilly believes is a broader shift in how obesity is understood — not as a lifestyle choice, but as a complex, potentially treatable medical condition.

Eligible Medicare Part D patients should talk with their healthcare provider about what it could mean for them and the next steps that may be required.

2. How do you find out if you are eligible for the Medicare GLP-1 Bridge program?

You may be eligible if you have a valid prescription, have Medicare Part D drug coverage and meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Your healthcare provider can help determine whether a prescription obesity management medication may be right for you. They or your pharmacist can also explain coverage requirements and submit required documentation such as prior authorization.

3. Which Lilly FDA-approved obesity medicines are included?

Two of Lilly's obesity medicines are included in the Medicare GLP-1 Bridge program:

Foundayo™ (orforglipron), the only GLP-1 pill that can be taken any time of day — no planning around food or drink.*

• What is Foundayo? Foundayo is a prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off. Foundayo should not be used with other GLP-1 receptor agonist medicines. It is not known if Foundayo is safe and effective for use in children. Please see Indications and Safety Summary with Warnings for Foundayo below.
• Click here to learn more about treatment with Foundayo.
• *Swallow tablets whole. Do not break, crush or chew the tablet. If you miss a dose, take it as soon as possible. Do not take more than 1 tablet per day. Foundayo is taken orally.

Foundayo Select Safety Information

Warning: Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, medicines that work like Foundayo caused thyroid tumors, including thyroid cancer. It is not known if Foundayo will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not take Foundayo if you or any of your family have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Zepbound^® (tirzepatide), the most prescribed branded injectable weight-management medicine.*

• What is Zepbound? Zepbound is an injectable prescription medicine that may help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off, along with a reduced-calorie diet and increased physical activity. Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines. It is not known if Zepbound is safe and effective for use in children. Please see Indications and Safety Summary with Warnings for Zepbound below.
• Click to learn more about treatment with Zepbound.
• *Based on IQVIA^® National Prescription Audit Data, representing 94% of US prescription data as of January 14, 2025.

Zepbound Select Safety Information

Warning: Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats, Zepbound and medicines that work like Zepbound caused thyroid tumors, including thyroid cancer. It is not known if Zepbound will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not take Zepbound if you or any of your family have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Other weight management medications are also covered under the program. Coverage began on July 1, 2026, for new and existing patients and will run through December 31, 2027.

4. How much do Foundayo (orforglipron) and Zepbound (tirzepatide) cost through the program?

Medicare Part D patients may be eligible for Foundayo or Zepbound for no more than $50 per month for weight management if they meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Terms apply. For eligible Medicare Part D patients with Foundayo or Zepbound prescription for weight management. Not a guarantee of coverage. Eligibility based on Medicare GLP-1 Bridge Clinical Criteria. Talk to your doctor to learn more.

To learn more, visit www.lilly.com/lillydirect/medicare. Patients can also talk with their healthcare providers about whether they qualify or refer to https://www.medicare.gov/coverage/weight-loss-drugs.

5. What should Medicare Part D patients ask their healthcare provider?

Consider asking your healthcare provider the following questions:

• Am I eligible for the Medicare GLP-1 Bridge program?
• Could a prescription obesity medicine be right for me?
• What coverage or approval steps may be required?
• Which FDA-approved treatment options best fit my health needs and lifestyle?
• How can I make sure I am accessing medicine through appropriate, regulated channels?

Obesity is a chronic disease, and it is never too late to ask for support. To learn more, visit www.lilly.com/lillydirect/medicare.

INDICATION AND SAFETY SUMMARY WITH WARNINGS FOR FOUNDAYO
Foundayo™ (fown-DAY-oh) is a prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off.

• Foundayo should not be used with other GLP-1 receptor agonist medicines.
• It is not known if Foundayo is safe and effective for use in children.

Warnings – Foundayo may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

• Do not use Foundayo if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
• Do not use Foundayo if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use Foundayo if you have had a serious allergic reaction to orforglipron or any of the ingredients in Foundayo.

Foundayo may cause serious side effects, including:

Inflammation of the pancreas (pancreatitis). Stop taking Foundayo and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting. Sometimes you may feel the pain from your abdomen to your back.

Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Foundayo. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away.

Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Foundayo with medicines that can cause low blood sugar, such as an insulin or sulfonylurea. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness, or feeling jittery.

Serious allergic reactions. Stop using Foundayo and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or very rapid heartbeat.

Changes in vision in patients with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Foundayo.

Gallbladder problems. Gallbladder problems have happened in some people who use Foundayo. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), or clay-colored stools.

Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Foundayo may increase the chance of food getting into your lungs during surgery or other procedures. Tell your healthcare providers that you are taking Foundayo before you are scheduled to have surgery or other procedures.

Common side effects
The most common side effects of Foundayo include nausea, constipation, diarrhea, vomiting, indigestion, stomach (abdominal) pain, headache, swollen belly, feeling tired, belching, heartburn, gas, and hair loss. These are not all the possible side effects of Foundayo. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before taking Foundayo

• Tell your healthcare provider about all the medicines you take. Foundayo may affect the way some medicines work, and some medicines may affect the way Foundayo works.
• Pregnancy Exposure Registry: There will be a pregnancy exposure registry for women who have taken Foundayo during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry, or you may contact Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979).
• If you take birth control pills by mouth, talk to your healthcare provider before you take Foundayo. Birth control pills may not work as well while taking Foundayo. Your healthcare provider may recommend another type of birth control for 30 days after starting Foundayo and for 30 days after each dose increase of Foundayo.
• Talk to your healthcare provider about low blood sugar and how to manage it. Tell your healthcare provider if you are taking medicines to treat diabetes including an insulin or sulfonylurea.

Review these questions with your healthcare provider:

• Do you have other medical conditions, including problems with your pancreas or kidneys, or severe problems with your liver, severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
• Do you have a history of diabetic retinopathy?
• Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
• Are you pregnant or plan to become pregnant? Foundayo may harm your unborn baby.
• Are you breastfeeding or plan to breastfeed? Breastfeeding is not recommended during treatment with Foundayo.
• Do you take any other prescriptions or over-the-counter medicines, vitamins, or herbal supplements?

How to take

• Take Foundayo exactly as your healthcare provider tells you to.
• Use Foundayo with a reduced-calorie diet and increased physical activity.
• Take Foundayo by mouth 1 time each day, with or without food.
• Swallow tablets whole. Do not break, crush, or chew the tablet.
• If you miss a dose, take it as soon as possible. Do not take 2 doses of Foundayo in the same day.
• Do not take more than 1 tablet per day.
• If you miss taking Foundayo for 7 or more days in a row, call your healthcare provider to talk about how to restart your treatment.
• If you take too much Foundayo, call your healthcare provider or Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

Learn more
Foundayo is a prescription medicine available in 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg, or 17.2 mg oral tablets. For more information, call 1-800-545-5979 or go to foundayo.lilly.com.

This summary provides basic information about Foundayo but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Foundayo and how to take it. Your doctor is the best person to help you decide if Foundayo is right for you.

OG CON BS APR2026

Foundayo^™ is a trademark of Eli Lilly and Company.

INDICATIONS AND SAFETY SUMMARY WITH WARNINGS FOR ZEPBOUND

Zepbound^® (ZEHP-bownd) is an injectable prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with:

• obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off.
• moderate-to-severe obstructive sleep apnea (OSA) and obesity to improve their OSA.

Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines. It is not known if Zepbound is safe and effective for use in children.

Warnings - Zepbound may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

• Do not use Zepbound if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
• Do not use Zepbound if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use Zepbound if you have had a serious allergic reaction to tirzepatide or any of the ingredients in Zepbound.

KwikPen^®: Do not share your KwikPen with other people, even if the pen needle has been changed. You may give other people a serious infection or get a serious infection from them.

Zepbound may cause serious side effects, including:

Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Zepbound. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away.

Gallbladder problems. Gallbladder problems have happened in some people who use Zepbound. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), or clay-colored stools.

Inflammation of the pancreas (pancreatitis). Stop using Zepbound and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting. You may feel the pain from your abdomen to your back.

Serious allergic reactions. Stop using Zepbound and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or very rapid heartbeat.

Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Zepbound with medicines that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness or feeling jittery.

Changes in vision in patients with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Zepbound.

Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Zepbound may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Zepbound before you are scheduled to have surgery or other procedures.

Common side effects

The most common side effects of Zepbound include nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching, hair loss, and heartburn. These are not all the possible side effects of Zepbound. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using Zepbound

• Your healthcare provider should show you how to use Zepbound before you use it for the first time.
• Talk to your healthcare provider about low blood sugar and how to manage it. Tell your healthcare provider if you are taking medicines to treat diabetes including an insulin or sulfonylurea.
• If you take birth control pills by mouth, talk to your healthcare provider before you use Zepbound. Birth control pills may not work as well while using Zepbound. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Zepbound and for 4 weeks after each increase in your dose of Zepbound.

Review these questions with your healthcare provider:

• Do you have other medical conditions, including problems with your pancreas, or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
• Do you take diabetes medicines, such as insulin or sulfonylureas?
• Do you have a history of diabetic retinopathy?
• Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
• Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?
• Are you pregnant, plan to become pregnant, breastfeeding, or plan to breastfeed? Zepbound may harm your unborn baby. Tell your healthcare provider if you become pregnant while using Zepbound. Zepbound may pass into your breast milk. You should talk with your healthcare provider about the best way to feed your baby while using Zepbound.
  
  

• Pregnancy Exposure Registry: There will be a pregnancy exposure registry for women who have taken Zepbound during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry, or you may contact Lilly at 1-800-LillyRx (1-800-545-5979).

How to take

• Read the Instructions for Use that come with Zepbound.
• Use Zepbound exactly as your healthcare provider says.
• Use Zepbound with a reduced-calorie diet and increased physical activity.
• Inject Zepbound under the skin (subcutaneously) of your stomach (abdomen), thigh, or have another person inject in the back of the upper arm. Do not inject ZEPBOUND into a muscle (intramuscularly) or vein (intravenously).
• Use Zepbound 1 time each week, at any time of the day.
• Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection.

If you take too much Zepbound, call your healthcare provider, call the Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

Zepbound is approved as a 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg injection.

Learn more

Zepbound is a prescription medicine. For more information, call 1-800-LillyRx (1-800-545-5979) or go to www.zepbound.lilly.com.

This summary provides basic information about Zepbound but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Zepbound and how to take it. Your healthcare provider is the best person to help you decide if Zepbound is right for you.

ZP CON BS 25FEB2026

Zepbound^®, its delivery device base and KwikPen^® are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

CMAT-30875 08/2026 © Lilly USA, LLC 2026. All rights reserved.

What she and many others have learned is that obesity is a chronic disease, similar to heart disease or high blood pressure, and for some people, diet and exercise alone may not be enough. That reality impacts about two in five Americans age 65 and older who live with obesity.

For many Americans, weight management medications have not been broadly covered by Medicare. Now, a Centers for Medicare & Medicaid Services (CMS) program called the Medicare GLP-1 Bridge program creates an access pathway for eligible Medicare Part D patients who meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Terms apply. Eligibility based on Medicare GLP-1 Bridge Clinical Criteria. Prescription required. Talk to your doctor to learn more.

"It can be frustrating when treatments for obesity aren't covered like other chronic conditions," said Deb, a patient. "Seeing more options open up for those living with obesity — and knowing there may finally be a way to get access through Medicare Part D — feels like a step in the right direction."

If you or someone you care for has been managing obesity, here are five things to know about the Medicare GLP-1 Bridge program and tips for talking with your healthcare provider.

1. What is the Medicare GLP-1 Bridge program?

Medicare GLP-1 Bridge is a CMS program that creates a coverage pathway for eligible Medicare Part D patients who are living with obesity and meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

This is a meaningful milestone. Expanding coverage through the Medicare GLP-1 Bridge program reflects what Lilly believes is a broader shift in how obesity is understood — not as a lifestyle choice, but as a complex, potentially treatable medical condition.

Eligible Medicare Part D patients should talk with their healthcare provider about what it could mean for them and the next steps that may be required.

2. Who may be eligible for the Medicare GLP-1 Bridge program?

You may be eligible if you have a valid prescription, have Medicare Part D drug coverage and meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Your healthcare provider can help determine whether a prescription obesity management medication may be right for you. They or your pharmacist can also explain coverage requirements and submit required documentation such as prior authorization.

3. Which Lilly FDA-approved obesity medicines are included?

Two of Lilly's obesity medications are included in the Medicare GLP-1 Bridge program:

Foundayo™ (orforglipron), the only GLP-1 pill that can be taken any time of day — no planning around food or drink.*

• What is Foundayo? Foundayo is a prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off. Foundayo should not be used with other GLP-1 receptor agonist medicines. It is not known if Foundayo is safe and effective for use in children. Please see Indications and Safety Summary with Warnings for Foundayo below.
• Click here to learn more about treatment with Foundayo.
• *Swallow tablets whole. Do not break, crush or chew the tablet. If you miss a dose, take it as soon as possible. Do not take more than 1 tablet per day. Foundayo is taken orally.

Foundayo Select Safety Information

Warning: Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rodents, medicines that work like Foundayo caused thyroid tumors, including thyroid cancer. It is not known if Foundayo will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not take Foundayo if you or any of your family have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Zepbound^® (tirzepatide), the most prescribed branded injectable weight-management medicine.*

• What is Zepbound? Zepbound is an injectable prescription medicine that may help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off, along with a reduced-calorie diet and increased physical activity. Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines. It is not known if Zepbound is safe and effective for use in children. Please see Indications and Safety Summary with Warnings for Zepbound below.
• Click to learn more about treatment with Zepbound.
• *Based on IQVIA^® National Prescription Audit Data, representing 94% of US prescription data as of January 14, 2025.

Zepbound Select Safety Information

Warning: Tell your healthcare provider if you get a lump or swelling in your neck, hoarseness, trouble swallowing, or shortness of breath. These may be symptoms of thyroid cancer. In studies with rats, Zepbound and medicines that work like Zepbound caused thyroid tumors, including thyroid cancer. It is not known if Zepbound will cause thyroid tumors, or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. Do not take Zepbound if you or any of your family have ever had MTC or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Other weight management medications are also covered under the program. Coverage began on July 1, 2026, for new and existing patients and will run through December 31, 2027.

4. How much do Foundayo (orforglipron) and Zepbound (tirzepatide) cost through the program?

Medicare Part D patients may be eligible for Foundayo or Zepbound for no more than $50 per month for weight management if they meet the Medicare GLP-1 Bridge Clinical Criteria and other CMS eligibility requirements.

Terms apply. For eligible Medicare Part D patients with Foundayo or Zepbound prescription for weight management. Not a guarantee of coverage. Eligibility based on Medicare GLP-1 Bridge Clinical Criteria. Talk to your doctor to learn more.

To learn more, visit www.lilly.com/lillydirect/medicare. Patients can also talk with their healthcare providers about whether they qualify or refer to https://www.medicare.gov/coverage/weight-loss-drugs.

5. What should Medicare Part D patients ask their healthcare provider?

Consider asking your healthcare provider:

• Am I eligible for the Medicare GLP-1 Bridge program?
• Could a prescription obesity medicine be right for me?
• What coverage or approval steps may be required?
• Which FDA-approved treatment options best fit my health needs and lifestyle?
• How can I make sure I am accessing medicine through appropriate, regulated channels?

Obesity is a chronic disease, and it is never too late to ask for support. To learn more, visit www.lilly.com/lillydirect/medicare.

INDICATION AND SAFETY SUMMARY WITH WARNINGS FOR FOUNDAYO
Foundayo™ (fown-DAY-oh) is a prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off.

• Foundayo should not be used with other GLP-1 receptor agonist medicines.
• It is not known if Foundayo is safe and effective for use in children.

Warnings – Foundayo may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

• Do not use Foundayo if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
• Do not use Foundayo if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use Foundayo if you have had a serious allergic reaction to orforglipron or any of the ingredients in Foundayo.

Foundayo may cause serious side effects, including:

Inflammation of the pancreas (pancreatitis). Stop taking Foundayo and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting. Sometimes you may feel the pain from your abdomen to your back.

Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Foundayo. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away.

Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Foundayo with medicines that can cause low blood sugar, such as an insulin or sulfonylurea. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness, or feeling jittery.

Serious allergic reactions. Stop using Foundayo and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or very rapid heartbeat.

Changes in vision in patients with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Foundayo.

Gallbladder problems. Gallbladder problems have happened in some people who use Foundayo. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), or clay-colored stools.

Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Foundayo may increase the chance of food getting into your lungs during surgery or other procedures. Tell your healthcare providers that you are taking Foundayo before you are scheduled to have surgery or other procedures.

Common side effects
The most common side effects of Foundayo include nausea, constipation, diarrhea, vomiting, indigestion, stomach (abdominal) pain, headache, swollen belly, feeling tired, belching, heartburn, gas, and hair loss. These are not all the possible side effects of Foundayo. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before taking Foundayo

• Tell your healthcare provider about all the medicines you take. Foundayo may affect the way some medicines work, and some medicines may affect the way Foundayo works.
• Pregnancy Exposure Registry: There will be a pregnancy exposure registry for women who have taken Foundayo during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry, or you may contact Eli Lilly and Company at 1-800-LillyRx (1-800-545-5979).
• If you take birth control pills by mouth, talk to your healthcare provider before you take Foundayo. Birth control pills may not work as well while taking Foundayo. Your healthcare provider may recommend another type of birth control for 30 days after starting Foundayo and for 30 days after each dose increase of Foundayo.
• Talk to your healthcare provider about low blood sugar and how to manage it. Tell your healthcare provider if you are taking medicines to treat diabetes including an insulin or sulfonylurea.

Review these questions with your healthcare provider:

• Do you have other medical conditions, including problems with your pancreas or kidneys, or severe problems with your liver, severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
• Do you have a history of diabetic retinopathy?
• Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
• Are you pregnant or plan to become pregnant? Foundayo may harm your unborn baby.
• Are you breastfeeding or plan to breastfeed? Breastfeeding is not recommended during treatment with Foundayo.
• Do you take any other prescriptions or over-the-counter medicines, vitamins, or herbal supplements?

How to take

• Take Foundayo exactly as your healthcare provider tells you to.
• Use Foundayo with a reduced-calorie diet and increased physical activity.
• Take Foundayo by mouth 1 time each day, with or without food.
• Swallow tablets whole. Do not break, crush, or chew the tablet.
• If you miss a dose, take it as soon as possible. Do not take 2 doses of Foundayo in the same day.
• Do not take more than 1 tablet per day.
• If you miss taking Foundayo for 7 or more days in a row, call your healthcare provider to talk about how to restart your treatment.
• If you take too much Foundayo, call your healthcare provider or Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

Learn more
Foundayo is a prescription medicine available in 0.8 mg, 2.5 mg, 5.5 mg, 9 mg, 14.5 mg, or 17.2 mg oral tablets. For more information, call 1-800-545-5979 or go to foundayo.lilly.com.

This summary provides basic information about Foundayo but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your doctor. Be sure to talk to your doctor or other healthcare provider about Foundayo and how to take it. Your doctor is the best person to help you decide if Foundayo is right for you.

OG CON BS APR2026

Foundayo^™ is a trademark of Eli Lilly and Company.

INDICATIONS AND SAFETY SUMMARY WITH WARNINGS FOR ZEPBOUND

Zepbound^® (ZEHP-bownd) is an injectable prescription medicine used with a reduced-calorie diet and increased physical activity to help adults with:

• obesity, or some adults with overweight who also have weight-related medical problems, to lose excess body weight and keep the weight off.

• moderate-to-severe obstructive sleep apnea (OSA) and obesity to improve their OSA.

Zepbound contains tirzepatide and should not be used with other tirzepatide-containing products or any GLP-1 receptor agonist medicines. It is not known if Zepbound is safe and effective for use in children.

Warnings - Zepbound may cause tumors in the thyroid, including thyroid cancer. Watch for possible symptoms, such as a lump or swelling in the neck, hoarseness, trouble swallowing, or shortness of breath. If you have any of these symptoms, tell your healthcare provider.

• Do not use Zepbound if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC).
• Do not use Zepbound if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
• Do not use Zepbound if you have had a serious allergic reaction to tirzepatide or any of the ingredients in Zepbound.

KwikPen^®: Do not share your KwikPen with other people, even if the pen needle has been changed. You may give other people a serious infection or get a serious infection from them.

Zepbound may cause serious side effects, including:

Severe stomach problems. Stomach problems, sometimes severe, have been reported in people who use Zepbound. Tell your healthcare provider if you have stomach problems that are severe or will not go away.

Dehydration leading to kidney problems. Diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration), which may cause kidney problems. It is important for you to drink fluids to help reduce your chance of dehydration. Tell your healthcare provider right away if you have nausea, vomiting, or diarrhea that does not go away.

Gallbladder problems. Gallbladder problems have happened in some people who use Zepbound. Tell your healthcare provider right away if you get symptoms of gallbladder problems, which may include pain in your upper stomach (abdomen), fever, yellowing of skin or eyes (jaundice), or clay-colored stools.

Inflammation of the pancreas (pancreatitis). Stop using Zepbound and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without nausea or vomiting. You may feel the pain from your abdomen to your back.

Serious allergic reactions. Stop using Zepbound and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue or throat, problems breathing or swallowing, severe rash or itching, fainting or feeling dizzy, or very rapid heartbeat.

Low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Zepbound with medicines that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include dizziness or light-headedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety, irritability, mood changes, hunger, weakness or feeling jittery.

Changes in vision in patients with type 2 diabetes. Tell your healthcare provider if you have changes in vision during treatment with Zepbound.

Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). Zepbound may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking Zepbound before you are scheduled to have surgery or other procedures.

Common side effects

The most common side effects of Zepbound include nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching, hair loss, and heartburn. These are not all the possible side effects of Zepbound. Talk to your healthcare provider about any side effect that bothers you or doesn't go away.

Tell your doctor if you have any side effects. You can report side effects at 1-800-FDA-1088 or www.fda.gov/medwatch.

Before using Zepbound

• Your healthcare provider should show you how to use Zepbound before you use it for the first time.
• Talk to your healthcare provider about low blood sugar and how to manage it. Tell your healthcare provider if you are taking medicines to treat diabetes including an insulin or sulfonylurea.
• If you take birth control pills by mouth, talk to your healthcare provider before you use Zepbound. Birth control pills may not work as well while using Zepbound. Your healthcare provider may recommend another type of birth control for 4 weeks after you start Zepbound and for 4 weeks after each increase in your dose of Zepbound.

Review these questions with your healthcare provider:

• Do you have other medical conditions, including problems with your pancreas, or severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems digesting food?
• Do you take diabetes medicines, such as insulin or sulfonylureas?
• Do you have a history of diabetic retinopathy?
• Are you scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation)?
• Do you take any other prescription medicines or over-the-counter drugs, vitamins, or herbal supplements?
• Are you pregnant, plan to become pregnant, breastfeeding, or plan to breastfeed? Zepbound may harm your unborn baby. Tell your healthcare provider if you become pregnant while using Zepbound. Zepbound may pass into your breast milk. You should talk with your healthcare provider about the best way to feed your baby while using Zepbound.
  
  

• Pregnancy Exposure Registry: There will be a pregnancy exposure registry for women who have taken Zepbound during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. Talk to your healthcare provider about how you can take part in this registry, or you may contact Lilly at 1-800-LillyRx (1-800-545-5979).

How to take

• Read the Instructions for Use that come with Zepbound.
• Use Zepbound exactly as your healthcare provider says.
• Use Zepbound with a reduced-calorie diet and increased physical activity.
• Inject Zepbound under the skin (subcutaneously) of your stomach (abdomen), thigh, or have another person inject in the back of the upper arm. Do not inject ZEPBOUND into a muscle (intramuscularly) or vein (intravenously).
• Use Zepbound 1 time each week, at any time of the day.
• Change (rotate) your injection site with each weekly injection. Do not use the same site for each injection.

If you take too much Zepbound, call your healthcare provider, call the Poison Help line at 1-800-222-1222 or go to the nearest hospital emergency room right away.

Zepbound is approved as a 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg injection.

Learn more

Zepbound is a prescription medicine. For more information, call 1-800-LillyRx (1-800-545-5979) or go to www.zepbound.lilly.com.

This summary provides basic information about Zepbound but does not include all information known about this medicine. Read the information that comes with your prescription each time your prescription is filled. This information does not take the place of talking with your healthcare provider. Be sure to talk to your healthcare provider about Zepbound and how to take it. Your healthcare provider is the best person to help you decide if Zepbound is right for you.

ZP CON BS 25FEB2026

Zepbound^®, its delivery device base and KwikPen^® are registered trademarks owned or licensed by Eli Lilly and Company, its subsidiaries, or affiliates.

CMAT-30872 08/2026 © Lilly USA, LLC 2026. All rights reserved.

From updating health forms to stocking up on medicine cabinet essentials, early preparation is key to keeping the household running smoothly. Samantha Picking, PharmD, senior director of immunizations at Walgreens, breaks down the health to-dos to knock out before the school year starts:

1. Get ahead of seasonal and routine vaccines

The start of a new school year is a good time to ensure the whole family is up to date on routine and seasonal vaccinations, such as those protecting against flu, COVID-19, tetanus, diphtheria and whooping cough.

Pro tip: "Keep in mind that many vaccines take about two weeks to provide protection," Picking said. "That's why it's worth scheduling appointments before kids and teens are back in close contact with classmates and respiratory virus season ramps up."

At Walgreens, patients can schedule vaccination appointments for up to four people in a single visit and book well in advance, giving families more flexibility to plan ahead and save time. myWalgreens^® members can also earn $15 in Walgreens Cash rewards when they spend $5+ on their next eligible in-store purchase, plus 10% back in Walgreens Cash on eligible in-store purchases for 30 days when they get vaccinated.*

2. Coordinate school medications and medical forms

For students with conditions like asthma or severe allergies, early coordination with school staff is essential. Make sure to check the expiration dates on emergency inhalers or epinephrine auto-injectors and verify that the school has updated health forms on file.

Pro tip: "Don't wait until the first day of school to get those required medical forms filled out," Picking said. "Local pharmacy teams can also help refill essential emergency medications, so families are prepared before the first bell rings."

3. Restock the medicine cabinet

Having sick-day supplies on hand is a key part of back-to-school readiness. Take stock of overall household health and wellness needs, including items like daily vitamins, cough drops, antacids, cough medicine, combination flu & COVID-19 tests and other essentials like a first aid kit.

Pro tip: "As a mom of three, I always do a quick check of the medicine cabinet and replace anything that's expired or running low before the school year starts," Picking said. "It only takes a few minutes, but it means you're not caught off guard when someone actually gets sick."

For families short on time, Walgreens has options to grab what you need with 1-hour Delivery and 30-minute Pickup.**

4. Reset daily wellness habits

Transitioning from relaxed summer schedules to structured school routines can be physically taxing for kids and parents alike. Establish a consistent sleep schedule, prioritize nutritious meals and reinforce healthy habits, like proper handwashing and using hand sanitizer, to form a strong foundation for the year ahead.

Pro tip: "Getting enough sleep and practicing good hygiene are two of the simplest ways to start the school year on the right foot," Picking said. "It's easy to let healthy routines slip during the summer, so ease back into them a week or two before school starts."

Walgreens: A partner in health and back-to-school prep

Walgreens is a one-stop destination for vaccinations, over-the-counter essentials and last-minute school supplies. Vaccination appointments can be scheduled online, through the Walgreens app or by calling 1-800-WALGREENS. For any questions, expert pharmacists are ready to provide trusted guidance and personalized support.

*Must be a myWalgreens^® member. Offer available for a limited time and valid for 14 days from vaccination date. Must scan coupon at checkout to earn rewards/activate. Coupon offer not valid in AR, NJ or NY. Limit three coupons per person. See coupon for terms and restrictions. Vaccines subject to availability. Walgreens administers applicable vaccinations for children ages three and older. State-, age- and health-related restrictions may apply. Additional terms and exclusions apply. Complete details, including Walgreens Cash rewards expiration dates, at Walgreens.com/offerdetails.

$15 Offer

• Earn rewards on qualifying in-store purchases of $5+. Limit one storewide coupon redeemed per transaction, up to three redemptions per offer period. Maximum $45 Walgreens Cash rewards per member.

10% Offer

• Earn rewards on qualifying in-store purchases of $1+. Scan once to activate offer. Limit one offer per myWalgreens^® member. Maximum $100 Walgreens Cash rewards. Offer valid for 30 days following activation.

**Delivery in as little as 1 hour and Pickup in as little as 30 minutes based on national averages, actual times may vary. Pickup is available for eligible items when your order is $10 or more (after promo codes and paperless coupons are applied and before taxes). Exclusions, restrictions, and fees may apply. For details, visit Walgreens.com/same-day-delivery and Walgreens.com/Pickup.

A cruise across the Mediterranean took an unexpected turn when Gretchen suddenly became severely ill, experiencing decreased appetite and dehydration. She thought she might have a minor travel-related sickness or infection and visited the ship's physician for care. After running a battery of tests, the doctor delivered a surprising diagnosis. Gretchen had Type 1 diabetes (T1D) and, at that moment, was experiencing diabetic ketoacidosis (DKA), a life-threatening condition that occurs in people with diabetes when ketone levels are too high. For people living with diabetes, their ketones reach dangerously high levels when their body is not able to use glucose as fuel due to a lack of insulin, so instead, the body breaks down fat too quickly, which in turn produces ketones in the blood stream.¹ A DKA event, like the one Gretchen experienced, is how many people find out they have T1D, which accounts for about 20% to 40% of DKA cases.¹

Ambiguous DKA symptoms can delay treatment

For people with diabetes who use insulin, elevated or high ketone levels can lead to DKA, a serious health condition that is on the rise.¹ A study showed that between 2017 and 2024, DKA prevalence among people with Type 1 diabetes increased approximately 24%,² rising from 50 to 62 cases per 1,000 individuals.² DKA is particularly dangerous because in severe cases it can lead to a coma or death.¹ Unfortunately, many patients don't detect it early enough, mistaking their symptoms for other, more common illnesses like the flu, dehydration or food poisoning.^4,5,6

According to Eden Miller, DO, a family practitioner and diabetologist, there are clear reasons behind this alarming trend. "Part of the problem lies in how difficult it can be to distinguish DKA symptoms from less serious, run-of-the-mill medical conditions," said Dr. Miller. "The other part is the underutilization of ketone monitoring methods. While glucose monitoring has advanced, ketones and glucose do not always rise together, and current monitoring tools don't provide continuous visibility into rising ketones. Together, these issues can delay critical treatment."

This trend highlights a clear gap for people living with diabetes. Instead of patients feeling equipped with the insights they need to be proactive and prepared, they are left in a reactive state.

"Improving awareness of DKA and helping people understand what to do when ketones are rising are important opportunities to help reduce DKA risk," said Miller.

Getting treated and gaining confidence

Initially overwhelmed by the diagnosis, once back in the U.S., Gretchen visited an endocrinologist who introduced her to modern diabetes management tools — like Abbott's FreeStyle Libre 3 Plus sensor which continuously measures her glucose levels — and helped guide her through the initial steps of how to live with diabetes. While learning the basics of living with diabetes, Gretchen also learned about ketones, the importance of recognizing DKA symptoms and how to act quickly during a DKA event.

"My diagnosis was a wake-up call, but it wasn't a stop sign. Managing a chronic condition like diabetes doesn't mean shrinking your world; it just means packing a little smarter. By taking control of my health and having a proactive plan, I've reclaimed my love for travel. I want other people to know that living with chronic illnesses shouldn't keep you from making plans, booking trips and living fully."

Tips to keep diabetes management top of mind for travel

Gretchen's experience during her European holiday inspired her to create her own diabetes travel guide to help herself and others living with diabetes proactively plan and diligently monitor their condition, so their vacations stay on track. Below are her top tips for traveling safely and confidently with diabetes.

1. Always stay hydrated: Drink plenty of water, especially when traveling in warm weather and during physical activity like walking through new cities.
2. Pack smart and double up: It's always a good idea to carry extra medications and supplies. This includes insulin, pumps, needles, automated insulin delivery (AID) infusion sets and ketone testing supplies — including blood or urine test strips. Be sure to check the expiration date before packing! Also, bringing a doctor's note can help too in case you get stopped or questioned while traveling with your supplies.
3. Monitor more, adjust often: Travel means changes to your routine. To make sure you stay on top of your diabetes management, check your glucose monitor, pumps and sensors more frequently.
4. Know the signs, act fast: Signs that you may be experiencing a DKA event include extreme thirst, frequent urination, nausea, abdominal pain or fruity-smelling breath. If you experience any of these symptoms, check your glucose and test for ketones immediately.
5. Seek care: When traveling, find the nearest pharmacy or urgent care in case you need medical attention during your trip.

Don't let fear of managing diabetes keep you from seeing the world. Using these tips, you can stay prepared to explore new horizons safely and confidently.

If you or someone you know is living with diabetes, work with a healthcare provider to create a proactive DKA plan so you can feel confident in knowing what to do when ketones are rising or you are not feeling well. For more information about DKA, go to RisingKetones.com.

Sources:

The views expressed in this article should not be used for medical diagnosis or treatment or as a substitute for professional medical advice. Individual symptoms, situations and circumstances may vary.

For U.S. residents - Important Safety Information Product for prescription only, for Important Safety Information please visit FreeStyleLibre.us.

1. Cleveland Clinic. Diabetes-Related Ketoacidosis (DKA). Accessed July 2026 from: https://my.clevelandclinic.org/health/diseases/21945-diabetic-ketoacidosis-dka.
2. SHERR, J., WYSHAM, C., MEHTA, S., & VIRDI, N. (2026). 2977-LB: Trends in the prevalence of Diabetic ketoacidosis and severe hypoglycemia in type 1 diabetes. Diabetes, 75(Supplement_1). https://doi.org/10.2337/db26-2977-lb
3. Umpierrez, G. E. Diabetes Care (2024). https://doi.org/10.2337/dci24-0032
4. Dhatariya, et al. Lancet Diabetes & Endocrinology (2026): https://pubmed.ncbi.nlm.nih.gov/41381175/
5. Virdi, N. Diabetes Technology & Therapeutics (2023). https://doi.org/10.1089/dia.2023.0149
6. Nguyen, K. T. Journal of Diabetes Science and Technology (2022). https://doi.org/10.1177/19322968211042656

What is meningitis?

Meningitis is inflammation of the membranes (called meninges) that surround the brain and spinal cord. Different viruses, bacteria and fungi can cause meningitis, but cases caused by meningococcal disease are especially urgent because they can progress rapidly and may be life-threatening. Of those who develop meningococcal disease, one in 10 will die.

How does meningitis spread?

Meningitis spreads quickly through close contact, including coughing, sneezing, kissing, and sharing drinks, utensils and vapes. Anyone can contract meningococcal disease, but certain groups like preteens, teens and college-age students are at a particularly high risk. At these ages, students spend more time in close contact with their peers in classes, locker rooms, dorms, parties and other group settings.

What are the signs and symptoms?

Meningitis may not seem serious at first. In fact, it can feel like a cold or flu. However, meningococcal disease can become life-threatening within 24-48 hours. Be on the lookout for the following symptoms:

• Fever/flu-like symptoms
• Severe headache
• Stiff neck
• Nausea or vomiting
• Sensitivity to light
• Confusion
• A dark rash (in some cases)

Symptoms can escalate quickly. If your child's symptoms appear suddenly, worsen quickly or feel unusually severe, seek medical attention.

Those who survive the disease may face lifelong complications, including brain damage, hearing loss and limb loss. Recognizing symptoms quickly is important, but preventing meningococcal disease before exposure is the best decision you can make for your teen this fall.

How can I protect my children from meningococcal disease?

Vaccination is the best way to reduce your teen's risk of meningococcal disease. There are two meningitis vaccines that protect against the most serious types (A, B, C, W, Y). Together, these vaccines offer your teen protection against meningococcal disease. These vaccinations are recommended for ages 11-23.

If you're not sure whether your child has received the recommended meningococcal vaccines, talk with your child's doctor. They may be able to help review your child's health records and identify what vaccines may be missing.

Don't wait until school is back in session

This fall, add meningococcal disease prevention to your back-to-school routine. Make sure to check your child's vaccination records. If they haven't received their meningococcal vaccines or need a booster, make sure to schedule an appointment before the first bell rings so you can tackle the new school year with confidence. Or, if they are already back at school, have them get vaccinated at their local clinic. To learn more, visit AmericasMeningitisAlliance.org.

• Wellness routines have become incredibly complicated, and people are seeking effective solutions to support their daily habits without adding more work.
• Ryde: SLEEP simplifies bedtime routines with a quick 2oz shot designed to help you unwind and get ready for better rest.
• The functional shot is designed for busy people who want to feel more prepared for the next day, whether that means work, workouts, travel or everyday commitments.
• Rob Gronkowski brings the message to life by showing that even a "Full Gas" lifestyle needs smart recovery and simple tools that actually fit into real life.
• Alongside SLEEP, Ryde: FOCUS gives consumers another easy functional dietary supplement shot for moments when you want help tuning out distractions and locking in.

Wellness used to be simple. Somewhere along the way, it turned into a cabinet full of supplements and a bedtime routine too complicated to keep up with. As people look to simplify their daily habits without sacrificing results, easy, effective solutions are having a major comeback.

Enter Ryde:, the globally loved well-being brand known for its pocket-size 2oz functional dietary supplement shots. Challenging the increasingly complicated nature of modern wellness routines, Ryde: is proving that taking care of yourself doesn't need to be a tedious chore with its newest launch in partnership with Rob Gronkowski, Ryde: SLEEP: a simple, science-backed solution that fits seamlessly into busy lives.

The power of the night before

Whether preparing for an intense workday, an early morning workout, or back-to-back commitments, feeling your best starts hours before the alarm goes off. Ryde:'s SLEEP shot was built specifically for people who know that the night before matters just as much as the morning after.

Formulated with a delicious blackberry flavor, Melatonin, GABA, L-Theanine and Chamomile, SLEEP is designed to support sleep quality and helps you fall asleep faster.

Informed Choice certified and developed with science-backed ingredients, zero calories, zero sugar and no unnecessary extras, Ryde: delivers functional support without the fuss. Every shot also features Ryde: Ryplenish™, a scientifically backed formula that works right when you need it, making it the perfect daily ally for well-being on-the-go.

"The truth is, in many rural communities, it's often easier and faster to have a pizza delivered than it is to access the healthcare people depend on," said Darren Sabo, CEO of Primefocus Health, the first venture spinout from LG NOVA, LG Electronics' North America Innovation Center.

For the 1 in 5 Americans living in rural areas, this is the reality. If you're managing a chronic illness, the nearest specialist could be a two-hour drive away. If you don't have reliable transportation, or can't take a full day off work, you wait — and hope nothing gets worse.

A whopping 80% of rural America is medically underserved, leading to poorer health outcomes. Rural residents are more likely than urban residents to die early from causes like heart disease, cancer, unintentional injuries, chronic lower respiratory disease or stroke. While other factors may contribute to this higher health risk, access to healthcare remains one of the biggest challenges.

Rural hospitals and health systems continue to face workforce shortages, hospital closures, financial pressures and infrastructure limitations that worsen the situation.

What it's really like on the ground

For rural healthcare teams in 2026, the challenge isn't awareness — it's capacity. Nurses and care coordinators often manage caseloads that would be difficult anywhere, with limited resources and backup support far away. Adding new programs or technology tools to an already stretched team, without redesigning how that care gets delivered, tends to make things harder rather than easier.

For patients, the barriers are immediate. Long distances, unreliable transportation and limited primary care providers and specialists as well as limited broadband/internet access aren't merely inconveniences — they're why people delay care, skip follow-ups and end up in emergency rooms for conditions that could have been managed earlier.

"In parts of Appalachia, patients sometimes travel hours for appointments that take just minutes," added Sabo. "The math doesn't work, and most of the systems built to help them haven't seriously reckoned with that."

The pandemic introduced digital tools including telehealth, which has seen success in increased appointment completion in some rural areas. However, challenges to adopting new technology persist, including patient education and broadband access. West Virginia, for example, ranks 50th nationally in broadband access. And technology isn't the complete answer: Personal relationships with healthcare providers remain crucial.

Finding solutions that put patient needs first

A rural healthcare transformation requires technology and a nourishing human connection. Digital health innovations are one piece of the puzzle, but technology alone won't solve healthcare access challenges in underserved communities.

Solutions need to be designed for the people who need them. Programs producing real results share something in common: They start by asking what patients will actually use and care teams can sustain and build from there.

Primefocus Health is one such solution, reimagining how healthcare happens beyond the clinic by empowering providers and patients through a trusted and customizable digital health platform that bridges the gap between hospital and home. Primefocus Health is building a connected ecosystem where patients can access care, education and remote monitoring tools from home, and providers gain insights they need to guide recovery and improve health outcomes before they become an issue, instead of after.

Technology as a tool, not a substitute for human care

For rural healthcare organizations already operating with limited staffing and growing patient demand, technology adoption — from telehealth appointments and remote patient monitoring (RPM) to AI-powered medical scribes and more — only works when solutions fit naturally into clinical workflows and help providers work more efficiently.

AI and RPM tools must help care teams:

• identify high-risk patients faster
• streamline decision-making
• expand care capacity
• improve outcomes without increasing operational strain

"We're not trying to replace the current healthcare infrastructure and healthcare workers," said Sabo. "We're trying to enhance their abilities."

This operational-first approach is increasingly important as rural hospitals seek scalable healthcare innovation strategies that really work, despite resource limitations.

One model for a connected care program

In rural Appalachia, a connected care program from Primefocus Health in partnership with the Marshall Health Network is serving patients across West Virginia, southern Ohio and eastern Kentucky to put that idea to the test. Its goal is simple: make it easier for patients managing chronic conditions to stay connected with their care team without making travel the price of admission.

The results were tangible:

• Patients stayed engaged.
• Chronic conditions were better managed.
• People who had been driving hours for routine follow-ups were receiving consistent support closer to home.

What made it work wasn't the technology alone. It worked because the program was designed with the health system from the start, built around what care teams could realistically sustain, and held to the standard of whether patients were actually doing better.

"Technologies like AI and RPM have enormous potential, but only when implemented thoughtfully, responsibly and with clinical realities in mind," said Sabo. "The question worth asking is a simple one: Is it actually designed for the people who need it most?"

Rural healthcare is being reimagined right now — in policy, in funding and in technology being deployed across communities that have been underserved for decades.

Learn how Primefocus Health is supporting rural healthcare transformation at PrimefocusHealth.com.

Here are some tips to help your new cat get along more smoothly with cats you already have in your home.

1. Choose your new cat with care

First ensure your new cat is healthy, up-to-date on vaccinations and already spayed or neutered. Reputable animal shelters will be able to provide documentation on each cat's vaccinations and health screenings. Then you may also want to take them to your regular vet for a checkup.

Contrary to popular opinion, it may be best to consider a mature cat that has a history of living successfully with other felines. Younger cats do not necessarily show deference to an older cat, and some older cats are stressed by a young cat's high level of energy.

2. Prepare to bring the new cat home

Consider housing the new cat in a separate room or floor before making any introductions. That means providing a new set of everything a cat needs to be comfortable: litter box, food and water dishes, a soft place to sleep and enrichment like toys, a cat condo or places to climb and perch. You may want to consider revamping spaces throughout your home to provide multiple places cats can enjoy before introducing them.

Make sure your new cat and existing cats won't accidently run into each other every time you open the door to the new cat's space by setting up a baby gate or barrier. In addition, keep your cats' claws clipped so they'll be less likely to do serious injury if they get into a scrap when they first meet.

3. Be patient

Give your new feline lots of time to get used to you, and the space, before attempting introductions. Every cat is an individual, and may take time to become comfortable in their new home. Because they're so unique, you won't know who'll be more stressed about the introduction — your existing cat(s) or the newcomer.

Chances are good your cats are aware of each other long before they can see one another. Feeding or offering treats on opposite sides of the door can foster positive associations before they meet.

4. Introduce them, one sense at a time

Depending on your home's layout, your cats may already smell and/or hear each other. At the beginning, find ways to limit the senses by which they're encountering each other. For example, let them smell each other's scent by swapping their beds or blankets for a few days. If your home allows, try a room swap, letting each cat inhabit the other's space for a while. You can also try feeding them on opposite sides of a baby gate with a sheet draped over it, so they'll hear and smell each other without visual contact.

Later, if you have a glass or plastic door or partition, you could feed them within eyesight but without them being able to smell or hear each other well.

5. Watch their behavior

You probably recognize signs of displeasure in your cat, like hissing, growling or their fur fluffing up. More subtle signs of stress can be ears flattening, tail twitching or the death stare: unbroken eye contact between cats who appear frozen in place.

Positive body language may also be visible: tail straight up, ears facing forward. One cat may lean forward to sniff the other cat, even showing playfulness by rolling on their back to reveal their tummy. Signs like this show they're ready to accept the other cat — though it may not be mutual yet.

If you see signs your cats aren't happy, don't panic. A little hissing or growling doesn't mean they'll never be friends. Try giving them treats together, or coaxing them to play with favorite toys at the same time. Most importantly, keep their interactions limited and supervised while they figure out this new relationship.

Depending on your individual cats, it may take weeks, months or even years before they happily coexist, but that doesn't mean all-out warfare. With patience and preparation, you can help your cats successfully navigate their new social interactions.

Dr. Hakan Kaya is a board certified community-based hematologic oncologist and has been compensated by GSK for participating in this article.

Most people with multiple myeloma get treatment close to home. They do not usually go to larger major academic centers, but instead many receive care at their local community oncology clinics.¹ These local clinics help patients stay near their families, support systems and daily routines during treatment. They also coordinate the many steps involved in starting and continuing care, including helping with insurance approvals and billing logistics. When those steps work together smoothly, patients can start treatment without unnecessary delays or added stress.

"Approximately 70% of patients with multiple myeloma are treated in community settings," said Dr. Hakan Kaya, a Hematologic Oncologist at Cancer Care Northwest. "That means even small improvements in how care is delivered at the community level can make a meaningful difference for patients."

Multiple myeloma is a blood cancer that starts in the bone marrow, where abnormal plasma cells grow and crowd out healthy blood cells.² As the second most common blood cancer in the U.S., roughly 36,000 new patients will be diagnosed this year.^3,4 Despite meaningful advancements in treatment, the disease often returns or becomes resistant. Many patients will go through several lines of therapy, making timely access and prompt initiation of the next therapy especially important.⁵

A new update may help this process. The Centers for Medicare & Medicaid Services (CMS) recently assigned BLENREP (belantamab mafodotin-blmf) for injection 70 mg, a permanent billing code, known as a J-Code (J9053). This standardizes how the therapy is billed and reimbursed.

While it may sound technical, this can really matter for multiple myeloma patients who may be experiencing cycles of remission and relapse. When treatment decisions need to happen quickly, a clearer reimbursement process can help patients promptly start the next step in their care.

BLENREP is a prescription medicine approved by the U.S. Food and Drug Administration for use in combination with the medicines bortezomib and dexamethasone to treat adults with multiple myeloma who have received at least 2 prior treatments, including a proteasome inhibitor and an immunomodulatory agent, and whose cancer has come back or did not respond to prior treatment. It is not known if BLENREP is safe and effective in children.

It is also one of the available treatment options for multiple myeloma that is designed to be administered across a range of healthcare settings, including community clinics.

BLENREP can cause serious side effects, including eye problems. These eye problems are common and can sometimes be severe, leading to vision changes or even vision loss. Changes can occur on the surface of the eye (cornea) and may cause symptoms such as: Blurred or decreased vision, dry eyes, sensitivity to light, eye irritation or pain, or feeling like something is in your eyes. Ulcers on the surface of the eye (corneal ulcers), including with infection, may also happen during treatment with BLENREP. These are not all of the possible side effects of BLENREP.

Eye exams are required before starting treatment, before each dose, and as needed if new or worsening eye problems occur. It's important that you keep all of your eye care appointments because some changes can happen without symptoms and may only be seen on an eye exam. Use preservative-free artificial tears at least four times per day during treatment and avoid contact lenses unless directed by your eye specialist. Use caution when driving or operating machinery because BLENREP may cause changes to your vision.

Because of the risk of eye problems, BLENREP is available only through a restricted program called the BLENREP Risk Evaluation and Mitigation Strategy (REMS). Your healthcare provider will give you the BLENREP REMS Patient Guide, which describes the risk of eye problems, and will explain the REMS program to you. To receive BLENREP, you must enroll in the REMS program and receive eye exams during treatment.

Please see Important Safety Information below and the full Prescribing Information, including Boxed Warning and Medication Guide, for more details.

"There is a lot of paperwork behind the scenes when it comes to cancer care," added Dr. Kaya. "Even small gaps in reimbursement clarity can create delays at the critical moment a patient should be starting their next treatment."

This is especially important for patients with relapsed or refractory multiple myeloma, where treatment decisions must build on what has or hasn't worked before, alongside individual patient needs.

"In later lines of therapy, treatment decisions aren't just about clinical factors," said Dr. Kaya. "Access, travel, and setting of care all play a role in determining the best path forward."

Those living with or caring for someone with multiple myeloma are encouraged to talk with their care teams about what treatment is best for them, including what side effects or logistical factors may come into play.

To learn more about this treatment option, visit BLENREP.com.

APPROVED USE

BLENREP is a prescription medicine used in combination with the medicines bortezomib and dexamethasone to treat adults with multiple myeloma who have received at least 2 prior treatments, including a proteasome inhibitor and an immunomodulatory agent, and their cancer has come back or did not respond to prior treatment.

It is not known if BLENREP is safe and effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about BLENREP?

BLENREP can cause serious side effects, including:

• Eye problems. Eye problems are common with BLENREP and can also be severe. BLENREP can cause changes to the surface of your eye, which can lead to symptoms of eye problems, including:
  • decreased vision
  • blurred vision
  • dry eyes
  • sensitivity to light
  • feeling like something is in your eyes
  • eye irritation
  • eye pain

Ulcers on the surface of the eye (corneal ulcers), including with infection, may also happen during treatment with BLENREP.

Tell your healthcare provider right away if you notice any new or worsening eye symptoms or vision changes during treatment with BLENREP.

Your healthcare provider will refer you to an eye care specialist (such as an ophthalmologist or optometrist) to check your eyes before you start treatment, before you receive each dose of BLENREP, and as needed for any new or worsening eye problems. It is important that you:

• • Keep all of your eye care appointments because some changes can happen without symptoms and may only be seen on an eye exam
  • Use preservative-free artificial tears at least 4 times per day starting with your first infusion and continuing until the end of treatment with BLENREP
  • Avoid wearing contact lenses during treatment with BLENREP unless directed by your eye care specialist
  • Use caution when driving or operating machinery because BLENREP may cause changes to your vision

Because of the risk of eye problems, BLENREP is available only through a restricted program called the BLENREP Risk Evaluation and Mitigation Strategy (REMS). Your healthcare provider will give you the BLENREP REMS Patient Guide, which describes the risk of eye problems, and will explain the REMS program to you. To receive BLENREP, you must enroll in the REMS program and receive eye exams during treatment. See "What are the possible side effects of BLENREP?" for more information about side effects.

What are the possible side effects of BLENREP?

BLENREP can cause serious side effects, including:

• See "Eye Problems" in "What is the most important information I should know about BLENREP?"
• Decrease in platelets (thrombocytopenia) is common with BLENREP and can also be severe. Platelets are a type of blood cell that help your blood to clot. Your healthcare provider will check your blood cell counts before you start treatment with BLENREP and during treatment as needed. Tell your healthcare provider if you get any bleeding or bruising during treatment with BLENREP

The most common side effects of BLENREP when given with bortezomib and dexamethasone include:

• See "Eye problems" in "What is the most important information I should know about BLENREP?"
• upper respiratory tract infection
• liver problems
• diarrhea
• tiredness
• pneumonia
• cataract
• COVID-19

The most common severe abnormal blood test results during treatment with BLENREP include decreases in platelets, white blood cells, and hemoglobin, and increases in certain liver enzymes.

Tell your healthcare provider right away if you get new or worsening unexplained signs or symptoms of lung problems, including shortness of breath, chest pain, or cough.

Your healthcare provider may decrease your dose, temporarily stop, or completely stop treatment with BLENREP if you get serious side effects.

BLENREP may affect fertility in males and females, which may affect your ability to have children. Talk to your healthcare provider if this is a concern for you.

These are not all of the possible side effects of BLENREP.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before receiving BLENREP, tell your healthcare provider about all of your medical conditions, including if you:

• have or had vision or eye problems
• have or had bleeding problems
• are pregnant or plan to become pregnant. BLENREP can harm your unborn baby
  Females who are able to become pregnant:
  • Your healthcare provider will do a pregnancy test before you start treatment with BLENREP
  • Use effective birth control during treatment with BLENREP and for 4 months after the last dose. Talk to your healthcare provider about birth control methods you can use during this time
  • Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with BLENREP
• Males with female partners who are able to become pregnant:
  • Use effective birth control during treatment with BLENREP and for 6 months after the last dose
• are breastfeeding or plan to breastfeed. It is not known if BLENREP passes into your breast milk. Do not breastfeed during treatment with BLENREP and for 3 months after the last dose

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088. You may also report negative side effects to GSK at gsk.public.reportum.com or 1-888-825-5249.

Please see full Prescribing Information, including Boxed Warning and Medication Guide for patients.

Intended for US audiences.

Trademarks are owned by or licensed to the GSK group of companies.

©2026 GSK or licensor.

PMUS-BLMCOCO260004 July 2026

Produced in USA.

But for many children, the real adjustment happens in the weeks after school begins.

New teachers, academic expectations, social dynamics, extracurricular activities and changing routines can create stress that isn't always obvious. While some children openly talk about their worries, others show signs through changes in behavior, sleep, mood or motivation.

"Many families focus on getting through the first day of school, but the real adjustment often happens over the following weeks," said Dr. Sascha Arbouet, child/adolescent psychiatrist and Medical Director, Pediatrics at Bend Health, a national provider of pediatric mental health care. "Children aren't just adjusting to being back in the classroom. They're taking on new teachers, new routines, new classmates, new expectations and often a full schedule of extracurricular activities. That's a lot for any child to process. While the start of the school year is often exciting, it can also be mentally and emotionally exhausting. Paying attention to changes in mood, sleep, behavior or school avoidance can help families identify concerns early."

Parents and caregivers can play an important role in helping children navigate the transition and build confidence as the school year gets underway.

1. Ask intentional questions

Many children struggle to answer broad questions like, "How was school today?"

Instead, try asking more specific questions:

• What was the best part of your day?
• What felt challenging?
• Who did you spend time with today?
• Is there anything you're worried about this week?

Small, consistent conversations can help children feel comfortable sharing concerns before they become bigger issues.

2. Watch for changes in behavior

School-related stress doesn't always sound like, "I'm scared."

Children may become more irritable, withdrawn, emotional, tired or resistant to school routines. Others may seem less interested in activities they typically enjoy.

Some sadness that summer is over, irritability from feeling exhausted or anxiety about a new routine is completely normal during the first few weeks of school. What becomes more concerning is when those reactions are persistent or begin interfering with everyday life. If a child doesn't want to go to school several days each week, consistently struggles to sleep or eat, or their mood or behavior continues to worsen instead of improving, it may be time to seek additional support.

3. Prioritize sleep and routines

One of the simplest ways to support children's mental health is maintaining consistent routines.

Regular sleep schedules, predictable mornings and structured after-school routines help children feel more secure during periods of change. Sleep plays an important role in emotional regulation, attention, learning and overall well-being.

Caregivers should also be mindful of overscheduling. Sports, clubs and extracurricular activities can be valuable, but children also need time to recharge.

4. Stay connected with teachers and other trusted adults

Families don't have to navigate school transitions alone.

Teachers, school counselors, coaches and other trusted adults can often provide valuable insight into how a child is adjusting. Open communication between home and school can help identify concerns early and create a stronger support system around the child.

This can be especially helpful for children with ADHD, anxiety, autism, learning differences or other behavioral health needs.

5. Know when to seek help

Some adjustment challenges improve naturally as children settle into new routines. Others may persist or worsen over time.

Parents and caregivers should consider seeking professional support if anxiety, mood changes, behavioral challenges, school avoidance or emotional distress begin interfering with daily life, friendships, family relationships, sleep or academic performance.

"The earlier we identify concerns, the easier it is to provide support before small challenges become bigger obstacles," said Arbouet. "Parents and caregivers know their children best. If something feels different or concerning, it's worth paying attention to."

Bend Health provides virtual mental health care, coaching, psychiatry and caregiver support for children, teens and young adults. By working with young people and their families, Bend helps build practical skills that support emotional well-being throughout the school year and beyond.

For more information, visit www.BendHealth.com.

Not long after relocating, Brandon began noticing red, scaly patches forming on his elbows that caused itching and burning sensations.

"The change in weather, plus navigating new challenges with grad school was quite an adjustment," Brandon said. "The cold and dryness seemed to trigger symptoms on my skin, and I couldn't figure out what I could do to manage it."

After searching for answers through his own research and trying a range of over-the-counter products, Brandon spoke with his dermatologist and received a diagnosis of plaque psoriasis. Like many people living with the condition, he went on to try a variety of prescription treatments in search of relief. While some options, such as topical corticosteroids, provided short-term improvement, he struggled to find an approach that supported long-term symptom management.

"I tried so many different treatments, but none of them worked for me," he said. "It was frustrating and, at times, overwhelming."

Plaque Psoriasis at a Glance

Plaque psoriasis is a common, chronic skin disease that affects nearly 9 million people in the United States. While symptoms such as redness, scaling, and flaking are often visible on the skin, itch can be one of the most burdensome symptoms.

Psoriasis can appear as raised, red areas of skin covered with silvery scales. These patches can occur anywhere on the body, including the knees, elbows, torso, scalp, and sensitive areas where skin touches skin, such as the underarms or groin. On darker skin tones, plaques may appear gray, purple, or brown. For many people, symptoms can come and go over time and may worsen due to factors like stress, weather changes, illness, skin injuries, alcohol use, or certain medications.

Although symptoms often begin between the ages of 15 and 25, plaque psoriasis can develop at any age, even in early childhood, and persist for decades.

"Whenever I would leave the house, I was worried people would see my plaques and think they were contagious. I knew plaque psoriasis is a chronic condition, so I would likely be living with these symptoms for years to come, but there didn't seem to be a treatment that could effectively manage them for me," continued Brandon. "I didn't see many people with plaque psoriasis talking openly about their experience, so I consistently found myself wondering, am I the only one going through this? Why me?"

Treatment for Plaque Psoriasis

That's when Brandon researched long-term treatment options and spoke with his dermatologist about ZORYVE^® (roflumilast) cream 0.3%.

"I know that everyone's experience is different, but for me, ZORYVE cream helped clear my plaques and relieve itch," said Brandon. "It's non-greasy and it fit into my daily routine with ease. Seeing my skin look less red, scaly, and irritated over time has given me an option for managing my psoriasis long term."

ZORYVE cream 0.3% is the first once-daily, steroid-free therapy approved for adults and children as young as 2 years of age with plaque psoriasis, including intertriginous psoriasis (psoriasis in areas of skin-to-skin contact such as under the arms, and in the groin). Clinical studies of ZORYVE cream 0.3% demonstrated rapid improvement in clearance of plaques and reduction in symptoms, including itch. The most common side effects included diarrhea, headache, trouble sleeping, nausea, application site pain, upper respiratory tract infection, and urinary tract infection.

"After trying so many other treatment options, I was hopeful that ZORYVE could give me the relief I was looking for, and I like that it can be used continuously to manage my psoriasis for the long term," Brandon said. "Talking with my dermatologist helped me better understand my options and find a treatment plan that fit my needs."

"ZORYVE cream 0.3% can be used once daily, anywhere on the skin, including sensitive areas where psoriasis can be more difficult to manage, and there are no limitations on duration of use," said Lisa Swanson, MD, FAAD, a board-certified dermatologist and pediatric dermatologist. "ZORYVE is non-greasy and has moisturizing properties and was made without sensitizers or irritants. My patients like that ZORYVE is steroid-free and easy to incorporate into their daily routine. Having treatment options that my patients can use consistently over time can be an important part of managing a chronic condition like plaque psoriasis."

In two clinical trials of 881 individuals living with plaque psoriasis, 40% of 576 individuals achieved clearer skin after using ZORYVE for 8 weeks compared to 7% of 305 who used a cream without the active ingredient. 69% of 447 individuals treated with ZORYVE also experienced itch relief, compared to 31% of 231 who used a cream without the active ingredient.

Approved Use

ZORYVE cream 0.3% is a prescription medicine used on the skin (topical), including in areas with skin folds, to treat plaque psoriasis in adults and children 2 years of age and older.

It is not known if ZORYVE cream 0.3% is safe and effective in children with plaque psoriasis younger than 2 years of age.

IMPORTANT SAFETY INFORMATION

ZORYVE is for use on the skin (topical use) only. Do not use ZORYVE in your eyes, mouth, or vagina. Do not use ZORYVE if you have certain liver problems.

Before using ZORYVE, tell your healthcare provider about all of your medical conditions, including if you:

• have liver problems.
• are pregnant or plan to become pregnant. It is not known if ZORYVE will harm your unborn baby.
• are breastfeeding or plan to breastfeed. It is not known if ZORYVE passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with ZORYVE. Breastfeeding women using ZORYVE should use it on the smallest area of the skin and for the shortest time needed. Do not apply ZORYVE directly to the nipple or areola to avoid contact with your baby.

Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

The most common side effects of ZORYVE cream 0.3% include:

• diarrhea
• headache
• trouble sleeping
• nausea
• application site pain
• upper respiratory tract infections
• urinary tract infections (UTIs)

These are not all of the possible side effects of ZORYVE. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Patient Information for ZORYVE.

Talk to your healthcare provider and learn more at ZORYVE.com, or visit ZORYVE.com/book-virtual-appointment to be connected to an independent board-certified dermatologist for a virtual appointment.

Photo courtesy of Brandon Shamoun, an actual patient who has been treated with ZORYVE cream and is being compensated for his time contributing to this article.

© 2026 Arcutis Biotherapeutics, Inc. All rights reserved. US-CRP-151-00040 08/26

(BPT) - Key takeaways

• Protein is making headlines right now, while most Americans overlook healthy fats and fiber.
• It's easy to get more of these important nutrients with avocados. The healthy fats and fiber in avocados help keep you fuller longer, help manage blood sugar and may help prevent type 2 diabetes.
• Not just toast and guac: Avocados are great for every meal including breakfast and snacks. Try this summer sensation: Avocado and Blueberry Chia Seed Pudding at LoveOneToday.com/avocados.

Everyone seems to be focused on protein these days. The truth is that most people already get enough protein. But a recent report from the 2025 Dietary Guidelines Advisory Committee found that 95% of Americans fall short of consuming the recommended amounts of fiber to promote health and reduce the risk of chronic disease. At the same time, many also eat too much saturated fat versus unsaturated fat.

Dietary fiber and healthy fats are key players in supporting overall metabolic health.

Scientists keep investigating the health benefits of avocado goodness. Avocados pull double duty by offering fiber and healthy fats in one nutrient-dense package, slowing digestion to help you feel fuller longer, which can offer weight management benefits, may help with type 2 diabetes management and play a role in blood sugar management. Additionally, if you're using a GLP-1, healthy avocados can help small meals feel more filling and satisfying while meeting your nutrient needs.

In fact, according to a study of more than 27,000 adults, supported by the Avocado Nutrition Center and published in the journal "Internal Medicine Review," people who ate just over half of an avocado per day weighed 7.5 pounds less, had smaller waist sizes and tended to have healthier overall eating habits, including higher intakes of fiber and healthy fats, compared to people who didn't eat avocados. While these findings are encouraging, they show an association, not cause and effect, and thus more research is needed to confirm these findings in other populations.

Avocados make it easy

Changing your eating habits to include more fiber and healthy fats can be easy. This summer, you can set and meet daily goals for eating more of these two key nutrients with one whole food — fresh avocado. And there are so many ways to enjoy avocado throughout the day — from breakfast smoothies and chia puddings to satisfying snacks and dips, refreshing frozen treats and even baked goods. Creamy, delicious avocados can make it easy to hit your daily fiber and healthy fats goals.

"There are so many simple avocado recipes to add flavor, variety, nutrition and joy across the day," said Chaparro. "One new favorite for me is Avocado and Blueberry Chia Seed Pudding. One serving of this delicious pudding delivers healthy fats and contains half of the daily recommended amount of fiber. An easy, filling breakfast or snack!"

It's time to think beyond protein

Remember, protein is important, but the nutrition gap experts are prioritizing to fill is with fiber and healthy fats. One food that makes it easier to get both fiber and healthy fats in each bite is avocados. They're a delicious addition to breakfasts, snacks and everyday meals. To discover more ways to incorporate avocados in your diet with easy recipes, head to LoveOneToday.com/avocados.

How you can help fight fraud

One of the most powerful weapons against Medicare fraud is you, an informed person with Medicare who knows how to spot a scam.

Fraudsters are constantly looking for ways to steal Medicare numbers and use them to submit false claims for services that were never provided or never needed.

Your Medicare number is valuable to criminals. If scammers gain access to it, they can bill Medicare in your name and leave false information in your medical records. That misinformation could interfere with your ability to receive the care you need.

When you spot fraud — report it right away by calling 1-800-MEDICARE.

The scams are getting bolder

Scammers are becoming increasingly sophisticated. They use phone calls, text messages, emails, social media and even door-to-door visits to target older Americans.

One of the fastest-growing scams involves hospice and home health fraud. Scammers pose as salespeople and offer seemingly "free" services such as cooking, cleaning, medical equipment, transportation or nutritional products in exchange for your signature. Their goal is to get people with Medicare to sign paperwork that enrolls them in hospice or home health services they don't need. This allows scammers to bill Medicare while taking away access to care you may need in the future.

Other common scams include:

• Fake genetic testing schemes – Offers for "free" DNA testing at health fairs, community events or over the phone in exchange for your Medicare number.
• Durable medical equipment fraud – Billing Medicare for wheelchairs, knee braces, back braces or other equipment you never received or never needed.

The rule is simple: If someone offers you something for "free" in exchange for your Medicare number, it's a scam. Hang up. Delete the message. Walk away. And report it.

Protect. Detect. Report.

You can help stop Medicare fraud by following three simple steps:

PROTECT your Medicare card like you would your Social Security number. Only share your Medicare number with trusted health care providers, hospitals or pharmacies. Medicare will never call you unexpectedly asking for your Medicare number.

DETECT fraud by reviewing your Medicare claims statements. Make sure every service listed is one you received. Watch for red flags such as duplicate charges or services you don't recognize.

REPORT suspicious activity immediately by calling 1-800-MEDICARE (1-800-633-4227) or visiting Medicare.gov/Fraud. Reporting concerns quickly helps Medicare identify patterns and stop scammers before they can target others.

Help keep Medicare strong — let's protect it together

Medicare fraud costs taxpayers billions of dollars every year, but the damage goes beyond financial losses. Fraud can compromise medical records, undermine trust in the health care system and harm beneficiaries who depend on Medicare every day.

By staying alert, safeguarding your Medicare information and reporting suspicious activity, you can help stop fraud before it starts.

Get wise. Together, we can crush Medicare fraud.

To learn more, visit www.medicare.gov/fraud. To report potential fraud, call 1-800-MEDICARE (1-800-633-4227).

By learning more about the genetic makeup of a person's tumor, researchers can begin to see those differences more clearly and use them to guide future scientific and clinical advances.

A Novel Approach

Merck and Moderna are working together to explore an innovative approach to cancer care — one that seeks to address each individual's cancer with a "one medicine for one patient" mindset. This research centers on an individualized neoantigen therapy (INT) approach, which is designed with the intent to train and activate a patient's immune system to specifically identify and then destroy cancer cells.

Every person's tumor has a distinct "fingerprint" made up of mutated genes resulting in abnormal proteins, called neoantigens. An INT, leveraging mRNA as the body's instruction-carrying molecule, could help train a patient's immune cells to recognize these cancer "fingerprints" as foreign and potentially launch an immune response against those cancer cells to help their own body fight back.

"Because the genetic makeup of a patient's cancer is unique to that person, we believe there is a need for innovative therapies that can be tailored to a patient's tumor with the potential to enhance immune surveillance for each person's specific cancer," said Dr. Vassiliki Karantza, Associate Vice President, Global Clinical Development, Merck Research Laboratories.

Using these insights, researchers identify genetic mutations of a patient's cancer by performing an analysis of their blood and tumor samples to select which neoantigens may be best suited to activate the patient's immune cells. An INT is then created with the intent to specifically treat the individual patient's cancer.

"Our teams are working relentlessly to explore this new approach, which is grounded in the fact that every patient's cancer has unique features," said Dr. Michelle Brown, Head of Oncology Portfolio Development at Moderna. "Made possible by mRNA technology, this approach could represent a shift toward more personalized care in cancer, where we design therapies based on each patient's specific biology — moving us toward creating one medicine for one patient."

Research Underway

Researchers are currently conducting studies to better understand how INTs may help train the body's immune system. There are currently no U.S. FDA-approved individualized neoantigen therapies.

For more information about ongoing research in cancer, visit: Merck.com or Moderna.com.

This information is provided by Merck and Moderna.

Copyright © 2026 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved.

To support families as they prepare, Registered Dietitian and Nutritionist Dawn Jackson Blatner offers these helpful tips for reducing stress and boosting energy every day.

Ease into a new schedule

After a summer full of inconsistent schedules, it can be a challenge for kids and parents alike to adapt to the more rigorous school year routine. To make this transition a lot smoother, begin adapting to a back-to-school schedule about two weeks before classes start. By gradually shifting bedtime and wake-up times 15 minutes earlier every few days, everyone will find it a lot easier to wake up energized every morning.

Power down before bed

Building healthy bedtime habits can make it easier to get the quality sleep your body needs. To help wind down at the end of the day, Blatner recommends limiting screen time about 60 minutes before bed.

"Reducing exposure to phones, tablets and other electronic devices in the evening can help promote more restful sleep, which makes it easier to wake up feeling refreshed and ready to tackle the day ahead."

Wake up the body and mind

A consistent morning routine can help reduce stress and set a positive tone before the school day begins. Blatner recommends incorporating 5 to 10 minutes of dynamic stretching, such as arm circles, leg swings, shoulder rolls or walking lunges to help wake up both the body and mind.

These dynamic movements help increase blood flow, loosen muscles after sleep and improve alertness, helping you start the day feeling energized and prepared for whatever's ahead.

Start your day with a balanced breakfast

Beginning each morning with a balanced breakfast is one of the best ways to fuel focus, support steady energy and prepare both kids and parents for a busy day ahead. Blatner recommends combining high-quality protein with colorful vegetables to help support overall wellness throughout the school and workdays.

One easy way to put that advice into action is by making these Broccoli & Cheddar Egg Muffins from Eggland's Best. Made with protein-rich eggs, broccoli, cheddar cheese and red bell pepper, they're a nourishing grab-and-go breakfast that makes busy school mornings a little easier.

Eggland's Best eggs contain more than double the Vitamin B12 compared to ordinary eggs to help support energy between breakfast and lunchtime. Eggland's Best eggs also contain six times more Vitamin D to support your cognitive wellness and motor function. Plus, Eggland's Best eggs have 25% less saturated fat, more than double the Omega-3s and ten times more Vitamin E compared to ordinary eggs.

Broccoli & Cheddar Egg Muffins

Prep time: 10 minutes; Cook time: 18-20 minutes; Yield: 12.

Ingredients

• 8 Eggland's Best eggs, large
• 1/4 cup milk at room temperature
• 1 cup broccoli florets
• 1/2 cup shredded cheddar cheese
• 1/4 cup diced red bell pepper
• 2 tablespoons chopped fresh chives, for garnish

Preparation

1. Preheat Oven to 350°F. Grease a 12-cup muffin tin or line with paper liners.
2. Whisk together eggs, milk, salt, and pepper until smooth.
3. Mix in chopped broccoli, shredded cheddar cheese, and diced red bell pepper into the egg mixture.
4. Pour the egg mixture into the muffin cups about 3/4 full.
5. Place the muffin tin in a larger baking dish. Carefully pour hot water into the larger dish, filling it about halfway up the sides of the muffin tin.
6. Bake for 18-20 minutes until the egg cups are set.
7. Allow the egg cups to cool in the tin for 5 minutes. Transfer to a wire rack, then garnish with chopped fresh chives before serving.

Pro tips: Bake these muffins the night before and store them in an airtight container for an easy breakfast that saves time on hectic weekday mornings.

Find this and more recipe inspiration at Egglandsbest.com/recipes.

"Positive daily habits and good nutrition can make a big difference to support overall health and well-being, especially at times of transition that can be stressful for both kids and adults," added Blatner.

By following these tips, you and your family will feel ready to start the school year with more pep in your step.

Types of blood cancer: leukemia, lymphoma and myeloma

The most common types of blood cancer are leukemia, lymphoma and myeloma. Together, they account for the majority of hematologic malignancies, with more than 190,000 new cases projected each year in the U.S.

• Leukemia forms in the blood and bone marrow and is caused by the rapid production of abnormal white blood cells. There are several types of leukemia, which include acute lymphoblastic leukemia, acute myeloid leukemia, chronic lymphocytic leukemia and chronic myeloid leukemia.
• Lymphoma develops in the lymphatic system, a network of organs, vessels and tissues that helps protect the body from infection. It is often classified as either Hodgkin lymphoma or non-Hodgkin lymphoma, depending on the type of lymphocyte involved and specific cellular features.
• Myeloma, also known as multiple myeloma, forms in plasma cells found in the bone marrow. Unlike cancers that first appear in one location, myeloma can occur in multiple areas of the bone marrow at the same time.

Rare blood cancers: myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDS)

In addition to the previously listed more common blood cancers, there are rarer related blood disorders, such as myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDS). About 20,000 new cases of MPNs and MDS are diagnosed each year in the U.S. MPNs occur when the bone marrow produces too many blood cells, while MDS develops when blood cells do not mature properly and are unable to become healthy cells. The main types of MPNs include essential thrombocythemia, primary myelofibrosis and polycythemia vera.

As the number of people affected by blood cancers and disorders continues to rise, scientists at Merck are exploring innovative strategies aimed at improving outcomes for patients living with these complex and challenging conditions. These approaches focus on enhancing the body's response to cancer, targeting cancer cells more precisely and addressing pathways that drive cancer growth.

Merck is currently investigating several potential innovative treatment approaches for hematologic malignancies across a broad range of different disease pathways, including:

• Targeting ROR1, a protein that is overexpressed in multiple hematologic malignancies

• Evaluating the role of Bruton's tyrosine kinase, including common mechanisms of resistance for patients with certain hematologic malignancies

• Targeting lysine-specific demethylase 1 (LSD1), an enzyme that is potentially important for regulating the uncontrolled reproduction of blood stem cells and the maturation of blood cells in the bone marrow

• Evaluating the role of the BCR::ABL novel protein in white blood cell proliferation

• Researching T-cell engagement for certain types of leukemia and lymphoma

"Our team is building on our legacy in oncology to understand how various mechanisms and modalities could address blood cancers in innovative ways," said Dr. Shweta Jain, vice president, oncology clinical research, Merck Research Laboratories. "By exploring multiple potential novel mechanisms of action across a broad range of blood cancers and disorders, we hope to help address longstanding unmet needs for patients with hematologic malignancies."

Through ongoing studies and clinical trials, Merck is working to advance clinical research for patients living with blood cancers and disorders. Learn more about Merck's hematology research and clinical trials.

In the U.S. alone, three in four adults have at least one chronic disease, according to the Centers for Disease Control and Prevention (CDC). As these numbers continue to rise, it's more important than ever that people take steps to reduce their risk of developing chronic diseases.

That said, if you've ever felt overwhelmed by conflicting advice about nutrition, exercise or wellness, you're not alone.

Recent research from global healthcare company Abbott, conducted by Kantar, revealed that while 74% of U.S. adults believe most chronic diseases are preventable, only one in four feel very confident in their ability to care for their health.

When you don't know what to do or you feel overwhelmed or confused by sometimes conflicting and changing guidelines, making any change to your health habits can seem impossible. However, experts say taking care of your health can be easier than you think and often comes down to small, consistent choices.

"Healthy living is within reach for most people," said Dr. Dominique R. Williams, MD, MPH, Nutrition Medical Director at Abbott. "Simple, consistent habits around movement, nutrition and preventive care can make a big difference in your overall and long-term health."

Williams offers five simple, practical steps you can take every day to reclaim and support your long-term health.

Keep track of your basics

Want to improve your health but aren't sure where to start? Begin by paying attention to three basics: sleep, hydration and daily movement. You don't need a complicated system. You can use your phone, a notebook or a smartwatch to spot patterns and identify small changes that can make a difference.

Add nutritious foods to every meal

According to Abbott's study, 96% of Americans believe good nutrition helps prevent chronic disease, but only 30% say they personally eat "very healthy." While you may be tempted to overhaul your diet to improve your health, there are easier steps you can take.

Instead of focusing on what to cut from your diet, shift your mindset and add nutrient-dense foods to your meals. Williams recommends incorporating more colorful produce, legumes and nuts into your current meals. It can be as simple as tossing a handful of spinach into your morning eggs, adding beans to your favorite soup or grabbing a handful of almonds for an afternoon snack.

Maintain preventive care

If you haven't already, schedule your annual checkup and any routine screenings that are due. This information gives your care team a clearer picture of your health, and they may be able to catch potential issues like high blood pressure or blood sugar that can lead to chronic disease.

Find ways to move every day

It's no secret that exercise is good for your body. It is recommended that adults get 150 minutes of moderate-intensity physical activity a week. That number may sound daunting, but don't let it intimidate you — you don't have to do it all at once.

"Start small," Williams said. "Breaking daily activity into bite-size pieces is easier to do and maintain than committing to an hour or more at the gym."

This week, try taking a 10-minute walk after lunch or doing a quick 15-minute body weight routine in your living room while you watch your favorite show. Remember, every single step counts and just a little more than 20 minutes a day will get you to the recommended goal. That could simply mean taking the stairs during the day and doing a short walk before or after dinner.

Schedule daily self-care

Chronic stress can take a toll on your health. Get ahead of stress by intentionally scheduling daily self-care. Whether you read a book, spend time in nature, go out for dinner with friends or spend five minutes meditating, these small acts of daily care can go a long way in lowering stress.

Small steps can make a big impact

Every small healthy habit you build can help propel you toward a healthier life and work to prevent chronic disease. To learn more about the survey findings and discover additional practical tips for turning your healthy intentions into daily action, visit Abbott.com/HealthyHabits.

What's getting in the way of a good night's sleep

If falling asleep is challenging, it could be your mind that's robbing you of precious zz's. In a recent Viactiv^® survey* of 2,000 U.S. women, more than 4 in 10 (43%) said that feeling stressed, mentally wound up, or unable to stop thinking is what most often gets in the way of feeling ready for sleep at night. The survey also found that 28% report feeling physically tense and having trouble relaxing their bodies before bed.

Unfortunately, many are unintentionally making it harder for themselves by sabotaging their sleep readiness with bedtime routines that run counter to gold-standard sleep hygiene practices. The survey found that 61.3% watch television before bed and 48.3% scroll on phones or tablets, even though habits like these have been shown to hinder sleep.

Meanwhile, only 11.6% practice breathing exercises, meditation, or mindfulness, and just 8.8% stretch or do light exercise — despite the fact that health experts recommend these techniques for better sleep.

Practical tactics for enhancing sleep

To help you feel better prepared for sleep, try a few of these simple habits. They may also help improve your overall sense of relaxation and well-being throughout the day.

1. Build in more exercise. If your schedule is overbooked, try to add just a short walk during lunch or after dinner, and a 10-minute stretching session in the morning or evening. Any activity that gets you moving and uses your muscles can help relieve unwanted tension. Keep any exercise in the evening gentle, as vigorous exercise can have effects like raising your heart rate, which may make sleep more difficult.

2. Reduce pre-bedtime eating that can make it harder to fall asleep. Try to avoid heavy meals later in the evening, and cut down on snacking. Both of these habits can disrupt natural circadian rhythms related to sleeping and waking.

3. Put away gadgets like your phone, tablet, and TV at least 60 minutes before bedtime. Too much screen time at night makes it harder for your mind and body to unwind, and make the transition from stimulation to relaxation difficult.

4. Boost your intake of magnesium, particularly magnesium glycinate, which plays a key role in muscle relaxation and supports the body's natural wind-down process. Magnesium also offers overall health benefits like aiding muscle and bone development, muscle and nerve function, blood glucose control, and blood pressure regulation. Many people don't get enough magnesium in their diet.

To help you relax and improve your sleep, consider adding Viactiv^® Magnesium Glycinate Powder to your routine — it provides magnesium in the glycinate form, which is a form known to be gentle on the stomach and easy to absorb. This supplement delivers 200 milligrams of magnesium glycinate per teaspoon in an easy-to-mix, delicious, sugar-free peach flavor. You can make it even easier to boost magnesium intake by replacing your usual post-dinner dessert or snacks with this tasty smoothie:

Peach-Pineapple Wind Down Smoothie

1 teaspoon Viactiv High Absorption Magnesium Glycinate Powder
1/2 cup low-fat Greek yogurt
1/4 cup natural pineapple juice
1/2 cup ice

Combine in a blender, adding a few frozen peach slices if desired.
Blend until smooth and enjoy after dinner as part of your wind-down ritual.

Incorporating some of these habits into your regular evening routine will help support a better sleep experience, which can contribute to your overall well-being.

The Viactiv^® Magnesium Glycinate Powder is available to purchase on Amazon and iHerb. Visit Viactiv.com to learn more about magnesium and other supplements to support your nutritional needs.

*Survey Methodology: Viactiv commissioned Atomik Research to conduct an online survey of 2,000 women age 18 and over throughout the United States. The margin of error is +/- 2 percentage points with a confidence level of 95%. Fieldwork took place between April 21 and April 23, 2026. Atomik Research, part of 4media group, is a creative market research agency.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Key Takeaways:

• Alpha-1 antitrypsin deficiency (Alpha-1) is a genetic disease causing the liver to produce insufficient or dysfunctional alpha-1 protein, which can leave the lungs less protected from infection and pollutants.¹
• Symptoms of Alpha-1 are similar to other respiratory diseases, making the condition difficult to diagnose.²
• Alpha-1 can impact lung health and lead to serious lung diseases like COPD or emphysema.² Risk can be impacted by multiple factors such as levels of Alpha-1, lifestyle and environment.
• People with COPD, people with asthma and airflow obstruction that doesn't fully reverse with treatment and family members of anyone with Alpha-1 should ask about getting tested.²

Daryl Kunz loves distance cycling. By age 54, he had clocked thousands of miles annually, winning a regional championship in a 24-hour bike race and several other medals. He was used to cycling long distances, and considered a "century" (100 miles) an enjoyable outing. But one day, on a brisk 60-mile ride, Daryl began experiencing shortness of breath and wheezing for the first time.

These symptoms led to a multi-year journey of frustration. Doctors prescribed medications for asthma and tested for potential heart conditions, but Daryl was no closer to understanding what was happening.

"I went through four years of searching and changing my lifestyle, making me fear I could potentially lose something I absolutely love doing," said Daryl.

Finally, his pulmonologist tested him for Alpha-1 antitrypsin deficiency (Alpha-1), a rare genetic disease that can impact lung health and cause conditions like chronic obstructive pulmonary disease (COPD).² Daryl was told that his lung capacity was reduced to 58%, and it was likely that his avid cycling helped him to stay as healthy as possible despite his condition.

"Without knowing it, my passion for cycling actually helped slow the damage to my lungs," said Daryl. "This made me realize how lucky I was to receive my diagnosis when I did so I could get back on track."

What is Alpha-1?

Alpha-1 occurs when the body cannot make or use enough alpha-1 antitrypsin,¹ a protective protein made in the liver. This protein travels through the bloodstream to the lungs, where it helps protect lung tissue from damage. When alpha-1 protein levels fall below the normal range, individuals may be at an increased risk for lung disease. This risk may be impacted by several factors, including genetics, lifestyle and environmental exposures.²

It's estimated between 70,000-100,000 people in the U.S. live with severe Alpha-1 but as many as 90% of these individuals aren't diagnosed.³ As one of the most underdiagnosed genetic diseases in the world, it can take as long as eight years to be correctly diagnosed.⁴

• Habits, routines and environmental cues work together to influence your body's natural sleep-wake cycle.
• One of the most important players in that ecosystem is melatonin, which helps signal to your brain that it's time to wind down.
• Better sleep is one of the strongest investments you can make in your health and well-being.

Americans have never been more focused on optimizing their health. They wear devices that measure nearly every aspect of their day — from workouts and steps to heart rate and recovery — and increasingly turn to GLP-1 medications as part of the weight management journey.

Alongside these changes, experts are encouraging people to prioritize another key pillar of health: quality sleep, which plays an important role in overall well-being and can support healthy lifestyle habits.

According to the Centers for Disease Control and Prevention (CDC), more than 30% of U.S. adults regularly get less than the recommended seven to nine hours of sleep each night¹.

Dr. Stephanie Stahl, Medical Director at Indiana University Health, notes that many people still treat sleep as something they'll fit in if there's time. Stahl is the Sleep Medicine Fellowship Program Director and Associate Professor at Indiana University School of Medicine as well as Natrol^® Sleep Science Advisory Board member. "Many people think of sleep as the first thing they can sacrifice when life gets busy. But sleep isn't a luxury. It's one of the most powerful tools we have to support our health, mental well-being and daily performance."

That can be difficult in today's always-on world. Packed schedules, constant notifications and late-night scrolling can all work against the body's natural sleep-wake cycle. In fact, 38% of adults say using their phone or tablet before bed to read the news or "doomscroll" makes their sleep somewhat or significantly worse².

What sleep myths could be keeping you awake?

"One of the biggest misconceptions I hear is that sleep starts when your head hits the pillow," said Stahl. "The truth is that your body has been preparing for sleep all day. Your light exposure, activity, meals, stress and evening routine all influence how prepared your brain and body are for sleep."

She describes this as your sleep ecosystem — the daily habits, routines and environmental cues that work together to influence your body's natural sleep-wake cycle. One of the most important players in that ecosystem is melatonin, a hormone your body naturally produces in response to darkness. Rather than forcing sleep, melatonin helps signal to your brain that it's time to wind down.

Stahl is helping to debunk three common sleep myths:

Myth: Better sleep starts at bedtime.

Stahl: "Great sleep starts the moment you wake up. Morning sunlight helps regulate your body's internal clock and supports natural melatonin production later that evening."

Myth: I'll catch up on sleep this weekend.

Stahl: "Consistency matters more than catch-up sleep. Keeping a regular sleep and wake schedule (yes, even on weekends) helps reinforce your body's natural rhythm."

Myth: The eight hours you're asleep are all that matter.

Stahl: "The hour before bed matters, too. A consistent wind-down routine, like dimming the lights and avoiding screen time, helps prepare your brain and body for quality sleep."

What small habits lead to better sleep?

The good news is that improving sleep doesn't require overhauling your lifestyle. Stahl recommends focusing on a few consistent habits: Get outside for natural light early in the day, stay physically active, avoid caffeine in the afternoon and evening, maintain a regular sleep schedule and create a cool, dark, quiet sleep environment.

When healthy habits need extra support that is safe

Healthy sleep habits are the foundation of better sleep, but even the best routines can't account for everything. Travel, shift work, changing schedules, stress and age-related changes can all temporarily disrupt your body's natural rhythm.

It's one reason more than 27% of U.S. adults report using melatonin supplements, making it one of the country's most commonly used sleep supplements³. Melatonin is a well-studied naturally occurring hormone that plays a key role in regulating the sleep-wake cycle. When used as directed, it is widely recognized as a safe, effective and non-habit-forming option for temporary sleep support. Backed by 30 years of scientific research and widespread use, melatonin is the No. 1 doctor recommended ingredient for sleep⁴, recognized by experts as a safe, reliable way to help people fall asleep faster and stay asleep longer*.

"Healthy sleep starts with healthy habits," says Stahl. "Melatonin is a hormone your body naturally produces to help signal when it's time to sleep. If travel, changing schedules or other temporary disruptions affect that rhythm, melatonin supplements can help support your body's natural sleep-wake cycle. The key is to think of it as one part of a broader sleep strategy, not a replacement for healthy habits."

Because sleep challenges vary from person to person, some people may also benefit from ingredients such as magnesium glycinate, valerian root, GABA or L-theanine depending on their individual needs. Guided by leading sleep experts, including Stahl, Natrol develops science-backed sleep solutions designed to complement healthy sleep habits and support different sleep needs.

The benefits of prioritizing sleep extend well beyond feeling rested — 88% of adults who are satisfied with their sleep, report they are flourishing, compared with just 47% of those who aren't⁵. Better sleep isn't just another wellness goal. It's one of the strongest investments you can make in your overall health and well-being.

* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

SOURCES:

1. Centers for Disease Control and Prevention. Short Sleep Duration Among Adults. National Center for Health Statistics, U.S. Department of Health and Human Services, 2025, https://www.cdc.gov/nchs/products/databriefs/db559.htm. Accessed 26 June 2026.
2. American Academy of Sleep Medicine. "Americans Are Doomscrolling at Bedtime, Prioritizing Screen Time Over Sleep." American Academy of Sleep Medicine, 2025, https://aasm.org/americans-are-doomscrolling-at-bedtime-prioritizing-screen-time-over-sleep/. Accessed 26 June 2026.
3. SleepFoundation.org survey. October 2022. https://www.sleepfoundation.org/sleep-news/how-much-melatonin-do-adults-really-take.
4. Based on a survey of doctors who recommend sleep support products.
5. National Sleep Foundation. Sleep in America^® 2025 Report. National Sleep Foundation, March 2025, https://www.thensf.org/wp-content/uploads/2025/03/NSF_SIA_2025-Report_final.pdf. Accessed 26 June 2026.

At the same time, summer also brings a familiar desire to slow down, minimize everyday distractions and make the most of uninterrupted time outside. Unfortunately, mosquitoes have a way of pulling people out of those moments. Whether it's swatting mosquitoes during a youth sports game, interrupting a conversation on the patio or sending everyone inside sooner than planned, even small interruptions caused by mosquitoes can make it harder to simply enjoy being outside and may cause some to head indoors instead.

The good news? Mosquito protection and quality time outdoors don't have to be complicated. Understanding where mosquitoes can show up and creating a mosquito protection zone before everyone settles in can help keep summer escapes on track.

According to Dr. Tom Mascari, entomologist at the SC Johnson Center for Insect Science, "Mosquitoes can develop in surprisingly small amounts of water, as little as a tablespoon. I think of mosquito control as a layered approach: be aware of breeding sites, protect the spaces where you spend time outdoors, and take additional steps when needed."

To keep the focus on enjoying summer, Dr. Mascari shares a few simple habits to keep mosquitoes from ruining the summer fun:

1. Check the mosquito forecast before making outdoor plans.

Planning a cookout, picnic or evening at the park? Before heading outside, check your local OFF!Cast Mosquito Forecast. By entering a ZIP code, it provides a seven-day forecast of mosquito activity in your area to help people better plan around their outdoor activities. The forecast uses weather data powered by The Weather Company and was validated by mosquito data from thousands of U.S. locations.

2. Know when mosquitoes are most active.

Many mosquito species are most active at dusk and dawn — the same time families are often enjoying time on the patio, taking evening walks or spending time at youth sports games. It's important to be mindful of these peak mosquito hours and plan accordingly to help stay protected from mosquito bites.

3. Create a mosquito protection zone around the places you gather.

An easy way to reduce mosquito bites is to protect the space around you before mosquitoes become a nuisance. Although on-skin repellents are a good option, some consumers prefer solutions that don't require skin application. Area repellents can help create a protective zone around patios, picnic blankets, sports sidelines and other shared outdoor spaces before mosquitoes interrupt the moment.

New this season, OFF!^® Area Repellent is the bug spray you don't put on — offering fast and easy zone coverage that keeps mosquitoes six feet away for up to six hours when used as directed. Voted the 2026 Product of the Year USA winner in the Outdoor Mosquito Repellent category[3], OFF!^® Area Repellent offers a convenient way to help protect shared outdoor spaces.

With a simple spray that creates a protective zone around outdoor areas, it delivers effective, portable mosquito protection around patios, picnic blankets, campsites, sports sidelines and more so mosquitoes don't interrupt your personal space when outdoors.

4. Dress smart.

Wearing long sleeves and long pants provides a physical barrier that can make it harder for mosquitoes to reach your skin. Light-colored fabrics are also especially helpful because mosquitoes are generally more attracted to darker colors.

5. Don't forget the fan.

Whether you're hosting in the backyard or heading to the park or sports sidelines, a portable fan can do more than help everyone stay cool on hot summer days; they can also help make outdoor spaces less inviting to mosquitoes.

According to Dr. Tom Mascari, "Mosquitoes aren't particularly strong fliers, so increasing airflow around patios and outdoor seating areas can make it harder for them to land."

From neighborhood cookouts and park picnics to cheering from the sidelines, simple mosquito prevention habits can go a long way. By planning ahead, dressing for the occasion and creating a mosquito protection zone with OFF!^® Area Repellent you can spend less time swatting bugs and more time making the memories that define summer.

For more information about OFF!^® Area Repellent and to check your local mosquito forecast, visit OFF.com.

If your dry eye symptoms are affecting how you view your emotional health and well-being, don't wait to talk to your eye doctor. There are various options available that can help provide relief. Learn more at KnowYourDryEye.com.

• As America celebrates 250 years of freedom, it's time to honor the veterans, service members, and their loved ones who have made it possible.
• Wounded Warrior Project^® (WWP) has helped veterans like Mark Lalli (pictured above) find career counseling and mental health support after leaving service.
• Find out how you can do your part to honor and support service members and their families now and forever.

For 250 years, the courage, resilience, and strength of service members and their families have shaped the country and secured the promise of freedom — past, present, and future. Whether they're Army, Navy, Marines, Air Force, Coast Guard, or Space Force, they share the same commitment and contribution to American strength.

For many veterans and service members, joining the military is more than a calling — it's a legacy.

"From the Revolution through now, I had somebody in my family serving," said Army veteran Mark Lalli. "I have my great-grandfather's dog tags from World War I. My maternal grandfather did seven invasions in the Pacific, and my paternal grandfather served in Europe."

This is just one story of millions that underscores how service members and their loved ones have made America's 250th anniversary of independence possible. However, these contributions often come at a personal cost that many warriors contend with in and out of uniform.

"From one generation to the next, warriors have answered the call to defend our freedoms," said WWP^® CEO Walt Piatt. "It's our duty to ensure they're never left to carry the cost of that service alone."

The visible and invisible wounds of service

Thirteen months after the 9/11 attacks, Lalli joined the U.S. Army to honor his family's military heritage and desire to protect his country. He eventually became a Black Hawk crew chief, serving as a mechanic and combat gunner.

During a training exercise in Italy, Lalli's military service was cut short when his helicopter crashed, killing six of the soldiers on board and leaving Lalli with severe injuries. Returning to civilian life, he faced uncertainty, physical challenges, post-traumatic stress disorder, and a loss of the close bonds he had relied on.

Lalli's challenges aren't uncommon. According to the WWP Warrior Survey:

• 76% of warriors report that pain interferes moderately or severely with their enjoyment of life.
• 63% of warriors reported symptoms of one or more mental health conditions, including PTSD.
• 79% of warriors report that they sometimes or often feel isolated, and 72% feel they lack companionship.

These seen and unseen wounds create barriers for service members to thrive. However, organizations and individuals have stepped up to support the ongoing and evolving care needs of veterans, service members, and their loved ones.

Supporting a brighter future for service members

Lalli's path to healing and support started when he got connected with WWP.

"I first met Wounded Warrior Project when an outreach coordinator came to visit me in the hospital," Lalli said. "He showed me that it's not the end and inspired me to believe that anything is still possible."

By participating in WWP programs and events, like Soldier Ride^® — a multiday adaptive cycling event — Lalli recovered a sense of community, confidence, and hope.

"Being on Soldier Ride brings back the camaraderie and tribe mentality that we had in the military," Lalli recalled. "It's how the environment and being together help each of us bring out the best in one another. It has helped me reignite my drive and has helped me work harder at being the best father, husband, and friend I can be to those around me."

This is just one example of how WWP supports veterans, service members, and their families across every stage of life and service. The nonprofit strives to help warriors rebuild connections, regain confidence, and move forward after their military service. To that end, WWP programs are designed to meet warriors where they are.

Wounded Warrior Project stands by our nation's heroes no matter what — keeping the promise to bring every warrior home, mind, body, and soul.

For some, like Lalli, that means connecting veterans with community after isolation. For others, it can mean help navigating mental health challenges, support for improving physical well-being, or resources to strengthen family support. This important work ensures that warriors past and present have what they need — not just to get by, but to thrive. WWP remains committed to that mission for years to come.

How you can help warriors thrive for a lifetime

As the U.S. celebrates 250 years of freedom, it's time to give back to those who have served, are serving, and will continue to serve to protect that freedom. Supporting and empowering service members, their families, and caregivers is a shared responsibility that reflects the values that define America.

"Wounded Warrior Project stands by our nation's heroes no matter what — keeping the promise to bring every warrior home, mind, body, and soul," Piatt said. "Caring for those who sacrificed to protect us is a privilege and responsibility we all share."

To learn more about how you can be part of the next 250 years of strength, resilience, and service and support the nation's warriors today and always, visit WoundedWarriorProject.org/250Anniversary and WoundedWarriorProject.org/Donate.

IT'SUGAR — one of the world's largest specialty candy retailers — has partnered with Make-A-Wish^® to bring joy and hope to children living with critical illnesses and their families. As part of this collaboration, IT'SUGAR will sell its exclusive Make-A-Wish^® Wish Pops to raise funds for the organization. When you buy one (or more!) of these rainbow star-shaped lollipops, 20% of your purchase will be donated to Make-A-Wish^®, supporting the organization's mission to grant life-changing wishes to children who need them the most. Nothing is sweeter than that.

Sweet things should do good things

Since 2019, IT'SUGAR has partnered with Make-A-Wish^® to support the organization's vision to grant the wish of every eligible child. Known for its over-the-top candy experiences, pop culture collaborations and trend-driven sweets, the candy retailer has sold limited-edition candies like its Make-A-Wish^® Wish Pops and hosted special events to raise funds for wish kids everywhere.

Earlier this year, IT'SUGAR celebrated a $2 million donation milestone during the Miami leg of the "WishMakers Wanted Mosaic Tour" at its Bayside Miami store. During the interactive event, hosted in partnership with Royal Caribbean, community members were invited to contribute to a growing digital mosaic of photos and messages from WishMakers across the country. The Miami WishMakers Wanted event also included a special mission moment with wish alum Kayden, community engagement activities and participation by Royal Caribbean employees in a Walk for Wishes^® leading up to the store.

What's a WishMaker? Anyone who takes action for wish kids through fundraising, volunteering, donating and more can become a WishMaker. Make-A-Wish^® estimates that more than 50 WishMakers play a part in every wish by donating their time, talent or treasure. Wish experiences aren't just moments of fun. Research shows that wishes have the power to help build the physical and emotional strength children need to fight a critical illness.

Be part of something sweet

Every 20 minutes, a family learns their child has been diagnosed with a critical illness, but you can help make their days a little sweeter. This year, celebrate National Lollipop Day by grabbing a sweet treat while also bringing joy to a child and their family. To learn more and help make a difference in a child's life, visit your local IT'SUGAR location or visit ItSugar.com.

At its simplest, sparkling milk pairs milk with light carbonation, creating a drink that sits somewhere between soda and a creamy refresher. And while it's not an entirely new concept, sparkling milk has been increasingly showing up across social feeds, café menus and even in grocery stores — turning a familiar staple in the fridge into something unexpected and fun!

Read on for five delicious sparkling milk recipes that can help hydrate and satisfy those afternoon cravings. And here's a recipe tip: you can get a boost of protein when you use the new Organic Valley^® Protein Plus™ Ultra-Filtered Milk — a new line of ultra-filtered, pasture-raised organic milk with 50% more protein and 50% less sugar than regular milk*.

So grab a carton of organic milk and your carbonated water machine and have fun experimenting with these sparkling milk beverage recipes. Cheers!

Sparkling Orange Cow Milk

This sparkling milk recipe is a bubbly twist on the nostalgic, creamsicle-flavored beverage, Orange Cow. It delivers sprightly sips by combining sweet citrus meets smooth milk, while the bubbles keep each sip feeling light and lively.

1/2 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/2 cup orange juice

2 teaspoons simple syrup

1/2 teaspoon vanilla extract

Combine milk, simple syrup and vanilla extract into a liquid measuring cup; top with OJ and pour all of the ingredients into the carbonated water machine bottle. Press the carbonation button for 2–3 seconds (shorter time for smaller bottles and depending on how bubbly you like your beverages). Pour into a glass with ice and enjoy!

Coconut Lime Sparkling Milk

Creamy, tropical and bright, Coconut Lime Sparkling Milk brings a fresh take on a beach-inspired favorite. Smooth coconut blends with crisp lime — perfect for sunny afternoons or whenever you want a mini escape in a glass.

1/2 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/2 cup unflavored sparkling water (option: swap in a coconut or lime-flavored sparkling water and this can be made with your carbonated water machine or store bought)

1 1/2 to 2 tablespoons coconut syrup

1/2 lime, cut into wedges

Combine milk, sparkling water and coconut syrup into a liquid measuring cup. Squeeze in two lime wedges. Pour the mixture into the carbonated water machine bottle and carbonate for 2–3 seconds. Pour into a glass — we recommend adding ice, too — and enjoy. Add a little flair by decorating the rim of the glass with a lime wedge or a mini umbrella!

Strawberry Shortcake Sparkling Milk

Sweet, bright and lightly fizzy, Strawberry Shortcake Sparkling milk turns a classic dessert into a refreshing drink. It blends the flavor of ripe strawberries and vanilla cake with creamy milk and a gentle sparkle for a fun twist. It has a nostalgic charm that feels right at home on warm days or casual get-togethers.

1/2 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/2 cup strawberry flavored sparkling water (this can be made with your carbonated water machine or store bought)

1/4 cup strawberries, diced

2 tablespoons condensed milk

1/2 teaspoon simple syrup

1/2 teaspoon vanilla extract

Optional: splash of strawberry syrup

Muddle 1/4 cup fresh strawberries and pour into an 8-ounce glass. Combine milk, sparkling water, condensed milk, simple syrup and vanilla extract in a liquid measuring cup. Pour the mixture into the carbonated water machine bottle and carbonate for 2–3 seconds. Place ice cubes into your glass with the muddled strawberries, pour the sparkling milk recipe into the glass and then enjoy the strawberry sweetness in every fizzy sip!

Cake Batter Sparkling Milk

This sweet and creamy recipe might bring back memories of a childhood birthday! Cake Batter Sparkling Milk brings the flavor of birthday cake into a fizzy, sippable treat that is perfect for celebrations or anytime you want something fun and festive to drink. This recipe is milk-forward but you can always cut it in half if you want a lighter option by reducing the milk by a half cup and instead, adding a half cup of sparkling water.

1 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/2 teaspoon simple syrup

1/2 teaspoon brown sugar

1 teaspoon vanilla extract

Optional: 2 tablespoons condensed milk

Combine all ingredients in a liquid measuring cup. Pour the mixture into the carbonated water machine bottle and carbonate for 2–3 seconds. Pour into a glass with ice, then sit back and celebrate — birthday or not!

Espresso Sparkling Milk

Put a spin on your morning coffee routine or bring a lively twist to your afternoon pick-me-up with this effervescent Espresso Sparkling Milk recipe. A cross between an iced latte and a soda, this recipe offers the option of combining milk with either shots of espresso or cold brew coffee, as well as making it a caffeinated or decaffeinated beverage.

Recipe Option 1:

1/2 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/4 cup unflavored sparkling water (this can be made with your carbonated water machine or store bought)

2 shots of espresso

Splash of your favorite flavored coffee creamer

Recipe Option 2:

1/2 cup Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk

1/2 cup cold brew coffee

Splash of your favorite flavored coffee creamer

Combine all ingredients in a liquid measuring cup. Pour the mixture into the carbonated water machine bottle and carbonate for 2–3 seconds. Pour into a glass with ice and savor your newest coffee creation!

You can add a little extra flavor to either recipe by topping off your sparkling coffee beverage with a splash of a flavored coffee creamer, like Organic Valley^® French Vanilla Flavored Coffee Creamer or Organic Valley^® Sweet Cream Flavored Coffee Creamer.

Sparkling milk may have started as a curious idea, but it is quickly becoming a creative way to rethink an everyday favorite that can feel both familiar and a little more playful. And, when you use Organic Valley^® Protein Plus™ Ultra-Filtered Milk you can increase your protein intake, along with your bubbles!

Want to learn more about milk? Below are a few more articles to consider reading while you enjoy your glass of sparkling milk:

The Nature of Protein: From Soil to Milk

Is Milk a Protein or Carb?

What Is This About Cow's Milk Hydrating Better Than Water?

Inspired to try other milk beverage recipes? Read more here: 5 Nourishing Milk Drink Recipes to Fill Your Cup Naturally

* Organic Valley^® Protein Plus™ Whole Ultra-Filtered Milk has 10% more of the daily recommended value for protein than regular whole milk; the protein content of regular whole milk is 8 grams per serving; Organic Valley^® Protein Plus™ Whole Ultra-Filtered Milk has 13 grams of protein per serving. Organic Valley^® Protein Plus™ Whole Ultra-Filtered Milk has 50% less sugar than regular whole milk. The sugar content of regular whole milk is 12 grams per serving. Organic Valley^® Protein Plus™ Whole Ultra-Filtered Milk has 6 grams per serving.

* Organic Valley^® Protein Plus™ Reduced Fat Ultra-Filtered Milk has 10% more of the daily recommended value for protein than regular reduced fat milk; the protein content of regular reduced fat milk is 8 grams per serving; Organic Valley^® Protein Plus™ Reduced Fat Ultra-Filtered Milk has 13 grams of protein per serving. Organic Valley^® Protein Plus™ Reduced Fat Ultra-Filtered Milk has 50% less sugar than regular reduced fat milk. The sugar content of regular reduced fat milk is 12 grams per serving. Organic Valley^® Protein Plus™ Reduced Fat Ultra-Filtered Milk has 6 grams per serving.

* Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk has 10% more of the daily recommended value for protein than regular fat free milk; the protein content of regular fat free milk is 8 grams per serving; Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk has 13 grams of protein per serving. Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk has 50% less sugar than regular fat free milk. The sugar content of regular fat free ultra-filtered milk is 12 grams per serving. Organic Valley^® Protein Plus™ Fat Free Ultra-Filtered Milk has 6 grams per serving.

From longer run times to increased energy use, heat waves can impact how an air conditioner operates. Knowing why this happens and what steps can support system performance can help homeowners stay comfortable all summer long.

Extreme heat creates greater demand on cooling systems

Air conditioners cool homes by removing heat from indoor air and transferring it outside. As outdoor temperatures rise, that process becomes more challenging. The larger the difference between indoor and outdoor temperatures, the harder the system must work to maintain comfort.

Most residential air conditioning systems are designed to operate efficiently under typical seasonal conditions. During prolonged periods of extreme heat, however, homeowners may notice longer cooling cycles, higher energy consumption and less dramatic temperature reductions during the hottest hours of the day.

In many cases, these longer run times are normal. Rather than cycling on and off frequently, a properly functioning system may run continuously during peak afternoon hours to maintain consistent indoor temperatures and humidity levels. However, if a homeowner's system frequently struggles to keep up during extended periods of extreme summer heat, it may be time to consider an upgrade. For example, the Ruud^® RP17AY Endeavor^® Universal Heat Pump features a variable-speed compressor with inverter technology that adjusts output to match your home's cooling needs. Instead of repeatedly cycling on and off like traditional systems, it operates at lower, more precise speeds to deliver steady comfort, better humidity control and improved energy efficiency — all while helping reduce power spikes.

Maintaining strong airflow for consistent comfort

One of the most common reasons an air conditioner struggles during hot weather is restricted airflow.

Dirty air filters, blocked vents and clogged ductwork can prevent conditioned air from circulating properly throughout the home. When airflow is restricted, the system must work harder to deliver the same level of comfort, increasing strain on components and reducing overall efficiency.

Homeowners should inspect air filters regularly throughout the cooling season and replace them according to manufacturer's recommendations, using the correct filter type and MERV rating for their system. It's also important to ensure that the supply and return vents remain open and unobstructed by furniture, rugs or other household items.

Proper airflow allows the system to operate as designed and can help improve cooling performance during periods of extreme heat.

Maintenance and equipment age play a critical role

Like any mechanical system, air conditioners require routine maintenance to perform at their best. Over time, normal wear and tear can impact efficiency and reliability. Dirty coils and worn components can reduce a system's ability to meet cooling demands when temperatures soar.

Regular professional maintenance helps identify and address potential issues before they become larger problems. Seasonal inspections can also help ensure the system is operating safely and efficiently before the hottest days of summer arrive.

Equipment age can also influence performance. Older systems often operate less efficiently than newer models and may struggle to maintain comfort during extended heat waves. Homeowners with aging equipment may benefit from consulting a trusted HVAC contractor to determine whether repairs, upgrades or replacement options are appropriate. Working with a qualified contractor, such as a member of the Ruud Pro Partner^® network, can help homeowners receive expert guidance on maintaining, repairing or upgrading their system to support comfort and efficiency throughout the cooling season.

Humidity and indoor heat sources

Temperature is only part of the equation for indoor comfort. Air conditioners also help remove moisture from the air. During periods of high humidity, systems must work harder to both cool and dehumidify the home. Excess humidity can make indoor spaces feel warmer than the thermostat reading suggests, leading homeowners to lower temperature settings and increase system workload.

Making sure the home is free of leaks around doors and windows and access points to attics and unconditioned basements can help control the influx of unwanted humidity issues. In some cases, standalone dehumidifiers can be used to tackle the humidity, putting less work on the AC unit.

Everyday household activities can also contribute additional heat. Cooking, running clothes dryers and operating other appliances can raise indoor temperatures, forcing the air conditioner to work even harder. Simple measures such as keeping blinds closed during peak sunlight hours, limiting heat-producing activities during the hottest parts of the day, and ensuring windows and doors remain closed can help reduce cooling demand and support overall system performance.

Staying comfortable when temperatures rise

While no air conditioning system is immune to the challenges of extreme weather, homeowners can take proactive steps to help maximize comfort and efficiency during a heat wave.

Regular filter changes, routine professional maintenance, unobstructed airflow and smart temperature management can all help reduce strain on cooling equipment. Homeowners should also recognize that longer run times during extreme heat are often a sign that the system is actively working to maintain comfort, not necessarily that something is wrong.

By understanding how heat waves affect air conditioning performance and taking steps to support system operation, homeowners can help keep their homes comfortable while minimizing unnecessary wear on their HVAC equipment throughout the summer.

Patient stories reflect the real-life experiences of persons diagnosed with hemophilia A who have been prescribed ALTUVIIIO. However, individual experiences may vary. Patient stories are not necessarily representative of what another person using ALTUVIIIO may experience.

For Eli, soccer has always been more than just a sport. From the moment he first touched a ball at age 4, it became his language for connecting with the world. Every kick, every save, and every sprint wasn't just about the game — it was about discovering where he belonged.

As a goalkeeper, Eli found his calling in the rush of a save, the trust his teammates placed in him, and the feeling of being part of something bigger than himself. Soccer gave him something that he couldn't find anywhere else: a sense of purpose and belonging that went far beyond the field.

"Soccer is a good team game," Eli said. "It brings you together with people, and even when you're alone, you can go out there by yourself and kick the ball around."

Now, with the world's eyes focused on soccer's biggest stage, Eli reflects on a journey that's been anything but ordinary. Living with hemophilia A has woven itself into every chapter of his soccer story, from his first steps onto the field to the ambitious goals he's still chasing today, both as a player and as a person determined to show others what's possible.

Growing up with hemophilia A — on and off the field

Hemophilia A is a rare bleeding disorder in which the blood doesn't clot properly. For the approximately 33,000 people living with it in the United States, that reality touches every part of life.¹ From spontaneous bleeding to joint damage and chronic pain, hemophilia A is a condition that often requires lifelong management.¹

"I always felt different because I knew I had a bleeding disorder, so there were some things I had to be more mindful of," Eli said. "But I learned to manage it, and I still ended up doing a lot of the things that the other kids did."

And the one thing he refused to give up along the way? Soccer.

As one of the most unique, yet critical, positions on the field, playing goalkeeper required Eli to be thoughtful about how he could protect himself. For Eli, injuries weren't just setbacks, they also meant time away from the game he loved. Whether it meant wearing protective gear or talking with his doctor about a treatment plan that would allow him to pursue his goals, he continued to find ways to stay connected to the sport he loves.

"With soccer, I knew I had an active lifestyle," Eli said. "I needed a treatment that would keep up with my life and not hold me back from doing the things I wanted to do."

For Eli, managing hemophilia A was never about limitations. It was about finding the right tools to stay in the game, on his own terms.

Pursuing goals for real life

As Eli got older, his life became busier and more independent. Suddenly, Eli wasn't just managing hemophilia A around soccer practice and school. He was navigating a full, fast-paced life that included classes, work shifts, fraternity events, early morning gym sessions and weekend pickup soccer games of course. His days were packed and entirely his own to decide.

That shift also changed how he thought about treatment.

"When I first sat down to consider my treatment goals, the things that mattered most to me were: Am I going to be happy, and am I still going to be able to do the things I want to do every day?" Eli said. "I needed a treatment that helped keep me protected during daily life."

For Eli, that meant a shift in perspective. He was now thinking beyond a single game, practice or activity and instead looking for protection that could support his active routine, without becoming the center of it. For someone balancing college, fitness and travel, protection was just as important as convenience.

Finding a treatment routine that could fit into his lifestyle

After talking with his doctor, Eli made a decision: He started ALTUVIIIO^® [antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl], a once-weekly factor replacement therapy that is used to control and reduce the number of bleeding episodes in people with hemophilia A. As with all factor VIII therapies, ALTUVIIIO may cause side effects and carries a risk of hypersensitivity reactions and inhibitor development. The most common side effects reported in clinical studies were headache and joint pain.²

"At first, switching to a different medicine can definitely be hard because you are comfortable with what you have," Eli said. "But for me, it was worth it."

For Eli, part of what made ALTUVIIIO a good fit wasn't just the once-weekly dosing, though that mattered. It was knowing that his factor VIII levels could stay higher in his body for longer, which was important to him as he thought about the activities and responsibilities ahead in his week. For someone juggling college, work, the gym and an active social life, that mattered.

Playing the long game

Although Eli now balances soccer alongside other priorities, it's still woven into the fabric of who he is. As a long-time fan of major soccer events, this summer holds special meaning as he watches the world come together to celebrate the game that shaped him, cheering for players chasing the same dreams he once had.

But his experience with hemophilia A shaped more than how he stayed in the game; it also helped show him what he wanted to do with his life. Today, Eli is studying sports medicine, building a career where he can help others reach their health and performance goals.

"Growing up with something like hemophilia, it becomes part of how you see the world," Eli said. "I've been around sports, injuries and recovery my whole life, so sports medicine feels like a natural fit for me."

Eli has also served as a counselor at a summer camp managed by the Louisiana hemophilia community, where he gets the chance to spend time with younger kids navigating the same condition he's lived with since infancy. Those conversations aren't just about sharing advice — they're about showing what's possible. While hemophilia doesn't have to define Eli or anyone else, it does require understanding and management.

This summer, as the world watches soccer's biggest stars chase their glory, Eli is chasing something just as meaningful: graduating college, staying active, and building a future where he can help others do the same.

"I know what it feels like to be the kid who wants to get out there and play," Eli said. "I want other young people with hemophilia to know they can take care of themselves and still keep going after the things they love."

For Eli, the game was never just about soccer. It was always about chasing what comes next.

INDICATION:

ALTUVIIIO^® [antihemophilic factor (recombinant), Fc-VWF-XTEN fusion protein-ehtl] is an injectable medicine that is used to control and reduce the number of bleeding episodes in people with hemophilia A (congenital Factor VIII deficiency).

Your healthcare provider may give you ALTUVIIIO when you have surgery.

IMPORTANT SAFETY INFORMATION

What is the most important information I need to know about ALTUVIIIO?

Do not attempt to give yourself an injection unless you have been taught how by your healthcare provider or hemophilia center. You must carefully follow your healthcare provider's instructions regarding the dose and schedule for injecting ALTUVIIIO so that your treatment will work best for you.

Who should not use ALTUVIIIO?

You should not use ALTUVIIIO if you have had an allergic reaction to it in the past.

What should I tell my healthcare provider before using ALTUVIIIO?

Tell your healthcare provider if you have had any medical problems, take any medications, including prescription and non-prescription medicines, supplements, or herbal medicines, are breastfeeding, or are pregnant or planning to become pregnant.

What are the possible side effects of ALTUVIIIO?

You can have an allergic reaction to ALTUVIIIO. Call your healthcare provider or emergency department right away if you have any of the following symptoms: difficulty breathing, chest tightness, swelling of the face, rash, or hives.

Your body can also make antibodies called "inhibitors" against ALTUVIIIO. This can stop

ALTUVIIIO from working properly. Your healthcare provider may give you blood tests to check for inhibitors.

The common side effects of ALTUVIIIO are headache and joint pain.

These are not the only possible side effects of ALTUVIIIO. Tell your healthcare provider about any side effects that bothers you or does not go away.

Please see Full Prescribing Information

Please consult your healthcare professional if you have any questions about your health or treatment.

To learn more about Eli and his ALTUVIIIO story visit www.altuviiio.com/us/patient-stories.

References

1. Centers for Disease Control and Prevention. Data and Statistics on Hemophilia. https://www.cdc.gov/hemophilia/data­-research/index.html. Accessed June, 2026.
2. ALTUVIIIO^®. Prescribing information. Sanofi; 2025. Accessed June, 2026. https://products.sanofi.us/altuviiio/altuviiio.pdf

© 2026 Sanofi. All rights reserved. All trademarks mentioned are the property of the Sanofi group. MAT-US-2606893-v.1.0-07/2026

For Jennifer Etienne, 27, what began in her teens as irritation on her hands slowly became a painful, persistent condition that affected nearly every part of her daily life. Her hands often became swollen, blistered, and cracked — sometimes so raw that even light touch caused burning.

While Jennifer was diagnosed with eczema at 8 years old, she first noticed symptoms typical of chronic hand eczema (CHE) when she was about 15. After seeing a physician, she was told it was simply eczema. At the time, she didn't realize that eczema affecting the hands can sometimes present differently or become chronic over time.

"I didn't realize the eczema I was experiencing was actually CHE," Jennifer says. Although she was initially diagnosed with eczema, she didn't know that hand eczema can present differently — or that symptoms could persist, recur, or worsen over time.

Over the years, everyday tasks became increasingly painful. "Simple things most people don't think twice about — like washing dishes or using cleaning products — could be incredibly uncomfortable," she explains. "Sometimes it felt like anything that touched my hands made the irritation worse." Because hands are so visible, she often felt self-conscious meeting new people and shaking hands. During CHE flares, she avoided physical contact out of concern that fragrances or lotions worn by others might aggravate her symptoms.

"CHE is more than a skin issue," she says. "It also affects how you live, work, and connect with people."

For many adults, ongoing irritation on the hands may be attributed to frequent handwashing or exposure to soaps and other everyday irritants.¹ But for some, these symptoms may signal something more serious: chronic hand eczema (CHE).

CHE is a persistent or recurrent form of eczema that affects the hands and wrists.¹ It can cause redness, itching, swelling, painful cracking, blistering, and even bleeding.² When symptoms last for more than 3 months or recur frequently they may indicate chronic hand eczema (CHE) rather than temporary irritation.¹

Research suggests that approximately one in ten adults in the United States may be living with CHE,³ making it more common than many people realize.

Beyond visible symptoms, CHE can carry substantial functional and emotional burdens. Studies show that it may significantly impact quality of life, one's occupational choices, work productivity, and daily activities.^4,5

Like many individuals with CHE, Jennifer relied heavily on moisturizers for years and went through periods without consistent medical guidance. Feeling dismissed early in her journey made it harder to seek follow-up care. Eventually, when her symptoms worsened again, she chose to pursue further evaluation by a dermatologist and learn more about her condition.

"Looking back, I wish I had known sooner that if hand symptoms are ongoing, recurrent, or interfering with daily life, it's important to talk to a dermatologist," Jennifer says.

Dermatologists note that because hand eczema can have multiple triggers and may resemble other skin conditions, it can sometimes be overlooked or misunderstood.¹ Recognizing persistent or recurrent symptoms and discussing them openly with a healthcare provider is an important step toward proper evaluation.

To learn more about the symptoms and possible risk factors of CHE, visit www.LearnAboutCHE.com.

*In the photo above, Jennifer participates in advocacy efforts on Capitol Hill as a National Eczema Association ambassador.

References

1. Thyssen JP, Schuttelaar MLA, Alfonso JH, et al. Guidelines for diagnosis, prevention, and treatment of hand eczema. Contact Dermatitis. 2022;86(5):357-378.
2. Molin S, Fargnoli MC, Crépy MN, et al. Real-world evidence of self-reported treatments, signs, and symptom burden in chronic hand eczema: Findings from the multinational CHECK study. Acta Derm Venereol. 2026;106:adv44493.
3. Chovatiya R, Balu S, Bin Sawad A, et al. Prevalence of self-reported physician diagnosis of chronic hand eczema in adults: A cross-sectional study of more than 10,000 participants in the general population – Results from the CHECK study in the United States. Presented at the Fall Clinical Dermatology Conference 2025. Orlando, Florida. 06-08 Nov. Poster Presentation.
4. Simpson E, Balu S, Bin Sawad A, et al. The impact of chronic hand eczema on occupation, work productivity, and activity impairment: Results from the CHECK study in the United States. Presented at the Fall Clinical 25 Annual Congress 2025. September 2025. Poster Presentation.
5. Cortesi PA, Scalone L, Belisari A, et al. Cost and quality of life in patients with severe chronic hand eczema refractory to standard therapy with topical potent corticosteroids. Contact Dermatitis. 2014;70(3):158-168.

At first, it may seem like a small annoyance. You hold a menu a little farther away. You increase the font on your phone. You step into brighter light to read a label at the store. You keep reading glasses easily accessible, in your purse, car, desk drawer and kitchen, just in case.

If any of that sounds familiar, you're not alone. These everyday "workarounds" can be signs of presbyopia, a change in vision that makes it harder to see things up close. And while it's a natural part of getting older for many, it can still add a lot of fuss to routines that used to feel like simple daily tasks.

"Many patients are surprised by how significantly presbyopia can affect their daily lives," said Dr. Melissa Barnett, OD, FAAO, FSLS, FBCLA. "My patients tell me that they find themselves adjusting lighting, increasing font size or relying on workarounds to read more clearly. Presbyopia may be a normal part of aging, but that does not make its impact insignificant for the person experiencing it."

Why close-up vision changes with age

Presbyopia is a common change in vision that makes it harder to see close-up objects clearly. In fact, according to the American Optometric Association, about 9 in 10 adults in the U.S. age 45+ are affected by presbyopia.

It is most often caused by changes in the eye due to aging. These changes usually happen around age 40, when the lens in our eyes begins to stiffen. Over time, this stiffening makes it harder to focus on close-up objects like text messages, menus or fine print.

Common signs and symptoms of presbyopia can include headaches after reading for periods of time, eye strain after close-up tasks like computer work, dizziness, difficulty seeing at night and trouble seeing in dim lighting.

Understanding your options

There is no one-size-fits-all approach to managing blurry close-up vision. Traditional approaches such as glasses (readers, bifocals, progressive lenses) or contact lenses (multifocal or monovision) may work well for some. Others may find them inconvenient or difficult to adjust to and consider surgical procedures to reshape the eye or replace the lens. For adults looking for less invasive options that can fit into daily life, prescription presbyopia eye drops may be worth exploring.

John Hovanesian, M.D., FACS, of Harvard Eye Associates, adds, "Some of my patients do well with reading glasses or other vision correction options, while others are frustrated with the daily workarounds of presbyopia and are looking for a new approach. That's why it's important for you to have a conversation with your eye doctor about daily habits and visual needs, in addition to receiving an eye exam, so you can find the best option for you."

A prescription presbyopia eye drop option

YUVEZZI™ (carbachol and brimonidine tartrate ophthalmic solution) 2.75%/0.1% is a once-daily prescription eye drop for presbyopia, or blurry close-up vision due to age, that can be used your way. It can be used on its own instead of reading glasses or with contacts or glasses you use to see far away.*

In medical studies, YUVEZZI provided up to 8 continuous hours of improved close-up vision.^† As soon as 30 minutes after taking YUVEZZI, some people could clearly read at least 3 more lines on an eye chart in low light without losing distance vision.

In medical studies, the most common side effects of YUVEZZI were headache, impaired vision and, upon instillation, eye pain and/or eye irritation. Patients should not use YUVEZZI if they are allergic to any of its ingredients or if you currently have inflammation of the iris (iritis).

In medical studies, most side effects were generally mild, didn't last long, and went away on their own.

*If you wear contact lenses, remove them before using YUVEZZI. Wait at least 10 minutes after using YUVEZZI before you put them back in your eyes.

^†About half of people in medical studies could read close-up at hour 8.

Learn more

If blurry close-up vision is adding more fuss to your day, it may be time to discuss with an eye doctor to learn more and see if YUVEZZI is right for you. For more information and resources, and to find an eye doctor who treats presbyopia near you, visit www.YUVEZZI.com.

USE

YUVEZZI is a prescription eye drop for adults with blurry close-up vision due to age.

IMPORTANT SAFETY INFORMATION

Do not use YUVEZZI if you are allergic to any of its ingredients or if you currently have inflammation of the iris (iritis).

Before taking YUVEZZI, tell your doctor if you have depression, low blood pressure, or circulation problems.

YUVEZZI may cause temporary blurry, dim, or dark vision. If you experience this, avoid driving, using machinery, and participating in hazardous activities. Use caution when night driving and in other activities in low light.

Call your doctor right away if you suddenly have flashes of light, floaters, or vision loss.

Do not let the tip of the vial touch your eye, eyelid, or any other surface.

The most common side effects of YUVEZZI are headache, impaired vision, and eye pain and/or eye irritation upon use. These are not all of the possible side effects of YUVEZZI.

Most side effects were generally mild, didn't last long, and went away on their own.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see the Brief Summary for more information.

MAT-US-YZ-0355

YUVEZZI is a trademark of Visus Therapeutics, Inc. Visus Therapeutics, Inc., is an affiliate of Tenpoint Therapeutics, Ltd., Warren, NJ 07059 USA. All other trademarks and brands are the property of their respective owners. Use of them does not imply any affiliation with or endorsement by them.

During military and patriotic holidays in 2026, the Salute to Veterans Series shares the stories of veterans who served their country, overcame personal challenges in life and made a positive difference in their communities.

National TV series and year-round program honors veterans spanning several generations, highlights lessons learned when transitioning from the military to civilian life and what it means to serve our nation.

In the 250th year since our nation's founding, the Salute to Veterans Series will air during military/patriotic holidays in 2026, covering the top issues veterans face daily. Terry Bradshaw, Hall of Famer and co-host of Fox NFL Sunday, serves as host of the Salute to Veterans Series, presented by Navy Federal Credit Union and Verizon. Veterans featured in the Salute to Veterans Series include Rocky Bleier, U.S. Army (Ret.), Col. Gregory D. Gadson, U.S. Army (Ret.), Lt. Joe Cardona, U.S. Navy Reserve Officer, Capt. Alejandro Villanueva, U.S. Army (Ret.) and more.

Salute to Veterans is a national television series and year-round program that honors and pays tribute to our nation's veterans, active duty service men and women, transitioning military, military families and patriotic supporters. The inspirational and educational series offers insightful discussion, resources and solutions for the ongoing issues our veterans face daily.

The Salute to Veterans Series features a spirited group discussion with veterans about what it means to serve our nation, veteran employment, applying lessons learned from the military into the professional workforce, veteran education, the benefits of the Forever GI Bill for veterans and military families, preparing for the transition from the military to civilian life and much more.

Each of the veterans in the series share their personal stories of military service, and their experience finding success on the football field, both in college and in the pros. The veterans openly discuss their path forward, and offer their insight on important issues facing veterans and military families, and how they have found fulfillment and deep meaning in their lives — following their transition from the military.

Several topics and highlights include:

Veteran Employment — examples sharing how veterans' military experience relates to success in corporate America

Veteran Education — examples of how continuing your education can help continue your personal growth, development and career

The Forever GI Bill — examples of how the Forever GI Bill can help you make the most of the opportunities in front of you and your family

Military Service Dogs — examples of how military service dogs are matched with veterans, and the success stories of how military service dogs have positively impacted veterans and military families

Veterans in the Community — examples of how veterans can continue to advocate for our military service men and women following their service in the military

"We all owe a great debt to our military personnel who have served, and who are continuing to serve around the world in defense of our great country, and the many freedoms we enjoy every day. We hope these stories move, motivate, educate and entertain our 22 million veterans, 89 million direct military family members and patriotic supporters." Visit Salute to Veterans to learn more about the veterans series.

Financial health is a cornerstone of Navy Federal's mission of serving and enriching lives within the military community, and a key component of Navy Federal's Corporate Social Responsibility Strategy is financial wellness. Building wealth takes consistent action over time, and we're here to support you at every stage of this exciting journey. Continue to educate yourself about financial topics like savings, budgeting and investing with our MakingCents resources at navyfederal.org/makingcents.html.

Established in 1933 with only 7 members, Navy Federal now has the distinct honor of serving over 12.3 million members globally and is the world's largest credit union. Membership is open to all Department of Defense and Coast Guard Active Duty, veterans, civilian and contractor personnel, and their families. For more information about Navy Federal Credit Union, visit navyfederal.org.

At Verizon, we're proud to support our brave men and women and the families who stand beside them. It's our honor and privilege to keep military families connected, with special discounts for the military community — including active duty service members, veterans and Gold Star families. Get great deals on your mobile, internet or bundle them both for extra savings. For more information, visit verizon.com/military/.

Verizon Simplicity Plan. One plan. One price. Our best network. Just $30/line/month after Auto Pay and switch discount. Simplicity Plan gives you everything you want in a plan — 5G Unlimited Ultra Wideband, unlimited data, talk & text, Verizon Dollars and lots more. For more information, visit verizon.com/plans/unlimited.

To help you stay hydrated and energized during hot-weather travel, Registered Dietitian and Nutritionist Dawn Jackson Blatner shares her simple, everyday travel tips so you can make the most of every summer vacation.

Give your water a flavorful twist

Adding delicious and refreshing flavors to your water is a great way to encourage consistent hydration throughout your travels. You can easily upgrade your hydration game by squeezing fresh lemon and adding an electrolyte pack into your water. Lemon provides a zesty, citrusy taste and offers a little boost of vitamin C to help you meet your hydration goals throughout the day.

You can even try experimenting with other fun flavor combinations like cucumber and mint or strawberries and basil.

Eat when the locals do

Traveling across time zones can be hard on your body. To help minimize jet lag, Blatner recommends transitioning to local meal times as soon as you possibly can.

Eating meals and snacks according to your destination's schedule can help align your body's natural rhythms with the new time zone. This simple shift makes it much easier to maintain your energy levels during the day and get quality sleep at night during your trip.

Load up on hydrating food

Hot weather increases fluid losses through sweat, so don't rely on beverages alone to stay hydrated. Blatner recommends pairing protein-rich meals with hydrating fruits and vegetables like berries, watermelon, cucumbers, tomatoes and leafy greens to help boost both hydration and nutrition during hot-weather travel.

Pro tip: Summer is peak berry season, making it the perfect time to enjoy them while you travel. Berries naturally provide hydration, fiber and antioxidants, so try adding them to your meals and snacks whenever possible during your summer travels.

Prep on-the-go snacks

When you're on the road, convenience is key. Instead of relying on roadside gas station fare, Blatner suggests preparing simple and nutritious meals and snacks you can have on the go.

One easy way to fuel your summer adventures is with these Fitness Snack Packs Dawn created with Eggland's Best. Packed with protein and fresh seasonal produce, it's a simple snack that helps you stay on track with your health goals while you're on the go.

The recipe uses Eggland's Best eggs, which contain more than double the Vitamin B12 compared to ordinary eggs, supporting natural energy throughout your busy summer days. They also contain 25% less saturated fat than ordinary eggs, making them a smart addition to a balanced diet.

Fitness Snack Packs

Prep time: 5 minutes

Makes: 4

Ingredients

• 8 Eggland's Best Eggs
• 2 cups fresh berries
• 1 cup whole grain pretzels
• 2 cheese sticks, cut into bite-size pieces

Preparation

1. In a medium pot, add water and bring to a boil.
2. Reduce heat to a simmer, add eggs and simmer for 12 minutes.
3. Drain the eggs, put them into an ice bath to stop the cooking, and then peel.
4. Line up four meal prep containers, and to each add 2 hard-cooked eggs + 1/2 cup berries + 1/4 cup pretzels + 1/2 cheese stick, cut in pieces.
5. Store snack packs covered in the fridge for up to 5 days.

Additional Notes:

1. Time saver: Buy EB hard-cooked eggs
2. Use your favorite berries or swap to 1 peeled clementine/mandarin orange
3. Swap pretzels for whole grain crackers, if you prefer
4. Use your favorite type of cheese stick like mozzarella, cheddar or jack

This summer, don't let your good habits go by the wayside. Using these expert tips, you can enjoy your adventures and stay hydrated and energized, no matter where your trips take you. To find more easy, nutritious recipes to support your summer travels, visit EgglandsBest.com.

Instead, after the first few months of feeling open and flexible, his days became harder to navigate. He still exercised, ran errands and kept up with friends. Yet mornings stretched longer, and evenings arrived without much to distinguish one day from the next.

There was no single shift that caused concern. He felt a gradual drifting, and the questions that followed were practical: How do I organize my days now? What is this next chapter for?

'I could keep going, or I could turn back'

Victor Strecher, PhD and professor at University of Michigan School of Public Health, had grappled with those same questions too, but for entirely different reasons.

In 1990, Vic's newborn daughter Julia became seriously ill from a heart condition. Doctors told him she might have only a month or two to live. There was a slim chance for a heart transplant, but the odds were daunting. Even if Julia lived only a few years, Vic and his wife asked themselves whether they could still give her a life worth living.

They decided they could. Vic shifted his focus from career milestones to what would make her days full.

Julia survived into young adulthood, but at 19, she died unexpectedly. Vic lost his footing. Grief showed up as a numb routine: hours of television, drinking, a sense of dissolving.

One early morning, he climbed into a kayak on Lake Michigan and paddled out alone in the dark. As the sun rose and the water turned glassy, he sensed a choice. "I could keep going, or I could turn back," he said. "But if I turned back, I would have to live differently."

He turned back. "I went home, pulled out a sheet of paper and wrote, 'Vic, you have to help yourself.' Then I asked: 'What are you going to do?'"

He listed what mattered most — family, friends — then asked what mattered at work. His answer came quickly: his students. Vic called his university and asked to return to teaching. He committed to teaching every student as if they were his daughter.

Rebuilding a relationship with purpose

Without realizing it, Vic had begun rebuilding his relationship with purpose. He found having purpose changed not just the course of his life, but also the quality. He found greater clarity, a deeper connection, and more meaningful intentions.

"Purpose helps you organize what matters most. It directs your attention and energy toward that," Vic said.

When he researched the impact of purpose in other people's lives, he found the science backed him up.

In one study, participants wore identical 25-pound backpacks and estimated how steep a ramp appeared. One group was told the backpack was "dead weight." The other was told it carried important scientific equipment. Although both packs weighed the same, those who believed the load had meaning perceived the slope as less steep.

Other research linked a stronger sense of purpose with healthier coping strategies. People with greater purpose were more likely to walk, spend time in nature, engage in meaningful rituals and step back during stress. They were less likely to rely on habits that dulled stress in the moment. Studies following people after large-scale trauma found that those who rebuilt purpose showed greater resilience over time.

"When you have a sense of purpose, you're more likely to step back, see the bigger picture and remember this won't last forever."

An app for positive, lasting change

Surprisingly, Vic found purpose isn't a heroic vision or single-minded vocation a person is born with. It's a skill that can be clarified and strengthened, shaping daily behavior.

Always a teacher, Vic began looking for ways to share what he had learned. He wrote the book, "Life On Purpose", gave TED Talks and lectures including at Harvard School of Public Health, structured two online courses rated 4th best in the world by Inc. Magazine, and conducted pioneering research on life purpose, cited in the Journal of the American Medical Association.

In 2015, together with a team of psychologists, behavior designers and data scientists, he launched Kumanu (meaning "nourish" in Maori), a company designed to help people and organizations thrive by connecting deeply to what matters most through its app, Purposeful.

The app is based on decades of research across behavioral science, neuroscience, public health and organizational psychology and more than 1,400 scientific studies. It prompts users to address the aspects of their lives they'd like help with, and guides users through the same steps he took to create positive, lasting change: identifying values, writing a purpose statement and building habits that align with it.

Identifying values, such as family, health, faith, creativity, learning or service, creates direction. Putting those values into words shapes daily choices. From there, small practices create rhythm: a morning intention, a brief reflection, a consistent commitment. The consistency matters more than the scale.

"Users of Purposeful tend to be people who are going through transitions in their lives," Vic says. "I like to say you usually need to rethink your purpose when you need a Hallmark card."

What matters most now?

For users like John, it was exactly what they needed.

"Getting on Purposeful is part of my morning routine," a user said in a recent survey. "I have only missed a couple of days in the last year … it has really helped me stay in the present and be more focused and mindful about my days, relationships and my life."

For others navigating loss, like Vic, the structure has been equally meaningful. The app "gave me a place to share my grief and trauma of loss and channel it toward a meaningful experience … a helpful reminder to keep me connected and do basic self-care tasks," another respondent said.

For both, the shift began with the question "what matters most now?", choosing a direction and returning to it, one day at a time.

To learn more, listen to Vic's podcast, PurposeCast, where he explores the science and stories behind living with purpose. You can also try the Purposeful app with a free account — no credit card required. For those who choose to upgrade, a limited-time discount is available on Purposeful Premium: 29% off ($4.16 per month, billed annually at $49.99). Cancel anytime.

Photo above: Victor Strecher (R), with his daughter Julia Strecher (L) and wife Jeri Rosenberg.

For millions of Americans today, living with chronic disease is a daily struggle. Approximately three in four adults — which is about 194 million people — currently live with at least one chronic disease, including cancer, autoimmune diseases or neurological conditions.

Managing multiple or complex conditions is a challenge in itself, involving not only the patient, but also their family and caregivers in handling numerous medical appointments, monitoring their health and most importantly, following a treatment plan that can include keeping track of several prescriptions.

In fact, not following a doctor's guidance when taking prescriptions, also known as medical non-adherence, is a serious problem that can lead to poor health outcomes and potentially higher healthcare costs, especially for those who are coping with chronic diseases.

This is where a specialty pharmacy can make a difference for patients. Expert pharmacists and a streamlined system at a specialty pharmacy help to make care coordination, correct medication use, and the overall experience more positive than a traditional pharmacy. By simplifying many of the complexities associated with specialty medications, these services are designed to help patients focus more on their health and less on navigating the healthcare system.

Streamlined specialty service

One such service is BioPlus Specialty Pharmacy. Patients of BioPlus nationwide receive expert care to help them manage chronic and complex conditions with service and support that's faster, easier and more personalized.

If the prescription needs a prior approval, BioPlus will work with the doctor to get and submit any needed paperwork. Their quick and easy refill process, along with personalized care management tailored to patients' unique needs, also helps navigate financial assistance programs and medication access.

BioPlus patients have 24/7 access to pharmacists and a clinical care team for support, as well as a patient portal where they can view their medication and account status anytime. And, perhaps most importantly, the streamlined process uses secure shipping designed to protect specialty medications.

Both patients and healthcare providers benefit from the extra layer of support and safety provided by a specialty pharmacy.

"Managing chronic conditions is very challenging for patients and their healthcare providers. Unanswered questions about things like how and when to take medications can unfortunately make the patient experience even more difficult or unsafe," said Dr. Nicholas Maroulis, Senior Vice President of Pharmacy Services, BioPlus Specialty Pharmacy. "And for healthcare providers, excessive paperwork and communication problems can reduce the time that providers would rather be spending on patient care."

When patients receive the support they need to start and stay on therapy, they are better positioned to avoid gaps in care, helping improve the care experience and potentially reduce unnecessary, often higher-cost care.

When you might benefit from a specialty pharmacy

For numerous complex or chronic conditions such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, a specialty medication might be more complicated to use than what patients and caregivers are used to. For example, it might need to be injected or kept at a certain temperature in the fridge, or a medicine might come with side effects that require a little more care and support.

A specialty pharmacy that offers access to a team of dedicated experts can help patients use specialty medications appropriately and consistently while providing education and support.

Supporting patients confronting serious illness

When people are coping with a serious diagnosis such as cancer, simplifying access to medications and support can make it easier for them to stay focused on treatment and overall well-being.

"When a patient hears the word 'cancer,' everything changes. Beyond the diagnosis, patients have to navigate heightened emotions, uncertainty and questions, and some may be dealing with their diagnosis without any support," said Dr. Heera Persaud, PharmD, CSP and Director of Clinical Programs, BioPlus Specialty Pharmacy. "When we focus on patient-centered care, it's not just about the medication. It's about timing, guidance and making sure patients know that someone is there to help, even before they ask."

Learn more about specialized, personal pharmacy support for chronic and complex conditions at BioPlusRX.com.

• Homeowners are incorporating smart technologies throughout their homes, including solutions to improve indoor air quality (IAQ).
• Improving a home's IAQ typically involves using multiple products that don't work together.
• The Panasonic OASYS^® solves this problem by continuously bringing in fresh, filtered outdoor air that is balanced with indoor air to create a healthier living environment and improve IAQ, temperature and humidity.

Modern homeowners are steadily layering technology into every corner of their homes. Whether it's a smart thermostat, voice assistants, connected security, EV chargers or app-controlled appliances, smart technology is making home life easier and — in some cases — healthier.

Take indoor air quality (IAQ), for example. According to the U.S. Environmental Protection Agency (EPA), Americans spend on average about 90% of their time indoors, where the concentration of some pollutants is often two to five times higher than typical outdoor air. Although you can't see them, these air pollutants can have very real visible effects on your health and have been associated with:

• Irritation of the eyes, nose and throat.
• Headaches, dizziness and fatigue.
• Respiratory diseases, heart disease and cancer.

There are numerous smart devices on the market to improve IAQ, including monitors, purifiers, dehumidifiers and more. However, these separate IAQ technologies don't work together, requiring homeowners to monitor and adjust the settings themselves.

Seeing the need for connected IAQ technology that works in concert, Panasonic created OASYS^®, a whole-home air quality management solution that aligns comfort, air quality and energy management, providing homeowners with a true set-it-and-forget-it IAQ system.

Tech designed for integrated IAQ management from the start

Panasonic OASYS^® creates a house that breathes as intentionally as it was designed. The energy-efficient system manages indoor air quality, temperature and humidity without homeowner intervention. The result? Cleaner air, balanced humidity, fewer indoor allergens and pollutants, and consistent temperature control throughout the house from the moment you walk in.

So, how exactly does OASYS^® work to improve IAQ? It all begins with its fresh-air-first approach.

Improving ventilation with outdoor air is one of the fundamental strategies for reducing concentrations of indoor air pollutants. However, most home heating and cooling systems do not mechanically bring in fresh air. By flipping the traditional HVAC logic, OASYS^® provides homeowners with balanced airflow to every room, including hard-to-reach areas, supporting consistent comfort and well-being of families in their home environment.

Bringing in fresh air is especially important for homeowners who are moving into a new build. Construction materials, paint, new furnishings and cleaning products emit chemical vapors known as volatile organic compounds (VOCs), a common source of air pollution. By incorporating OASYS^® into building plans from the beginning, the whole-home air quality management system can reduce exposure to harmful chemicals by removing VOCs from paints, cleaning products and furnishings before you even move in.

Another benefit of OASYS^® is that it uses significantly less energy than conventional HVAC technologies. This isn't theoretical. In fact, Panasonic built the Panasonic OASYS^® Concept Home in Houston, Texas, as a proving ground for the system. By actively removing pollutants, allergens and excess humidity in Houston's challenging climate and air quality environment, OASYS^® supports better respiratory health and reduces energy consumption by up to 53% compared to traditional HVAC systems.^*

Homeowners aren't the only ones who can benefit from installing OASYS^® technology in their homes. For builders and developers, it provides a compelling alternative to standard HVAC, combining energy efficiency, resilience and occupant wellness in a single solution that doesn't require users to monitor and adjust settings constantly.

Other OASYS^® features that contribute to whole-home wellness include:

• Continuous ventilation: Provides a steady flow of fresh air, reducing indoor air stagnation, airborne pollutants and improving overall air quality.
• Dehumidification: Steady, balanced humidity levels to prevent mold, mildew and structural damage.
• Allergen reduction: Filters out pollen, pet dander, dust mites and other asthma triggers — ideal for sensitive individuals.
• Low maintenance: Designed for reliability and ease of use, with intuitive smart controls that require minimal upkeep.

Because OASYS^® combines multiple products into one cohesive system, ongoing maintenance is simple, predictable and designed to support long-term, whole-home air quality management. Best of all, it operates in the background, reflecting a growing preference for homes that are not just connected but thoughtfully integrated.

Whole-home comfort completes the modern, high-performance home

A cleaner, more comfortable home that supports holistic wellness doesn't happen by accident. It's built that way from the start, with smart technology that works together and does the work for you. For more information on the benefits of Panasonic OASYS^®, visit: iaq.na.panasonic.com/oasys.

*Based on a July 2024 analysis commissioned by Panasonic comparing the OASYS solution against conventional system designs, using a two-story, 4-bedroom, 3.5-bathroom house with light concrete tile roofing and a ventilated crawlspace underneath the first floor as the model home. Energy savings compare a Panasonic high-efficiency design, including an OASYS high-efficiency custom HVAC system and high-performance envelope, to a code minimum house design utilizing a standard gas furnace. Energy demand was converted and standardized to kilowatt hours (kWh), with the model estimating 5,932 kWh annual energy consumption for the OASYS system compared to an estimated 12,744 kWh annual energy consumption for the conventional system, a reduction in annual energy consumption of 53%. The U.S. Department of Energy's IES Virtual Environment software was used to produce an HVAC load sizing report, while the building's energy usage was assessed with the National Renewable Energy Lab's BEopt tool.

Understanding achondroplasia

Achondroplasia is the most common form of skeletal dysplasia (short-limbed, disproportionate short stature). At its core, the condition is caused by a specific gene variant that alters bone development and is expressed in tissues throughout the body.

Physically, people with achondroplasia typically have a long, narrow trunk, a larger head and shorter arms and legs. As children grow, these physical differences can shape how they interact with the world around them. Everyday milestones and activities, such as reaching a high shelf, using the bathroom independently, or participating in active play or sports may require adaptations and extra support.

The path to diagnosis and early monitoring

For some families, the journey begins before their child is even born, as achondroplasia can sometimes be suspected during pregnancy based on ultrasound findings. Genetic testing may be used to confirm the diagnosis before or after birth. In other cases, the diagnosis comes after birth and may involve a physical examination, imaging such as X-rays, and genetic tests.

Whenever the diagnosis occurs, early diagnosis is a crucial first step. It helps families to proactively partner with their child's healthcare team to monitor growth and watch for potential complications over time.

"While achondroplasia is often thought of primarily in terms of height, it can affect multiple systems throughout the body," explains Dr. Chaya Murali, Pediatric Geneticist, Baylor College of Medicine. "Medical complications of achondroplasia may vary across different stages of life and differ between individuals, which is why ongoing monitoring and individual care are vital."

Looking at the whole picture: health considerations

As Dr. Murali notes, achondroplasia is about much more than just bone growth. It can also impact muscles, nerves, and breathing. Because achondroplasia affects each person differently, potential medical complications may vary across different stages of life and differ between individuals.

Throughout their lives, individuals may face an increased risk for specific health challenges, including spinal abnormalities and impaired muscle strength. Some of these complications may persist or evolve as a child grows into an adult and may occasionally require multiple medical procedures and surgeries to address specific functional or anatomical concerns.

Ultimately, these medical factors, combined with social and individual influences, can play a significant role in a person's physical functioning, psychosocial well-being, and overall quality of life.

A team approach to individualized care

Because achondroplasia touches multiple systems in the body, care is rarely a solo endeavor. It often involves a multidisciplinary healthcare team, which may include pediatricians, geneticists, endocrinologists, ear-nose-throat specialists, neurosurgeons, sleep specialists, and orthopedic specialists.

Historically, the primary management approach has focused on closely monitoring the child and addressing complications as they arise. However, medical decisions remain deeply personal and are never one-size-fits-all. Families are encouraged to speak with their healthcare provider to determine the most appropriate approach for their child.

Determining your approach and finding support

Parents are encouraged to speak openly with their healthcare providers to map out the most appropriate care approach for their child. Beyond the clinic, finding supportive communities and accessing accurate, reliable information can help families confidently track their child's progress and navigate ongoing healthcare discussions.

To learn more about achondroplasia, visit: https://askaboutachondroplasia.com/.

Featured in the photo are Lawson (age 4) and his mother, Chelsea.